Instituto de Neurociencias de Alicante

RediUMH (Universidad Miguel Hernández)
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    Evidencia sobre el control de la diabetes mediante un estilo de vida saludable promovido por la atención primaria: una revisión sistemática

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    La diabetes mellitus tipo 2 representa uno de los retos de salud pública más significativos a escala global, no solo debido a su alta prevalencia, sino también por las complicaciones que provoca y los elevados gastos de salud. Es una enfermedad crónica que se caracteriza por niveles constantemente altos de glucosa en la sangre, producto de un trastorno en la generación o función de la insulina. De acuerdo con cifras recientes de la Federación Internacional de Diabetes (FID), existen actualmente más de 537 millones de individuos que padecen esta enfermedad, y se estima que seguirá aumentando. En España, la situación es particularmente alarmante, con una prevalencia del 14,8% y un porcentaje considerable de casos sin diagnóstico, lo que eleva la probabilidad de sufrir complicaciones graves como patologías cardiovasculares, nefropatías o amputaciones. Ante esto, adoptar un estilo de vida saludable con dieta, ejercicio y educación en salud es clave para prevenir y controlar la DM2. Sin embargo, el cumplimiento constante de estas prácticas sigue siendo un desafío para muchos pacientes. En este contexto, la atención primaria se destaca como un elemento esencial, dado que es el primer nivel de interacción con el sistema de salud y el lugar ideal para intervenciones de salud, seguimiento y educación. El objetivo de esta revisión sistemática es examinar el efecto de la dieta y el estilo de vida en la regulación de la glucosa en sangre de individuos con Diabetes Mellitus 2, además de evaluar el rol que juega la atención primaria en la promoción de hábitos saludables. Además, se busca identificar obstáculos y factores que afectan el cumplimiento de los pacientes con las recomendaciones médicas y nutricionales, con el objetivo de proponer tácticas efectivas en el contexto comunitario.Type 2 diabetes mellitus represents one of the most significant global public health challenges, not only due to its high prevalence but also because of the complications it causes and the substantial healthcare costs involved. It is a chronic disease characterized by persistently high blood glucose levels resulting from impaired insulin production or function. According to recent data from the International Diabetes Federation (IDF), over 537 million people currently suffer from this condition, and the number is expected to continue rising. In Spain, the situation is particularly concerning, with a prevalence of 14.8% and a significant proportion of undiagnosed cases, increasing the risk of severe complications such as cardiovascular diseases, nephropathies, or amputations. In response, adopting a healthy lifestyle through proper diet, regular physical activity, and health education is essential for the prevention and management of type 2 diabetes. However, maintaining these habits consistently remains a challenge for many patients. In this context, primary care plays a critical role as the first point of contact with the healthcare system and the ideal setting for health interventions, follow-up, and education. The aim of this systematic review is to examine the impact of diet and lifestyle on blood glucose regulation in individuals with type 2 diabetes mellitus, as well as to assess the role of primary care in promoting healthy behaviors. Additionally, it seeks to identify barriers and factors affecting patients' adherence to medical and nutritional recommendations, in order to propose effective strategies within the community setting

    The impact of PM2.5 sources on the single scattering albedo at a rural site in the south-western Mediterranean region

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    In the present work, the contribution of PM2.5 sources to light absorption (σap,520) and scattering (σsp,525), as well as their impact on SSA values, was analysed. For this, measurements of aerosol optical properties and PM2.5 chemical composition were conducted at a rural site in southeastern Spain. The sources that significantly contributed to light extinction were: road traffic (TR), biomass burning (BB), mineral dust (MD), and a secondary aerosol source (SA). BB accounted for nearly 50 % of the absorption coefficient (λ = 520 nm), while the SA source exhibited the largest contribution to the scattering process (~47 % at 525 nm). MD showed the smallest contribution to σap,520 and σsp,525, although its contribution significantly increased during Saharan dust events (SDEs). SSA daily values showed a clear dependence on the contribution of individual sources to PM2.5 concentrations. SSA values (λ = 525 nm) exceeding 0.90 were observed when contributions from secondary aerosols were greater than 50 %, while the SSA decreased with the increase in the contribution from road traffic. The contribution from BB was fairly constant for almost all SSA values, although high SSA values (>0.90) were observed when the contribution from this source was very low. The SSA showed a clear spectral dependence that varied according to the aerosol type. So, for BB aerosols the SSA decreased with wavelength, while for mineral dust the opposite trend was observed

