Journal of Maternal and Child Health (JMCH)
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Is Remakuda Juice Effective to Elevate Haemoglobin Level and Descend Dysmenorrhea in Female Adolescents?
Background: The negative effect of low hemoglobin levels for adolescents can reduce intelligence, learning achievement, mental motor development, inhibition of optimal height growth and reproductive health. Dysmenorrhea is pain or discomfort that occurs in the abdomen during menstruation as a result of prostaglandin secretion which can increase uterine contractions. The purpose of this study was to determine the effect of Remakuda juice on an increase in hemoglobin and a decrease in the intensity of dysmenorrhea in female adolescents.Subjects and Method: An experimental study with no control group was conducted at Junior High School I Tembelang, Jombang, East Java, in September 2021. A total of 60 female adolescents was selected by purposive sampling. The dependent variables were hemoglobin level and dysmenorrhea. The independent variable was Remakuda juice. Dysmenorrhea was measured by the Numeric Rating Scale (NRS) and the Wong Baker Pain Rating Scale. Hemoglobin level was measured by digital haemometer. The data were analyzed using t-test.Results: Hemoglobin levels after intervention (Mean= 2.00; SD= 0.00) were higher than before (Mean= 1.73; SD= 0.45), with p= 0.010. Dysmenorrhea after intervention was lower (Mean= 1.43; SD= 0.59) than before (Mean= 2.70; SD= 0.65), with p<0.001.Canclusion: Remakuda juice can increase hemoglobin levels and reduce dysmenorrhea in female adolescent.Keywords: Remakuda juice, hemoglobin, dysmenorrhea.Correspondence: Zeny Famawati. School of Health Sciences Husada Jombang. Jl. Veteran, Mancar Peterongan, Mancarmalang, Mancar, Jombang 61481, East Java, Indonesia. Email: [email protected]. Mobile: +6282230313559.Journal of Maternal and Child Health (2021), 06(05): 592-599https://doi.org/10.26911/thejmch.2021.06.05.09
The Effect of Recombinant Vascular Endothelial Growth Factor (VEGF)-121 Towards Placenta Growth Factor Serum Levels in Female Mice (Mus Musculus) with Preeclampsia Model
Background: Preeclampsia is a multi systemic disease which recognized by the development of hypertension after 20 weeks of gestation with the presence of proteinuria or any signs indicative of target organ injury. The correct diagnosis and classification of the disease are essential since the therapies are unique in each class. Moreover, the angiogenic factors claims to play a significant role in the endothelial injury which plays as an etiology for preeclampsia. Thus, this study aimed to analyze the differences between angiogenic factors in pregnancy mice with preeclampsia models after administration of VEGF-121.Subjects and Method: Subject of the study were swiss’s strains of pregnancy mice (Mus musculus) which divided into three groups that consist of 10 subject of study in each group. Subjects for this research were recruited between March and May 2015 in Biomedical Laboratory of The Faculty of Veterinary Medicine, Universitas Airlangga as part of a cross sectional study designed for analytical experimental. The angiogenic factor which measured was PIGF serum levels with ELISA method and only group of pregnant mice with preeclampsia model which administred with injection of VEGF-121.Results: This study was conducted of 30 male and 30 female Mus musculus with homogeneous characteristic in terms of age, average body weight and have never been pregnant before. The differences in PIGF serum levels between three observed group are significant (p=0.035).Conclusion: Administration of VEGF-121 increased the PlGF serum levels in pregnant mice with preeclampsia model. Thus, the administration of VEGF-121 improves the condition of endothelial damage in preeclampsia with an increase in PlGF levels.Keywords: angiogenic factors, preeclampsia, placenta growth factor, VEGF-121. Correspondence: Wisnu Prabowo. Department of Obstetrics and Gynecology, Dr. Moewardi Hospital. Kolonel Sutarto 132, Jebres, Surakarta, Central Java, Indonesia. Email: wisnuprabowofetomaternal@gmail.com. Mobile: +6281390015151.Journal of Maternal and Child Health (2021), 06(03): 307-313https://doi.org/10.26911/thejmch.2021.06.03.0
Birth Place Preference and Birth Attendant Selection during Covid-19 Pandemic in Tarakan City, North Kalimantan
