Indonesian Journal of Obstetrics and Gynecology (INAJOG)
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Prevalence of Sexual Dysfunction Based on Female Sexual Function Index and Perception of Newly Bride in Jati Village and Its Related Factors
Get PDFObjective: To found prevalence of female sexual dysfunction
based on FSFI and perception of newly bride in Jati Village and its
related factors.
Method: A cross-sectional study was conducted in 33 newlybrides
in Jati Village, East Jakarta, who got married for the first time
within less than 6 months and did not have severe disease. We translated and validated the Female Sexual Function Index (FSFI) and
added items on sexual dysfunction perception. The questionnaires
were self-administered by the respondents.
Results: Almost half (42.4%) of the participants were 26 - 30
years old. The most frequent sexual dysfunction domains were
sexual arousal disorder and sexual pain. Frequency of sexual intercourse was significantly associated with sexual dysfunction based
on FSFI. Marital age and frequency of sexual intercourse were significantly associated with sexual dysfunction based on participants’
perception. Agreement between FSFI score and sexual dysfunction
perception was substantial (Kappa = 0.615, p < 0.001).
Conclusion: The sexual dysfunction prevalence based on FSFI
was 15.2% and based on perception was 12.1%. Participants age and
frequency of sexual intercourse had a significant relationship with
sexual dysfunction. Most of participants who felt that they had
sexual dysfunction did not seek for medical services.
[Indones J Obstet Gynecol 2010; 34-4: 170-4]
Keywords: FSFI, newly bride, prevalence, sexual dysfunctio
Predictive Factors for Pregnancy in IVF: An Analysis of 348 Cycles
Get PDFObjective: To determine predictive factors for pregnancy after
IVF.
Method: The subject of this study were three hundred and forty
eight IVF cycles in 266 couples who underwent controlled ovarian
hyperstimulation in IVF cycles between January 2005 and March
2010. Categorical variables were compared using Chi Square test
and continuous variables were analyzed using Independent t-test, p
< 0.05 was considered statistically significant. Multivariate logistic
regression analysis was done to test correlations between clinical
variables and the occurrence of pregnancy.
Results: The women’s age significantly influenced pregnancy
rate since women under 35 years old has the best chance for pregnancy
(56.4%). Endometrial thickness on the day of hCG administration
also significantly influenced pregnancy in IVF (p < 0.001)
because 64.1% of pregnancy occurred if endometrial thickness ≥
10.95 mm. Serum FSH on 3rd day of period that can predict ovarian
reserve also has significance on pregnancy. On the other hand,
61.5% pregnancy occurred if more than 6 mature oocytes were retrieved
(p < 0.001). Among 92 patients of 348 cycles we found
strong correlation between AMH level with number of mature oocytes
retrieved (p < 0.001; r 0.659). Logistic regression done revealed
the couple with best chance of pregnancy can be described
as follows: women with endometrial thickness ≥ 10.95 mm, number
of mature oocytes > 6 and age under 35 years old.
Conclusion: This study enabled the characterization of many
prognostic factors for pregnancy.
[Indones J Obstet Gynecol 2010; 34-4: 180-4]
Keywords: in vitro fertilization, clinical pregnancy, age, mature
oocytes, endometrial thicknes
A Randomized FiveYear Comparative Study of Two LevonorgestrelReleasing Implant Systems: Norplant® Capsules and Jadena® Rods
Get PDFObjective: To provide a randomized comparison between Jadena®
and Norplant® in terms of efficacy and acceptability among Indonesian
women.
Method: This study was a phase IV, open label, randomized, multicenter
study throughout Indonesia. Subjects were Indonesian adult
women who were randomized to receive Jadena® or Norplant® as
their contraceptive method. The subjects were recruited from 6
large cities in Indonesia, such as Medan, Palembang, Jakarta, Semarang,
Surabaya, and Makassar.
Result: Of 600 subjects, 301 women getting to Jadena® and 299
women to Norplant® were enrolled between August 1998 and
February 1999. The mean age was 29.8 (SD 5.3) years old, ranging
from 18 to 40 years old. We did not find the pregnancy during the
study. Non-pregnancy probability at the end of one year was similar
between Jadena® (0.920 (SD 0.016)) and Norplant® users (0.916
(SD 0.084)). The continuation rates of Jadena® at one and three-year
were 95.3% and 66.8%; whereas, the continuation rates of
Norplant® was 94.3% at year-1 and 70.2% at year-3.
