Journal Universitas Wijaya Kusuma Surabaya
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Pengaruh Keadilan Organisasi Dan Pemberdayaan Karyawan Terhadap Komitmen Organisasi Melalui Kepuasan Kerja
Get PDFThe purpose of this research was to determine and explain the effect of Organizational Justice and Employee Empowerment on Organizational Commitment through Job Satisfaction among Employees of PT Kharisma Baru Indonesia. This study used a quantitative approach with a sample of 32 respondents at PT Kharisma Baru Indonesia employees and used Partial Least Square (PLS). The results of this research were organizational justice has no effect on organizational commitment, organizational justice has a significant positive effect on job satisfaction, employee empowerment has a significant positive effect on organizational commitment, employee empowerment has no effect on job satisfaction, job satisfaction did not affect organizational commitment, job satisfaction did not mediate the effect of organizational justice on organizational commitment, job satisfaction did not mediate the effect of employee empowerment on organizational commitment
Minat Investasi Saham Perusahaan Go Public Pada Era Pandemi Covid-19
Get PDFFormulation of the problem in this study is whether behavioral attitudes, subjective norms, income and stock market prices affect the interest in investing share of go public companies in covid 19 pandemic and which of these factors has the greatest contribution to interest in investing in go public companies. Research sample of potential investors who’re interested in investing go public companies in era covid 19 pandemic. There are 127 samples, same with the answers to the returned quesioner. The variable include independent variables behavioral attitues, subjective norms, income, and stock market prices. Dependent variabel is interest in stock investment. The research analysis model uses a multiple linear regression model with econometric evaluation with classical assumptions including multicollinearity test, heteroscedasticity test and autocorrelation test. While the hypothesis testing using t-test and determination test with a significant level of 5%. The test result show the significant value of all factors below 5%, so the fisrt hypothesis is accepted. Bevarioral attitudes, subjective norms, income and stock market prices individually have a significant effecr on investment interest in go public companies in the era of covid 19 pandemic. The second hypothesis is accepted because the value of coefficient of determination of the stock market price factor is the largest, which is 0,991 or 99,1% , so the stock market price factor has the largest contribution on investing go public companies era covid 19 pandemic
ASPEK LABORATORIUM Acute Promyelocytic Leukemia (APL) AML-M3
Get PDFAcute Promyelocytic Leukemia (APL) adalah subtipe M3 dari Acute Myelogenous Leukemia (AML), sesuai klasifikasi French-American-British (FAB). APL mempunyai beberapa varian yang bisa dibedakan dari pemeriksaan molekular dan sitogenetika. Lebih dari 95% APL hipergranular (M3 klasik), 15%-20% dari APL adalah varian mikrogranular (hipogranular, M3v) dan varian APL yang jarang (<1%) adalah basofilik dan Promyelocytic leukemia zinc finger (PLZF/M3r).Gejala klinis penderita APL yakni anemia meliputi pusing, kelelahan, sesak ketika kerja fisik, pucat. Perdarahan terjadi karena pasien dengan APL mengalami penurunan jumlah trombosit dan gangguan sistem koagulasi. Sel darah putih pada umumnya meningkat ditandai dengan gejala panas badan dan infeksi serta pembesaran limpa juga nyeri tulang akibat infiltrasi sel-sel leukemia ke periosteal.Tes skrining penderita leukemia akut adalah pemeriksaan darah rutin dan evaluasi sediaan hapusan darah tepi. Pemeriksaan penunjang diagnostik lainnya adalah hapusan dari aspirasi sumsum tulang, pengecatan sitokimia, Immunophenotyping, sitogenetika dan biologi molekular. White blood cell (WBC) > 10 X 109/L, trombositopenia < 50 X 109/L. Hapusan darah tepi pasien dengan APL didapatkan gambaran eritrosit normokromik normositik dengan poikilositosis dan kadang-kadang normoblas. Gambaran sel-sel muda didominasi oleh promielosit. Sebagian besar hipergranular, morfologi mieloblasnya dengan nukleus berlekuk dan Auer rod. Pada hapusan sumsum tulang umumnya hiperseluler dengan jumlah sel-sel muda promielosit ≥30%. Morfologi promielosit pasien dengan APL lebih besar daripada promielosit normal. Auer rods positif kadang-kadang didapatkan faggots cell. Aktivitas eritropoiesis dan trombopoiesis tertekan. Varian hipergranular APL diketahui dengan pemeriksaan sitokimia, immunophenotyping, sitogenetika dan teknologi biologi molekuler
