Journal of Medical Research and Innovation (JMRI)
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Hiccups in the Neuro-Critical Care Unit: A Symptom Less Studied?
Get PDFBackground: Hiccups (also referred to as “hiccoughs”) are usually a transient condition that affects almost everyone in their lifetime. However, persistent and intractable hiccups are the types which are often linked with unfavorable outcomes and can also result in respiratory alkalosis in the intubated patients. There is no accurate estimate of the prevalance of hiccups in the patients admitted in the neuro-ICU.The most commonly witnessed hiccups in the neuro-ICU are intractable and neurogenic in nature. In this communication, we discuss the strategy of respiratory care and pharmacological management of hiccups in an adult male post decompressive craniotomy in view of unilateral basal ganglion bleed. He suffered from persistent hiccups and was managed conservatively with intravenous Metachlorpromide 10 mg on as and when needed (SOS) basis. In conclusion, it seems that persistent and intractable hiccups as a risk factor for ventilator-associated pneumonia in patients who are intubated and mechanically ventilated should be given due attention. We encourage clinical trials in this area of critical care medicine and should also encourage more studies to analyse the effectiveness of non-pharmacological methods
Probiotics for Diarrhea in Children
Get PDFDiarrhea remains the second leading cause of death in children below 5 years of age; in addition it is also the reason for a considerable morbidity in children of all ages throughout the globe. Apart from oral rehydration solution, continued feeding, oral zinc and antibiotics for diarrhea of bacterial etiology, there have been no other proven measures for diarrheal illnesses in children. Probiotics are non-pathogenic live microorganisms. When ingested, probiotics can survive passage through the stomach and small bowel. Probiotics are supposed to have preventive as well as curative effects on several types of diarrhea of different etiologies
End Organ Damage in Hypertensive Geriatric Age Group: A Cross Sectional Study
Get PDFObjective: Hypertension is one of the common risk factors for cardiovascular and cerebrovascular diseases/disorders A developing country like India faces the double burden of communicable and non-communicable diseases; of the which, hypertension is the most important treatable cause of mortality and morbidity with loss of functional capacity and decline in the quality of life. Aim: To study the prevalence of end organ damage in the hypertensive geriatric age group. Method: The present study was a cross sectional study, conducted in 150 elderly patients admitted in MGM Hospital, Navi Mumbai, India with the diagnosis of stage I or II hypertension from 2011 to 2013. Results: Data analysis of the present study showed that 68% of elderly population aged between 60 to 69 years were suffering from hypertension. Compared to males, females had a higher rate of target organ damage. This study found that out of all patients with total end organ damage, 54.6 % had CVS complications, 15.7 % had hypertensive retinopathy, 25.9 % and 18.51 had raised creatinine and proteinuria respectively. 19.4 % had cerebrovascular accident (CVA) complications. Among Cardiovascular related complications Coronary artery disease (CAD) was found in 21 patients, out of them 7 had Congestive cardiac Failure (CCF). Left Ventricular Hypertrophy (LVH) was the most common complication and seen in 38 patients. 13.8 % patients had Regional Wall Motion Abnormality (RWMA) Conclusion: The present study concluded that Isolated Systolic Hypertension (ISH) is the commonest type of hypertension in geriatric age group. This study concluded that the most common risk factors of HTN in the elderly are sedentary life style, dyslipidemia and extra salt intake while the most common end organ damage was observed to be Left Ventricular Hypertrophy followed by renal dysfunction
Retracted Article: Functional Appliances in the Treatment of Class II Malocclusion- A Review
No full textThe article stands retracted due to double submission by the author Dr. Aakash Shah .
It is quite regretful that such authors waste the time and resources of the journal.
View the email sent by Dr. Aakash below.
