Indonesian Journal of Obstetrics and Gynecology (INAJOG)
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    Abnormal Trophoblast Invasion: The Culprit of The Major Obstetrics Problems

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    Effectiveness of Participation in Pregnancy Classes to Reduce the Incidence of Obstetric Labor Complications and Cesarean Section

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    Objective : to assess the effectiveness of participation in pregnancy classes to inform such a prenatal program for physicians and midwives, focusing to reduce the incidence of obstetric labor complications and cesarean section. Methods : This study was done using an analytic observational approach, using a cross-sectional study and consecutive sampling. One hundred and ninety-four participants of this study were women aged 20–35 years who gave birth between January and November 2019 in balarejo sub-district, East Java, Indonesia. The subjects were divided into two groups: participation (four times) and non-participation (less than four times) in the pregnancy classes. The analyzed outcomes are labor complications (prolonged labor, postpartum hemorrhage, postpartum fever, premature rupture of membrane), and cesarean section birth.. Results: The results of this study indicate that participants of pregnancy classes have a significantly lower probability of suffering prolonged labor (OR=0.05, 95% CI=0.01-0.23, p<0.05), postpartum hemorrhage (OR=0.20, 95% CI=0.04-0.95, p<0.05), and postpartum fever (OR=0.13, 95% CI=0.16-1.08, p<0.05) compared with non-participants. Also, participating women have a lower chance of undergoing cesarean section (OR=0.08, 95% CI=0.03-0.21, p<0.05). Conclusion : The incidence of obstetric labor complications and cesarean section can be effectively reduced by the participation of pregnant woman class

    Increased Knowledge and Attitudes of Preconception Care using the Dedi Torri Application: Peningkatan Pengetahuan dan Sikap Perawatan Prakonsepsi melalui Aplikasi Dedi Torri

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    Objetive: To determine the increase in knowledge and attitude of preconception care through the application of DeDitorRi.Methods: Uses pre-experiment using a one group pre-test and post-test design.Result: Based on the paired t test in the first health education using the DeDi torRi application to the difference in knowledge obtained with a p value of 0.000 in attitudes with a p value of 0.000. Based on paired t test in the second health education using the DeDitorRi application to the difference of knowledge obtained with a p value of 0.000 and an attitude with a p value of 0.000.Conclusion: Preconception care health education through DeDi torRi (application-based module) and education that is given repeatedly to reproductive age mothers can influence the increase in knowledge and attitude of preconception care.Keywords:  health education applications, preconception care, women of reproductive.     Abstrak Tujuan : Untuk mengetahui peningkatan pengetahuan dan sikap perawatan prakonsepsi melalui aplikasi DeDi torRi. Metode : Pre-eksperimen dengan menggunakan rancangan one group pre-test dan post-test.Hasil: Berdasarkan uji paired t test pada pendidikan kesehatan pertama menggunakan aplikasi DeDi torRi terhadap beda pengetahuan yang didapatkan  dengan p value sebesar 0,000 pada sikap dengan p value 0,000. Berdasarkan uji paired t test pada pendidikan kesehatan kedua menggunakan aplikasi DeDi torRi terhadap beda pengetahuan yang didapatkan  dengan p value sebesar 0,000 dan pada sikap dengan p value 0,000.Kesimpulan: Pendidikan kesehatan menggunakan aplikasi DeDi torRi (aplikasi berbasis modul) efektif dalam meningkatkan pengetahuan dan sikap pada perempuan usia reproduktif terhadap perawatan prakonsepsi. Kata kunci: aplikasi pendidikan kesehatan, perawatan prakonsepsi, perempuan usia reproduktif

    Management of Isolated Tubal Torsion (ALADIN) during Emergency Laparotomy in Infertile Women

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    Introduction: Isolated tubal torsion (ITT) is rare cases with challenging to diagnose. We would like to report ITT and primary infertility patient which came with acute abdominal pain. Case: A 36 yo female came to Koja Hospital with acute abdominal pain without sign of infections. Ultrasound findings show cystic mass on bilateral adnexal sized 76x28x39 mm and 31x51x43 mm with minimal ascites. During laparotomy, proximal right fallopian tube was torsioned four times clockwise. There was hydrosalping founded on contralateral tube, while right and left ovaries and uterus were normal. We performed salpingectomy. Discussion: The clinical presentation of ITT is non-specific and it has become a challenge to physician to develop preoperative diagnosis. The spectrum of imaging findings may be wide range depending on adnexal pathology, degree of severity, and the duration of adnexal torsion. The recommendation of primary approach to tubal torsion is conservative management considering ALADIN (mALignAncy-Death tissue, INfertility). Conclusion: The diagnosis is rarely be made before operation, due to non-specific clinical symptoms and imaging findings. The considerations to perform conservative management are malignancy, death tissue/necrotic, and infertility