REACTION BIOMARKER MONOCLONAL FRAGMENTATION OF COLLAGEN TYPE IV WITH BLOOD SERUM ACUTE MYOCARDIAL INFARCTION PATIENT RELATED INFECTION
Get PDFPenelitian ini bertujuan untuk mendeteksi penyakit jantung akut myocardial infark dengan menggunakan biomarker antibodi monoclonal fragmentasi kolagen tipe IV. Rupture plak aterosklerosis adalah terjadi karena degradasi kolagen tipe IV. Perviromonas gingivalis adalah salah satu faktor resiko yang terpenting untuk terjadinya akut myocard infark (AMI). Rancangan penelitian ini adalah ekperimental invitro dengan deksriptif cross sectional. Sampel penelitian adalah empat orang sehat (n=4) serta 12 penderita AMI (n=12). Untuk melihat ekpresi enzim MMP-9 dan fragmentasi kolagen tipe IV, kami menggunakan teknik western bloting. Untuk mengisolasi sel limfosit, kami mengimunisasi mencit dengan antigen fragmentasi kolagen tipe IV disertai dengan adjuvant. Selanjutnya dilakukan fusi antara sel limfosit dengan sel myeloma sehingga terbentuk hibridoma dan diuji dengan western bloting serta ELISA teknik. Kemudian dilakukan seleksi klon. Selanjutnya dilakukan insersi pada intra peritoneal sehingga terbentuk ascites. Hasil penelitian ini menunjukkan bahwa MMP-9 muncul pada 92 kDa dan fragmentasi kolagen tipe IV dengan band 60 – 80 kDa. Untuk menguji reaksi monoklonal antibodi fragmentasi kolagen tipe IV dilakukan uji 12 sampel penderita AMI. Hasilnya semua sampel AMI positif. Kesimpulan menunjukkan bahwa biomarker monoklonal antibodi fragmentasi kolagen tipe IV ternyata bereaksi positif pada penderita AMI
EXERCISE STRESS TESTING : WHEN, HOW, AND WHAT IT MEANS?
Get PDFExercise stress testing (EST) is a sensitive and informative examination of the cardiovascular response to exercise. Exercise is a common physiological stress used to elicit cardiovascular abnormalities not present at rest and to determine the adequacy of cardiac function. The electrocardiogram is the most common parameter used to evaluate the ischemic response during exercise. Exercise electrocardiography is one of the most frequent noninvasive modalities used to determine the likelihood and extent of coronary artery disease. The test is also used to estimate prognosis, to determine functional capacity, and to evaluate the effects of therapy. The indications, contraindications, protocol, when to terminate, interpretation of the result, and spesific clinical applications will be reviewed in this paper
TYFOID FEVER
Get PDFTyphoid fever is a bacterial infectious disease caused by Salmonella typhi. The disease is transmitted through food or water contaminated by feces or urine of people who terinfeksi.Gejala clinical, among others, heat, and complaints of the gastrointestinal tract. Diagnosis based on a diagnose and blood. These diseases include infectious diseases that require antibiotics for treatment. Complications include the complications that can cause intestinal and extra intestinal. At this time have found a vaccine that can prevent this disease typhoid fever
HEALTH
Get PDFA healthy human is not only a sound body, but also spiritually healthy. So healthy and ideal body in terms of health aspects of physical, mental and social and not only free of disease (WHO Definition of Health 1950). All these aspects will affect the appearance or performance of each individual, in performing daily activities like work, work, be creative and do things that are productive and useful. Health, education and income of every individual are the three main factors which influence the quality of human resources. Therefore, every individual has the right and must always maintain good health, which is the main capital in order to live productive, happy and prosperous
Literature Study: Effectiveness of Scabies Treatment Using Natural Ingredients
Get PDFThe skin is the outermost organ that is often exposed to the external environment, which can cause skin diseases, one of which is scabies. Scabies is caused by the mite Sarcoptes scabiei var hominis and its products. often found in densely populated environments, such as Islamic boarding schools and communities with poor personal hygiene quality or tend to be poor, and low economic status. For management, administration of drugs is generally topical to kill the mites that cause this disease. However, it has limitations, such as the relatively expensive price, so that alternative medicine materials with relatively cheaper costs are needed, namely medicines made from plants. The purpose of this study was to evaluate publications on the effectiveness of scabies treatment using natural ingredients. Methods: This study uses a literature study method in obtaining information or data from journals and research documents. The results of the literature study indicate that the use of traditional medicine is effective in the healing process of scabies. The use of traditional medicine is effective in curing scabies but as a complement to the use of topical drugs
