OBGYNIA - Indonesian Journal of Obstetrics & Gynecology Science
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    Pola Kuman dan Kepekaan Antibiotik pada Kasus Infeksi Luka Operasi Obstetri

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    Tujuan: Mengetahui karakteristik pasien infeksi luka operasi (ILO) bidang Obstetri dan mendeskripsikan gambaran pola kuman serta kepekaan antibiotiknya di Rumah Sakit Umum Pusat (RSUP) Dr. Hasan Sadikin BandungMetode: Penelitian ini merupakan penelitian deskriptif observasional dengan pendekatan cross sectional yang bersifat retrospektif dari rekam medis pasien obstetri yang terdiagnosis infeksi luka operasi di RSUP Dr. Hasan Sadikin Bandung selama periode Juli 2020 - Juni 2021. Karakteristik subjek meliputi usia, berat badan, tinggi badan, body mass index (BMI),  dan paritas. Dalam penelitian ini digunakan tingkat ketelitian (α) 5%, tingkat kepercayaan 95% sehingga diperoleh nilai Z = 1,96. Deskripsi karakteristik dan status pasien ditampilkan dalam bentuk tabel. Data kategorik dideskripsikan dengan jumlah (n) dan persentase (%).Hasil: Hasil penelusuran rekam medis didapatkan sebanyak 20 pasien yang didiagnosis dengan ILO. Seluruh pasien yang mengalami ILO merupakan pasien pasca  seksio sesarea. Tidak didapatkan perbedaan yang bermakna pada rerata umur, berat badan, tinggi badan, BMI, dan sebaran paritas. Kesimpulan: ILO pada bidang obstetri seluruhnya terjadi pasca seksio sesarea. Tidak didapatkan perbedaan bermakna pada karakteristik pasien yang mengalami ILO. Pola kuman yang paling sering dijumpai adalah Escherichia coli dan Acinetobacter baumannii. Antibiotik yang sensitif terhadap mayoritas sampel adalah tigecycline dan meropenem.Antibiotic Susceptibility and Microbial Pattern in Obstetric Surgrical Wound InfectionAbstractObjective: To know the characteristics of surgical site infection (SSI) patients  in obstetrics field and describing the microbial pattern and their antibiotic sensitivity at the Hasan Sadikin General HospitalMethod: This study was a descriptive observational study with a retrospective cross sectional approach from the medical records of obstetric patients diagnosed with surgical wound infections at Dr. Hasan Sadikin Bandung during the period July 2020 - June 2021. Subject characteristics include age, weight, height, body mass index (BMI), and parity. In this study, the level of accuracy (α) 5%, 95% confidence level, so that the value of Z = 1.96 is obtained. Results: The results gained from tracing medical records and obtained as many as 20 patients diagnosed with SSI. All patients who experienced SSI were post-cesarean section patients. There were no significant differences in the mean age, weight, height, BMI, and parity distribution. Conclusion: There was a high prevalence of female sexual dysfunction among health practitioners at Hasan Sadikin General Hospital, accounting to 41.8%. There was no statistically significant difference between various demographic aspects and female sexual dysfunction. Key words: Microbial pattern, antibiotic, sensitivity, surgical site infectio

    Cervical Cancer Radiotherapy Response in Dr. Hasan Sadikin General Center Hospital