    The Efficacy of Chemotherapy in Advanced-Stage Cervical Cancer on Vitamin A Serum: Efektivitas Kemoterapi pada Karsinoma Serviks Stadium Lanjut terhadap Serum Vitamin A

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    Abstract Objective: To determine the efficacy of neoadjuvant chemotherapy on changes of vitamin A serum in advanced cervical carcinoma patient. Method: A randomized clinical trial was performed in the Oncology Gynecology Polyclinic and Ward of Dr. Mohammad Hoesin General Hospital, Palembang from September 2019 to September 2020. There were 30 subjects of advanced cervical carcinoma. Vitamin A levels and tumor volume subjects were assessed before and 1 month after 3 cycles of NAC and analyzed using the Paired T Test and Wilcoxon test. The correlation between vitamin A levels and tumor volume was analyzed by using Spearman's Rho test. Data analysis was using SPSS version 22.0. Results: This study showed statistically not significant increase on vitamin A levels after 3 cycles of NAC chemotherapy (p=0.515). However, there was a significantly decrease in tumor volume after 3 cycles of NAC (p=0.000). In addition, there was a moderate negative correlation between tumor size and vitamin A (r=-0.475; p=0.008). Conclusion: It can be concluded that there was significantly decrease in tumor volume after 3 series NAC chemotherapy and the smaller tumor size, the higher level of vitamin A serum. Keywords: cervical cancer, neoadjuvant chemotherapy, randomized clinical trial, vitamin A,   Abstrak Tujuan: Untuk mengetahui efektivitas kemoterapi neoadjuvan terhadap perubahan kadar serum vitamin A pada karsinoma servik stadium lanjut. Metode: Penelitian uji klinik tanpa pembanding telah dilakukan di Poliklinik dan Bangsal Onkologi Ginekologi RSUP Dr. Muhammad Hoesin Palembang sejak September 2019 hingga September 2020. Didapatkan 30 sampel karsinoma serviks stadium lanjut. Kadar vitamin A dan volume tumor dinilai sebelum dan 1 bulan setelah 3 siklus NAC dan dianalsis menggunakan uji Paired T Test dan Wilcoxon. Korelasi antara Kadar vitamin A dan volume tumor sampel dianalisis menggunakan uji Spearman Rho’s. Analisa data menggunakan SPSS versi 22.0. Hasil : Pada penelitian ini terdapat peningkatan tidak signifikan kadar vitamin A setelah kemoterapi (p = 0,515). Terdapat penurunan secara signifikan volume tumor sebelum dan sesudah kemoterapi NAC 3 seri (p = 0,000).  Selain itu, didapatkan korelasi negatif sedang yang bermakna antara ukuran tumor dan kadar vitamin A ( r = -0,475 ; p = 0,008). Simpulan : Disimpulkan bahwa terdapat penurunan volume tumor setelah kemoterapi NAC 3 series dan semakin kecil ukuran tumor maka semakin tinggi kadar vitamin A dalam serum.  Kata kunci: kanker serviks, kemoterapi neoadjuvan, uji klinik tanpa pembanding, vitamin A

    Nifedipine, Calcium Channel Blocker (Antihypertensive), as a Tocolytic to inhibit Premature Birth in Reducing the Risk of Neonatal Death in Childbirth: Meta-Analysis and Systematic Review of Large Clinical Trial: Nifedipine, Penghambat Kanal Kalsium (Antihipertensi), sebagai Tokolitik dalam Menghambat Kelahiran Prematur dalam Menurunkan Risiko Kematian Neonatus Pada Persalinan: Meta-Analisis dan Telaah Sistematis dari Studi Besar Uji Klinis

