OBGYNIA - Indonesian Journal of Obstetrics & Gynecology Science
Not a member yet
371 research outputs found
Sort by
Multigravida Post-Partum dengan Inversio Uteri Subakut Komplit yang Ditatalaksana Histerektomi Supraservikal Pervaginam
Get PDFInversio uteri adalah salah satu komplikasi persalinan dengan risiko kematian tinggi akibat perdarahan dan syok. Laporan ini menjelaskan mengenai presentasi dan manajemen kasus inversio uteri. Seorang wanita berusia 33 tahun, P4A0 post partum spontan di bidan hari ke 5 dirujuk ke RS Mohammad Hoesin dengan riwayat uterus yang ikut keluar saat persalinan, namun uterus dapat dimasukkan kembali. Tanda-tanda vital pasien dalam batas normal. Pada pemeriksaan abdomen didapatkan tinggi fundus uteri sulit dinilai. Pada saat dilakukan inspeksi terdapat benjolan berupa keseluruhan uterus yang terbalik keluar dari serviks. Pemeriksaan laboratorium menunjukkan penurunan kadar hemoglobin (9.1 g/dL) dan peningkatan kadar leukosit (10.34x103/mm2). Pada pemeriksaan USG tidak tampak uterus pada kavum pelvis dengan kesan yang sesuai dengan gambaran inversio komplit. Pasien dipasangkan kateter lalu diputuskan untuk histerektomi supraservikal pervaginam. Kemudian pada pasien dilakukan pemasangan tampon vagina, pemberian antibiotik, antifibrinolitik serta obat simptomatik dengan stabilisasi berupa cairan dan transfusi. Setelah dua hari, tampon dilepas dan pasien membaik tanpa adanya komplikasi.Post-Partum Multigravida with Complete Subacute Uterus Inversion Treated by Vaginal Supracervical HysterectomyAbstractUterine inversion is one of labor complications with high mortality risk caused by bleeding and shock. This paper presenting the clinical manifestation and the management of uterine inversion. A 33-year-old woman, P4A0 spontaneous postpartum at midwife day-5 was referred to Mohammad Hoesin Hospital with uterine expulsion during delivery and the uterine could be re-inserted. Vital signs within normal limits. Abdominal examination showed unmeasurable uterine fundal height. Gyneclogical examination showed an inverted uterus mass outside the cervix. There was decreased haemoglobin (9.1 g/dL) and increased leucocytes (10.34x103/mm2) level. Ultrasonography measure showed no visible uterus in pelvic cavity with impression of complete uterine inversion. The patient was catheterized and decided for vaginal supracervical hysterectomy. The patient applied with vaginal tampons and prescribed with antibiotics, antifibrinolytics and symptomatic drugs with stabilization using crystaloid fluid and blood transfusion. After two days, the tampon was removed and patient improved without any complications.Key words: hysterectomy, uterine inversion, supracervica
ACE2 Receptors Finding in Placenta with Intrauterine Fetal COVID-19 Infection: A Meta-Analysis
Get PDFObjective: Association between ACE2 receptors in the placenta and the incidence of intrauterine COVID-19 infection in pregnant women infected with COVID-19 Methods: Systematic review and meta-analysis of placenta in pregnant women with COVID-19 infection, ACE2 receptor in placenta, and RT-PCR of neonates from COVID-19 pregnant women. This study followed the Preferred Reporting Items for Systematic Review and Meta-analyses (PRISMA) protocol. Results: 6 journals meet the inclusion criteria. ACE2 receptors were found in syncytiotrophoblasts 72/72 (100%), cytotrophoblasts 41/72 (56.9%), extravillous trophoblasts 24/72 (33.3%), decidual cells 2/72 (2.7%), villous stromal cells 1/72 (1.3%), and 1/72 stromal cells (1.3%) with the incidence of neonates infected with SARS-CoV-2 from pregnant women with COVID-19 10.5%, odds ratio (OR) between ACE2 receptors