Journal of Medical Research and Innovation (JMRI)
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    Best Paper, Reviewer and Editor Awards - 2017

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    The Journal of Medical Research and Innovation would like to thank each and every one who has helped us in any way possible. We really appreciate it and as a token, we would like to present certificates to the authors of the best paper (based on citations and metrics) of the 2017, reviewer (based on the quality and quantity of reviewing the articles for JMRI) and editor (based on the quantity of work shared with the Editor in Chief).E-Certificates of Appreciation shall be sent through emails to the awardees soon.   Best Paper of 2017 Zaman, S., & Hossain, N. (2017). Universal Health Coverage: A burning need for developing countries. Journal Of Medical Research And Innovation, 1(1), 18-20.   Best Editor of 2017 Dr. Shakti Goel   Best Reviewer(s) of 2017 Dr. Arjun Ballal and Dr. Narayani Srivastava Once again, JMRI would like to congratulate the winners

    Humility: A Key to get Published

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    Humility has been little understood despite being an important part of the scientific writing. Many manuscripts with good data remain unpublished due to their lack of humility leading to repeated rejections. This Editorial aims to highlight the importance of humble writing and how it can be incorporated by authors it in their scientific methodology

    Editors and Reviewers Acknowledgement, 1(3), September-December, 2017

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    The Journal of Medical Research and Innovation would like to thank each and every one who has helped us to review and edit the articles. As a small token of appreciation, we would like to mention the names of all the editors and reviewers in random order here who have edited or reviewed the articles for the September-December, 2017 issue. The list will be updated as when more reviewers review the articles. Editors: Varshil Mehta Shakti Goel Sojib Bin Zaman Reviewers: Varshil Mehta Tushar Kunder Narayani Srivastava Harsha Makwana Charu Dutt Arora Pradeep Jadhav Arjun Ballal Assad Mughal Nasrin Fatah

    Welcome to volume 2 of Journal of Medical Research and Innovation

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    It is my pleasure to introduce the first issue of volume 2 from Journal of Medical Research and Innovation (JMRI). The entire JMRI team is excited to begin our second year journey of publishing good quality-research from across all the medical-related disciplines, all the way from the bench to the bedside. Although we have some quite interesting things planned for 2018, in this Foreword, we will have a look back over some important highlights from volume 1 and some achievements of JMRI from the year 2017

    Atlanto-axial subluxation with cervical myelopathy operated with occipital C2 fusion: A case report

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    Background: Atlantoaxial subluxation with cervical myelopathy is a rare condition that can occur mainly by trauma followed by Rheumatoid arthritis, Grisel syndrome, Down’s syndrome and various other metabolic disorders. It is characterized by excessive movement of atlas (C1) over axis (C2) either by bony or ligamentous abnormality. Due to its laxity the spinal cord may get damaged and cause neurologic symptoms. Reduction and fixation is needed for such instability. Case Report: This 55-year-old gentleman was apparently all right 4 years back when he gradually developed difficulty in walking and imbalance. Bilateral Babinski sign was positive, All deep tendon reflexes were brisk; muscle tone was increased with clasp-knife spasticity present in all four limbs. Ankle and patellar clonus was present bilaterally. His X-ray cervical spine showed C1-C2 subluxation in flexion and extension views. Magnetic resonance imaging (MRI) of Cranio-vertebral junction.  Mild subluxation of atlantoaxial joint (3.1 mm) with posterior displacement of dens causing narrowing of bony cervical spinal canal with reduced distance between posterior aspect of dens of C2 and anterior aspect of posterior arch of C1 vertebrae was noticed. Atlas was also slightly displaced anteriorly in relation to baso-occiput. We managed this patient with occipital cervical fusion after reduction from a posterior approach using screws and rods construct and fusion with bone graft from iliac crest. Post operatively the patient was able to walk without any support and tone of the muscles in lower limb decreased, no tingling or numbness are present, no signs of local infection or inflammation. Conclusion: We suggest to operate atlanto-axial subluxation and cervical myelopathy with occipital C2 fusion

    Dear depression, why do you even exist in the budding medicos?