    Emerging narratives in Spanish cinema: Thematic diversification in contemporary (local) production

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    Durante las primeras décadas del presente siglo, el panorama cinematográfico español ha experimentado una profunda transformación estructural, marcada por la descentralización y diversificación de su industria audiovisual. Este proceso ha generado un escenario sin precedentes para la producción de obras con mayor diversidad temática, cultural y de género; reconfigurando tanto la geografía de la industria, como mejorando las condiciones laborales de profesionales y empresas, permitiéndoles desarrollar su actividad en sus lugares de origen sin necesidad de desplazarse a los centros hegemónicos de producción. Este artículo se basa en el análisis de la producción de largometrajes de ficción en España entre los años 2000 y 2023, considerando un corpus de 5246 títulos. Donde se examinan los ritmos de crecimiento, patrones territoriales y los factores explicativos que sustentan esta reconfiguración, prestando especial atención a las comunidades que han experimentado un desarrollo más significativoDuring the first decades of this century, the Spanish film industry has undergone a profound structural transformation driven by the decentralization and diversification of its audiovisual industry. This process has created an unprecedented scenario for the production of works with greater thematic, cultural, and gender diversity, while simultaneously reshaping the geography of the industry and improving working conditions for professionals and companies, enabling them to carry out their activities in their places of origin without the need to relocate to hegemonic production centers. The analysis focuses on the production of fiction feature films in Spain between 2000 and 2023, based on a corpus of 5246 titles. It examines growth trends, territorial patterns, and the explanatory factors underlying this reconfiguration, with particular attention to the regions that have experienced the most significant development

    Decoding Fluorine Peripheral Substitution Impact in Zinc Phthalocyanines for Perovskite Solar Cells

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    We designed six zinc phthalocyanine derivatives (ZnPc-1-ZnPc-6) as molecular semiconductors. By adjusting peripheral substituents with differing electron-donating and -withdrawing properties (-C(CH3)3, -O(CH2)CF3, -CF3), we rationalized solubility, energy levels, and molecular arrangement to influence interfacial charge dynamics and thus device performance. Among the derivatives, ZnPc-2 with three tert-butyl groups and a trifluoroethoxy provides favorable energy level alignment, better thin film coverage, and high conductivity suited to be used as hole-selective materials. When integrated into n-i-p architecture perovskite solar cells, it measures a power conversion efficiency approaches that of Spiro-OMeTAD under our lab conditions. ZnPc-2 showed ambient operational stability, maintaining around 80% of its initial JMPP over 24 h without encapsulation. Our combined theoretical and experimental assessment revealed detailed electro-optical properties to substantiate the influence of molecule design on the device performance. Specifically, three tert-butyl groups with a trifluoroethoxy arm outperform, evidencing molecular design as a strategy to modulate properties

    RTVE Play as a public service audiovisual media platform: a model to rethink

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    La evolución del sector audiovisual tras la popularización del modelo disruptivo de las plataformas ha obligado a los poderes públicos a actualizar sus marcos normativos. En este contexto, los Medios de Servicio Público (PSM) han implantado estrategias corporativas y comerciales para competir con operadores transnacionales, dotados de mayores capacidades económicas y productivas, subordinando en ocasiones su misión de servicio público. En este artículo, estudiamos el caso de la plataforma pública RTVE Play, analizando su grado de cumplimiento de los preceptos de la Ley 13/2022 General de Comunicación Audiovisual, que impone mayores obligaciones a las plataformas, y su grado de transparencia y compromiso, en tanto servicio público, con principios legalmente estipulados como la diversidad lingüística, la protección del menor y la accesibilidadThe evolution of the audiovisual sector following the popularisation of the disruptive platform model has compelled public authorities to update their regulatory frameworks. In this context, Public Service Media (PSM) have implemented corporate and commercial strategies to compete with transnational operators endowed with greater economic and production capacities, at times subordinating their public service remit. In this article, we examine the case of the public platform RTVE Play, analysing the extent to which it complies with the provisions of General Audiovisual Communication Law 13/2022—which imposes greater obligations on platforms—as well as its degree of transparency and, as a public service, its commitment to legally stipulated principles such as linguistic diversity, the protection of minors, and accessibility

