Journals of Badan Penelitian dan Pengembangan Kesehatan
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Ekstrak Etanol Ubi Jalar Ungu untuk Mencegah Peningkatan pH Vagina setelah Ovariektomi Bilateral pada Tikus Wistar
Get PDFAVaginal atrophy is one of the most common health problems in postmenopausal women. The disease is characterized by decreasing layers and maturation index of the vaginal epithelium and an increase in vaginal pH. A decrease in vaginal acidity will increase the susceptibility to infections since acidic pH protects the vagina from pathogens infection. The previous study has proven that phytoestrogens were effective to improve the microstructures of the vaginal, reduce urogenital complaints, and improve vaginal pH. The purple sweet potato (Ipomea batatas L.) which is cultivated in Bali was recognized for its high anthocyanin content and was reported to have phytoestrogen activity. The aim of the present study is to evaluate the effect of purple sweet potato on vaginal pH in an animal model of menopause. The randomized pre-test post-test control group design study was conducted using 36 bilateral ovariectomized female Wistar rats as an animal model of menopause. The animals were divided randomly into a control group (T0) which was given saline and a treatment group (T1) given an ethanolic extract of purple sweet potato 400 mg/day for 30 days. Vaginal pH was measured before treatment, every week during treatment, and after treatment. The result of the study showed that there was an increase in vaginal pH of the T0 on the 2nd and 3rd week, and after treatment (
Isolasi dan Skrining Aktivitas Antibakteri Fungi Tanah Muara Desa Katialada Gorontalo Lokasi Satu terhadap Staphylococcus aureus
Get PDFThe emergence of antibiotic resistance becomes a barrier in controlling infectious diseases, so it is necessary to find new alternative antibiotics. This study aimed to explore the potential of estuarine soil fungals secondary metabolites isolated from Katialada Village Gorontalo Location One and test their antibacterial activity against Staphylococcus aureus. The antibacterial parameter observed was the percent inhibition of ethyl acetate extracts against Staphylococcus aureus. The estuarine soil samples were cultured in PDA media producing five single fungal isolates differentiated based on color morphology, texture, and shape coded IS2-BTG-4.1.1, IS2-BTG-4.1.2, IS1-BTG-4.2, IS2-BTG4.3.1, and IS2-BTG-4.3.2. Those five samples were fermented using PDB media and the fermented products were extracted with ethyl acetate. The extracts were screened for its compound using a TLC plate and antibacterial testing with a single concentration of 100 g/mL in the microdilution method. The screening results showed that the five ethyl acetate extracts contained terpenoid compounds and code IS2-BTG-4.3.2 also had alkaloids. Based on the antibacterial test results, the five ethyl acetate extracts had growth inhibitory activity on the Staphylococcus aureus, with the percentage showed by IS2-BTG-4.1.1 50,2% ± 14,8%, IS2-BTG-4.1.2 35,6% ± 12,9%, IS1-BTG-4.2 13,0% ± 7,3%, IS2-BTG-4.3.1 13,6% ± 6,0%, and IS2-BTG-4.3.2 by 12,4% ± 9,2%
Analisis Autokorelasi Spasial Kejadian Demam Berdarah Dengue (DBD) di Kabupaten Klaten Tahun 2020
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The cases of Dengue Hemorrhagic Fever (DHF) in Klaten Regency still increase from the previous year and this disease could be caused by environmental factors spreading widely in one area to another. Therefore, this study aims to determine the relationship between environmental factors and the DHF in Klaten Regency with a sample of 26 subdistrict. The secondary data were used including population density, rainfall, urban areas, the length of the road network, and the area of forestry/plantation. Data were analyzed by univariate and spatial autocorrelation analysis of Moran Index and LISA using Geoda 1.18. The spatial autocorrelation analysis with Moran Index resulted in a positive spatial relationship between population density, rainfall, proportion of urban areas, road density, and vegetation cover with DHF. Meanwhile, local spatial analysis with LISA resulted in positive and negative spatial relationship and resulted in hotspot areas on environmental factors with the DHF. It can be concluded that intervention on environmental conditions would be necessary as to decrease its negative impacts.
