Pertanika Journal of Scholarly Research Reviews (PJSRR - Universiti Putra Malaysia, UPM)
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    65 research outputs found

    Ki-67 Protein as a Prognostic Indicator in Ovarian Carcinoma

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    Ki-67 expression is strongly correlated with tumour cell proliferation and growth. It is widely used as a proliferation marker in the routine pathological investigation. The nuclear protein Ki-67 (pKi67) is recognised prognostic and predictive indicator for the biopsies assessment for cancer patients. Clinically, pKi67 has been revealed to associate with metastasis and the clinical stage of tumours. Furthermore, it has been presented that the expression of Ki-67 is significantly higher in malignant tissues with poorly differentiated tumour cells, as compared with normal tissue. The Ki-67 labelling index plays a vital role as an independent prognostic factor for survival rate, which includes all stages and grade categories. There is an association between the ratios of Ki-67 positive malignant cells and patient survival. This review provides an overview of recent advances in detecting Ki-67 in ovarian carcinoma

    Consumer’s Perception on the Quality of Controversial Contents in Edible Bird’s Nest Products

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    Edible bird’s nest (EBN) originates from South East Asia and has become the most popular food delicacy among Chinese people. The price for raw and clean EBN are around RM 4,000 and RM 8,000 per kg, respectively. Due to the high market value of EBN and low maintenance cost, people ventures and invest in bird’s nest industry. The nesting house resembles the cave is built to attract swiftlets to roost and nest in it in order to meet the world’s growing demand. Out of the blue, in 2011, the EBN’s price falls half from its original price from RM 4,000 to RM 2,000. Nitrate found in raw or unclean EBN is one of the reason price plunges and the public also worried about counterfeit EBN that made from unclear substances. Thus, this review paper aims to highlight the nutritional properties in EBN that give medicinal benefits to consumers and the adulterant in EBN to increase the property contents with the dangerous mechanism by some irresponsible producers to obtain better profit which can threatening public’s health. In relation, these matters may influence consumer’s perception on EBN contents that could harm this industry. For that reason, scientific studies determined ways of handling EBN from scratch and distinguished the adulterant in EBN to reduce consumer anxiety was also discussed. Strict standard operation procedure enforces by the Malaysian Ministry of Health to farmers and producers are required, so that Malaysia EBN would appeal to the China market. Latter it can yield a good result and the price of EBN will slowly increase

    An Analysis of Artists’ Practice in Hybrid Art and the Challenges Toward Malaysian Art Scene

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    Living in today's era, artists’ practice in creating artwork is different from those practiced 20 years ago.  With the existence of digital art followed by electronic art in the local art scene, the presentation, style and approach have evolved. Back in 2005 and 2007, some exhibitions brought hybrid art concept into an art exhibition. One of the shows was ‘Hybrid+ism’ which highlighted in various disciplines, media, applying unlimited processes and medium. The purpose of this paper is to study the artists’ practice in the hybrid art based on selected artworks. The artworks are selected based on some criteria ranging from experimental, mixed media, multi-disciplines, integration and technology as well as culture aspects. This paper is discussing the hybrid art practice among artists in the Malaysian art scene and the challenges to creating awareness on hybrid practice among audiences

    A Case Study on Culture-Oriented Design Preferences

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    It is hard to identify the local Malay identity in a design context compared to other cultural oriented design in several countries. This paper tries to uncover how designers interpret local identity embodied agent based on local items influences and understood and the influence of incremental, radical design that changes respective to preceding designs. A descriptive study through the literature reviews focusses on a type of artefact initiated through cultural-oriented design. Based on the preliminary study, a sampling taken from the Chinese, Indian, Japanese or European consistently apply the same fundamental understanding in regards to the culture-oriented design. From the same point of view, teapot seems to be used as one of the dominant artefact indicating the design preferences. This research will benefit both the academia and the industry and identify significant identity based on the local context and become an embodied agent to give impact in establishing  the state-of-the-art of brand, the identity of local design, establish new trademark towards generating domestic, international economy and promote the nation worldwide throughout design platform

    Waterbirds: An Important Bio-Indicator of Ecosystem

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    Waterbirds serve as an important bio-indicator of ecosystem changes and have been used widely throughout the world. This is because they exhibit conspicuous and meaningful responses to the changes of the environment around them. Other qualities that make them a good bio-indicator are also highlighted. Thus, important information on their biology and ecology are essential to make informed decisions. This is crucial in order to better conserve them and their habitats. Currently they are facing new challenges that arise from continuous development throughout the world. In addition, many endangered species continue to declines and could be extinct if they are not protected and conserved. The development of artificial habitat such as wetlands to compensate natural habitat loss could be an alternative.  However, detailed information on the waterbirds and their interactions with the new environment are needed in order to do so. It is further highlighted that few researches have been conducted and focused on the waterbirds particularly in Malaysia. Thus, we encourage more local young scientists to take up this challenge and equip themselves with the right knowledge and necessary skills as well as to remain relevant with the international research standards. Proper planning, funding and focus should also be considered by the government and local authorities to maximize the impact of the country’s conservation effort