and neonates infected with COVID-19 is 1.97 (95%CI 0.05–81.09), the pooled proportion of ACE2 receptor findings in 72 placentas in pregnant women with COVID-19 infection, syncytiotrophoblast 98.3 (95% CI 94.3–99.9), cytotrophoblast 40.3 (95% CI 2.3–88.9), and extravillous trophoblast 35.2 (95% CI 0.2–88.5). Conclusion: Expression of ACE2 receptors is always present in the placenta of pregnant women, and there is an association but non-significant between ACE2 receptors in the placenta and the incidence of COVID-19 intrauterine infection with an odds ratio of 1.97 (95%CI 0.05-81.09).Reseptor ACE2 Pada Plasenta dengan Kejadian Infeksi COVID-19 Intrauterine Pada Fetus: A Meta-AnalysisAbstrakTujuan: Hubungan antara reseptor ACE2 di plasenta dengan angka kejadian infeksi COVID-19 intrauterine pada ibu hamil yang terinfeksi COVID-19. Metode: Tinjauan sistematis dan meta-analisis plasenta pada ibu hamil COVID-19, reseptor ACE2 pada plasenta, dan hasil uji RT-PCR neonatus dari ibu hamil COVID-19. Penelitian ini mengikuti protokol Preferred Reporting Items for Systematic Review and Meta-analyses (PRISMA). Hasil: 6 jurnal memenuhi kriteria. Reseptor ACE2 ditemukan di sinsitiotrofoblas 72/72 (100%), 41/72 sitotrofoblas (56.9%), trofoblas ekstravili 24/72 (33.3%), sel desidua 2/72 (2.7%), sel stroma vili 1/72 (1.3%), dan sel stroma 1/72 (1.3%) dengan insidensi neonatus yang terinfeksi SARS-CoV-2 dari ibu hamil dengan COVID-19 sebanyak 10.5%, odds ratio (OR) antara reseptor ACE2 dan neonatus terinfeksi COVID-19 adalah 1.97 (95%CI 0.05–81.09), proporsi gabungan penemuan reseptor ACE2 pada 72 plasenta ibu hamil COVID-19, sintiotrofoblas 98.3 (95%CI 94.3 – 99.9), sitotrofoblas 40.3 (95%CI 2.3 – 88.9), dan trofoblas ekstravili 35.2 (95%CI 0.2 – 88.5). Kesimpulan: Ekspresi reseptor ACE2 selalu ditemukan di plasenta ibu hamil, dan terdapat hubungan yang tidak bermakna antara reseptor ACE2 di plasenta dengan kejadian infeksi intrauterine COVID-19 yaitu odds ratio 1.97 (95%CI 0.05-81.09).Kata kunci : Infeksi COVID-19, Intrauterine, reseptor ACE2 plasenta
Profil Klinikopatologi Pasien Tumor Trofoblas Gestasional yang Dilakukan Operasi di RSUP DR. Hasan Sadikin Bandung Tahun 2017-2020
Get PDFTujuan: Mengetahui proporsi klinis dan histopatologi pasien tumor trofoblas gestasional yang dilakukan operasiMetode: Penelitian ini menggunakan desain studi deskriptif, dengan pengambilan data menggunakan total sampling. Kriteria inklusi adalah Pasien tumor trofoblas gestasional yang dilakukan operasi dengan data lengkap.Hasil: Total 27 kasus, didapatkan bahwa pasien tumor trofoblas gestasional yang dilakukan operasi sebagian besar memiliki kategori usia ≥40 tahun (59,26%), paritas multipara (66,67%), kehamilan sebelumnya mola (66,67%), interval dengan kehamilan sebelumnya >12 bulan (55,56%), kadar β-hCG sebelum operasi 103 -12 months (55.56%), β-hCG levels before surgery 103 -<104 mIU/ml (40.74%), the largest tumour size 5 cm (88.89%), no metastatic site (74.07 %), failure of multiple agent chemotherapy (74,07%), hysterectomy surgery (96.30%), β-hCG level after surgery <103 mIU/ml (77.78% ), and histopathological features of choriocarcinoma (88.89%).Discussion: In this study, it was found that all gestational trophoblastic neoplasia patients who underwent surgery had a FIGO/WHO score ≥7 which means high risk.Conclusion: The gestational trophoblastic neoplasia cases that underwent surgery in this study presented a clinical profile of multiparity, previous molar pregnancy, and failure of multiple agent chemotherapy with histopathological type of choriocarcinoma.Key words: Profile, gestational trophoblastic neoplasia, operatio
