South Eastern European Journal of Public Health (SEEJPH - Universität Bielefeld)
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Perspectives of Medical Students on Voluntary Body Donation: A Questionnaire-Based Cross-Sectional Study
Full text linkIntroduction: Voluntary Body Donation (VBD) plays a vital role in medical education and research. However, willingness to donate is influenced by socio-cultural, religious, and educational factors. This study evaluates medical students’ knowledge, attitudes, and willingness toward VBD in India and compares the findings with global trends.Objectives: 1. To assess the knowledge, attitudes, and willingness of medical students toward Voluntary Body Donation (VBD) in the Indian context. 2. To identify factors influencing medical students’ willingness to donate their bodies for medical education and research. 3. To evaluate the role of religious beliefs, cultural influences, and personal ethics in shaping students\u27 perspectives on VBD. 4. To compare the findings with existing global literature on medical students\u27 perspectives on body donation. 5. To explore potential strategies to improve awareness and acceptance of VBD among medical students in India.Methods: A questionnaire-based cross-sectional study was conducted among medical students in Assam, India. Data were collected on demographics, knowledge, attitudes, and willingness to donate. Statistical analysis, including chi-square tests, was performed to assess associations between key variables.Results: A total of 456 medical students participated in the study, providing insights into their knowledge, attitudes, and willingness toward Voluntary Body Donation (VBD). The findings reveal significant associations between willingness to donate and factors such as gender, religious background, and knowledge levels, highlighting key influences on students\u27 perspectives. A significant association was observed (p = 0.0207), with female students showing higher willingness to donate. Religious background had a strong impact (p = 0.00009), with higher opposition among Christians, Buddhists, and Muslims. No significant correlation was found (p = 0.0877), suggesting that cultural and emotional factors outweigh knowledge in decision-making.Conclusion: Knowledge alone is insufficient to drive VBD decisions. Integrating culturally sensitive discussions on ethical and religious aspects of donation in medical curricula is essential. Future research should focus on longitudinal studies to assess evolving attitudes toward VBD among medical students
Topical Gel Containing TNF-α-Activated Mesenchymal Stem Cell Secretome (MSC-CM-T) Increases HMGB1 Expression and Promotes Wound Healing in Full-Thickness Skin Defect Animal Model
Full text linkMesenchymal stem cell conditioned medium or secretome contained several growth factors and cytokines that promote wound healing, thus topical gel containing TNF-α-activated MSC secretome (MSC-CM-T) may be considered as a promising candidate for the treatment of cutaneous wounds. This study aimed to investigate the benefit of MSC-CM-T in promoting wound healing by evaluating changes in wound closure percentage and HMGB1 gene expression. Eighteen Wistar rats were randomly assigned to treatment group receiving 200 µL MSC-CM-T topical gel (9 subjects) and control group receiving 200 µL serum-free DMEM topical gel (9 subjects). A 6 cm incision wounds were made on their backs, and treatment were given twice daily for 6 days. Wound closure were measured using standard calliper, and HMGB1 gene expression were evaluated using quantitative Real-Time PCR. The treatment group showed higher increase of wound closure percentages ( wound closure 46,11±4,41 vs 20.57±6.87 %; p<0.001), HMGB1 expression on day 3 (11.630.28 vs 10.830.31 fc; p<0.001) and day 6 (12.730.29 vs 11.870.31 fc; p<0.001), and HMGB1 expression between day 0–3 (2.650.66 vs 1.810.69 fc; p<0.05) and day 0–6 (3.740.77 vs 2.850.72 fc; p<0.05). This study also found a strong positive correlation between wound closure percentages and HMGB1 expression on both day 3 (r = 0.7231; p<0.001) and day 6 (r = 0.7262; p<0.001). Based on these results, it can be concluded that MSC-CM-T may potentially promote faster wound healing, with HMGB1 as one of the possible factor that mediates this effect
Hydroxyapatite Combined with Graphene Hydrogels for Hemostat Applications: An In Vitro Analysis
Full text linkABSTRACT
Background: Uncontrolled bleeding remains a significant cause of mortality in traumatic injuries and surgical procedures. Hemostatic materials play a crucial role in preventing excessive blood loss and ensuring effective wound healing. Graphene-based hydrogels, particularly when combined with hydroxyapatite (HAP), offer a promising approach for hemostatic applications due to their high porosity, rapid blood absorption, and bioactivity.