Conclusion: The new two rod levonorgestrel subdermal system
(Jadena®) showed similar efficacy with the old six capsule
levonorgestrel subdermal system (Norplant®) in term of birth
control. Both implant systems also have similar tolerability profile.
Jadena® is easier to insert and remove than Norplant®.
Keywords: birth control, efficacy, implan
Penanganan Adenomiosis dengan Reseksi Laparotomik pada Perempuan Infertil (Pengalaman pada 32 kasus)
Get PDFTujuan: Untuk melihat hasil tatalaksana pengobatan adenomiosis
dengan reseksi.
Rancangan/rumusan data: Kajian retrospektif deskriptif.
Tempat: Klinik Fertilitas dan Menoandropause SamMarie Jakarta.
Bahan dan cara kerja: Dikumpulkan kasus adenomiosis pada perempuan
infertil selama tiga tahun (Januari 1999 sampai Desember
2001) yang diagnosis ditegakkan dengan USG transvaginal. Kasus dilakukan
reseksi secara laparotomi dan dilakukan pemeriksaan Patologi
anatomi sebagai diagnosis pasti adenomiosis uteri. Dan pascareseksi
dinilai perubahan gejala klinis, angka keberhasilan hamil dan laju
kekambuhan.
Hasil: Selama 3 tahun ditangani 1619 kasus infertilitas dan terdapat
66 (4,07%) kasus adenomiosis yang didiagnosis dengan USG trasvaginal.
Sebanyak 32 kasus dilakukan tindakan operasi reseksi dengan hasil
histopatologi menunjukkan 30 (93,75%) kasus adenomiosis dan 2 (6,25%)
kasus mioma uteri. Yang berhasil hamil adalah 3 (9,4%) kasus yaitu dua
kasus melahirkan hidup, satu kasus berakhir dengan abortus 6 minggu.
Dan 25 (78,1%) kasus tidak hamil dan 4 (12,5%) kasus terjadi kekambuhan
penyakit. Hilang gejala tapi tidak hamil 24 (75,35%) kasus.
Kesimpulan: Pengobatan adenomiosis dengan reseksi dapat menyembuhkan
lesi dan dapat terjadi kehamilan. Kekambuhan penyakit dapat terjadi
setelah satu tahun pascareseksi.
[Maj Obstet Ginekol Indones 2008; 32-1: 22-5]
Kata kunci: adenomiosis, reseksi, inferti
Eliminasi Human Papillomavirus (HPV) dan Respons Terapi pada Adenokarsinoma Serviks dan Karsinoma Sel Skuamos Serviks yang mendapat pengobatan Kemoradiasi
Get PDFTujuan: Tujuan penelitian ini adalah untuk mengetahui eliminasi
DNA HPV risiko tinggi pada karsinoma sel skuamous serviks (KSS) dan
adenokarsinoma serviks yang mendapat pengobatan kemoradiasi dan
kaitannya dengan respons pengobatan.
Bahan dan cara kerja: 22 penderita kanker serviks dengan jenis
histopatologi adenokarsinoma dan 26 penderita kanker serviks dengan
jenis histopatoloi KSS yang terdiri dari stadium IB-IIIB (FIGO)
diambil sebagai sampel secara konsekutif dari penderita yang berkunjung
dan dirawat di poliklinik dan ruangan onkologi ginekologi Rumah
Sakit Umum Pusat Nasional Dr. Cipto Mangunkusumo Jakarta
antara Juli 2005 dan Juli 2006. Pemeriksaan DNA HPV risiko tinggi
dengan metode Hybrid Capture 2 (HC2) pada semua sampel tersebut
menunjukkan hasil yang positif. Semua penderita mendapat pengobatan
kemoradiasi. Pascakemoradiasi dilakukan penilaian respons pengobatan
secara klinik dan pemeriksaan HC2 untuk melihat eliminasi
DNA HPV risiko tinggi pada penderita tersebut.
Hasil: Eliminasi DNA HPV risiko tinggi pada kanker serviks jenis
adenokarsinoma lebih kecil dibanding dengan kanker serviks jenis KSS.
Pascapemberian kemoradiasi, pada adenokarsinoma terjadi eliminasi
DNA HPV 59,1% penderita dibanding dengan kelompok KSS di mana
terjadi eliminasi DNA HPV risiko tinggi pada 76,9% penderita. Jenis
Adenokarsinoma juga mempunyai angka persistensi DNA HPV risiko
tinggi yang lebih besar (40,9%) dibanding dengan jenis KSS (23,1%).