Diskrepansi Diagnosis Preoperatif dan Hasil Patologi Anatomi Postoperatif Serta Gangguan Pola Haid Pada Tuberkulosis Genital
Get PDFTujuan: Mengevaluasi diskrepansi diagnosis preoperatif dan hasil patologi anatomi postoperatif pada kasus tuberkulosis genital dan mengevaluasi gangguan pola haid yang terjadi.Metode: Penelitian ini merupakan studi deskriptif dengan pendekatan potong lintang terhadap pasien yang terdiagnosis tuberkulosis genital berdasarkan hasil patologi anatomi. Populasi diambil dari rekam medis pasien dengan diagnosis tuberkulosis genital berdasarkan kode ICD 10 yang sesuai dalam kurun Januari 2017 hingga Juni 2021. Sampel penelitian didapat secara total sampling, sesuai kriteria inklusi dan eksklusi yang ditetapkan. Dilakukan pembandingan diagnosis preoperatif terhadap hasil patologi anatomi postoperatif. Pasien dengan hasil histopatologi tuberkulosis genital kemudian diwawancara melalui telepon untuk memnetukan pola gangguan menstruasi berdasarkan kriteria FIGO 2018.Hasil: Terdapat 11 pasien dalam studi ini. Terdapat diskrepansi diagnosis preoperatif dengan hasil patologi anatomi postoperatif pada 6 pasien (54,55%). Pada pasien tuberkulosis genital ditemukan gangguan menstruasi berupa amenorea dan oligomenorrhea. Terapi tuberkulosis lini 6 bulan diberikan kepada 3 dari 5 pasien yang terkonfirmasi tuberkulosis genital. Kesimpulan: Terdapat diskrepansi pada penegakan diagnosis preoperatif dengan hasil patologi anatomi postoperatif pada tuberkulosis genitalia. Diskrepansi ini berdampak terhadap pilihan pengobatan pasca-operasi yang adekuat. Gangguan menstruasi yang terjadi pada tuberkulosis berupa oligomenore diikuti oleh amenore. Perbaikan pola mentruasi terjadi pada pasien yang mendapatkan anti-tuberkulosis.Discrepancy of Pre Operative Diagnosis and Post Operative Pathology Result of Genital Tuberculosis and Related Menstruation AbnormalitiesAbstractObjective: To evaluate the discrepancy between preoperative diagnosis and postoperative histopathological results in genital tuberculosis cases and evaluate the related changes of menstrual pattern. Methods: This was a descriptive study with cross-sectional approach to patients diagnosed with genital tuberculosis based on histopathological examination. Study population was taken from medical records of patients diagnosed with genital tuberculosis based on ICD 10 from January 2017 to June 2021. Total sampling method was used, with determined inclusion and exclusion criteria. Preoperative diagnosis was compared with postoperative histopathological results. Patients with histopathological result of genital tuberculosis were then interviewed via call to determine menstrual disorder patterns according to FIGO 2018 criteria.Results: There were 11 patients included in this study. Discrepancy in preoperative diagnosis and histopathological restult was found in 6 patients (54.55%). Menstrual disorders in the form of amenorrhea and oligomenorrhea were found in genital tuberculosis patients. Six-month first line tuberculosis therapy regimen was given to 3 out of 5 patients with confirmed genital tuberculosis.Conclusion: There is a large discrepancy between preoperative diagnosis and postoperative histopathological result of genital tuberculosis. This discrepancy impacted postoperative treatment options and delayed adequate tuberculosis therapy. Oligomenorrhea, followed by amenorrhea are the two main menstrual disorders in tuberculosis. Improvements in menstrual pattern were found in patients receiving complete anti-tuberculosis therapy. Key words: Uterine bleeding, Diagnostic discrepancy, Genital tuberculosis, Treatment of genital tuberculosis