    Assessing the social perception of agrivoltaic systems in vineyards. A case study of an integrated trellis-based configuration in South-eastern Spain

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    Sustainable development is a key priority in addressing global challenges such as climate change and land degradation. In South-eastern Spain, the Murcia Region stands out for its agricultural significance and its exceptional potential for solar energy generation, owing to its semi-arid climate and high solar irradiance. However, the rapid deployment of ground-mounted photovoltaic systems has intensified competition for agricultural land, positioning agrivoltaics systems as a promising dual-use solution. This study explores the attitudes of wine tourists towards vertically integrated low-height agrivoltaics systems in vineyards, a sector of major economic and cultural relevance in the region. The methodology consisted of guided visits to pilot low-height vertically integrated agrivoltaics systems installed in vineyard trellises at several wineries, followed by administration of a structured ethically reviewed questionnaire. Statistical analysis reveals a predominantly positive social perception of agrivoltaics systems in vineyards, emphasising support for dual land use and a preference for the low-height system integrated into the trellises, due to its greater harmony with the wine-growing landscape. Differences in perception by gender, educational level and environmental awareness suggests the need for differentiated communication strategies in case actions are taken to further increase the favorable social perception observed. Overall, findings position agrivoltaics as a viable solution for reconciling agricultural and energy production in a context of climate change and resource scarcity

    The economic impact of advertising on Netflix, Prime Video, Disney+ and HBO Max. From SVOD to AVOD

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    Este artículo analiza el impacto económico de la incorporación de publicidad en plataformas de streaming y su relación con la transición desde modelos SVOD hacia esquemas AVOD/HVOD. El objetivo es comparar cómo Netflix, Prime Video, Disney+ y HBO Max reconfiguran su monetización mediante planes con anuncios y qué implicaciones presenta para ingresos, precios y posicionamiento competitivo. A partir de un diseño cualitativo basado en análisis documental y estudio comparado de casos, se triangulan informes corporativos (cartas a accionistas y resultados), documentación sectorial y literatura académica, en el periodo 2022–primer semestre de 2025. Los resultados muestran (i) una convergencia de estrategias hacia planes con anuncios como palanca de crecimiento y segmentación de precios; (ii) un desplazamiento de la competencia desde la mera captación de suscriptores hacia la optimización del ingreso promedio por usuario o ARPU (por sus siglas en inglés) y la diversificación de ingresos; y (iii) una diferenciación estratégica basada en exclusividad de catálogo, bundling, eventos en directo y construcción de marca. Se concluye que el modelo híbrido tiende a consolidarse como estándar emergente, aunque su sostenibilidad a corto y medio plazo depende del equilibrio entre carga publicitaria, tolerancia del usuario y capacidades de segmentación y mediciónThis article examines the economic impact of advertising on streaming platforms and its connection to the shift from SVOD to AVOD/HVOD models. Its aim is to compare how Netflix, Prime Video, Disney+ and HBO Max redesign monetisation through ad-supported tiers and what this implies for revenues, pricing and competitive positioning. Using a qualitative design grounded in documentary analysis and a comparative case-study approach, the study triangulates corporate reports (shareholder letters and earnings releases), industry documentation and peer- reviewed literature for 2022–H1 2025. Findings indicate (i) growing strategic convergence around ad tiers as a lever for growth and price discrimination; (ii) competition shifting from subscriber acquisition alone to ARPU optimisation and revenue diversification; and (iii) differentiation based on exclusive content, bundling, live events and brand building. The article concludes that hybrid models are becoming an industry standard, while medium-term sustainability hinges on balancing ad load, user tolerance and targeting/measurement capabilitie