Aim: This study aims to fabricate and evaluate HAP-graphene hydrogel membranes as potential hemostatic agents by assessing their clotting efficiency and morphological characteristics.
Materials and Methods: Graphite oxide (GO) was synthesized using the Hummers method. HAP was prepared using calcium carbonate and ammonium hydrogen phosphate under a calcination process. A composite HAP-GO membrane was fabricated by blending HAP and GO in a 1:1 ratio with alginate, followed by cross-linking with calcium chloride. The hydrogels were characterized using Scanning Electron Microscopy (SEM) for surface morphology analysis, and their hemostatic performance was evaluated by measuring clotting time.
Results: SEM analysis revealed a highly porous structure in the HAP-GO hydrogels, facilitating rapid blood absorption and interaction with clotting factors. The clotting time using the HAP-GO hydrogel was significantly reduced to 4 minutes and 10 seconds, compared to the normal clotting time of 5–7 minutes. The improved hemostatic efficiency was attributed to calcium ion release from hydroxyapatite, which accelerates the coagulation process.
Conclusion: The results indicate that HAP-GO hydrogels exhibit enhanced hemostatic properties, making them promising candidates for trauma care and surgical applications. Future research should focus on optimizing mechanical properties and biocompatibility for clinical translation.
Library Services for Users with Disabilities in India: A Bibliometric Analysis.
Full text linkLibrary services for users with disabilities are not just a matter of convenience; they are a fundamental right that ensures equal access to information, education, and knowledge. This literature review sheds light on the significance of accessible libraries, explores the challenges encountered by users with disabilities, and analyzes how libraries can bridge this gap. The 112 articles on this research topic retrieved from Scopus, Google Scholar, ResearchGate, EBSCO, ProQuest and the institutional repositories for the articles in this study. The researcher focused on collecting the literature from 2016 onwards, as the year is very prominent for this study in light of the Rights of Persons with Disabilities Act, 2016 by the Government of India. This study indicates that there is a substantial focus on this subject post 2016 resulting in almost 45% of the total publication in this domain. This study is an key reference for the librarians and policy makers about for establishing the library services to the disabilities in the India context
Applications of Rapid Prototyping in Dentistry
Full text linkRapid prototyping (RP) technology has revolutionized dentistry by integrating computer-aided design and manufacturing (CAD/CAM) to enhance precision, efficiency, and customization in dental applications. RP enables the fabrication of accurate anatomical models, surgical guides, prostheses, and orthodontic devices, reducing manual intervention and improving patient outcomes. The key RP techniques include stereolithography (SLA), selective laser sintering (SLS), inkjet-based 3D printing, and fused deposition modeling (FDM), each offering unique advantages in dental applications. While RP significantly enhances treatment planning, fabrication speed, and accuracy, challenges such as high costs, equipment maintenance, and material limitations remain. The continuous advancements in RP, including AI integration and bioprinting, promise to further transform digital dentistry
Experimental Study On Evaluate The Effectiveness Of Act Out Method On Deficiency Of Outdoor Game Among School Children At Selected Areas Of Visnagar
Full text linkBackground: outdoor play or simply spending time outdoors is beneficial for healthy growth and development among children. .Opportunities for children to engage with outdoor, natural environments may continue to decrease in a constantly evolving socio-environmental world. This prospect became realized with our current experience of the COVID-19 pandemic, where the mass home-confinement directives and restrictions on the use of public outdoor spaces are deterring outdoor play among children. Method: Pre-experimental research design was utilized, Where 60 school children selected through convenient sampling technique. The data collection entailed demographic information and assessment of act out method questionnaire which helps to assess the knowledge regarding outdoor game. Descriptive statistics and inferential statistics were employed for data analysis, where frequency distribution, percentage analysis, mean, standard deviation, and chi-square test of association were applied.Result: The pre-test results indicated that 75% of the participants had