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Vasorelaxants Mechanisms of Estriol: Endothelium-Dependent and -Independent Pathways in an Ex Vivo Rat Aortic Model
This study investigated the vasorelaxant effects of estriol (E3) compared to estradiol (E2) in rat thoracic aortic rings, focusing on endothelium-dependent and independent mechanisms. Isolated aortic rings from Wistar rats, with or without endothelium, were pre-contracted with phenylephrine and subjected to cumulative concentration–response curves for E3 and E2. The involvement of endothelial nitric oxide synthase (eNOS), potassium channels, prostanoids, and calcium influx was assessed using pharmacological inhibitors (L-NAME, TEA, indomethacin) and depolarizing Ca²⁺-free solutions. E3 promoted concentration-dependent vasorelaxation, but with lower potency and efficacy than E2. In endothelium-intact preparations, the relaxation induced by E3 was significantly reduced by L-NAME and TEA, suggesting participation of nitric oxide and potassium channels in its mechanism. Indomethacin did not alter E3-induced relaxation, indicating no significant involvement of prostanoids. In depolarized, calcium-free conditions, both E3 and E2 attenuated CaCl₂-induced contractions, indicating endothelium-independent modulation of calcium influx. These results demonstrate that estriol induces vasorelaxation through multiple mechanisms, including the activation of eNOS, involvement of K⁺ channels, and inhibition of calcium entry. Despite its lower efficacy, E3 shares key signaling pathways with E2 and may represent a vascularly active alternative in hormone replacement therapy with potentially favorable safety profiles.Este estudo investigou os efeitos vasorrelaxantes do estriol (E3) em comparação ao estradiol (E2) em anéis de aorta torácica de ratos, com ênfase nos mecanismos dependentes e independentes do endotélio. Anéis aórticos isolados de ratos Wistar, com ou sem endotélio, foram pré-contraídos com fenilefrina e submetidos a curvas concentração–resposta cumulativas para E3 e E2. A participação da óxido nítrico sintase endotelial (eNOS), de canais de potássio, de prostanoides e do influxo de cálcio foi avaliada por meio do uso de inibidores farmacológicos (L-NAME, TEA, indometacina) e de soluções despolarizantes livres de Ca²⁺. O E3 promoveu vasorrelaxamento de forma dependente da concentração, porém com menor potência e eficácia em relação ao E2. Em preparações com endotélio íntegro, o relaxamento induzido pelo E3 foi significativamente reduzido por L-NAME e TEA, sugerindo a participação do óxido nítrico e dos canais de potássio em seu mecanismo de ação. A indometacina não modificou o relaxamento induzido por E3, indicando ausência de envolvimento relevante dos prostanoides. Em condições despolarizadas e isentas de cálcio, tanto E3 quanto E2 atenuaram as contrações induzidas por CaCl₂, revelando uma modulação endotelial-independente do influxo de cálcio. Esses resultados demonstram que o estriol induz vasorrelaxamento por meio de múltiplos mecanismos, incluindo a ativação da eNOS, o envolvimento de canais de K⁺ e a inibição da entrada de cálcio. Apesar de sua menor eficácia, o E3 compartilha vias de sinalização fundamentais com o E2 e pode representar uma alternativa vascularmente ativa na terapia de reposição hormonal, com potencial perfil de segurança favorável
Innovations in Environmental Risk Assessment and Life Cycle Analysis for Ecotourism Sustainability
The objective of this research is to come up with an integrated environmental framework that incorporates Environmental Risk Assessment (ERA) and Life Cycle Analysis (LCA) to improve ecotourism sustainability. It aims at bridging theoretical and practical approaches by incorporating digitalization, data-driven decision-making, and collaborative governance in the context of ecotourism. This study is qualitative and thematic merging research design from secondary data collected from previous literature. The paper presents five merging themes interconnected dimensions, digitalization of ERA, integration of LCA, data-driven decision support and predictive analysis, governance, collaboration and policy alignment, socio environmental and economic co benefits relate them to the major theoretical developments, such as the evolution of the Smart Ecotourism Sustainability Theory. The results show that sustainable ecotourism management is reinforced by environmental assessment tools and technological innovation, and the collaboration of policy makers. The suggested framework offers destination managers, policymakers, and tourism operators with a systematic framework to evaluate and improve ecotourism sustainability. This paper will add value to the existing body of literature on ecotourism sustainability because it provides an in-depth synthesis of ERA and LCA that shows how their combination contributes to theoretical knowledge as well as the practical