Penelitian ini menunjukkan respons pengobatan terhadap kemoradiasi
antara kanker serviks dengan jenis adenokarsinoma dan KSS tidak berbeda
dan hasil analisis menunjukkan bahwa antara respons terapi dan
eliminasi DNA HPV risiko tinggi tidak terdapat hubungan. Pemeriksaan
HC2 pascakemoradiasi masih bisa positif pada tumor dengan respons
komplit.
Kesimpulan: Persistensi DNA HPV risiko tinggi pascakemoradiasi
lebih banyak terjadi pada kanker serviks jenis adenokarsinoma dibanding
dengan jenis KSS. Untuk melihat apakah hal ini berkaitan dengan
terjadinya rekurensi maka diperlukan penelitian dengan waktu pengamatan
yang lebih lama.
[Maj Obstet Ginekol Indones 2008; 32-2: 105-15]
Kata kunci: kanker serviks, HPV, kemoradias
Faktor risiko infeksi saluran kemih pada pertolongan persalinan spontan di RS Moh. Hoesin Palembang
Get PDFTujuan: Menilai pengaruh kateterisasi urin, colok vagina dan keluarnya feses saat mengedan pada pertolongan persalinan spontan terhadap kejadian infeksi saluran kemih.
Tempat: Bagian Kebidanan dan Kandungan Universitas Sriwijaya,
Rumah Sakit Umum Mohammad Hoesin, Palembang - Indonesia.
Bahan dan cara kerja: Penelitian ini merupakan cross sectional
study. 100 orang penderita yang partus spontan diambil secara consecutive sampling. Dilakukan pengisian kuesioner yang memasukkan data mengenai berapa kali kateterisasi dan colok vagina dilakukan, apakah ada kontaminasi feses pada kala II, dan urin diambil menggunakan kateter steril pada mid stream. Urin lalu diperiksa dengan strip nitrit urin.
Hasil: Dari hasil penelitian didapatkan bahwa responden yang positif
infeksi saluran kemih ada 10 responden (10%). Hubungan faktor
risiko dengan infeksi saluran kemih yang meliputi kateterisasi, colok vagina dan kontaminasi feses saat mengedan tidak menunjukkan hasil yang bermakna secara statistik, namun setelah dilakukan uji regresi logistik dan dilakukan penyesuaian didapatkan bahwa colok vagina mempunyai hubungan bermakna dengan infeksi saluran kemih (r 0,544; p 0,019).
Kesimpulan: Angka kejadian infeksi saluran kemih pada persalinan
spontan di rumah sakit Mohammad Hoesin sebesar 10%. Frekuensi
colok vagina memiliki hubungan bermakna dengan kejadian infeksi saluran kemih.
[Maj Obstet Ginekol Indones 2009; 33-1: 14-9]
Kata kunci: infeksi saluran kemih, kateterisasi urin, colok vagin
Distribution of Age, Stage, and Histopathology of Cervical Cancer: A Retrospective Study on Patients at Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia, 2006-2010
Get PDFObjective: To review the distribution of age, stage at presentation, and histology of cervical cancer at Dr. Cipto Mangunkusumo Hospital.
Materials and methods: This cross sectional study involved
2297 subjects with cervical cancer at Dr. Cipto Mangunkusumo Hospital and registered at the Cancer Registration Information System during 5 years period from January 2006 to December 2010. Histotype was confirmed by histopathology examination. The International Federation of Gynecology and Obstetrics (FIGO) classification was used to stage the disease.
Result: The mean age of cervical cancer patients was 51.42 years old (SD 9.694, range 21 - 85). The highest incidence was in 35 - 64 years (87.3%), with the peak incidence in 40 - 59 years (71.3%). There were 0.4 % patients identified at stage IA1, 0.1% at stage IA2, 7.3% at stage IB1, 4.9% at stage IB2, 10.5% at stage IIA,
17.3% at IIB, 1.7% at stage IIIA, 50.2% at stage IIIB, 4.3% at stage IVA, 3.2% at stage IVB. Of the 2297 patients, 70.2% had epidermoid carcinoma, 15.1% had adenocarcinoma, 10.2% had adenosquamous, 0.6% had clear cell, 3.9% had other types.
Conclusion: A large proportion of cervical cancer (76.7%) presented in advanced stage (≥ stage IIB). The highest incidence (57.8%) was in the age range 45 - 59 years. Squamous cell carcinoma is the most frequent histopathology type (70.2%), followed by adenocarcinoma (15.1%) and adenosquamosa (10.2%). A lack of effective
screening programs aimed at detecting and treating precancerous conditions is a key reason for the high incidence of cervical cancer at advanced stage.