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    It is a matter of fact that the high demands and pressure of medical school and pre-residency entrance tests pose a tremendous challenge to the personal wellbeing for the physicians in training which leads to high rates of anxiety, burnout, decreased attention, increased incidence of errors, negligence and depression

    Association of Thyroid Stimulating Hormone and Lipid Profile in Pregnancy

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    Introduction: Thyroid hormones have significant functions in embryogenesis and fetal development. Evidence suggests that thyroid stimulating hormone (TSH) may exert extra-thyroidal effects and modify the profile of blood lipids. Aim: To determine the association between maternal blood lipid profile and thyroid stimulating hormone in second and third trimester of pregnancy. Methods & Materials: The present study was carried out at MGM Hospital, Navi Mumbai, India. 200 antenatal cases from October, 2012 to October 2014 were enrolled after taking an informed consent. The blood samples for Thyroid stimulating hormone and lipid profile were taken at 16th and 32nd weeks. Results: The mean TSH level in second trimester was 1.53 mIU/L, with a standard deviation of 1.147 mIU/L. In third trimester, the mean TSH level was increased to 2.60 mIU/L with a standard deviation of 0.836mIU/L. The t-stat value was found to be -10.649 (p < 0.001). In third trimester, TSH was negatively correlated with Cholesterol (r= -0.214, p < 0.01) and VLDL (r= -0.148, p < 0.05). Conclusion: TSH levels rises according to the gestational age, being higher in third trimester as compared to second trimester. There is a significant negative correlation between TSH levels and cholesterol & VLDL in third trimester of the pregnancy. Hence, TSH levels should be looked for, especially in third trimester, in order to keep the thyroid related problems in check

    IGF-1 Therapy in Children with Liver Dysfunction

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    Human growth and development occur as a result of numerous processes which gets initiated under the influence of endocrine hormones. Insulin-like growth factor 1 (IGF-1) plays a most pivotal role in the growth and organ development of a child. IGF-1 is a peptide that belongs to somatomedins group of hormones, also known as somatomedin C. It releases from the liver and other tissues under the influence of growth hormone (GH). The liver is the main protagonist source of IGF-1 hence any disease that can cause liver dysfunction will eventually lead to growth impairment. During the period of growth regulation with GH therapy in liver disease and/or post liver transplantation, the persistent deficiency of IGF-1 proves to be a big challenge to therapy. Growth hormone therapy together with IGF-1 infusion can lead to good results on growth. Therefore, it is important to focus on IGF- level in serum along with Growth hormone while treating a child with poor growth in chronic liver disease and after liver transplantation. The role of IGF-1 therapy should also be considered for better growth and development

    Patient Satisfaction in Chamber Setting in Bangladesh measured by Patient-Doctor Relationship Questionnaire (PDRQ-9 Bangla)

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    Background: Assessment of patient satisfaction is crucial but there is significant lagging in this sector. Patient satisfaction is an important indicator of health care quality as well as a predictor of treatment adherence. The Good patient-doctor relationship is considered as an integral part of the patient satisfaction. In Bangladesh, this domain is yet to be explored in a large scale. Aim: It was aimed to look into the patient satisfaction level in chamber setting in Bangladesh measured using the patient-doctor relationship questionnaire (PDRQ-9 Bangla). Methods: PDRQ-9 is a short yet excellent tool for assessing the patient-doctor relationship. The data collection was done in private chamber setting by the PDRQ-9 and analyzed. Results: Though the result was not completely in line with the existing literature, the PDRQ-9 was found to be a useful and brief measurement tool in the context of the patient-doctor relationship. Conclusion: Large-scale research in this particular aspect of patient satisfaction in future may provide a more succinct resul

    Emergence of New Risk Factors for causing Hypertension

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    The major risk factors which we have been hearing since decades for causing hypertension are high salt diet, obesity, hyperlipidaemia, age, race, consuming tobacco, sedentary lifestyle, stress, drinking too much alcohol etc. However, there are many studies which shows that sugar, fats and low vitamin d levels are equally responsible for causing hypertension. The article will put forward some interesting points to show that sugars, fats and vitamin d levels equally play an important role in causing hypertension

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