    Solid Waste Minimization in Malaysia

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    Malaysia has taken initiative in enforcing the Solid Waste Management and Public Cleansing Act 2007 (Act 672) since 2011 to ensure the uniformity of law relating to the solid waste management and public cleansing. Despite the alarming issues on the increasing of solid waste generation, Malaysian government has made solid waste separation at source as mandatory starting 1st September 2015 at eight states. Solid waste separation at source has been seen as the best practice of solid waste minimization where it eliminates and reduces the amount of solid waste produced by the society. The government has taken seriously in solid waste separation at source as the lifespan of disposal site has been decreased and limited space for the new disposal site due to the increasing cost of solid waste management. Hence, to overcome the increasing of solid waste generation, an integrated solid waste minimization through recycling should be implemented as it is involved in minimizing resource and offers the best outcome for the environment. Thus, this paper discussed the overview of solid waste minimization in Malaysia and the stakeholder’s role and their obstacles in solid waste minimization to attract the public participate in reducing the solid waste generation as an efficient solid waste management. A proper solid waste management ensures a sustainable development of Malaysia in terms of health, socio-economy and environment respectively towards Malaysian Vision of 2020

    Deficient Reinforced Concrete Beam-Column Joint Strengthening

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    Structural buildings in seismic prone area, the required energy dissipation of strong column-weak beam especially for reinforced concrete frame structures is achievably through adequate beam-column joint strengthening connection in order to have high seismic performance. Literature investigation shows several approaches and techniques for modelling the weak joint for a typical frame structure. This paper extensively reviews those techniques, methods, concepts and their performance in improving the shear capacity for a deficient reinforced concrete beam-column joints in withstanding seismic loads. The beam-column joints performance responses showed positive. However, the need for an improved connection that will offer high ductility capacity and energy dissipation ability for post-tensioned reinforced concrete beam-column joints with continuing bottom reinforcement is highly feasible with the use of the Direct Displacement Based design philosophy. This will be of great interest for the future development of highly efficient joint system for frame structure capable of resisting significant seismic load

    Plant Disease Control: Understanding the Roles of Toxins and Phytoalexins in Host-Pathogen Interaction

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    Naturally, plant habitats are exposed to several potential effects of biotic and different abiotic environmental challenges. Several types of micro-organisms namely; bacteria, viruses, fungi, nematodes, mites, insects, mammals and other herbivorous animals are found in large amounts in all ecosystems, which lead to considerable reduction in crop productivity. These organisms are agents carrying different diseases that can damage the plants through the secretion of toxic-microbial poisons that can penetrate in the plant tissues. Toxins are injurious substances that act on plant protoplast to influence disease development. In response to the stress effect, plants defend themselves by bearing some substances such as phytoalexins. Production of phytoalexins is one of the complex mechanisms through which plants exhibit disease resistance. Several findings specifically on phytoalexins have widen the understanding in the fields of plant biochemistry and molecular biology. However, this review reports the interaction of toxins and phytoalexins in plant-pathogen cycle, research progress on the association of phytoalexins with plant disease resistance as well as the role of the phytoalexins in plant disease control

    Environmental Fate and Degradation of Glyphosate in Soil

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    oai:ojs1.pjsrr.upm.edu.my:article/124Commercialisation of glyphosate [N-(phosphonomethyl)glycine] in the early 1970s has left a big leap in the agriculture sector. This is due to its effectiveness in controlling a wide range of weeds. Glyphosate translocates well in plants. In addition, with added surfactant in its formulae, it can also be used in wet conditions. Its ability to kill weeds by targeting the 5-enolpyruvyl-shikimate-3-phosphate synthase (EPSPS) makes no competing herbicide analogs in its class. Considering its cost effectiveness, only small amount is needed to cover a large sector in agricultural land. The most important aspect in the success of glyphosate is the introduction of transgenic, glyphosate-resistant crops in 1996. However, glyphosate is not an environmental friendly herbicide. This systematic herbicide has raised environmental concern due to its excessive use in agriculture. Studies have shown traces of glyphosate found in drinking water. Meanwhile, it's rapid binding on soil particles possesses adverse effect to soil organisms. Glyphosate degradation in soil usually carried out by microbial activity. Microbes’ capable utilising glyphosate mainly as phosphate source. However, the activity of C-P lyase in breaking down glyphosate have not clearly understood. This review presents a collective summary on the understanding on how glyphosate works and its environmental fate

    The Potential of Pumpkin (Cucurbita Moschata Duschene) as Commercial Crop in Malaysia

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    Awareness of recommendations for fruit and vegetable consumption has increased substantially over the last 20 years. In addition, fruits and vegetables such as pumpkin are good sources of many important nutrients, including potassium, vitamin C, folate, fiber, and numerous phytochemicals. Malaysia produces pumpkin of its own, with considerably large areas of production comparable to its high global demand. However, in reality, there is a limitation in the commercial production as the local pumpkin is very much dependent on the market demand as the utilization has been limited to the consumption of fresh product. Thus, the objective of the study first initiative to provide the information about the pumpkin and second to investigates the opportunities on commercialized local pumpkin in Malaysia as by products despite various nutritious it is also listed as prophetic foods. The scientific research that covered a broad range of in vitro to in vivo studies on the by-products potentials of these fruits is also discussed in detail. The current review is an update for researchers to have a better understanding of the pumpkin, which simultaneously can provide awareness to enhance their commercial value and promote their utilization as a prophetic food especially to the Muslim consumer

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