Background: Childbirth assistance during the Covid 19 pandemic needs attention to reduce maternal mortality rate and infant mortality rate. This study aimed to analyze the factors influencing the choice of place and birth attendant during the Covid 19 pandemic in Tarakan City.Subjects and Method: This was an observational analytic study with a case control design. The study was carried out in Tarakan, North Kalimantan, Indonesia, in 2020. A sample 100 pregnant women was selected by quota sampling. The dependent variable was the place and birth attendant. The independent variables were place of working, family income, distance to the place of delivery and knowledge. The data were collected by questionnaire using google form. The data were analyzed by a multiple logistic regression.Results: The choice of place of delivery during the COVID-19 pandemic was influenced by place of working (OR= 1.61; 95% CI= 1.49 to 17.02; p= 0.009), family income (OR= 2.57; 95% CI= 3.74 to 45.37; p <0.001), distance travel (OR= 1.53; 95% CI= 0.07 to 0.73; p= 0.014) and knowledge (OR= 1.66; 95% CI= 1.58 to 17.31; p= 0.007). The choice of birth attendant was also influenced by place of working (OR= 1.32; 95% CI= 1.17 to 12.40; p= 0.027), family income (OR= 2.28; 95% CI= 2.94 to 32.23; p <0.001), distance traveled (OR= -1.42; 95% CI= 0.08 to 0.78; p= 0.016) and knowledge (OR= 1.88; 95% CI= 2.05 to 20.85; p= 0.002).Conclusion: The choice of place and birth attendant is influenced by place of working, family income, distance traveled and knowledge.Keywords: place of delivery, birth attendant, pandemic covid 19Correspondence: Ririn Ariyanti. Department of Midwifery, Universitas Borneo Tarakan. Jl. Amal Lama 1 Tarakan, Kalimantan Utara. Email: ririnariyanti.[email protected]. Mobile: +6285345553400.Journal of Maternal and Child Health (2021), 06(01): 122-130https://doi.org/10.26911/thejmch.2021.06.01.1
The Effectiveness of Edutainment toward Pregnancy Care on Knowledge, Attitude, and Action in Pregnant Women
Background: Playing or studying in a pleasant atmosphere is an important factor in education. Through edutainment, pregnant women can facilitate understanding and be able to influence and motivate people's behavior. Learning with the Edutainment method should be able to provide positive benefits to pregnant women so that they can make learning right on target not only cognitive but also affective. Health promotion using a learning method called Edutainment which is expected to provide new solutions in the process of providing education to pregnant women.Subjects and Method: This was an experimental study using pretest and posttest control group design with a randomize controlled trial (RCT). In this design, two groups were randomly selected so that an experimental group was formed with a sample size of 100 pregnant women who were treated with the edutainment method on pregnancy care and a control group with a sample size of 100 pregnant women who were treated with the conventional method. The dependent variable was the knowledge, attitude, and action. The independent variable was Edutainment. Data were collected by questionnaire and analyzed using different test analysis on STATA 13.Results: Knowledge about self-care before pregnant women after receiving edutainment (Mean = 40.54; SD = 2.18) was better than not getting edutainment (Mean= 39.32; SD= 2.26), and the difference was statistically significant (p <0.001). Because there are differences before the intervention (baseline), to determine the effect of edutainment on knowledge, it is necessary to compare the difference in knowledge scores between before and after edutainment in the edutainment group compared with the control group. Attitudes about self-care among pregnant women after receiving edutainment (Mean = 44.15; SD = 1.40) were better than those without edutainment (Mean= 42.28; SD= 2.87), and the difference was statistically significant (p <0.001). Self-care measures for pregnant women after receiving edutainment (Mean= 45.53; SD= 0.74) were better than those without edutainment (Mean= 42.57; SD= 2.58), and the difference was statistically significant (p <0.001).Conclusion: Edutainment is effective to increase the knowledge, attitudes, and practices (behavior, actions) of pregnant women about self-care for pregnancy.Keywords: edutainment, pregnancy care, health educationCorrespondence: Shalsabilla Tiara Firdausia.Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: [email protected]. Mobile: 08222363559.Journal of Maternal and Child Health (2021), 06(01): 56-66https://doi.org/10.26911/thejmch.2021.06.01.06.