ABSTRAK
Kasus Demam Berdarah Dengue (DBD) di Kabupaten Klaten masih mengalami peningkatan dari tahun sebelumnya dan penyakit ini dapat disebabkan oleh faktor lingkungan yang menyebabkan kasus ini menyebar luas dalam satu wilayah ke wilayah lainnya. Oleh karena itu, penelitian ini bertujuan untuk mengetahui hubungan antara faktor lingkungan dengan kejadian DBD di Kabupaten Klaten dengan sampel sebanyak26 kecamatan. Data yang digunakan berupa data sekunder yaitu kepadatan penduduk, curah hujan, wilayah perkotaan, panjang jaringan jalan, serta luas area perhutanan/perkebunan. Data dianalisis secara univariat dan analisis autokorelasi spasial Indeks Moran dan LISA menggunakan Geoda 1.18. Analisis autokorelasi spasialdengan Indeks Moran menghasilkan hubungan spasial yang positif antara kepadatan penduduk, curah hujan, proporsi daerah perkotaan, panjang jalan serta tutupan vegetasi dengan kejadian DBD. Sementara itu, analisis spasial secara lokal dengan LISA menghasilkan hubungan spasial yang positif dan negatif serta menghasilkan daerah hotspot pada variabel faktor lingkungan dengan kejadian DBD. Hal ini dapat disimpulkan bahwa intervensi pada kondisi lingkungan akan diperlukan untuk mengurangi pengaruh yang negati
Kepedulian Masyarakat terhadap Pengendalian Demam Berdarah Dengue (DBD) Saat Pandemi Covid 19 di Indonesia
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The government, health workers and the public are very focused on controlling Covid 19, this reduces efforts to control DHF so that during the Covid 19 pandemic, dengue cases increase. This study is aimed to know the community awareness of dengue control during the Covid 19 pandemic. A quantitative method with a survey design was used in this study. The sampling technique was accidental sampling with 215 samples throughout Indonesia. Data collection was carried out online using Google Forms from May to June 2021. The results showed that the relationship between gender and all variables of public awareness of DHF control did not have a significant relationship, and the majority of the community were willing to be involved in all efforts to control DHF. There was a significant relationship between education level and willingness to drain clean water reservoirs at home (p value = 0.005) and disease control priority (p value= 0.002). There was a significant relationship between type of work and priority of disease control (p value=0.001). There was a significant relationship between the perception and the willingness to check larvae at home, each showing a significant relationship (p value = 0.015). The awareness of the community for controlling DHF is good.
ABSTRAK
Kasus DBD terus meningkat akibat menurunya upaya pengendalian DBD karena pemerintah, tenaga kesehatan dan masyarakat fokus pda pengendalian Covid 19. Tujuan dari penelitian ini adalah untuk mengetahui kepedulian masyarakat terhadap pengendalian DBD pada saat pandemi Covid 19. Metode penelitian adalah kuantitatif dengan desain survei. Teknik pengambilan sampel dengan accidental sampling dengan 215 sampel di Indonesia. Data diambil secara online menggunakan google form pada bulan Mei sampai Juni 2021. Hasil menunjukkan bahwa hubungan antara jenis kelamin dengan semua variabel kepedulian masyarakat terhadap pengendalian DBD tidak terdapat hubungan yang signifikan (p value ≥ 0,05), dan mayoritas masyarakat bersedia dilibatkan dalam semua upaya pengendalian DBD. Terdapat hubungan yang signifikan antara tingkat pendidikan dengan kesediaan menguras tempat penampungan air bersih di rumah (p value = 0,005) dan dengan prioritas pengendalian penyakit (p value = 0,002). Terdapat hubungan yang signifikan antara jenis pekerjaan dengan prioritas pengendalian penyakit (p value = 0,001). Terdapat hubungan yang signifikan antara persepsi dengan kesediaan memeriksa jentik di rumah masing masing (p value = 0,015). Masyarakat memiliki kepedulian terhadap pengendalian DBD yang baik
Dental Caries and Habit of Eating Sweet Foods, Drinking Sweet Drinks, and Brushing Teeth Correctly in the Community Aged 15-64 Years
No full textBackground: Dental caries is one of the dental and oral health problems that many Indonesian people complain about. Many dental caries are caused by bad habits, including consuming sweet foods and brushing teeth irregularly. The purpose of this analysis is to determine the relationship between the incidence of dental caries with the habit of eating sweet foods and sweet drinks and the habit of brushing teeth in the community aged 15-64 years in Indonesia.
Methods: The research method is a further analysis of the data Riskesdas 2018 with a cross-sectional and non-interventional design. The research sample was all household members in the selected households. The samples analyzed were household members aged 15-64 years. Implementation of data collection wass done through interviews using a questionnaire. Further analysis of this data was carried out using univariate, bivariate and multivariate methods.
Results: The results showed that the respondent's characteristics, that is age, gender, education, and residence had a significant relationship with the incidence of dental caries, with p-value <0.05 (p=0.0001). The habit of eating sweet foods and drinking sweet drinks and brushing teeth correctly had a significant relationship with the incidence of dental caries, with p-value < 0.005 (p= 0.0001). The results of the multivariate test, almost all factors affect the incidence of dental caries, except for the occupational factor with p-value > 0.05 (p=0.260).