Inadequate, 25% moderate adequate, and 0% adequate. The post-test indicated a considerable decrease in score with 8.33% having Inadequate , 13.33% having moderate adequate, and 78.33% have adequate. A statistically significant difference between pre-test and post-test pain scores was noted (p < 0.005), indicating the effectiveness of act out method.Conclusion: The study were need of school children to conduct traning programme regarding outdoor game among school of visnagar. The study reveals that the level of knowledge regarding outdoor game was inadequate among school children. They concluded that need for providing knowledge on outdoor game is an important satatergy utilize school children as effective contribution toward Knowledge
THE MENACE IN BREAST PATHOLOGY
Full text linkDiagnosis by non-operative procedures has of late become the standard of care. This helps the pathologist to make far reaching decisions on small tissue samples. Haematoxylin and eosin (H&E)-stained sections estimation with analytical thinking assisted by the significant use of immunohistochemistry (IHC) and other tests, resume to be the bulwark of histological diagnosis. This review aims to accentuate the hidden difficulty in the interpretation of breast lesions that could diversely guide to under diagnosis, over diagnosis, or incorrect categorization of malignancy, with possible dire after effects to the patients. The review focusses on interpretation of H&E and IHC in breast pathology and aims to complement existing literature on the subject. 1,2,3,4Entities that may result in over diagnosis of malignancy
Union budget – Sustainable development of MSME
Full text linkThis study aims to attempt the role of Micro, Small and Medium Enterprises (MSMEs) in the prospect of the Indian economy. MSMEs play a vital role in the growth of the economy. By 2030, the MSME sector will be anticipated to contribute 40% of the GDP. The union budget related to the MSME sector from 2019-2025 is analysed in the study. The purpose of studying the government’s credit facilities, export-related measures, skill development and infrastructure development by the government of India. The government has increased budget allocation to the Ministry of MSME by over 260% from 2018. 2021-22 budget allocation of 15,700 crores to the MSME sector, which is twice the amount from the 2020-21 budget. India has the highest youth population in the world. Hence, the government taking many measures to improve MSME and generate employment generation. Under Pradhan Mantri Kaushal Vikas Yojana 4.0 launched advanced courses like robotics, AI, etc. in the year 2023-24. The government took action to reduce imports by increasing customs duty, which will boost the market for domestic products and play a vital role in fostering the MSME sector
RETRO-GRADE TRANS PEDAL AND TIBIAL ARTERY ACCESS FOR REVASCULARIZATION OF INFRA-POPLITEAL ARTERIAL OCCLUSIVE DISEASE
Full text linkBackground: Peripheral artery disease (PAD) has reached pan-demic proportions. Percutaneous recanalization of the affected artery is the most important alternative to surgery and appears equivalent to surgery in the management of patients with critical limb ischemia (CLI).Objectives: to evaluate limb salvage after recanalization of lower extremity arteries using retrograde trans-pedal/tibial access using different modalities (US guided, road mapping and cut down) in patients with CLI. Methods: This prospective study included 50 patients of Beni-Suef university hospital with infra-popliteal atherosclerotic occlusive arterial disease. Diagnosis of the underlying arterial ischemia in each patient will be determined from; patient history records and physical exams and using color Doppler ultrasonograpy (US) or CT angiography.Results: 45 patients suffered from Diabetes (90%), 35 patients were cigarettes smokers (70%), 35 patients had dyslipidemia (70%), 30 patients had hypertension (60%), 15 patients suffered from ischemic heart diseases (30%), while 10 patients had renal impairment (20%), 25 patients with failed antegrade (femoral) angioplasty (50%), 15 patients suffered from tissue loss (30%) and 10 patients suffered from rest pain (20%). we used transpedal access in 50 cases, through anterior tibial artery in 30 limbs (60%), and through dorsalis pedis artery in 11 limbs (22%) and posterior tibial artery in 9 limbs (18%) with technical success rate (66%). 2 case developed hematoma (4%) 1 case developed infection (2%) and Perforation in 1 case, there were no major complications. Conclusion: Retrograde pedal/tibial artery access is a promising alternative for patients in whom conventional endovascular techniques failed to achieve recanalization of the tibial vessels