    Self-learning and the role of the teacher as a motivator in a Medical School in the Dominican Republic

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    Introducción: El análisis crítico y reflexivo, promovido por un docente que motive a los estudiantes que practican el autoaprendizaje, deberá ser asumido como una dinámica constante, que les permita generar conocimiento aplicado. Objetivo: Determinar las intervenciones docentes en el autoaprendizaje y su rol como motivador en una escuela de medicina de la República Dominicana, en el año 2022.Método: Se realizó un estudio prospectivo, de corte transversal, descriptivo, no experimental, utilizando el método inductivo, mediante la aplicación y análisis de una encuesta con 2 preguntas abiertas y 36 cerradas, 1completada mediante un formulario en línea por 109 estudiantes y 21 docentes. Resultados: Se evidenció que el 73.08% de los estudia-dos estuvo totalmente de acuerdo con que el aprendizaje autodirigido y la motivación debe ir de la mano. Por otro lado, el 90.48% de los docentes y el 66.97% (p=0.028) de los estudiantes estuvieron totalmente de acuerdo con que las estrategias que utilice el docente facilitarán que los estudiantes se involucren en los procesos educativos de manera activa, tanto dentro como fuera del entorno áulico. Discusión: El estudiantado participante consideró que la proyección de confianza, empatía y metodologías de enseñanza que utilicen los profesores pueden ayudar grandemente al estudiantado a sentirse motivado y com-prometido en asumir el autoaprendizaje de manera efectiva. De modo que la motivación por parte del docente y la utilización de estrategias que fomenten el autoaprendizaje parecen garantizar el desarrollo holístico del mismo y generará respuestas a las diversas situaciones que se puedan presentar de carácter académico o social. Conclusiones: El docente debe ser un agente generador de cambios, motivando continuamente a sus estudiantes a la búsqueda del conocimiento de manera autónoma y utilizando todas las herramientas innovadoras que garanticen el logro de este objetivo.Introduction: Critical and reflective analysis, promoted by a teacher who motivates students who practice self-learning, should be assumed as a constant dynamic, which allows them to generate applied knowledge .Objective: To determine the teaching interventions in self-learning and its role as a motivator in a medical school in the Dominican Republic, in 2022. Method: A prospective, cross-sectional, descriptive, non-experimental study was carried out, using the inductive method, through the application and analysis of a survey with 2 open questions and 36 closed questions, completed through an online form by 109 students and 21 teachers.Results: It was found that 73.08% of the study participants fully agreed that self-directed learning and motiva-tion must go hand in hand. On the other hand, 90.48% of teachers and 66.97% (p=0.028) of students fully agreed that the strategies used by teachers will facilitate students’ active involvement in educational processes both inside and outside the classroom environment.Discussion: The participating students considered that the projection of confidence, empathy and teaching meth-odologies used by teachers can greatly help students feel motivated and committed to assuming self-learning effectively. Thus, motivation on the part of teachers and the use of strategies that encourage self-learning seem to guarantee the holistic development of the same and will generate responses to the various situations that may arise of an academic or social nature.Conclusions: The teacher must be an agent of change, continually motivating his students to seek knowledge autonomously and using all the innovative tools that guar-antee the achievement of this objective

    Sustainable Development, Environmental Certification and the Financial Performance of the Road Passenger Transportation Sector

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    Within the framework of sustainable development and environmental policy, environmental certification is regarded as a mechanism through which road passenger transport companies (RPTCs) could mitigate their adverse environmental impacts and attain competitive advantages that may enhance their financial performance. The objective of this study is to analyse whether the financial performance of RPTCs improves as a result of the influence that environmental certification exerts on passengers' perceived image, sustainable asset management and employees' environmental behaviour. Using panel data covering the period 2010–2019, a comparative analysis was conducted between certified and non-certified RPTCs, focusing on the routes they operate and their affiliation status. While the effect of certification on sustainable asset management strengthens financial performance, the improvement in passengers' environmental image has only a partial effect. Conversely, the influence of certification on employees' environmental behaviour has been found to exert a negative impact on financial performance

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