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Neurodiverse Lived Experiences Superimposed on Quality of Life Theories and Models
Get PDFFrom a humanist perspective and using a phenomenological approach, multiple accounts of neurodiversity are juxtaposed with quality of life theories and models. After outlining Aristotle’s Eudaimonia, Amartya Sen’s capability approach, and the Schalock and Verdugo model created in 2002, the validity of each theory or model is tested against the report of a lived experience of neurodiversity. The test used is based on the concept of Gary Albrecht, known as the “Disability Paradox”, an incongruence between the supposed quality of life based on a given theory and the actual reported quality of life of an individual with a disability. If the theory or model outlines a good life as out of reach for a given neurodiverse individual but they report otherwise with substantiated evidence, the theory or model fails the test. Each theory or model is paired with a neurodiverse narrative: Eudaimonia with Count Us In by Mitchell Levitz and Jason Kingsley, the capability approach with The Reason I Jump by Naoki Higashida, and Schalock and Verdugo’s model with Thinking in Pictures by Temple Grandin. Each theory and model pass the disability paradox test with certain critiques, therefore demonstrating that prominent quality of life theories and models suggest that neurodiverse individuals are likely capable of living a good life. </p
Sleep Phenotyping a Subclinical Mouse Model of Alzheimer’s Disease: Response to an Immune Challenge
Get PDFAlzheimer’s disease (AD) is the most common form of dementia, characterized by progressive cognitive decline. The neuropathological hallmarks include Aβ plaques and neurofibrillary tangles. Sleep disturbances are prevalent in AD and emerge early in the disease course, preceding cognitive symptoms. These disruptions include altered circadian rhythms, changes in sleep architecture, and reduced time spent in non-rapid eye movement (NREM) and rapid eye movement (REM) sleep. The goal of this study was to phenotype these sleep disturbances in a preclinical AD model. I utilized APP/tTA mice, an inducible model of AD that allows us to temporally control the expression of amyloid precursor protein (APP) via a tetracycline-off vector system. APP/tTA mice (n=12) were divided into APP-expressing (Dox-off) and control (Dox-on) groups, with APP accumulation induced for three months prior to experimentation. Mice were implanted with EEG headpieces to record sleep-wake states, brain temperature, and movement. Sleep was recorded for 48 hours under baseline conditions, followed by a 6-hour sleep deprivation protocol and subsequent recovery. Mice then received a vehicle saline injection, followed by a lipopolysaccharide (LPS) injection the next day, with sleep monitored for 24 hours post-injection. Sleep phenotyping using ICELUS software focused on total time spent in each sleep stage, sleep-wake transitions, and spectral analysis. I focused on these data in the context of an immune challenge via an injection of LPS. The effects of an LPS injection on sleep architecture in both experimental groups were consistent with that of previous reports. Including an increased amount of time in NREM sleep, decreased time in wakefulness, and a suppression of REM sleep. APP animals experienced alterations in the second 12 hours post-injection demonstrated by a rebound of wakefulness and an undershoot of NREM sleep in the light period that was not seen in control animals. These differences could be attributed to altered homeostatic mechanisms in APP animals. When experimental groups were directly compared, by subtracting saline values from LPS values at the respective timepoints, there were not many differences, demonstrating that both groups followed a similar response to the injection. </p
Justifying Prohibition: U.S. and UN Rhetoric Surrounding Drug Control in Afghanistan, 1993-2001
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After the collapse of the Soviet Union, the U.S. government became less engaged in Afghanistan. However, this paper demonstrates how American policymakers during the 1990s convinced the public and international leaders that heroin and narcotics trafficking continued to be a threat to security and moral values. Historically, American drug policy has been rooted in morality, therefore policymakers built upon this narcophobia to create an “evil” in Afghanistan that the U.S. needed to control and regulate. From this, government agencies pointed to the need to control the supply of heroin in order to mitigate societal issues, such as increasing rates of overdose and increased drug-related crime. With increasing terrorism in the late 1990s from both the Taliban and Al Qaeda, controlling the supply of heroin exported from Afghanistan became even more important since both groups were heavily funded by the opium trade. By using documents released by the U.S. government and UN convention press releases, this paper will explain how the U.S. continued to pursue stricter regulations toward drug control policy and became intertwined with the War on Terror as the Taliban and Al-Qaeda grew more dangerous to American interests. At the same time, evaluating newspaper articles published in the 1990s highlight the rhetoric employed by the government to convince the public that the dangers of the opium trade were especially threatening in Afghanistan. These show an evolution in discourse about drug control policy in Afghanistan and the gradual shift toward punitive measures once the War on Drugs became a step toward simultaneously fighting international terrorism. In combination, these documents illustrate the rhetoric implemented by the U.S. government to justify the continuation of the War on Drugs and its relationship to the War on Terror in later stages. I argue that the rhetoric employed by the American government in the 1990s provides an example of how Washington used drug control policy to pursue goals beneficial to the United States. </p
