Pertanika Journal of Scholarly Research Reviews (PJSRR - Universiti Putra Malaysia, UPM)
Not a member yet
65 research outputs found
Sort by
Prospective Therapeutic Strategies for Cervical Cancer
Full text linkAbstract – Cervical cancer is one of the leading causal cancer-related fatalities in the world. Cervical cancer patients can be treated by conventional treatment such as surgery, radiotherapy, chemotherapy, medications and combination treatments. Currently, more targeted treatments are being developed to cure cervical cancer. The treatments include immunotherapy, virotherapy and gene therapy which will be discussed in this paper. In immunotherapy, the synergy of CTLA-4 suppression and PD-1/PDL-1 immune checkpoint inhibition targeting their corresponding pathways enhanced the human immune system resulting a promising treatment effects. Oncolytic viruses such as Newcastle disease virus selectively infect and kill cancerous cells/tissues without harming normal cells/tissues. This character has made them a potential modality in combating cancer which popularly known as oncolytic virotherapy. Gene therapy delivers modified genetic materials to the target cancer cells via viral and non-viral vectors. It is used to target the abnormal gene, to increase cells’ susceptibility towards drugs or conventional therapy, to induce tumour cells apoptosis, to enhance tumour cell immunogenicity recognition and to inhibit the oncogene expression. The objective of this minireview is to add to the general knowledge on aforementioned therapeutic strategies against cervical cancer
Ficus caricaL
Full text linkFicus carica L. or fig is the oldest fruit tree that being cultivated by man. Grouped under genus Ficus, this species is grown widely in Mediterranean region and now being cultivated in an area with temperate or sub-temperate climate. Fig planting in Malaysia is still new, which was brought as a hobby at first. Fig is a unique fruit tree as some variety can produce fruits without pollination. Contain lots of carbohydrates, essential amino acids, vitamins and minerals such potassium, fiber, calcium, iron compared to other fruits, fig have become an important source of diet to people especially in Mediterranean region since ancient time
Crowdfunding as Financial Option for Small and Medium Enterprises (SMEs) in Nigeria
Full text linkAbstract Small and medium scale enterprises (SMEs) act as a promoter of economic development of the developed and under developed nations. Developing countries like Nigeria that, require sustainable economic growth and development must pay attention to the SMEs sectors in order to reduce unemployment, poverty and improve the standard leaving of its society. Unfortunately, in Nigeria, SMEs have underperformed despite that, 90% of the Nigerian businesses are small scales but their contribution to the Nigerian GDP is below 10%. The main reason for this low contribution of SMEs to Nigerian GDP could be attributed to poor funding, lack of management expertise and lack of access to modern technology among others, with proper finance the SMEs can acquire modern technology and employed qualified staff. Thus, this paper focuses on crowdfunding as financial option for small and medium enterprises in Nigeria. However the paper is based on conceptual framework.
Syntactic Analysis of Newspaper Editorials: a Pilot Study
Full text linkThis study aimed to assess the feasibility of a syntactic analysis of newspaper editorials and to test out Morenberg’s (2010) syntactic theory. The purposes of this study hence, were to develop appropriate research questions and related plans as well as to find out whether Morenberg’s (2010) theory would be sufficient for the syntactic analysis of editorials. By adopting this theory, one editorial from The Star, Malaysia and two editorials from The Sun, UK were analysed, with the hope to not only put forth the concept of syntax, but also to highlight the dissimilar styles and constructions in professional writing. Sentences obtained from these three editorials were broken down via tree diagramming to answer research question one- what are the syntactic patterns used in editorials in newspapers? The tree diagrams of all sentences were then cross-examined to answer research question two- are there syntactic differences in editorials? The study found the basic patterns of the sentences of all editorials to be containing mostly transitive verbs, with the inclusion of many VBE verbs and very few incorporations of intransitive and Vc verbs. Optional elements in the syntactic patterns however, varied according to their different orders in sentence builds. Tree diagramming of the sentences revealed few noticeable differences in terms of sentence mood, structural parallelism, employment of wh-clause as well as subject ellipsis
Effect ofZingiber officinaleon Spasm
Full text linkZingiberaceae is one of the largest plant families consisting of rhizomes that are commonly used as spice in soups and curries as well as alternative medications in folklore medicine. Zingiber officinale or commonly known as ginger is extensively employed in Asian, Ayurvedic, Chinese, and Arabian folklore medicine for the treatment of pain, inflammation and various spasm-associated gastric ailments. The past few decades saw rapid advancements in the extraction process of ginger bioactive constituents and validation of their corresponding pharmacodynamic and pharmacotherapeutic activities, and biological properties in vivo and in vitro. Results reported from several biological studies on ginger showed that extracts and compounds from this tuberous rhizome exhibit antiemetic, anticancer, antipyretic, antispasmogenic and antimicrobial activities. This article reviews the effect of Zingiber officinale and its bioactive constituents on isolated organ preparations from several species of animals in view of its potential use as an alternative treatment for muscle spasms and common gastric ailments