Gambaran Karakteristik Klinis dan Histopatologi Kanker Ovarium Anak di RSUP Dr. Hasan Sadikin Bandung
Get PDFTujuan: Untuk mengetahui gambaran karakteristik klinis dan histopatologi kanker ovarium anak di RSUP Dr. Hasan Sadikin Bandung.Metode: Penelitian ini menggunakan desain penelitian deskriptif. Data dikumpulkan dari rekam medis pasien kanker ovarium anak di RSUP Dr. Hasan Sadikin Bandung tahun 2017–2020.Hasil: Terdapat 22 pasien kanker ovarium anak yang sesuai dengan kriteria inklusi dan eksklusi. Ditemukan pasien kanker ovarium anak paling banyak usia 13–18 tahun sebanyak 13 orang (59,1%), stadium klinis I sebanyak 10 orang (45,4%), histopatologi jenis sel germinal sebanyak 17 orang (77%), dan gejala klinis benjolan pada perut sebanyak 16 orang (33%).Kesimpulan: Kanker ovarium anak di RSUP Dr. Hasan Sadikin Bandung Bandung periode 1 Januari 2017 – 31 Desember 2020 paling sering terjadi pada pasien dengan rentang usia 13–18 tahun, terdiagnosis pada stadium I, karakteristik histopatologi tipe sel germinal, dan memiliki gejala klinis berupa benjolan pada perut.Overview of Clinical Characteristics and Histopathology of Pediatric Ovarian Cancer at RSUP Dr. Hasan Sadikin Bandung AbstractObjective: To determine pediatric ovarian cancer’s clinical characteristics and histopathology at RSUP Dr. Hasan Sadikin Bandung.Methods: This study used a descriptive research design. Data were collected from medical records of pediatric ovarian cancer patients at RSUP Dr. Hasan Sadikin Bandung in 2017 – 2020.Result: 22 pediatric ovarian cancer patients met the inclusion and exclusion criteria. The majority of pediatric ovarian cancer patients were 13-18 years as many as 13 people (59.1%), clinical stage I as many as 10 people (45.4%), histopathological germ cell types as many as 17 people (77%), and clinical symptoms as lumps in the abdomen as many as 16 people (33%).Conclusion: Pediatric ovarian cancer at RSUP Dr. Hasan Sadikin Bandung period 1 January 2017 – 31 December 2020 most occurred in patients aged 13–18 years, diagnosed at stage I, histopathological characteristics of germ cell type, and had clinical symptoms in the form of abdominal lump.Key words: Ovary, Pediatric Ovarian Cancer, Clinical Characteristic, Histopathological Characteristi
Profil Penderita Kanker Endometrium di RSUP Dr. Hasan Sadikin Bandung Periode Tahun 2017-2020
Get PDFTujuan: Mengetahui profil penderita kanker endometrium.Metode: Penelitian metode deskriptif dengan menggunakan data sekunder. Kriteria inklusi penelitian yaitu pasien dengan diagnosis kanker endometrium dilihat berdasarkan hasil histopatologi.Hasil: Distribusi pasien mayoritas berusia >50 tahun (62,0%), berasal dari Kota/Kabupaten Bandung (32,5%), memiliki indeks massa tubuh 18,5-22,9 kg/m2 (27,0%), multipara (36,5%), status postmenopause (59,0%), memiliki usia menarche ≥12 tahun (88,0%), tidak memiliki riwayat diabetes mellitus (66,0%) dan hipertensi (27,0%), terdiagnosis ketika stadium I (47,5%), dengan derajat diferensiasi baik/grade I (31,0%) dan tipe I endometrioid adenocarcinoma (82,5%). Terapi yang paling sering adalah tindakan operasi (50,0%) dengan tipe pembedahan histerektomi total dan salfingooforektomi bilateral (44,21%).Kesimpulan: Pasien kanker endometrium di RSUP Dr. Hasan Sadikin Bandung periode tahun 2017-2020 ditemukan paling banyak berusia >50 tahun, dari Kota/Kabupaten Bandung, indeks massa tubuh normal, multipara, postmenopause, usia menarche ≥12 tahun, tidak ada riwayat DM dan hipertensi, terdiagnosis pada stadium I dengan tipe I endometrioid adenocarcinoma dan derajat diferensiasi baik (grade I), serta dilakukan tindakan operasi dengan tipe pembedahan histerektomi total dan