Massive Adherent Placenta, Placenta Percreta
Background: Adherent placentas including placenta accreta, increta and percreta are conditions where there is abnormal implantation of all or part of the placenta on the myometrial wall. Massive adherent placenta has high morbidity and mortality rates in both mother and fetus. There is a positive correlation between the incidence of adherent placenta and the increase in cesarean section rates worldwide. Identification of risk factors, antenatal diagnosis, accurate preoperative preparation, multidisciplinary management, and appropriate counseling are the main management of adherent placenta to reduce maternal morbidity.Case Presentation: A woman, G5P3A1, age 36 years pregnant 37 weeks, complained loudly regularly since 6 hours before admission to hospital. There is a history of CS as much as 3x with indications of 2x Premature rupture of the membranes and uterine rupture, as well as a history of curettage (1x). Physical examination showed that the general condition was good, and composting, vital signs were within normal limits. Abdomen palpable single fetus, intrauterine, elongated, head presentation, left back, moderate his (+), FHR 150 x/minute. The results of prenatal sonography examination showed that neither placenta previa nor massive adherent placenta was found. The preoperative diagnosis was inparticular stage I latent phase with a history of SC 3 times.Results: An emergency Caesarean section was performed. Durante surgery showed severe adhesions of the placenta, uterine wall and bladder. The diagnosis of placenta percreta was confirmed, uterine resection was performed on the perreta section, hysterography as well as adhesiolysis and MOW sterilization. The results of the PA examination support the diagnosis of placenta percreta.Conclusion: Massive adherent placenta, placenta percreta was not diagnosed in this case because there were no clinical features or prenatal sonography that supported the diagnosis of placenta percreta. A history of trauma to the uterus due to uterine rupture, history of CS and curettage were risk factors for placenta percreta in this case. The incidence rate of placenta percreta with a history of SC 3 times without placenta previa on the previous sonographic examination was 0.1%. Operative management to manage bleeding and post operative care have been carried out according to the procedure so as to avoid mortality.Keywords: massive adherent placenta, placenta percreta, case reportCorrespondence: Eric Edwin Yuliantara. Department Obstetrics and Gynecology, Faculty of Medicine Universitas Sebelas Maret/ dr. Moewardi General Hospital Surakarta. Jl Kolonel Sutarto 132, Surakarta, Central Java. Email: edwinericog@staff.uns.ac.id. Mobile: 08122618769.Journal of Maternal and Child Health (2021), 06(01): 108-121https://doi.org/10.26911/thejmch.2021.06.01.1
Meta-Analysis the Effect of Oral and Injection Contraceptives on Breast Cancer
Background: Oral contraceptives and injections are the main risk factors for breast cancer. The content of the hormones estrogen and progesterone in oral contraceptives and progestin in injection contraceptives can affect uncontrolled growth of breast tissue, leading to breast cancer. This study aims to analyze the magnitude of the effect of oral contraceptives and injection on the incidence of breast cancer by means of a meta-analysis study.Subjects and Method: This was a systematic review and meta-analysis conducted with PRISMA flow diagrams. Search for articles through journal databases includes: PubMed, Science Direct, and Google Scholar by selecting articles published in 2010-2020. The keywords used were "Women Aged 15-80 Years" AND "Contraceptive Pills" OR "Birth control injections" AND "Breast Cancer". The inclusion criteria were full text articles with observational study design, articles in English, and multivariate analysis used with adjusted odds ratios. Articles that meet the requirements are analyzed using the Revman 5.3 application.Results: A meta-analysis of 15 observational studies showed that oral contraceptives had a 1.30 times risk of developing breast cancer compared with women using non-hormonal contraceptives (aOR= 1.30; 95% CI= 1.13 to 1.50; p= 0.0002). A meta-analysis of 6 observational studies showed injectable contraceptives had a 1.37 times risk of developing breast cancer compared to using non-hormonal contraceptives (aOR= 1.37; 95% CI= 1.09 to 1.71; p= 0.006).Conclusion: Oral hormonal contraceptives and injections have a weak effect on the incidence of breast cancer.Keywords: injection contraception, oral contraception, breast cancer, meta-analysisCorrespondence: Dilma’aarij Riski Agustia. Masters Program in Public Health. Universitas Sebelas Maret, Jl.Ir. Sutami 36A, Surakarta 57126, Jawa Tengah, Indonesia. Email: [email protected]. Mobile: 082230100871.Journal of Maternal and Child Health (2021), 06(02): 238-249https://doi.org/10.26911/thejmch.2021.06.02.1