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    Objective: To evaluate the role of nifedipine as a tocolytic agent.Methods: Literature searches use medical search engines for example Pubmed, Google Scholar and Medical scientific journals, as like the American kind of Journal that is Learning Obstetrics and also learn about Gynecology. The literature used were published from 1986 to 2020. The main data extraction was in the form of an extended gestation period, divided into 48 hours, 7 days, and 37 weeks with data analysis using the RevMan 5.4 application. Result: Twenty-four clinical trials were analyzed with total amount shown of 2,889 study subjects. The purpose of using kind of nifedipine to be such a tocolytic indicates no significant difference, within 48 hours or (RR 1.06; 95% CI, 0.99 - 1.13; p shown = 0.12), 7 days (RR 1.02; 95% CI, 0.95 - 1.09; p = 0.57), and up to 37 weeks (RR 1.22; 95% then CI, 0.96 - 1.54; p = 0.10) at the time it is compared with the group of control.Conclusion: Administration of nifedipine as a tocolytic did not have a statistically significant difference, both in prolonging pregnancy and side effects for pregnant women and neonates compared to the control group.Keyword: meta-analysis, nifedipine, preterm delivery, prolongation pregnancy, tocolytic.   Abstrak Tujuan: Untuk mengevaluasi peran nifedipin sebagai tokolitik.Metode: Pencarian literatur menggunakan mesin pencari medis seperti Pubmed, Google Scholar dan jurnal ilmiah medis, seperti American Journal of Obstetrics and Gynecology. Literatur yang digunakan dalam rentang tahun 1986 - 2020. Kata kunci adalah ("pregnant woman" OR pregnancy) AND ("preterm birth" OR "preterm labor") AND nifedipine. Ekstraksi data utama berupa perpanjangan masa kehamilan, dibagi menjadi 48 jam, 7 hari, dan 37 minggu dengan analisis data menggunakan aplikasi RevMan 5.4Hasil: Dua puluh empat uji klinis yang dianalisa dengan total 2,889 subjek penelitian. Penggunaan nifedipine sebagai tokolitik menunjukkan tidak ada sesuatu yang berbeda secara signifikan, dalam 48 jam (RR 1.06; 95% then CI, 0.99 - 1.13; p results = 0.12), 7 hari (RR shown 1.02; 95% then CI, 0.95 - 1.09; p = 0.57), dan sampai 37 minggu (RR  1.22;  95%  CI, 0.96 - 1.54; p shown = 0.10) apabila dibandingkan dengan kelompok kontrol. Begitu pun dengan efek samping pada ibu hamil (RR 0.99; 95% CI, 0.74 - 1.31; p = 0.92) dan neonatus (RR 0.93; 95% of CI, 0.83 - 1.04; p shown = 0.21), ditemukan adanya kesamaan yang serupa pada grup atau golongan dalam kendali.Kesimpulan: Pemberian nifedipine sebagai tokolitik tidak memiliki perbedaan yang signifikan secara statistik, baik dalam memperpanjang masa kehamilan maupun efek samping kepada ibu hamil dan neonatus dibandingkan dengan kelompok kontrol.Kata kunci: kelahiran prematur, meta-analysis, nifedipin,  prolongation pregnancy, tokoliti

    Progress of Labor Onset with Combination of Pregnancy Massage and Acupressure: Kemajuan Awal Persalinan dengan Kombinasi Pijat Kehamilan dan Akupresur