implementation. The research creates a new interdisciplinary framework, which facilitates adaptive, technology-based, and governance-focused solutions to the sustainable development of ecotourism.The objective of this research is to develop an integrated environmental framework that combines Environmental Risk Assessment (ERA) and Life Cycle Analysis (LCA) to improve ecotourism sustainability. It aims at bridging theoretical and practical approaches by incorporating digitalization, data-driven decision-making, and collaborative governance in the context of ecotourism. This study is qualitative and thematic, merging a research design based on secondary data from previous literature. The paper presents five merging themes, interconnected dimensions, digitalization of ERA, integration of LCA, data-driven decision support and predictive analysis, governance, collaboration and policy alignment, and socio-environmental and economic co-benefits, and relates them to the significant theoretical developments, such as the evolution of the Smart Ecotourism Sustainability Theory. The results show that environmental assessment tools, technological innovation, and policymakers’ collaboration reinforce sustainable ecotourism management. The suggested framework offers destination managers, policymakers, and tourism operators a systematic framework to evaluate and improve ecotourism sustainability. This paper adds value to the existing body of literature on ecotourism sustainability by providing an in-depth synthesis of ERA and LCA that demonstrates how their combination contributes to theoretical knowledge and practical implementation. All data used in this study were derived from publicly available secondary sources, and no human participants or sensitive personal information were involved. The research develops a new interdisciplinary framework that facilitates adaptive, technology-based, and governance-focused solutions for sustainable ecotourism development.
Efeito Residual do Herbicida Glifosato sobre a Germinação de Sementes de Feijão em Condição de Campo e Ambiente Controlado
Beans are one of the most important food crops in Brazil; however, they have low average productivity, which may be associated with various factors, including the initial plant stand due to the negative effects of using pre-sowing herbicides, such as glyphosate. Given this, the present study aimed to evaluate, both under natural cultivation conditions (field) and controlled conditions (laboratory), the interference of residual glyphosate herbicide on the germination of black bean seedlings at different application intervals. The intervals evaluated were 21 (T1), 14 (T2), 7 (T3), and 0 days (T4) before sowing, in addition to the Control (TC), with no application. Germination Rate (GR), Emergence Speed (ES), and Emergence Speed Index (ESI) were analyzed. In the field, only VE showed a significant difference (TC, T2, T4 vs. T1, T3), suggesting the influence of environmental factors. In a controlled environment, the results showed a temporal effect, with T4 (application on the day of sowing) presenting the lowest values, with a significant reduction in all parameters, while TC and T1 (earlier application) stood out with the highest values, which allows us to infer a possible degradation of glyphosate over time and a reduction of its phytotoxic impact. It is concluded that applications close to sowing compromise germination, reinforcing the need for safe intervals.O glifosato geralmente resulta em baixo efeito residual no campo. No entanto, em condições específicas de ambiente controlado ou a campo, as doses podem ser determinantes e impactar na germinação e no desenvolvimento inicial de sementes de feijão. Diante do exposto, o presente estudo teve como objetivo avaliar, tanto em condições naturais de cultivo (campo), como em condições controladas (laboratório) a interferência do residual do herbicida glifosato sobre a germinação de plântulas de feijão preto em diferentes intervalos de aplicação. Foram avaliados os intervalos de 21 dias (T1), 14 (T2), 7 (T3) e 0 dias (T4) antes da semeadura, além do Controle (TC), sem aplicação. Analisou-se a Taxa de Germinação (TG), Velocidade de Emergência (VE) e Índice de Velocidade de Emergência (IVE). A campo, apenas VE apresentou diferença significativa (TC, T2, T4 vs. T1, T3), sugerindo influência de fatores ambientais, como a umidade do solo. Em ambiente controlado, os resultados evidenciaram efeito temporal, em que o T4 (aplicação no dia da semeadura) apresentou os menores valores, com redução significativa em todos os parâmetros, enquanto TC e T1 (aplicação mais antecipada) destacaram-se com os maiores valores, o que permite inferir uma possível degradação do glifosato ao longo do tempo e a redução do seu impacto fitotóxico. Conclui-se que aplicações próximas à semeadura comprometem a germinação, reforçando a necessidade de intervalos seguros.