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    Objective: To determine the response to radiation therapy based on the characteristics of cervical cancer patients who were given radiotherapy at Hasan Sadikin Hospital in 2020.Methods: The study was conducted using an observational analytic study method with a cross-sectional design, involving 75 cases of cervical carcinoma who were given complete radiation therapy but were not given neoadjuvant chemotherapy or surgery, which were recorded in the medical record at the Central General Hospital (RSUP) Dr. Hasan Sadikin. Results: Response to therapy had a significant relationship (p< 0.05) with age (p 0.030), histopathological type (p 0.009), and tumor mass size (p 0.042), but had no significant relationship to cervical cancer stage (p 0.055). Further analysis found that the response to radiation therapy at stage III was highly dependent on the size of the tumor mass (p<0.001). Based on the odds ratio calculation, the response to therapy was better in patients aged 35 years 3.44 times compared to patients aged 18-34 years, cervical cancer with squamous type histopathology 5.23 times compared to adenocarcinoma type histopathology, and cervical cancer with tumor mass size. <4 cm 2.86 times compared to tumor mass size 4 cm.Conclusion: The therapeutic response was better in cervical cancer patients who underwent complete radiation therapy in patients aged 35 years, stage III cervical cancer with tumor mass size <4 cm, squamous type histopathology, and tumor mass size <4cm.Respon Radioterapi pada Kanker Serviks di Rumah Sakit Umum Pusat Dr. Hasan Sadikin BandungAbstrakTujuan: Untuk mengetahui respon terapi radiasi berdasarkan karakteristik pasien kanker serviks yang diberikan radioterapi di Rumah Sakit Hasan Sadikin tahun 2020. Metode: Penelitian dilakukan menggunakan metode studi analitik observasional dengan desain potong lintang, melibatkan 75 kasus karsinoma serviks yang diberikan terapi radiasi komplit tetapi tidak diberikan kemoterapi neoadjuvant maupun tindakan operasi, yang tercatat pada rekam medis di Rumah Sakit Umum Pusat Dr. Hasan Sadikin.Hasil: Respon terapi memiliki hubungan yang signifikan (p<0,05) terhadap usia (p 0,030), tipe histopatologi (p 0,009), dan ukuran massa (p 0,042), tetapi memiliki hubungan yang tidak bermakna terhadap stadium kanker serviks (p 0,055). Analisis lebih lanjut didapatkan bahwa respon terapi radiasi pada stadium III sangat bergantung kepada ukuran massa tumor (p<0,001). Berdasarkan penghitungan odd ratio respon terapi lebih baik didapatkan pada pasien berusia ≥35 tahun 3,44 kali dibandingkan pada usia 18-34 tahun, kanker serviks dengan histopatologi tipe skuamosa 5,23 kali dibandingkan histopatologi tipe adenokarsinoma, dan kanker serviks dengan ukuran massa tumor <4 cm 2,86 kali dibandingkan ukuran massa tumor ≥4 cm.Kesimpulan: Respon terapi lebih baik pada pasien kanker serviks yang dilakukan terapi radiasi komplit pada pasien berusia ≥ 35 tahun, kanker serviks stadium III dengan ukuran massa tumor <4 cm, histopatologi tipe skuamosa, dan ukuran massa tumor <4cm.Kata kunci : respon terapi, radiasi, kanker servik

    Tiga Kasus Holoprosensefal Alobar dengan Variasi Gambaran Klinis:Diagnosis Ultrasonografi

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    Holoprosensefal (HPE) adalah spektrum malformasi dengan berbagai hasil luaran. Laporan ini menjelaskan 3 kasus holoprosensefal alobar yang dikonfirmasi saat antenatal dengan pemeriksaan ultrasonografi (USG). Selain gambaran holoprosensefal alobar yang serupa pada ketiga kasus, ditemukan gambaran lain yaitu probosis, siklops, kelainan jantung, dan arteri umbilikalis tunggal. Gambaran klinis yang berbeda adalah preeklamsia, polidaktili, dan mikropenis pada kasus pertama, pada kasus kedua adalah mielomeningokel; dan hidransefal untuk kasus ketiga. Analisis kromosom dilakukan hanya pada kasus kedua dengan hasil berupa translokasi kromosom 3 ke 9 (46 XX, der (9) t(3:9)(p21:q33). Pencitraan menggunakan USG adalah modalitas yang bermanfaat untuk mendeteksi holoprosensefal alobar. Bila skrining dilakukan pada masa usia kehamilan yang tepat maka dapat ditemukan kelainan kongenital mayor letal secara dini, sehingga terminasi kehamilan lebih mudah dengan komplikasi yang lebih minimal.Three Cases Of Holoprosencephalic Alobar With A Variety Of Clinical Features: Ultrasound DiagnosticAbstractHoloprosencephaly (HPE) is a spectrum of malformations with various outcomes and the most common congenital brain disorder. This report describes 3 cases of alobar holoprosencephaly that were confirmed antenatally by ultrasound examination. Apart from the similar appearance of alobar holoprosencephaly in all three cases, other similar characteristics were proboscis, cyclopia, heart defects, and a single umbilical artery. The different clinical features were maternal preeclampsia, polydactyly, and micropenis in the first case. The different clinical feature in the second case was myelomeningocele; and hydranencephaly for the third case. Chromosome analysis was performed only in the second case with results in the form of translocation of chromosomes 3 to 9 (46 XX, der (9) t(3: 9)(p21: q33).If the chromosome analysis is limited, ultrasound imaging is beneficial for detecting alobar holoprosencephaly.Key words: alobar holoprosencephaly, myelomeningocele, hydranencephaly, preeclampsi