Multilevel Analysis of Dengue Hemorrhagic Fever in Bantul Regency
Background: Dengue Hemorrhagic Fever (DHF) is one of the main vector-borne diseases infecting humans. It remains a major public health problem in tropical and sub-tropical regions around the world. The poor physical and social environment are the leading cause of the increasing incidence of DHF. This study aimed to determine the effect of the physical and social environment on dengue incidence using multilevel analysis.Subjects and Method: This was an analytic a case-control study conducted in Bantul, Yogyakarta, Indonesia, from November to December 2018. A total of 250 study subjects were selected using the fix disease sampling method. The dependent variable was the incidence of DHF. The independent variables were Maya Index (MI), Density Figure (DF), household crowding, knowledge, mosquito nests eradication, and use of mosquito repellent. The data were collected using a questionnaire. The data were analyzed by using multilevel multiple logistic regression with Stata 13.Results: The incidence of dengue fever was increased with high Maya index (OR= 5.04; 95% CI= 2.38 to 10.67; p <0.001), high density figure (OR= 4.01; 95% CI= 1.90 to 8.44; p <0.001), high household crowding (OR= 1.90; 95% CI= 0.91 to 3.95; p= 0.870), low knowledge (OR= 2.94; 95% CI= 1.41 to 6.12; p= 0.004), poor mosquito nests eradication behavior (OR= 3.09; 95% CI= 1.47 to 6.49; p= 0.003), did not use insect repellent (OR= 3.06; 95% CI= 0.01 to 0.10; p <0.001). Village strata had contextual effect toward the incidence of DHF with Intra-Class Correlation (ICC) by 17.34%.Conclusion: Maya Index, density figure, household crowding, knowledge, mosquito nests eradication behavior, and the use of mosquito repellents affect the incidence of DHF. Village strata have a contextual effect on DHF incidence.Keywords: DHF, Maya Index, density figure, occupancy density, knowledge, mosquito nests eradication Correspondence: Nurkhairani. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36 A, Surakarta, Indonesia. Email: ana[email protected]. Mobile: +6285229185896.Journal of Maternal and Child Health (2021), 06(02): 197-205https://doi.org/10.26911/thejmch.2021.06.02.0
Meta-Analysis the Effect of Intrauterine Device Uptake on the Risk of Ectopic Pregnancy in Women of Reproductive Age
Background: Indonesia has a high Maternal Mortality Rate (MMR) and has not met the Millennium Development Goals (MDGs) target. Maternal mortality in Indonesia is caused by bleeding, hypertension, infection with abortion, and prolonged labor. One of the causes of bleeding in the first trimester is ectopic pregnancy. Several studies have shown an increased risk of ectopic pregnancy in women using intrauterine contraceptives.Subjects and Method: A literature review was carried out in this study with a case control study design. The exposure was intrauterine contraception, and the outcome of the study was an ectopic pregnancy. The initial screening limits studies by time, language and appropriate themes. Furthermore, the selection of research articles was carried out based on the content according to the topic, namely ectopic pregnancy and intrauterine contraceptives, the literature obtained was not duplicated, and each literature was reviewed. Statistical analysis was performed using Rev.Man 5.3 software with a random effects model. Value: the I² statistic was used to calculate heterogeneity.Results: Pooled OR estimates from all studies are (RR= 1.53; 95% CI= 0.48 to 4.80; p= 0.47) with a heterogeneity of 85%.Conclusion: Based on a review of the literature, it can be concluded that intrauterine contraceptives can cause ectopic pregnancy, but the results of the study still show quite varied OR.Keywords: intrauterine contraceptives, ectopic pregnancy, meta analysisCorrespondence: Yulita Endah Mayaningrum. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36 A, 57126, Surakarta, Central Java 57126. Email: [email protected]. Mobile: +6285817887585.Journal of Maternal and Child Health (2021), 06(02): 165-175https://doi.org/10.26911/thejmch.2021.06.02.0
Multilevel Analysis on the Contextual Effect of Village and Sociodemographic Factors on Neonatal Death in Karanganyar, Central Java
