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Ameliorative effect of sixteen weeks endurance training on biochemical and oxidative damage in high fat diet induced obese rats
Get PDFObesity is mainly caused by consumption of high fat diet (HFD) and a lack of physical activity. Physical activity is an efficient strategy to delay development of obesity. In this studyv we tried to evaluate attenuating properties of 16 weeks endurance training on plasma oxidative stress and some biochemical parameters in HFD induced obese rats. Twenty-four male Wistar rats were randomly divided into four groups: standard diet group (SD), standard diet with endurance training group (ESD), HFD group and HFD with endurance training group (EHFD). After sixteen weeks, plasma was prepared and evaluated for measurement of different parameters. The results showed that HFD significantly decreased the activities of superoxide dismutase (33.58%), catalase (26.51%) and glutathione S-transferase (22.77%), while endurance training increased these enzymes activities. However, exercise ameliorated the increased malondialdehyde level and depletion of glutathione. In addition, it significantly reduced the increased levels of liver enzymes activities and lipid profiles. These findings suggest that endurance training has found to have beneficial effects against HFD-induced oxidative damage through increasing reduced antioxidants levels and inhibition of lipid peroxidation due to its antioxidant property. Thus, it can be considered an interesting strategy for the management of obesity related diseases
Synthesis and evaluation of biological activity of some novel carbazole derivatives
Get PDFNatural and synthetic carbazoles contains potent activity against inflammation. Some novel carbazole derivatives have been synthesized and also checked for activity against inflammation by using Carrageenan Induced Inflammation in Rat Paw Edema Model. Structures of synthesized carbazole derivatives have been confirmed on the basis of FT-IR, 1H NMR and elemental analysis. During the evaluation of biological activity, newly synthesized compounds (4a) and (4f) are found more potent against inflammation
The Effect of Different Molar Ratios of CeO2 on Photoluminescence Properties of CeO2/TiO2 Nanoparticles
Get PDFThe CeO2-TiO2 nanoparticles were prepared by a combination of hydrothermal and sol-gel preparation methods. the bond structures and crystal properties of the obtained materials were featured with X-ray diffraction, FTIR, Raman, and Bet analysis; surface morphologies were examined with the help of FESEM and STEM. And finally, the PL properties of the synthesized samples were also examined in this study. The excitation and emission spectra of 0.1 mol% and 0.25 mol% CeO2 doped TiO2 phosphors consist of broad bands in the UV (200–300 nm) region with maxima at 254 nm. The excitation band at 254 nm is defined as the charge transfer band (CTB). In the emission spectra, a broadband located from 400 to 700 nm is related to the 5d-4f (5d1→4f1) transition of Ce3+ in TiO2. According to the PL result, the 5d–4f transition of Ce3+ is heavily dependent on the concentration of Ce3+ in the host crystal TiO2
Performance test of dual fuel engine using octagonal with algae biodiesel
Get PDFIn comparison to internal combustion engines, diesel engines are high thermal-efficient. However, the application of diesel engines is still dependent on fossil fuels. This fuel has limited availability and the effects are also very dangerous, especially its emission. Octagonal has been used as an alternative fuel to replace fossil-based diesel fuel. The purpose of this work is to explore the performance of the dual fuel engine-octagonal diesel. The performance test has been carried out by running the indirect injection engine that is modified to direct injection at 1500 rpm using four types of like diesel fuel, and diesel mixed with octagonal 2.5, 5 and 10%. The results show that there was an increasing effect of engine-indicated mean effective pressure (IMEP) value and brake-specific fuel consumption (BSFC) reduction when the engine is operated using octagonal diesel fuel blends. The emission of hydrocarbon (HC) tended to increase, while the emission of smoke and carbon monoxide (CO) decreased when the engine is operated using dual fuel-octagonal diesel
Biodegradable curative film for medical application
Get PDFAn attempt has been made to produce a herbal based silk fibroin – chitosan biodegradable film. Herbs are used for wound healing purpose, silk fibroin for its remarkable bio-medical and mechanical properties and chitosan for its antimicrobial properties. Herbal extracts, such as Aloe barbadensis Mill, (Aloe Vera), Cissus quadrangularis (Pirandai), and Curcuma longa (Turmeric) have been used to impart wound healing effects. The physical and antimicrobial properties have been studied as per the standard methods. The cytotoxic reactivity of the test, and control sample are evaluated under an inverted phase contrast microscope based on the standard. Scanning electron microscope is used to study the morphology of prepared film for process versatility and highly specific surface area. The chemical compound assessments are studied by Fourier Transform Infrared. Microbial growth under the bio films is found to be absent, and test results show better activity against Escherichia coli and Staphylococcus aureus. The blended film shows none cytotoxic reactivity to fibroblast cells and test silk fibroin blended film shows slight cytotoxic reactivity to fibroblast cells after 24 h contact. The achievement of numerical more than 2 is considered as cytotoxic effect. Since the film samples achieve a numerical grade not greater than 2, the samples are considered as non cytotoxic. Microbial growth under the bio films is found to be absent and test results show better activity against Escherichia coli.