salfingooforektomi bilateral.Profile of Endometrial Cancer Patients in Dr. Hasan Sadikin Central General Hospital Bandung in 2017–2020AbstractObjective: Identifying the profile of endometrial cancer patientsMethods: This research used descriptive method by collecting secondary data. The inclusion criteria was patients with endometrial cancer diagnosis based on the histopathological results.Results: In this research, the majority of patients were aged >50 years (62,0%), came from Bandung City/Regency (32,5%), with body mass index of 18,5-22,9 kg/m2 (27,0%), multiparous (36,5%), postmenopause (59,0%), menarcge age of ≥12 years (88,0%), no history of diabetes mellitus (66,0%) and hypertension (27,0%), diagnosed at stage I (47,5%), with histopathological results well differentiated/grade I (31,0%) and type I endometrioid adenocarcinoma (82,5%). Surgery (50,0%) with the type of total hysterectomy and bilateral salpingoophorectomy (44,21%) was the most common treatment.Conclusion: In 2017-2020, endometrial cancer patient in Dr. Hasan Sadikin Central General Hospital Bandung were mostly found in the aged of >50 years, came from Bandung City/Regency, normal body mass index, multiparous, postmenopause, menarche age of ≥12 years, no history of diabetes mellitus and hypertension, diagnosed at stage I with histopathological result type I endometrioid adenocarcinoma and well differentiated (grade I), and the treatment was surgery with the type of total hysterectomy and bilateral salpingoophorectomy.Key words: Endometrial cancer, profile, risk facto
Absolute Lymphocyte Count and Neutrophil Lymphocyte Ratio in Pregnancy Confirmed Positive for SARS-CoV-2 at Dr. M. Djamil Hospital, Padang
Get PDFObjective: To determine the description of ALC and NLR in pregnant women who were confirmed positive for SARS-CoV-2 at Dr. M. Djamil Padang Hospital.Methods: A descriptive study in pregnancy was confirmed positive for COVID-19 on March 2020 to February 2021 at Dr. M. Djamil Padang Hospital.Results: 126 cases of pregnant women with COVID-19 with 25 (20%) patients experiencing a decrease in ALC less than 1500/µL and 101 (80%) patients had ALC values ≥ 1500/µL. NLR values were found to be increased by ≥3.13 in 91(72%) patients and <3.13 in 35(28%) patients. Conclusion: Most patients’ ALC values were normal, while the NLR values were mainly elevated.Gambaran Absolute Lymphocyte Count dan Neutrophil Lymphocyte Ratio pada Wanita Hamil yang Terkonfirmasi Positif SARS-Cov2 di RSUP Dr. M. Djamil, Padang AbstrakTujuan: Untuk mengetahui gambaran ALC dan NLR pada ibu hamil yang terkonfirmasi positif SARS-CoV-2 di RSUP Dr. M. Djamil Padang.Metode: Studi deskriptif pada kehamilan terkonfirmasi positif COVID-19 selama Maret 2020 hingga Februari 2021 di RS Dr. M. Djamil Padang.Hasil: 126 kasus ibu hamil dengan COVID-19 dengan 25 (20%) pasien mengalami penurunan ALC yaitu kurang dari 1500/µL dan 101 (80%) pasien memiliki nilai ALC 1500/µL. Nilai NLR ditemukan meningkat 3.13 pada 91 (72%) pasien dan <3.13 pada 35 (28%) pasien.Kesimpulan: Nilai ALC ditemukan normal pada sebagian besar pasien, sedangkan nilai NLR ditemukan sebagian besar meningkat.Kata kunci: kehamilan, COVID-19, Absolute Lymphocyte Count, Neutrophil Lymphocyte Rati
Hubungan Kadar Trombosit dan Neutrofil antara Kanker Ovarium Tipe Epitelial Rekuren dan Nonrekuren