    Perbedaan Capaian Kontrasepsi Pascasalin Jangka Panjang Sebelum dan Saat Pandemi Covid-19

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    Tujuan: Mengetahui perbedaan capaian kontrasepsi pascasalin jangka panjang sebelum dan saat pandemi COVID-19 di RSUP dr. Hasan Sadikin Bandung. Metode: Penelitian ini adalah studi analitik observasional dengan pendekatan potong silang menggunakan data sekunder dari rekam medik subjek penelitian selama masa pengamatan yakni sebelum pandemi (1 Maret 2019–28 Februari 2020) dan saat pandemi (1 Maret 2020–28 Februari 2021). Dilakukan analisis perbedaan capaian kontrasepsi pascasalin jangka panjang sebelum dan saat pandemi COVID-19, serta perbedaan capaian penggunaan kontrasepsi pascasalin jangka panjang berdasarkan status infeksi COVID-19 menggunakan uji chi-square. Nilai P <0,05 dianggap bermakna secara statistik.Hasil: Selama periode pengamatan didapatkan proporsi subjek yang mendapatkan layanan kontrasepsi pascasalin pada periode pandemi lebih tinggi secara bermakna dibandingkan dengan kelompok sebelum pandemi (38,8% vs 27,7%, P<0,001). Tidak didapatkan perbedaan bermakna sebaran penggunaan metode kontrasepsi pada kelompok saat pandemi yang terinfeksi dan tidak terinfeksi COVID-19.Kesimpulan: Capaian pemberian kontrasepsi pascasalin jangka panjang saat pandemi lebih tinggi secara bermakna dibandingkan dengan sebelum pandemi. Tidak didapatkan perbedaan yang bermakna capaian kontrasepsi pascasalin jangka panjang saat pandemi pada subjek yang terinfeksi dan tidak terinfeksi COVID-19.Differences in Long-Term Postpartum Contraception Achievements Before and During The Covid-19 PandemicAbstractObjective: To find out the difference in the achievement of long-term postpartum contraception before and during the COVID-19 pandemic at dr. Hasan Sadikin Bandung.Methods: This research is an observational analytic study with a cross-sectional approach using secondary data from the medical records of the research subjects during the observation period before the pandemic (1 March 2019–28 February 2020) and during the pandemic (1 March 2020–28 February 2021). An analysis of the difference in the achievement of long-term postpartum contraception before and during the COVID-19 also differences in achievement of long-term postpartum contraceptive use was carried out based on the status of COVID-19 infection was conducted using the chi-square test. P-value < 0.05 was considered statistically significant.Results: During the observation period, there were the proportion of subjects who received postpartum contraceptive services during the pandemic period was significantly higher than the group before the pandemic (38.8% vs 27.7%, P<0.001). Postpartum contraceptive use in the group during the pandemic infected with COVID-19 was lower than in the uninfected subjects (32.4% vs. 39.4%, P=0.07). There was no significant difference in the distribution of contraceptive methods used in the infected and uninfected groups during the COVID-19 pandemic.Conclusion: The achievement of long-term postpartum contraception during the pandemic was significantly higher than before the pandemic. There was no significant difference in the achievement of long-term postpartum contraception during the pandemic in subjects who were infected and not infected with COVID-19.Key words: COVID-19, postpartum contraception, pandemic

    Defisiensi Mikronutrisi (Zat Besi, Magnesium, Zinc, Kalsium, Vitamin D, Asam Folat, Vitamin C, Vitamin E, dan Omega 3) pada Preeklamsia