Hubungan Tingkat Activity Daily Living (ADL) dan Kualitas Hidup Lansia di Magetan
Get PDFMost chronic diseases begin to appear in the elderly. Physiological decline in the elderly will also have an impact on the daily activities of the elderly. Dependence on other people is needed by most of the elderly in carrying out daily activities. This will directly affect the quality of life for the elderly. This study aims to analyze the relationship between the level of Activity Daily Living (ADL) and quality of life in the elderly group in Magetan. This research method is observational using a sample of 80 elderly people. Data were collected by purposive sampling in accordance with the inclusion and exclusion criteria in the study. The daily activity assessment process uses the Activity Daily Living (ADL) questionnaire, while the quality of life assessment also uses a questionnaire which is divided into four domains (physical, psychological, social and environmental). The research data obtained will be tested for correlation using the Spearman test. The results of the Spearman test analysis showed that there was a positive correlation between Activity Daily Living (ADL) on the four domains (physical, psychological, social and environmental) on quality of life (p<0.05). In the four domains, there was a relationship (correlation) with ADL, namely the physical domain (r=0.560), psychological domain (r=0.463), social domain (r=0.415), environmental domain (r=0.340). So it can be concluded that there is a relationship between Activity Daily Living (ADL) on the four domains, namely physical, psychological, social and environmental. However, the physical domain has the greatest influence on the daily activities of the elderly
Penggunaan High Flow Nasal Cannula sebagai Terapi Oksigen pada Kasus Covid-19 Berat dengan Obesitas: Laporan Kasus
Get PDFCoronavirus Disease 2019 (COVID-19) is a disease which caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). In December 2019, this disease was encountered in Wuhan, China. Covid-19 is still a global pandemic to this day. Obesity is one of the comorbidities which has been shown to increase the severity of COVID-19 cases. There is research which stated that invasive mechanical ventilation may contribute to mortality rate in severe case of COVID-19. Other than that, the increase rate of severe COVID-19 cases and the limited availability of facilities and infrastructure makes the usage of high flow nasal cannula (HFNC) begins to be considered. Aim of this case report is to represent the outcome of obese COVID-19 patient whom treated with HFNC, furthermore could evoke readers to take further research of the effectiveness of HFC usage as an oxygen therapy in severe COVID-19 cases. Case summary: 21 years old woman came to Emergency Department in Wangaya Regional Hospital with shortness of breath, unproductive cough, sore throat, and inability to smell. Patient was treated and diagnosed with confirmed severe COVID-19. She got obesity as comorbidity (weight 105 kg; height 160 cm; Body Mass Index (BMI) 41.02 kg/m2). Patient was treated for 15 days, which include 10 days of treatment in negative pressure ward in Intensive Care Unit Department (ICU). During the treatment course, patient received pharmacologic and non-pharmacologic treatment, including the administration of HFNC. After five days of HFNC usage, oxygen supplementation was downgraded to conventional oxygen supplementation (non-rebreather mask and nasal cannula). Patient then discharge without any complain and proceed self-quarantine at home. HFNC could be considered as one of non-invasive oxygen supplementation treatment in patient with severe COVID-19 disease. The initiation of usage of HFNC could be started with 30 L/minute flow, with 40% fraction of inspired oxygen (FiO2) in accordance to patient comfort with Sp02 target 92-96%. If there is an increased breathing effort, high respiratory rate, and unachieved Sp02 target, flow and inspiration fraction titrated gradually. ROX index could be used as a treatment failure indication and the need of invasive ventilation