Effect of plasma treatment on polyester knitted fabrics: Part II — Moisture management properties
Get PDFThis study focuses on the moisture management properties of plasma-treated polyester knitted fabrics (spun, continuous filament, micro denier and hollow fibre). The effect of different loop lengths and the impact of oxygen plasma treatment on the moisture management properties of the fabric has also been studied. The moisture management properties are better for the plasma-treated fabric and also for the fabric having highest loop length. The moisture management properties of the fabric have been improved with the oxygen plasma treatment.
Aloe vera gel finished 3D spacer knitted sports textiles
Get PDFIn this study, polyester fibre is converted to 3D spacer knitted fabric of fully hydrophobic in nature. In this study, polyester fibre has been converted in to 3D spacer knitted fabric which is fully hydrophobic in nature. The silicone based hydrophilic softeners are applied on the surface of one side of 3D spacer fabric to make it hydrophilic layer using spraying techniques. The hydrophilic layer of 3D spacer fabric is then finished with aloe vera gel for its use in sportswear. Bioactive compounds available in aloe vera gel, such as tannin, phenols, saponins, terpenoids, and flavonoids, have been tested using a thin layer chromatographic technique. Aloe vera gel extract and gel finished fabrics are assessed for antibacterial activity by using agar well diffusion method and parallel streak method. The test results provide excellent antibacterial property at the inhibition zone of 33mm against Escherichia coli and 35mm against Staphylococcus aureus. Physical and comfort properties of aloe vera gel finished spacer fabric and normal polyester knitted sports fabric are assessed using ASTM and AATCC standards. The test results obtained from aloe vera gel finished spacer fabric are found higher with respect to fabric thickness, fabric weight, water vapour permeability, bursting strength, vertical wickability, and air permeability as compared to normal polyester knitted sports fabric. It can also be used for protective textiles, agro textiles, aerospace textiles and medical textiles
Effect of varying cycle time interval and aerosol pre-charge on filtration performance of polyester media
Get PDFPresent study embodies filtration characterization of two nonwoven needle-felt polyester filter materials, viz. PTFE coated and without coated media. The materials have been assessed using flyash aerosol under varying time intervals (6, 9 and 12 min) at different inlet dust densities (50, 90 and 150 g/m3). The flyash particles are charged prior to their deposition over the filter media using a three phase parallel plate box pre-charger at two different levels of pre-charge, viz. 4 kV and 8 kV along with 0 kV. Results reveal that the filtration performance for PTFE coated material is better under all conditions. However, an enhanced filtration performance in terms of particle emission and pressure drop is noted at increased pre-charge level and higher cyclic interval. It may also be noted that the level of improvement in filtration behavior for both the materials has been better at initial level of pre-charge from 0 kV to 4 kV. However, the cumulative behavior of all the factors is also found significant.
Enhancement of Thermal Insulation and Mechanical Properties of Concrete by Expanded Polystyrene Beads
Get PDFThe aim of this work has to study the thermal properties of concrete by adding Expanded Polystyrene Beads (EPS) in the normal concrete. EPS and granite dust have replaced for fine aggregate by 25% and cement by 10% by weight. Glass fibres have also added at 0%, 0.05%, 0.1%, 0.15%, 0.2%, 0.25%, 0.3% and 0.6% by the weight of cement. The effect of EPS, granite dust and fibres on mechanical properties, durability and thermal conductivity have studied. The results have showed that on adding EPS, reduced the thermal conductivity, weight, water absorption and strength of the concrete than the normal concrete. The reduction in strength of nominal concrete by the addition of EPS was15%, which have compensated by adding 0.15 % of glass fibre
In silico study of CYP450 inhibitor activity of (E)-1-(3-((4-chlorophenyl) diazenyl)-4-hydroxyphenyl)ethanone
Get PDFMolecular docking and single crystal study of azo dye (E)-1-(3-((4-chlorophenyl)diazenyl)-4-hydroxyphenyl)ethanone (3) is reported here. It has been synthesized by diazotization of 4-chloroaniline followed by coupling with 4-hydroxyacetophenone. Molecule is almost planar with acetyl as well as azo groups only slightly deviating from the plane of C3–C8 phenyl ring as evident by C1–C2–C3–C8 and N2–N1–C7–C6 torsion angles of –3.6(3)° and –3.9(3)°, respectively. Torsion angle N1–N2–C9–C14 between azo group and chlorophenyl ring is somewhat larger being –13.1(3)° leading to torsion angle between phenyl C3–C8 and chlorophenyl C9–C14 ring of 17.26(11)°. Intramolecular O2–H2···N2 hydrogen-bonding is observed here. Pillars along b-axis are formed due to π∙∙∙π stacking interactions of parallel molecules in head-to-head fashion with centroid-to-centroid distance of 3.8829(14) Å and ring slippage of 1.416 Å. Title compound shows good binding affinity towards six enzymes of CYP450 family. Both nitrogens of the azo bond show significant involvement in bonding interactions with proteins in case of all the six enzymes