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    Preeklamsia masih menjadi penyebab utama mortalitas dan morbiditas maternal neonatal di Indonesia. Preeklamsia disebabkan oleh multifaktorial yang ujungnya akan berakhir dengan terjadinya disfungsi endotel vaskular dan manifestasi klinis sistemik. Indonesia merupakan salah satu negara berkembang dengan masalah besar yang terkait dengan nutrisi. Tingginya angka stunting dan malnutrisi pada anak-anak, remaja, dan ibu hamil merupakan masalah nasional yang menjadi perhatian utama. Defisiensi nutrisi khususnya mikronutrisi ditunjukkan dari berbagai penelitian memiliki kaitan dengan terjadinya hipertensi dalam kehamilan. Pada artikel ini kami akan membahas mengenai peran dan keterkaitan mikronutrisi (Zat besi, magnesium, zinc, kalsium, vitamin C, D, E, dan DHA) dengan terjadinya preeklamsia. AbstractIn Indonesia, preeclampsia continues to be the leading cause of maternal and infant morbidity and mortality. A complex etiology for preeclampsia led to vascular endothelial dysfunction and a widespread clinical presentation. Indonesia is a developing nation with significant nutrition-related issues. The key cause for concern is the high rate of stunting and malnutrition in children, adolescents, and pregnant women. Micronutrient deficits in particular have been linked to the development of hypertensive disorders in pregnancy. In this post, we will discuss about how micronutrients like iron, magnesium, zinc, calcium, and the vitamins C, D, E, and DHA might affect in the development of preeclampsia

    Hubungan Karakteristik Maternal dan Luaran Neonatus Kasus Ketuban Pecah Dini di RSUP Dr. Hasan Sadikin Bandung: Studi Kasus-Kontrol

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    Tujuan: Penelitian ini bertujuan untuk mengetahui hubungan antara ketuban pecah dini (KPD) dengan karakteristik ibu dan luaran neonatal di RSUP Dr. Hasan Sadikin Bandung pada tahun 2019.Metode: Penelitian ini merupakan penelitian observasional analitik dengan desain case control. Subjek penelitian adalah seluruh kasus persalinan pervaginam dan seksio sesarea tahun 2019 di RSUP Dr. Hasan Sadikin Bandung.Hasil: Pada penelitian ini diperoleh subjek sebanyak 60 wanita yang terdiri dari 30 wanita dengan KPD dan 30 wanita tanpa KPD. Subjek penelitian sebagian besar dari kelompok usia 20-35 tahun. Tidak ada perbedaan yang signifikan dari usia ibu antara kelompok KPD dan kelompok kontrol (P = 0,774). Kelompok KPD memiliki proporsi wanita primipara yang lebih tinggi secara signifikan (70%), dibandingkan dengan kelompok kontrol (36,67%), dengan P = 0,010. Kelompok KPD memiliki proporsi kehamilan prematur lebih tinggi (63,33%), dibandingkan dengan kelompok kontrol (40%), tetapi tidak signifikan (p = 0,071). Ditemukan juga bahwa kelompok KPD sebagian besar (66,67%) berpendidikan rendah (SMP sederajat atau lebih rendah) dibandingkan dengan kelompok kontrol (36,67%) dengan P = 0,007.Kesimpulan: Temuan dalam penelitian ini menunjukkan bahwa status primipara dan tingkat pendidikan yang rendah berhubungan dengan kejadian KPD. Selain itu, KPD juga dikaitkan dengan jenis kelamin bayi laki-laki, berat badan lahir rendah, dan skor APGAR yang rendah.Maternal Characteristics and Neonatal Outcomes of Premature Rupture of Membranes Cases in a Tertiary Hospital in West Java: A Case-Control StudyAbstractObjective: This study aims to find an association between premature rupture of membranes (PROM) with maternal characteristics and neonatal outcomes in a tertiary hospital in West Java, Indonesia in 2019. Methods: This research is an analytic observational study with a case control design. The subjects were all cases of vaginal delivery and cesarean section in 2019 at a tertiary hospital in West Java, Indonesia.Results: In this study, a sample of 60 subjects was obtained, consisting of 30 subjects with PROM and 30 subjects without PROM. Subjects were mostly from the age group of 20-35 years. There was no significant difference of the maternal age between PROM and control groups (p-value = 0.774). The PROM group has a significantly higher incidence of primiparous women (70%), compared to the control group (36.67%), with a p-value of 0.010. The PROM group has a higher percentage of preterm gestation (63.33%), compared with the control group (40%), but was not significant (p = 0.071). It was also found that the PROM group were mostly (66,67%) from the lower level of education (middle school or lower) compared with the control group (36,67%) with a p-value of 0.007.Conclusion: The findings in this study showed that primiparity and low education levels are associated with the incidence of PROM. In addition, PROM is also associated with male newborn, low birth weight, and low APGAR scores.Key words: Neonatal outcomes, premature rupture of membranes