Get PDFTujuan: Menganalisis hubungan kadar trombosit dan neutrofil terhadap rekurensi kanker ovarium.Metode: Penelitian observasi case control. Data dan sampel darah diambil dari perempuan penderita kanker ovarium tipe epitelial rekuren dan tidak rekuren sebanyak 117 orang. Data yang diambil berupa usia, paritas, status menopause, serta hasil laboratorium darah rutin saat sebelum kemoterapi dan pasca kemoterapi 6 kali. Data diuji dengan analisis independent sample t test, uji Mann Whitney, analisis korelasi, serta analisis regresi logistik biner.Hasil: Terdapat hubungan yang signifikan antara kadar trombosit dan neutrofil terhadap rekurensi kanker ovarium (p0,05).Kesimpulan: Kadar trombosit dan netrofil memiliki korelasi terhadap rekurensi kanker ovarium. Kadar leukosit dan hemoglobin tidak berkaitan dengan rekurensi kanker ovarium.Correlation between Platelet and Neutrophil Levels in Recurrence Epithelial Ovarian CancerAbstractObjective: To analyze the relationship between platelet and neutrophil levels on ovarian cancer recurrenceMethods: Case-control observation research. Data and blood samples were taken from 117 women with recurrent and non-recurrent epithelial ovarian cancer patients. Primary data taken were age, parity, menopausal status, laboratory results of routine blood examination carried out before and after chemotherapy six times. Data were tested by independent sample t-test, Mann Whitney test, correlation analysis, and binary logistic regression analysis.Results: There was a statistically significant relationship between platelets and neutrophils with ovarian cancer recurrence (p0.05).Conclusion: Platelet and neutrophil levels are associated with ovarian cancer recurrence. Leukocyte and hemoglobin levels were not associated with ovarian cancer recurrence.Key words: ovarian cancer, chemotherapy, recurrence, platelet
Purandare Hysteropexy in A 32 Years Old Woman with Stage III Pelvic Organ Prolapse and Cesarean History: Case Report
No full textBackground: In reproductive age and low-parity women, pelvic organ prolapse is an uncommon case. Although this condition isn’t harmful, giving an appropriate treatment is important while considering women needs. This case report covers about the management of Purandare hysteropexy in a 32 years old woman with stage III pelvic organ prolapse and cesarean section history.Case: Conservative surgical therapy, Purandare hysteropexy, was performed on a reproductive age woman with stage III pelvic organ prolapse who wish to conserve her uterus.Result: Purandare hysteropexy was successfully performed on the patient, and she has better quality of life and minimal complaint after surgery.Conclusion: Purandare hysteropexy is an appropriate conservative surgical therapy, comparable to mesh using surgery, for women of reproductive age with pelvic organ prolapse.Histeropexi Purandare pada Wanita Usia 32 Tahun dengan Prolaps Organ Panggul Derajat III dan Riwayat Seksio Cesarea: Laporan KasusAbstrakLatar Belakang: Prolaps organ panggul adalah kasus yang jarang terjadi pada wanita usia reproduktif atau riwayat paritas rendah. Walaupun kondisi ini tidak berbahaya, terapi yang diberikan harus sesuai dengan keperluan dari wanita. Laporan kasus ini menggambarkan proses manajemen histeropexi purandare pada wanita usia 32 tahun dengan prolaps organ panggul wanita derajat III dan riwayat seksio cesarea. Kasus: Terapi bedah konservatif, histeropexi purandare, dilakukan pada wanita usia reproduktif dengan prolaps organ panggul derajat III yang masih ingin mempertahankan uterusnya. Hasil: Purandare histeropeksi berhasil dilakukan pada pasien. Pasien mempunyai kualitas hidup dan keluhan yang minimal setelah prolaps organ panggul Kesimpulan: Histeropexi Purandare adalah terapi bedah konservatif, yang sesuai, setara dengan pembedahan yang menggunakan mesh, untuk dilakukan pada wanita usia reproduktif dengan prolaps organ panggul. Kata kunci: prolaps organ panggul, wanita usia reproduktif, purandare, histeropexi