In Vitro Regeneration of Bamboo Species
Full text linkThis review paper discussed about journals related to micropropagation of bamboo species. In recent years, the application of tissue culture technique like in vitro micropropagation has been used to meet the demands for bamboo products. In the past 30 years, protocols for micropropagation of various bamboo species have been established by researchers from all over the world. The controlling factors for cultures such as the explants, culture medium, carbon sources, combination and concentration of plant growth regulators and other additional additives are varied amongst. The controlling factors are crucial in developing successful regeneration protocols for various bamboo species. This paper is attempted to review and summarize the available and up to date information regarding in vitro micropropagation of bamboos
Review Article: Appropriate Hydrothermal Pretreatment of Oil Palm Biomass in Palm Oil Mill
Full text linkOil palm (Elaeis guineensis Jacq.) is one of the most planted trees in Malaysia for the palm oil production. Thus, solid biomass had been generated from this industry such as empty fruit bunch, shell, mesocarp fibre, frond and trunk produced that causes problematic to the nation and expected to escalate up to 85-110 million tonnes by 2020. Besides that, palm oil mill effluent and excessive steam also generated from the production of palm oil. In situ hydrothermal pretreatment means the utilisation of excessive steam produced by the oil palm mill and at the same time, generating value added product as well as reducing the biomass. Oil palm biomass is rich in lignocellulosic materials which comprised of lignin, hemicellulose and cellulose. Refinement of lignocellulosic from oil palm biomass can be utilised to form fermentable sugar, bioethanol and other potential chemicals. Recalcitrant property of lignocellulosic reduces the ability of enzymes to penetrate, thus pretreatment is required prior to hydrolysis process. Pretreatment can be either physical, chemical, biological or combined. In this review paper, three types of hydrothermal pretreatment were discussed as suitable in situ pretreatment process for oil palm biomass; in palm oil mill. The suitability was measured based on the availability of excess steam and energy in the mill. Furthermore, physicochemical pretreatment also facilitate the saccharification process, whereby it loosened the lignocellulose structure and increase the surface area. The effects and factors in choosing right pretreatment are highlighted in this paper
Critical Review on Factors That Influence Continuous Engagement Towards CCBT
Full text linkSubstance abuse is an epidemic that spreads among adults, adolescents and even children in Malaysia. Substance abuse is categorized as a mental disorder, whereby, Cognitive Behavioural Therapy (CBT) is an approach that provides face to face physiological therapy for patients could resolve this issue. Computerized Cognitive Behavioural Therapy (CCBT) is a progression of information technology that is provided for patients encounter substance abuse. CCBT is a computerized therapy conducted at patient’s own pace. Ensuring patient’s continuous engagement towards CCBT becomes an issue. Patients that experience early gains, loss of interest and improvement symptom would sign up for alternative services that eventually causes disengagement and dropout from CCBT program. Interface design for CCBT is known as one of the important elements that effects patient’s engagement along CCBT program. Therefore, in this study, influential factors regarding CCBT’s interface design was investigated, whereby, five prominent models was reviewed. Content analysis methodology was employed to discover influential factors regarding CCBT’s interface design. Four influential factors was discovered namely engagement, dropout, culture and interface. These factors are known to ensure patient’s continuous engagement towards CCBT program. CCBT’s interface design plays a vital role in delivering the therapy program. Indirectly, CCBT’s interface design plays an important role to ensure patient’s continuous engagement till the completion of CCBT program. Therefore, these factors would guide researcher, service provider, developers and clinicians in designing engaging interface for CCBT
Paternal Parenting Behaviour and Psychological Health of Adolescents
Full text linkPsychological health as one of the most crucial indicators of successful adolescents has received considerable attention in the literature. High prevalence rates of various psychological problems amongst adolescents emphasize the significance of identifying paternal parenting behaviour that may reduce the risk of these problems. However, little attention has been given to how fathers influence their adolescents’ psychological health, especially in an Asian context. To address this issue, this paper presents a thorough discussion of past literature related to paternal parenting behaviour and psychological health of adolescents. The discussion begins with a review related to psychological health, paternal parenting behaviour, and followed by the relationships between paternal parenting behaviour and psychological health. Based on the review of the literature, several research gaps will be addressed at the end of this paper