    Relationship of Age, Body Mass Index, Gravida, and Parity in Pregnant Women with the Incidence Preeclampsia

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    AbstractObjective: According to the 2016 Routine Health Profile Report, the exact causes of maternal mortality are hypertension (33.07%) and bleeding (27%). The exact cause of preeclampsia is unknown and is therefore referred to as the “disease of theory”. This study aimed to determine the relationship between age, BMI, gravida and parity with preeclampsia.Methods: This cross-sectional, analytic observational study, conducted in Hasan Sadikin Hospital, Bandung. Subjects are pregnant women undergoing antenatal care at Hasan Sadikin Hospital Bandung, in May 2020 a total of 40 women with a gestational age of  ≥ 20 weeks. The univariate and bivariate data were analyzed with SPSS. The Saphiro Wilk test was used to measure the data normality. The ANOVA one-way test and Fisher test were used to analyze the bivariate data.Results: Results show that of 19 samples with preeclampsia, 13 people (68.4%) were older than 35 years old with p-value of 0.042 which indicates a significant relationship. There is no significant difference between BMI, gravida, and parity, with the incidence of preeclampsia with p-value 0.602, 0.664, and 0.661 respectively.Conclusion: There is a relationship between mother’s age and the incidence of preeclampsia in Dr. Hasan Sadikin Hospital with p value = 0.042. This means older than 35 years old mothers have a tendency to develop preeclampsia.Hubungan Usia, Indeks Massa Tubuh, Gravida, dan Paritas pada Ibu Hamil dengan Insidensi PreeklamsiaAbstrakTujuan: Penelitian ini bertujuan untuk mengetahui hubungan paritas dengan preeklamsia.Metode: Studi observasional analitik potong lintang ini dilakukan di Rumah Sakit Hasan Sadikin Bandung. Subjek adalah ibu hamil yang menjalani pemeriksaan kehamilan di RS Hasan Sadikin Bandung, pada bulan Mei 2020 sejumlah 40 orang dengan usia kehamilan ≥ 20 minggu. Data univariat dan bivariat dianalisis dengan SPSS. Uji Saphiro Wilk digunakan untuk mengukur normalitas data. Uji satu arah ANOVA dan uji Fisher digunakan untuk menganalisis data bivariat.Hasil: Hasil penelitian menunjukkan bahwa dari 19 sampel dengan preeklamsia, 13 orang (68,4%) berusia lebih dari 35 tahun dengan p-value 0,042 yang menunjukkan hubungan yang signifikan.Kesimpulan: Ada hubungan usia ibu dengan kejadian preeklampsia di RSUD Dr. Hasan Sadikin dengan nilai p = 0,042. Ini berarti ibu yang berusia lebih dari 35 tahun memiliki kecenderungan untuk mengalami preeklamsia.Kata kunci: Preeklamsia, usia, IMT, gravida, parita

    Hubungan Antara Rasio Neutrofil-Limfosit Terhadap Kejadian Metastasis Intraperitoneal pada Pasien Karsinoma Musinosum Ovari di RSUD Prof. Dr. Margono Soekarjo Tahun 2017-2020