Functional jaw orthopaedic appliances are a treatment modality for the correction of Class II malocclusions due to mandibular retrusion. A wide range of functional appliances which aim to stimulate mandibular growth by holding the mandible forward is available to correct this type of skeletal and occlusal disharmony. However, the effects of functional appliances are still controversial. Numerous animal experiments and clinical studies have been performed to help ascertain the mechanisms underlying the effects of functional appliances and the optimal timing of treatment. This literature review will be restricted to a discussion of the role of functional appliance therapy in the treatment of class II malocclusions
“Let food be your medicine ….” Inclusion of wheat porridge, a whole grain meal, and legumes lowers postprandial glucose in diabetic patient
Get PDFThe present case report shows the importance of a meal consisting of whole grains and legumes in lowering postprandial glycaemia. A diabetic patient decided to try out diet and lifestyle modification to control the hyperglycemia. He incorporated wheat porridge for his breakfast and dinner along with other food. The postprandial glucose came down to 145 mg/dl after three months. To test the efficacy of wheat porridge in controlling the postprandial glycaemia, the intake of wheat porridge was stopped for 7 days. Then the glucose level increased to 231.4 mg/dl. However, the level came down after restarting the intake of wheat porridge (197.5mg/dl). After adding a small quantity of psyllium husk and black gram (a legume), the postprandial glucose came down to163.5 mg/dl, indicating the protective role in lowering postprandial glycaemia
Microwave-assisted Eco-Friendly Synthesis and Antimicrobial Evaluation of Aryl-Triazole-1,3,4-Thiadiazols
Get PDFDue to the growing awareness about environmental pollution and environmental legislation, recent years have witnessed a phenomenal increase in the application of microwave irradiation (MW) in organic synthesis. Heterocyclic compounds are abundant in nature and are of great significance to life because their structural subunits exist in many natural products such as vitamins, hormones, and antibiotics; hence, they have attracted considerable attention in the design of biologically active molecules and advanced organic chemistry. The application of molecular diversity technique to drug discovery is a multidisciplinary effort in organic synthesis. Medicinal chemistry concerns with the discovery, development, interpretation and the identification of mechanism of action of biologically active compounds at the molecular level. Encouraged by above reports and as part of our research programme for development of eco-friendly synthetic protocol for biologically active compounds as well as in pursuing of our work on new solvent-free cyclisation here we report the synthesis of aryl-triazalo -1, 3, 4-thidiazoles. The one-pot reaction of mercapto-s-triazole with aromatic acid using AlCl3 as a catalyst under microwave irradiation (2-3 min) and in solvent-free condition gave aryl-triazalo -1, 3, 4-thidiazoles with improved yield is described here
Students' Engagement during Collection of Attendance: An Experience of a Pilot Study
Get PDFIn many medical colleges in India, the annual intake for an undergraduate course is 250. Recording attendance of 250 students is a humongous task. It involves an average of 8.93 ± 1.06 minutes, which is approximately 15% of the total time of the one-hour lecture. During this time, students commonly sit idly while waiting for their roll number call. Interestingly, continuous calling of 250 roll numbers at a stretch is an additional voice stress to the teachers. With this background, we designed a program – students’ engagement during collection of attendance (SEdCA). A comprehension test about the lecture topic was conducted in five minutes, and the answer sheets were collected in the next three minutes. These answer sheets were then scanned (i.e., looked at all parts of answer sheets) for roll numbers and were recorded in the register. This method keeps the students engaged in an academic activity during the time of attendance recording. It also helps in reduction of voice stress to the teachers. This method of attendance collection may be adapted by institutions according to available logistics especially when their student’s strength is more than 250
Why should you do Research?
Get PDFToday, the world is facing pandemic outburst of diseases. Many Physicians-Scientist are working really hard to find out the measures which can either prevent or cure these diseases. But, we are still lagging behind in one or the other way. The most important way through which we will be able to curb these diseases is by doing Research. Research is defined as a process of investigation, interpretation and updating of the scientific knowledge. Research is a tool for building knowledge and efficient learning. It is also important for budding and veteran writers, both offline and online. For those looking for a job or a promotion in good hospitals, research is likewise a necessity. It helps in understanding various ongoing health hazards. It is also a way to discard old hypothesis and develop new facts on which the medical world can completely rely on. Research is the need of the day and everyone in medical profession is encouraged to do it including medical students. But their contribution to research is quite less when compared to students of other profession. History says that many inventions were created by medical students. One of the most important research was of insulin discovery and its purification which was made by Dr. Frederick Banting and his second-year medical student assistant Charles Best. Jay Mclean, a medical student from John Hopkins University had discovered Heparin. However, Research should not be made compulsory. Research entails both reading and writing. These two literacy functions help enable computation and comprehension. Without these skills, it is less likely for anyone to appreciate and get involved in research. Reading opens the mind to a vast horizon of knowledge, while writing helps a reader use her/his own perspective and transform this into a more concrete idea that s/he understands. Apart from reading and writing, listening and speaking are also integral in conducting research. Interviews, attending knowledge-generating events, and casual talks with anyone certainly aid in formulating research topics. They can also facilitate the critical thinking process. Listening to experts discuss the merits of their studies helps the listener to analyze a certain issue and write about such analysis. Curiosity may kill not just the cat, but the human as well. Yet, it is the same curiosity that fuels the mind to seek for answers. Indeed, research and doing research encourage people to explore possibilities, to understand existing disorders, and to disclose facts. Without research, healthy life would remain as fantasy. Reading, writing, observing, analyzing, and interacting with others facilitate an inquisitive mind's quest for knowledge and efficient learning. Research serves as an instrument to achieve that healthy world goal
Universal Health Coverage: A burning need for developing countries
Get PDFThe term of universal health coverage (UHC) are getting popularity among the countries who have not yet attained it. Majority of the developing countries are planning to implement the UHC to protect the vulnerable citizen who cannot afford to buy the health services. Poor people living in developing countries, where there is no UHC, are bereft of getting equal health care. They have to bear a significant amount of health cost in buying different services which often causes catastrophic expenditures for an individual and a family. If a country can provide UHC, it will be possible to bring all the citizens under provision of equal and quality care. However, implementation of a UHC is not an easy phenomenon, rather it needs proper design of a good health insurance system by integrating both the public and private health care providers. The influence of good governance and a sustainable health financing system is fundamental to establish UHC in the developing countries
Is Insulin like Growth Factor a new wonder drug?
Get PDFInsulin has been used since a long time to treat Diabetes Mellitus. Little is known about the potential new uses of insulin due to its structural similarities with Insulin Like Growth Factors (IGFs). This brief communication aims to throw light on the potential uses of this hormone and its future prospects