sPHENIX Electromagnetic Calorimeter Detector Performance During RHIC Run-24
Get PDFsPHENIX is a new experiment at the Relativistic Heavy-Ion Collider (RHIC) that usesits Electromagnetic Calorimeter (EMCal) for measuring energy deposits from a variety ofparticles, including photons from neutral pion (π0) and η meson decays. sPHENIX begantaking data with p+p collisions at √s = 200 GeV in RHIC Run-24. These p+p collisions pro-vide controlled results against which the Quark-Gluon Plasma properties of future Au+Aucollisions will be benchmarked. These p+p collisions also allow for a data-driven calibrationof the EMCal through reconstruction of the π0 or η meson invariant mass, using measuredcluster energies and kinematics. This thesis reviews the π0 and η meson reconstructed massand resolution performance over the course of the run to monitor the effects of accumulatingradiation damage and changing RHIC machine conditions such as the beam crossing angleand beam spot size.</p
New Shades of Blue: Recent Compositional Techniques and Affective Goals in Modern Jazz Fusion
Get PDFThis paper outlines stylistic tendencies of what I call “modern jazz fusion,” (MJF) which fuses rap and hip-hop with precedents from other jazz subgenres. I argue MJF engages with new compositional techniques, facilitating changing aesthetic goals: the single affect composition, and sound complex. Parts I and II define and situate MJF, outlining characteristics and historical precedents (jazz-rock fusion, modal jazz and free jazz) that contribute to the compositional approach. Part III explores the aesthetic goal of sound complex creation based on conversational improvisation. Part IV analyzes the compositions of Kamaal Williams, The Bad Plus, Makaya McCraven, Nubya Garcia and Theo Croker, using analytic frames to explore harmonic loops, rap inspired beats, and ostinati. Finally, part V argues that MJF expands the sonic palette of modern jazz composers and improvisers.</p
NEPC Review: Making the Grade: Accounting for Course Selection in High School Transcripts with Item Response Theory (Annenberg Institute for School Reform at Brown University, December 2024)
Get PDFThe role of test scores in college admissions is widely debated. In their absence, GPA is the primary indicator of readiness, though it depends on course difficulty. An Annenberg Institute report introduces "Transcript Strength," a new measure adjusting GPA based on course rigor. Using Item Response Theory’s partial credit model, it evaluates transcript strength like an educational test. Preliminary findings suggest it offers distinct insights from GPA and SAT scores. While the method is theoretically promising, further research is needed before it can inform policy or admissions decisions.</p
Indian Newspaper Coverage of Climate Change or Global Warming, 2000-2025 - May 2025
No full textThe Media and Climate Change Observatory Data monitors 131 sources (across newspapers, radio and TV) in 59 countries in seven different regions around the world. Data is assembled by accessing archives through the Lexis Nexis, Proquest and Factiva databases via the University of Colorado libraries. More information may be found at: http://mecco.colorado.edu.</p
German Newspaper Coverage of Climate Change or Global Warming, 2004-2025 - April 2025
No full textThe Media and Climate Change Observatory Data monitors 131 sources (across newspapers, radio and TV) in 59 countries in seven different regions around the world. Data is assembled by accessing archives through the Lexis Nexis, Proquest and Factiva databases via the University of Colorado libraries. More information may be found at: http://mecco.colorado.edu.</p
New Zealand Newspaper Coverage of Climate Change or Global Warming, 2000-2025 - April 2025
No full textThe Media and Climate Change Observatory Data monitors 131 sources (across newspapers, radio and TV) in 59 countries in seven different regions around the world. Data is assembled by accessing archives through the Lexis Nexis, Proquest and Factiva databases via the University of Colorado libraries. More information may be found at: http://mecco.colorado.edu.</p
North American Newspaper Coverage of Climate Change or Global Warming, 2000-2025 - April 2025
No full textThe Media and Climate Change Observatory Data monitors 131 sources (across newspapers, radio and TV) in 59 countries in seven different regions around the world. Data is assembled by accessing archives through the Lexis Nexis, Proquest and Factiva databases via the University of Colorado libraries. More information may be found at: http://mecco.colorado.edu.</p
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