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    Tujuan: Untuk mengetahui hubungan antara rasio neutrofil-limfosit terhadap kejadian metastasis intraperitoneal pada pasien karsinoma musinosum ovari di RSUD Prof Dr. Margono SoekarjoMetode: Penelitian analitik observasional dengan desain cross-sectional dilakukan pada 43 pasien karsinoma musinosum ovari. Data diambil melalui rekam medis pemeriksaan laboratorium berupa neutrofil dan limfosit pre-operasi pertama tahun 2017-2020. Teknik pengambilan data menggunakan consecutive sampling. Data dianalisis secara statistik dengan uji chi-squareHasil: Penelitian menunjukkan bahwa dari 43 pasien, didapatkan rerata usia pasien 51 tahun, mayoritas stadium IIIB (25%). Rasio Neutrofil Limfosit katagori rendah ≤ 4,1 (30%), Rasio Neutrofil Limfosit  katagori tinggi >4,1 (70%) serta rerata Rasio Neutrofil Limfosit 10.74. Nilai Rasio Neutrofil Limfosit pada pasien yang mengalami metastasis cenderung lebih tinggi daripada pasien yang tidak mengalami metastasis. Lokasi metastasis karsinoma musinosum sebagian besar pada rongga pelvis. Analisis hubungan antara Rasio Neutrofil Limfosit dengan metastasis intraperitoneal secara statistik menunjukan (CI:0.22-9.12,p = 0,000; p ≤ 0,05).Kesimpulan: Terdapat hubungan antara rasio neutrofil-limfosit terhadap kejadian metastasis intraperitoneal pada karsinoma musinosum ovari.Correlation between Neutrophil Lymphocytes Ratio With Metastases Intraperitoneal Of Mucinous Ovary Cancer in Hospital Prof Dr Margono Soekarjo 2017-2020Abstract Objective: Purpose to determine the correlation between Neutrophils-Lymphocytes Ratio (NLR) with the metastases intraperitoneal of mucinous ovarian cancer patients in RSUD Prof Dr. Margono Soekarjo.Method: This study uses observational analytic method with cross-sectional design. The subjects of this study were 43 patients with mucinous ovary cancer which data neutrophil and lymphocytes pre one surgery. The data source comes from secondary data taken from the medical record installation in the period 2017-2020 using consecutive sampling technique.Results: This study showed that from 43 patients , the mean were aged 51 years. The majority were stage IIIB (25%). Neutrophil Lymphocyte Ratio low category ≤4.1 (30%), Neutrophil Lymphocyte Ratio high category >4.1 (70%) and the mean Neutrophil Lymphocyte Ratio 10.74. The location of mucinous carcinoma metastases is mostly in the pelvic cavity. Analysis of the correlation between NLR with metastases intraperitoneal showed that statistically (CI:0.22-9.12,p = 0,000; p ≤ 0,05).Conclusion: There is correlation between Neutrophils-Lymphocytes Ratio (NLR) with the metastases intraperitoneal of mucinous ovarian cancer.Key words: carsinoma mucinous ovary cancer,neutrophil-lymphocyte ratio (NLR),metastases intraperitonea

    Korelasi Asupan Vitamin C dan vitamin D dengan Kadar Timbal Ibu Hamil Preeklamsia

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    Tujuan: Untuk mengetahui korelasi asupan vitamin C dan vitamin D dengan kadar timbal ibu hamil preeklampsia.Metode: Studi analitik korelatif dengan pendekatan cross sectional. Sampel penelitian ini yaitu 33 orang ibu hamil preeklampsia bertempat tinggal radius ≤10 km, dan 33 orang ibu hamil preeklampsia bertempat tinggal radius >10 km dari PT. Semen Padang. Penelitian dilakukan di RSUD Rasidin, RSPTM Unand, RS. Hermina, RS. Tentara Reksodiwiryo, RS. Ibnu Sina, dan RSUP Dr. M. Djamil Padang pada bulan Mei 2021-Februari 2022. Hasil: Penelitian menunjukkan bahwa asupan vitamin C memiliki korelasi negatif yang sangat kuat dengan kadar timbal ibu hamil preeklamsia yang bertempat tinggal radius ≤10 km dari pabrik PT. Semen Padang (r=-0,872, p=0,000), sedangkan asupan vitamin C tidak berkorelasi dengan kadar timbal ibu hamil preeklamsia yang bertempat tinggal radius >10 km dari pabrik PT. Semen Padang (r=-0,049, p=0,785). Asupan vitamin D dengan kadar timbal ibu hamil preeklamsia yang bertempat tinggal radius ≤10 km dan >10 km dari pabrik PT. Semen Padang masing-masing memiliki korelasi negatif yang kuat dan sedang (r=- 0,696, r=-512, p=0,000, p=0,002).Kesimpulan: Terdapat korelasi asupan vitamin C dan vitamin D dengan kadar timbal ibu hamil preeklampsia setelah dikontrol variabel cofounding (radius tempat tinggal, status merokok, dan lingkungan tempat tinggal).Correlation of Vitamin C and Vitamin D Intake with Lead Levels in Pregnant Women with PreeclampsiaAbstract Objective: This study aims to determine the correlation between the intake of vitamin C and vitamin D with lead levels in  pregnant women with preeclampsia.Method: This research is a correlative analytic study with a cross-sectional. The sample of this study was 33 preeclampsia pregnant women living in a radius of ≤10 km, and 33 preeclampsia pregnant women residing in a radius of >10 km from PT. The research was conducted at Rasidin Hospital, RSPTM Unand, RS. Hermina, RS. Tentara Reksodiwiryo, RS. Ibnu Sina, and RSUP Dr. M. Djamil Padang in May 2021-February 2022. Results: Vitamin C intake has a very strong negative correlation with lead levels of preeclampsia pregnant women who live within a radius of ≤10 km from the Semen Padang Factory (r=-0.872, p=0.000), while vitamin C intake is not correlated with the lead levels of preeclampsia pregnant women who live in a radius of >10 km from the Semen Padang Factory (r=-0.049, p=0.785). Vitamin D intake with lead levels of preeclampsia pregnant women who live in a radius of ≤10 km and >10 km from the Semen Padang Factory each has a strong and moderate negative correlation (r=- 0.696, r=-512, p=0.000, p=0.002).Conclusion: There is a correlation between vitamin C and vitamin D intake and lead levels of preeclampsia in pregnant women after controlling for confounding variables (radius of residence, smoking status, and living environment).Key words : Lead, Vitamin C intake, Vitamin D intake, Preeclampsia