Background: Globally, the number of neonatal death in 2018 was 7,000 cases per day. Three-quarters of deaths occurred in the first week of life and 40% of them died in the first 24 hours after birth. Neonatal death is affected by various factors such as direct factors from the baby and indirect factors from the mother. It is also affected by external factors such as socioeconomic conditions. This study aimed to examine the biological and socio-demographic factors affecting neonatal death in Karanganyar Regency, Central Java.Subjects and Method: This was a case control study conducted in Karanganyar, Central Java. The population was all infants at neonatal age in Karanganyar Regency. The sample was 200 respondents with 50 cases of neonatal death and 150 infants who were alive during the neonatal period. This study used fixed disease sampling. The dependent variable was neonatal death. The independent variables were Mid-Upper Arm Circumference (MUAC) of the mother, maternal age, maternal education, maternal occupation, total family income, number of maternal deliveries, and the Alert Village level. The data were analyzed using logistic regression analysis with STATA 14.Results: The risk of neonatal death decreased with maternal MUAC ≥ 23.5 cm (b=-1.19; 95% CI=-2.02 to -0.36; p=0.005); maternal age between 20–35 years (b=-0.98; 95%CI=-1.76 to -0.20; p=0.014); maternal education ≥Senior High School (b=-0.67; 95%CI=-1.46 to 0.12; p= 0.097); unemployed mothers (b= -1.07; 95% CI= -1.95 to -0.19; p= 0.017); total family income ≥Rp 1,833,000 (b= -1.17; 95%CI=-2.04 to -0.30; p=0.008); and the number of birth deliveries of 2-4 (b=-0.79; 95%CI=-1.53 to -0.05; p= 0.036). The level of Alert Village had a very low effect on the risk of neonatal death (ICC was <0.01%).Conclusion: Neonatal mortality is affected by maternal MUAC, maternal age, maternal education, maternal occupation, total family income, and number of maternal deliveries. The level of Alert Village has a very low effect on neonatal death.Keywords: Neonatal death, sociodemographic, motherCorrespondence: Amin Sukoco. Masters Program in Public Health, Universitas Sebelas Maret, Jl. Ir. Sutami 36A, Surakarta 57126, Indonesia. Email: [email protected]. Mobile: +6281329387610.Journal of Maternal and Child Health (2021), 06(02): 207-219https://doi.org/10.26911/thejmch.2021.06.02.0
Lipid Profile (Total Cholesterol, LDL, HDL, Triglyceride) of Injection Contraceptive Acceptors in Semarang
Background: Hormonal injectable contraceptives are the most common choice taken by women. The 3-month injection of contraception is DMPA, one of the most effective contraceptive methods currently used. Using injectable contraceptives, especially DMPA, influences fat metabolism, especially lipoproteins. Changes in fat metabolism cause disturbances in the balance of blood fat fractions (fluctuation of HDL, LDL and total cholesterol levels) due to hormonal influences. Subjects and Method: Descriptive with an observational design study. Seventy-three women accepted injection contraceptive three months with a usage period of more than three years recorded in the Tlogosari Kulon Community Health Center. They were selected based on sample criteria, including inclusion criteria and exclusion criteria, where these criteria determine whether or not the sample can be used. The dependent was lipid profile (cholesterol, trigliceryd, LDL, HDL). The independent variables was contraceptive injections three months. There are seventy-three respondents.Results: The respondents in this study had 3-month injection contraceptive use of were less than the same as six years of use, namely 41 people, while for use more than the same as seven years there were 32 people and show that most of the research respondents had a lipid profile that was still within normal limits. For the cholesterol levels, 23% is normal, and 76% is abnormal, Trigliceryd level 66% is normal, and 34 % is abnormal. LDL levels 100% is normal, and for the HDL levels, 63% is normal, and 37% is abnormal.Conclusion: Most of the lipid profiles of respondents were normal. However, on cholesterol levels, respondents had more abnormal levels than normal, but for other lipid profiles (Trigliceryd, LDL, HDL), most respondents had normal levels.Keywords: lipid profile, injection contraception, DMPA. Correspondence: Surati. Department of Health Analyst, Health Polytechnics, Ministry of Health Semarang. Jl. Wolter Monginsidi, Semarang 50192, Central Java. Email: [email protected]. Mobile: +6285226825024.Journal of Maternal and Child Health (2021), 06(05): 626-631https://doi.org/10.26911/thejmch.2021.06.05.12