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    Abstract Objective: To investigate effectiveness of complementary therapy combination pregnancy massage and acupressure on the onset of labor in primigravida pregnant women. Methods: The population was pregnant women in all regions of Pekalongan Regency at more than 39 weeks' gestation, using random cluster sampling. Data collect use an observation sheet to measure the start time of labor and also check the implementation of massage and acupressure in pregnancy. Treatment was carried out every 2-3 days from 39 weeks of gestation until labor occurs. This study was quantitative quasi-experimental with control group design with a cohort approach. Results:   The results of the bivariate analysis showed that there were significant differences in the onset of childbirth in the intervention group with the control group (p-value; 0.003; CI -8.59 - (- 2.07)). It was concluded that complementary therapy combined therapy of pregnancy massage and acupressure could be used as an alternative therapy to prevent overdue pregnancy Conclusions:   These findings confirm that complementary therapy combination pregnancy massage and acupressure could faster the onset of labor. Keywords: acupressure, complementary therapy, onset  labor, pregnancy massage.   Abstrak Tujuan: Untuk mengetahui efektivitas terapi komplementer kombinasi pijat kehamilan dan akupresur pada permulaan persalinan pada ibu hamil primigravida. Metode: Populasi dalam penelitian ini adalah ibu hamil di seluruh wilayah Kabupaten Pekalongan dengan usia kehamilan lebih dari 39 minggu, dengan menggunakan sampel cluster random. Pengumpulan data menggunakan lembar observasi untuk mengukur waktu mulai persalinan serta memeriksa pelaksanaan pijat dan akupresur pada kehamilan. Pengobatan dilakukan setiap 2-3 hari dari usia kehamilan 39 minggu sampai terjadi persalinan. Penelitian ini merupakan penelitian kuasi eksperimental kuantitatif dengan desain kelompok kontrol dengan pendekatan kohort. Hasil: analisis bivariat menunjukkan terdapat perbedaan yang signifikan timbulnya persalinan pada kelompok intervensi dengan kelompok kontrol (p-value; 0,003; CI -8,59 - (- 2,07)). Disimpulkan bahwa terapi komplementer terapi kombinasi pijat kehamilan dan akupresur dapat digunakan sebagai terapi alternatif untuk mencegah terjadinya kehamilan terlambat. Kesimpulan: Temuan ini mengkonfirmasi bahwa terapi komplementer kombinasi pijat kehamilan dan akupresur dapat mempercepat terjadinya persalinan. Kata kunci: akupresur; awalan persalinan, pijat kehamilan ,terapi komplementer

    Long-term Outcome of Severe Preeclampsia Cases: Cross – Sectional Study: Keluaran Jangka Panjang Kasus Preeklamsia Berat: Studi Potong Lintang

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    Objectives: To investigate the long term outcome of severe preeclampsia mother by clinically and laboratory, and the long  term outcome of the baby that she delivered. Method: This is a cross sectional study was conducted at Obstetrics Outpatient Clinic Dr. Cipto Mangunkusumo General Hospital (Cipto Mangunkusumo NCGH) on January–June 2017, of patients with previous severe preeclampsia that gave birth in Cipto Mangunkusumo NCGHon January 2014 – December 2016, and was descriptively analyze using SPSS Statistics 24. Results: One hundred and twenty seven patients were studied, divided into 3 groups of post – delivery time which were 6 months, 12 months, and 24 months. The 6 months’ group, mean of blood pressure were 147/92 mmHg (SD 38/SD 39), BMI 29 kg/m2 (SD 6), CRP level 16.6 mg/l (0.3 – 42.60) and urine protein dipstick 1 (0 – 3). The 12 months’ group, mean of blood pressure were 112/88 mmHg (SD 12/SD 24), BMI 21s kg/m2 (SD 7), CRP level 12.7 mg/l (3.4 – 15.2) and urine protein dipstick 0 (0 – 3). The 24 months’ group, mean blood pressure 154/95 mmHg (SD 45/SD 62), BMI 28.83 kg/m2, CRP level 14,2 mg/l (SD 8.54) and urine protein dipstick 0 (0 – 3). Meanwhile, the long – term outcome of babies that 68% baby were born with preterm condition and mean birth weight were 1943 grams (SD 1245), the 5th minute Apgar score >7 were 63.78%, and only 44.88% baby had normal growth development. Conclusion: The long – term outcome patients with previous severe preeclampsia are blood pressure, BMI, and CRP level still high, and negative urine protein level until 2 years of post – delivery. The long – term outcome of the babies that delivered were on preterm condition and low birth weight, with less than 50% had normal growth and development. Keywords: c–reactive protein, growth and development, proteinuria, post–delivery, severe preeclampsia.   Abstrak Tujuan: Untuk mengetahui keluaran jangka panjang pada pasien ibu PEB dari sudut klinis dan laboratoris, serta keluaran jangka panjang bayi yang dilahirkan. Metode: Penelitian ini menggunakan desain potong lintang terhadap pasien riwayat PEB yang pernah melahirkan di RSUPN Dr. Cipto Mangunkusumo pada bulan Januari 2014–Desember 2016. Subjek diminta datang ke Poli Obstetri RSUPN Dr. Cipto Mangunkusumo pada Januari–Juni 2017 untuk dilakukan pemeriksaan klinis dan laboratoris (CRP dan protein urin), serta dilakukan analisa deskriptif menggunakan SPSS Statistik 24.   Hasil: Sebanyak 127 pasien yang diteliti terbagi dalam 3 kelompok yaitu pasien riwayat PEB pasca persalinan 6 bulan (kelompok I), 12 bulan (kelompok II), dan 24 bulan (kelompok III). Kelompok I didapatkan rerata tekanan darah (TD) 147/92 mmHg (SD 38/SD 39), IMT 29 kg/m2 (SD 6), kadar CRP 16,6 mg/l (0,3 – 42,60) dan protein urin 1 (0 – 3). Kelompok II didapatkan rerata tekanan darah (TD) 112/88 mmHg (SD 12/SD 24), IMT 21 kg/m2 (SD 7), kadar CRP 12,7 mg/l (3,4 – 15,2) dan protein urin 0 (0 – 3). Kelompok III rerata TD 154/95 mmHg (SD 45/SD 62), IMT 28,83 kg/m2, dengan rerata kadar CRP 14,2 mg/l (SD 8,54) dan protein urin 0 (0 – 3). Sedangkan keluaran jangka panjang bayi yang dilahirkan bahwa 68% lahir dengan kondisi preterm dengan rerata berat lahir 1.943 gram (SD 1.245), nilai Apgar menit ke-5 >7 63,78%, dan hanya 44,88% tumbuh – kembang bayi normal. Kesimpulan: Gambaran keluaran jangka panjang pasien riwayat PEB didapatkan tekanan darah, IMT dan kadar CRP masih tinggi, serta protein urin urin negatif setelah 2 tahun pascapersalinan. Keluaran jangka panjang bayi yang dilahirkan mayoritas kondisi preterm dan berat lahir rendah, dengan kurang dari 50% bayi tumbuh – kembang normal. Kata kunci: c– reactive protein, preeklamsia berat, proteinuria, pascapersalinan, tumbuh kembang bayi