[Indones J Obstet Gynecol 2011; 35-1: 21-4]
Keywords: cervical cancer, age, stage, histopatholog
The Role of Dominant Follicular Diameter and LH in Predicting Ovulation in Cycle with Clomiphene Citrate
Get PDFObjective: To improve diagnostic method to predict ovulation in cycle with clomiphene citrate.
Method: This diagnostic research was done in RSUPN Dr. Cipto Mangunkusumo between January 2011 - October 2011 with 31 women who taking CC 50 mg/day and 30 women with normal cycle.
Result: Affecting with ovulation in the two groups, it was found that in groups with CC, the follicle diameter is 24.33 ± 3.87 mm with LH 14.21 ± 7.95 IU/l, meanwhile in normal group, follicular diameter is 17.62 ± 3.45 mm with LH 14.42 ± 5.91 IU/l. Cut-off point for follicular diameter simultaneously with ovulation determined by ROC curve was found in 24.33mm (AUC 0.67, sensitivity 0.64, specificity 0.56), meanwhile the cut-off for LH is 14.40 IU/l
(AUC 0.61, sensitivity 0.57, specificity 0.43).
Conclusion: In group with CC, ovulation occurred in bigger follicular diameter than normal cycle, while LH does not different significantly.
[Indones J Obstet Gynecol 2011; 35-3: 128-9]
Keywords: clomiphene citrate, follicular diameter, luteinizing hormon
Papsmear Examination for Diagnosing PreCancer Lesion in Invisible SquamoColumnar Junction
Get PDFObjective: To know the concealed pre-cancer lesion in women with
invisible squamo-columnar junction (SCJ) by Papsmear examination.
Method: This study was a descriptive cross-sectional design starting
from August 2014 to March 2015 at several Public Health Cares in
Jakarta. A total of 1,682 subjects were screened by Acetoacetate
Visual Inspection (AVI) examination. After the data was collected,
the process was continued by verification, editing, and coding. The
descriptive analysis showed the percentage of SCJ in age distribution,
the percentage of AVI examination based on SCJ, and the percentage
of Papsmear examination in invisible SCJ according to negative
AVI result.
Result: There were 1,484 (88.2%) women with the visible SCJ and
198 (11.8%) women with invisible SCJ. The percentage of invisible
SCJ in the menopausal women group was 122 (61,6%); meanwhile,
in the non-menopausal women group, it was 76 (38.4%). Almost
half of the percentage from visible SCJ was found in menopausal
women group 45.8% (103/225 women). The positive AVI result
was 4 (7.1%) in the menopausal women group and 52 (92.9%) in
non-menopausal women group. The result of Papsmear examination
with invisible SCJ were 197 (100%) normal.
Conclusion: Almost half of visible SCJ was found in menopausal
women group. Most of positive AVI result was found in the nonmenopausal
women group. All women with the invisible SCJ have a
normal Papsmear result.
Keywords: acetoacetate visual inspection, papsmear, pre-cancer lesion,
squamo-columnar junctio
The Characteristics of Preeclampsia with Severe Features
Get PDFObjective: To describe the characteristics of preeclampsia with severe
features and their risk factors.
Method: This study was a retrospective medical record review of
demographic characteristics, obstetric and medical data of preeclampsia
with severe features in Dr. Cipto Mangunkusumo Hospital
from July to December 2014.
Result: There were 1,013 deliveries which 183 patients of them
were diagnosed as preeclampsia with severe features (18.06%). The
study showed 67.76% were 20 - 35 years old, most of them were
multiparity, and 41.53% were preterm labor with 28 - 336 weeks of
gestation then followed by 24.59% were 34 - 366 weeks’ gestation.
Majorities of preeclampsia with severe features patients were without
complication either to the mother or the baby. There were 1 case
of maternal mortality and 15 cases of intra uterine fetal death
(IUFD). There were 73.77% cases delivering by cesarean section.
The complication of the mother in preeclampsia with severe features
was related significantly to the complication in baby, such as
preterm delivery. Besides, women’s age and parity had significant
relationship with baby complication.
Conclusion: There is association of complication in preeclampsia
with severe features women with baby, namely preterm delivery.
Besides, women’s age and parity is related to complication of baby.
Keywords: complication, preeclampsia, risk factor