Keywords: Dental caries, sweet foods, sweet drinks, brushing teeth
 
Daya Bunuh Anti Nyamuk Bakar Daun Kemangi (Ocimum basilicum) Pada Nyamuk Aedes aegypti (Studi Pengaruh Konsentrasi Terhadap Kematian Nyamuk Tahun 2022)
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Natural insecticides can prevented people from mosquito bites provides the advantage that it is safe for health. Basil leaves (Ocimum basilicum) contain active ingredients of saponins, flavonoids, essential oils, and tannins that are capable to be used as natural insecticides. The aims of the study was to analyze the killing power ofmosquito coils based on basil leaf powder on the Aedes aegypti. The type of research was a pured experiment with posttest only with control group design. The object of the study used Aedes aegypti mosquitoes aged 2-5 days with 25 mosquitoes for each treatment. The treatment group exposed to various concentrations of mosquito coils basil leaf powder 50%, 60%, and 70% with six replications for 20 minute and mosquito mortality will be counted 24 hours after exposured. The quality of the mosquito coil basil leaf powder O. basilicum met the standards of SNI 06-3566-1994. The results of the One Way Anova test indicate that there was at least one concentration of mosquito coil basil leaf powder O. basilicum) which has a higher killing power of Aedes aegypti mosquitoes. The probit test results show that the value of LC50 is 61,763%. Increased concentration needed to get effective killing power.
ABSTRAK
Penggunaan insektisida alami untuk menghindarkan masyarakat dari gigitan nyamuk memberikan keuntungan yaitu aman bagi kesehatan. Serbuk daun kemangi (Ocimum basilicum) memiliki kandungan bahan aktif saponin, flavonoid, minyak atsiri dan tanin yang mampu menjadi insektisida alami. Pemanfaatan serbuk daun kemangi sebagai anti nyamuk bakar aplikatif untuk diterapkan di masyarakat. Penelitian ini bertujuan untuk menganalisis daya bunuh anti nyamuk bakar berbahan serbuk daun kemangi pada nyamuk Aedes aegypti. Desain penelitian adalah posttest only with control group design. Objek penelitian nyamuk Aedes aegypti berusia 2 - 5 hari yang berjumlah 25 tiap perlakuan akan dipaparkan dengan anti nyamuk bakar serbuk daun O. basilicum konsentrasi 50%, 60% dan 70% dengan enam kali replikasi selama 20 menit dan diamati jumlah kematian nyamuk setelah 24 jam. Analisis data menggunakan uji probit dan One Way Anova. Kualitas mutu anti nyamuk bakar serbuk daun O. basilicum memenuhi standar SNI 06-3566-1994. Uji Anova menunjukkan minimal satu pasang konsentrasi anti nyamuk bakar serbuk daun O. basilicum yang mempunyai daya bunuh lebih tinggi. Hasil uji probit menunjukkan nilai LC50 sebesar 61,763%. Peningkatan konsentrasi perlu dilakukan untuk mendapatkan daya bunuh yang efektif
PERSEBARAN DAN POTENSI ETNOFITOMEDIKA KASTURI (Mangifera casturi Kosterm): STUDI KASUS PADA MASYARAKAT SUKU BANJAR DI KABUPATEN INDRAGIRI HILIR, PROVINSI RIAU
Get PDFMangifera casturi Kosterm (Kasturi) memiliki nilai konservasi yang tinggi karena telah dinyatakan sebagai spesies yang punah di alam. Selain nilai konservasi yang tinggi, spesies ini juga merupakan spesies endemik pulau Kalimantan dan identitas flora Provinsi Kalimantan Selatan. Di Provinsi Riau, penyebaran kasturi tidak terlepas dari masuknya masyarakat suku Banjar dari Kalimantan Selatan pada tahun 1860an. Hal ini dibuktikan dengan penyebaran kasturi hanya terdapat di perkampungan masyarakat banjar yang ada di Kabupaten Indragiri Hilir Provinsi Riau. Masyarakat banjar di Kabupaten Indragiri Hilir memanfaatkan kasturi sebagai sumber bahan pangan (buah-buahan) dan buah ini juga dipercaya dapat mengatasi penyakit kembung dan masuk angin. Berdasarkan analisis metabolit sekunder pada aril dan kulit buah Kasturi, senyawa umum yang ada antara lain 5-Hydroxymethylfurfural merupakan senyawa golongan aldehid, Palmitic acid merupakan senyawa golongan asam lemak jenuh dan Ethyl palmitate merupakan senyawa golongan asam lemak