    Germ Patterns and Antibiotic Susceptibility in Pregnancy and Labor with Risk of Infections : Pola Kuman dan Sensitivitas Antibiotik pada Kehamilan dan Persalinan dengan Faktor Risiko Infeksi

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    Objective: To determine the pattern of germs and antibiotic susceptibility tests in pregnant women related to risk factors for infection in preterm PROM cases, the threat of preterm labor, pathological fluor albus, and prolonged labor in Manado city. Method: This study is a cross-sectional descriptive study. A total of 21 samples were obtained, consisting of six preterm PROM cases, five premature contraction cases, five pathological fluor albus cases, and five prolonged labor cases. The study was conducted in Kandou General Hospital and Affiliated Hospitals, Manado. All patients were informed about the study and signed informed consent. Germ pattern and antibiotics susceptibility data were analyzed. Results: Of 21 samples, the detected microorganisms included Staphylococcus aureus (12), Coagulase-negative staphylococcus (2), mixed microorganisms (Staphylococcus aureus + Candida sp, Coagulase-negative staphylococcus + Candida sp), Bacillus sp and Candida sp. The susceptible and safe antibiotics for pregnancy were Ampicillin / Sulbactam and Meropenem. The resistant antibiotics were Ceftriaxone, Tetracycline, and Neomycin. Conclusion: The most common type of bacteria found in pregnant women and women in labor was Staphylococcus aureus. Susceptible and safe antibiotics for pregnancy were Ampicillin / Sulbactam and Meropenem. Keywords: antibiotic sensitivity test, germ pattern, pregnancy and labor infection.   Abstrak Tujuan: Mengetahui pola kuman dan uji sensitivitas antibiotik pada perempuan hamil terkait faktor risiko infeksi pada kasus KPD preterm, ancaman partus prematurus, fluor albus patologis dan partus lama di kota Manado. Metode: Studi ini merupakan studi deskriptif potong lintang. Jumlah sampel yang didapatkan sebesar 21 sampel di mana terbagi pada masing-masing kasus KPD preterm 6 sampel, ancaman partus prematurus 5 sampel, fluor albus patologis 5 sampel dan partus lama 5 sampel. Sampel diambil dari RSUP Prof. Dr. R. D. Kandou Manado dan Rumah Sakit Jejaring di kota Manado yang memenuhi kriteria inklusi dan eksklusi. Semua pasien dijelaskan mengenai prosedur penelitian dan penandatanganan inform consent baru dilakukan pengambilan sampel. Data dianalisis dengan cara deskriptif tentang pola kuman dan uji sensitivitas antibiotik pada kehamilan dan persalinan dengan faktor risiko infeksi. Hasil: Dari 21 sampel, sebaran jenis mikroorganisme diantaranya Staphylococcus areus (12), Staphylococcus non koagulase (2), mikroorganisme campuran (Staphylococcus aureus + Candida sp, Staphylococcus non koagulase + Candida sp), Bacilus sp dan Candida sp. Hasil uji sensitivitas antibiotik yang sensitif dan aman untuk kehamilan di antaranya Ampicillin/Sulbactam dan Meropenem. Hasil uji sensitivitas antibiotik yang resisten adalah Ceftriaxone, Tetracycline dan Neomycin. Kesimpulan: Jenis mikroorganisme paling banyak adalah Staphylococcus aureus. Hasil uji sensitivitas antibiotik yang sensitif dan aman untuk kehamilan di antaranya Ampicillin/Sulbactam dan Meropenem. Kata kunci: infeksi kehamilan dan persalinan, pola kuman, uji Sensitivitas antibioti

