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High Abundance of Lachnospiraceae in the Human Gut Microbiome is Related to High Immunoscores in Advanced Colorectal Cancer
Get PDF滋賀医科大学博士（医学）application/pdfThesis or DissertationCancer Immunology, Immunotherapy. 2023 Feb;72(2):315-326.令和4年度thesi
Increased cellular expression of interleukin-6 in patients with ossification of the posterior longitudinal ligament
Get PDF滋賀医科大学博士（医学）application/pdfThesis or DissertationSpine (Phila Pa 1976). 2023 Mar 15;48(6):E78-E86.令和4年度thesi
急性期病院における褥瘡発生の実態解明と関連要因の検討：電子カルテを用いた後ろ向き観察研究
Get PDF滋賀医科大学修士（看護学）application/pdfThesis or Dissertation令和4年度thesi
タショクシュ レンケイ ハイブリッドシミュレーター オ カツヨウシタ シミュレーション エンシュウ ノ ジッシ ト ヒョウカ : ウィズコロナ ジダイ ノ キョウイク ジッセン ニ ムケタ トリクミ
Get PDFCOVID-19の感染拡大により，臨地実習先である附属病院からの受け入れ人数制限の要請があり，2022年度の基礎看護学実習Ⅱは時間を区切って臨地で実習する学生と学内学習をする学生を交互に配置することとなった．臨地での実習時間が限られている状況において，実習目標が達成できるよう本学に今年度から導入された多職種連携ハイブリッドシミュレーターを活用したシミュレーション演習を計画・実施した．本シミュレーション演習に参加することで，学生は呼吸器系疾患患者の観察，フィジカルアセスメントに関する自信を獲得し，高い学習満足度を得ることができたので実践報告する．departmental bulletin pape
Differences in clinical and echocardiographic features and outcomes between atrial functional mitral regurgitation patients with and without posterior mitral leaflet bending.
Get PDFBackground:
Posterior mitral leaflet (PML) bending is a cause of atrial functional mitral regurgitation (AFMR). We aimed to investigate differences in clinical and echocardiographic features and outcomes between AFMR patients with and without PML bending.
Methods:
We retrospectively examined 118 AFMR patients with atrial fibrillation (AF), mild or greater MR without degenerative mitral valve changes, and left ventricular ejection fraction ≥50 %. Patients were classified by the presence of PML bending: PML bending (n=24) and no PML bending (n=94). PML bending was defined as PML-to-anterior mitral leaflet angle ratio ≥3.1 calculated using receiver operating characteristics analysis for eccentric MR jet toward left atrial posterior wall. The study endpoint was a composite of cardiac death, admission for heart failure, and mitral valve surgery.
Results:
Overall, a total of 88 patients (75 %) had mild MR. There were no between-group differences in clinical and echocardiographic characteristics including AF duration and cardiac cavities size except for the length of inward bending of the left ventricular posterobasal wall and the mitral annular area. The 36-month event-free survival for the composite endpoint was significantly lower in the PML bending group (63 % vs. 78 %; Log-rank p=0.047). In multivariate analysis, PML bending was also associated with the composite outcome.
Conclusions:
AFMR patients with PML bending may have worse outcomes than those without PML bending despite similar clinical features.journal articl
RhoA rescues cardiac senescence by regulating Parkinmediated mitophagy
Get PDF滋賀医科大学博士（医学）The Journal of biological chemistry. 2023 Mar;299(3):102993.令和5年度thesi