    Hubungan antara Obesitas dengan Faktor Luaran Bayi pada Preeklamsia Berat

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    Tujuan: Membandingkan luaran berat badan dan panjang badan lahir bayi serta lama perawatan antara kelompok obesitas dan tidak obesitas pada penderita preeklamsia berat.   Metode: Desain penelitian menggunakan metode cohort retrospective dengan menggunakan data sekunder berupa rekam medis. Populasi penelitian adalah ibu hamil penderita preeklamsia berat yang melahirkan di Rumah Sakit Umum Pusat Dr. Hasan Sadikin pada periode 1 Januari 2015 – 31 Desember 2019, dengan teknik pengambilan sampel purposive dan didapatkan total 86 sampel.Hasil: Nilai rata-rata berat lahir kelompok obesitas secara signifikan (P 0.00) lebih berat 908.13 gram dibandingkan kelompok tidak obesitas (95% CI 513.81;1302.46 gram) dan nilai rata-rata panjang badan kelompok obesitas secara signifikan (P 0.00) lebih panjang 4.23 cm  dibandingkan kelompok tidak obesitas (95% CI 1.49;6.48 cm).  Nilai tengah lama perawatan kedua kelompok tidak menunjukkan perbedaan signifikan (P 0.48) dimana pada kelompok tidak obesitas, lama perawatan 4 hari sedangkan kelompok obesitas 5 hari. Kesimpulan:  Terdapat perbedaan yang signifikan secara statistik terhadap luaran bayi berupa berat lahir dan panjang badan lahir bayi antara kelompok obesitas dan tidak obesitas pada penderita preeklamsia berat, namun tidak terdapat perbedaan yang signifikan secara statistik terhadap lama perawatan antara kelompok obesitas dan tidak obesitas pada penderita preeklamsia berat.Comparison of Neonatal Outcomes and Length of Stay Based on Obesity Status in Severe PreeclampsiaAbstractObjective: To compare the outcome of neonatal birth weight and length as well as the length of stay between the obese and non-obese groups in patients with severe preeclampsia.Methods: This study used a retrospective cohort method and secondary data from medical record.. The population in this was 2055 pregnant women with severe preeclampsia who gave birth at the General Hospital Dr. Hasan Sadikin period January 1st, 2015 to December 31st, 2019.  The sample in this study uses purposive sampling method and the total sample is 86 samples. Result: The results showed that the mean birth weight of the obese group was significantly (P 0.00) heavier 908.13 grams compared to the non-obese group (95% CI 513.81; 1302.46 grams) and the mean birth length of the obese group was significantly (P 0.00) longer 4.23 cm compared to the non-obese group (95% CI 1.49; 6.48 cm). The median length of stay between the two groups did not show a significant difference (P 0.48), in the non-obese group, the length of stay was 4 days while the obese group was 5 days.Conclusion: There was a statistically significant difference in neonatal outcomes in terms of birth weight and birth length between the obese and non-obese groups in patients with severe preeclampsia, but there was no statistically significant difference in the length of stay between the obese and non-obese groups in patients with severe preeclampsia.Key word : Obesity, neonatal outcomes, length of stay, severe preeclampsi

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    OBGYNIA - Indonesian Journal of Obstetrics & Gynecology Science
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