    High Random Blood Glucose Level before Surgery as a Risk Factor for Recurrent Event in Epithelial Ovarian Carcinoma : Kadar Gula Darah Sewaktu yang Tinggi sebelum Operasi sebagai Faktor Risiko Kejadian Residif pada Pasien Karsinoma Ovarium Tipe Epitelial

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    Abstract Objective : To investigate the high random blood glucose level as a risk factor for recurrent disease in EOC patient at Kariadi General Hospital. Methods: Sixty six patients diagnosed as EOC in Kariadi General Hospital were divided into 2 groups: 30 patients with recurrent disease and 30 patients without recurrent disease after completing chemotherapy cycles. We analysed correlation between age of diagnosis, tumour mass location, Ca-125 level, histological subtype and random blood glucose level before surgery with recurrent disease. Result: There is no significantly difference in age of diagnosis, tumour mass location and histological subtypes between two groups. However, recurrent EOC patients have higher Ca-125 level significantly than non-recurrent patients (327.8±250.5 vs 183.5±212.1 respectively; p = 0,01). Mean of random blood glucose level of recurrent patients is also higher than non-recurrent patients significantly (150.5 ±79 vs 110.8 ± 31.1 respectively; p = 0.006). Patient with random blood glucose level > 110 mg/dl have 3 times more likely to develop recurrence in EOC patient significantly with 95% CI. Conclusion: The mean of random blood glucose level in recurrent EOC patients is significantly higher than non-recurrent EOC patients. Patient with random blood glucose level > 110 mg/dl have 3 times more likely to develop recurrence in EOC patient. Keyword: epithelial ovarian cancer, random blood glucose level, recurrent.   Abstrak Tujuan: Untuk membuktikan kadar glukosa darah sewaktu yang tinggi sebagai faktor risiko kejadian residif pada pasien karsinoma ovarium epitelial di RSUP dr. Kariadi. Metode: Enam puluh pasien yang telah didiagnosis sebagai karsinoma ovarium epitelial di RSUP dr. Kariadi dibagi menjadi 2 kelompok: 30 pasien pada kelompok residif dan 30 pasien pada kelompok non-residif berdasarkan evaluasi setelah menyelesaikan siklus kemoterapi. Data yang dianalisis meliputi usia saat terdiagnosis, lokasi tumor, kadar Ca-125, subtipe histologi, kadar gula darah sewaktu (GDS) sebelum operasi dan hubungannya dengan kejadian residif. Hasil: Tidak terdapat perbedaan yang bermakna dalam usia saat diagnosis, lokasi tumor dan subtipe histologis diantara kedua kelompok. Namun, kelompok pasien residif memiliki kadar Ca-125 yang lebih tinggi secara bermakna dibandingkan kelompok pasien non-residif (327,8 ± 250,5 vs 183,5 ± 212,1; p = 0,01). Rerata kadar GDS pada kelompok pasien residif juga lebih tinggi secara bermakna daripada kelompok non-residif (150,5 ± 79 vs 110,8 ± 31,1; p = 0,006). Pasien dengan kadar GDS > 110 mg/dl memiliki risiko 3 kali lipat untuk menjadi residif secara bermakna dengan tingkat kepercayaan 95%. Kesimpulan: Rerata kadar GDS pada kelompok pasien residif lebih tinggi secara bermakna dibanding kelompok pasien non-residif. Pasien dengan kadar GDS > 110 mg/dl memiliki risiko 3 kali lipat untuk menjadi residif Kata kunci: kadar gula darah sewaktu, karsinoma ovarium epitelial, residif

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