Gestão Ambiental e a Educação Ambiental: O Papel do Conselho Consultivo em uma Unidade de Conservação Estadual
Environmental Management, the Management Plan, and Environmental Education play essential roles in the existence and permanence of Conservation Units (CUs), which are created to address environmental problems. From this perspective, Environmental Education (EE) shows that the more aware the community is of environmental issues, the better both individual and collective actions will be in response to the discussions and discourses that arise in social and political dynamics. Our objective is to discuss Environmental Management strategies aimed at educational processes within the Parque Estadual Matas do Segredo (Matas do Segredo State Park, PEMS). We analyzed the minutes of meetings related to the PEMS Advisory Council in order to understand the strategies adopted by its Environmental Management for the dissemination of Environmental Education at the UC. The research showed that, despite the challenges faced by the UC, the park has significant potential to establish itself as a sustainable educational space, thus helping to form citizens engaged in the protection and conservation of the environment.A Gestão Ambiental, o Plano de Manejo e a Educação Ambiental desempenham papéis necessários para a existência e permanência das Unidades de Conservação (UCs), que são criadas para minorar as problemáticas ambientais. Nessa perspectiva, a Educação Ambiental (EA) demonstra que quanto mais a coletividade estiver inteirada da problemática ambiental, melhor será a atuação individual e coletiva frente as discussões e discursos que se apresentam nas dinâmicas sociais e políticas. Desempenhando um papel importante no processo de busca por soluções viáveis e necessárias, o conselho consultivo vem para somar forças frente aos desafios socioambientais existentes, sendo uma das formas de se exercer a gestão ambiental participativa nas UCs. Tem por objetivo discutir as estratégias de Gestão Ambiental voltadas para os processos educativos no âmbito do Parque Estadual Matas do Segredo (PEMS). Por meio da categorização dos temas abordados nas reuniões do conselho consultivo e da triangulação desses dados, foi feita a análise das atas de reuniões ocorridas no PEMS, almejando compreender as estratégias adotadas pela Gestão Ambiental para a disseminação da Educação Ambiental na UC. A presente pesquisa evidenciou a dinâmica e atuação do conselho consultivo do PEMS, além de elucidar que mesmo diante dos desafios enfrentados pela UC, o parque tem grande potencial para se consolidar como um espaço educador sustentável, auxiliando deste modo, na formação de cidadãos engajados na proteção e conservação do meio ambiente
Administração Pública e a Gestão Território-Ambiental: O Caso do Município de Ipaba/MG
Throughout the history of administration theories, there has been an evolution of public administration models, starting with the patrimonial model, moving on to the bureaucratic model, then to the managerial one. Currently, a new way of managing public affairs is evolving - governance. Thus, documental, bibliographic and field research are used to investigate the models of public administration and governance in the Municipality of Ipaba/MG. It is perceived today that public governance consists of a set of good practices and openness to citizen participation in a system of participatory democracy that can influence public policies and social awareness and the citizen's sense of belonging, in order to make him to collaborate with the conservation of his city. However, it appears that public governance is almost non-existent in the administration of the Municipality of Ipaba / MG, given that throughout its existence and even before its emancipation, irregular land occupations had a decisive influence on its consolidation. and territorial-environmental management, adversely affecting the preservation of the environment and the city's structural planning.Houve, ao longo da história das teorias da administração, uma evolução dos modelos da administração pública, iniciando-se pelo modelo patrimonialista, passando-se ao burocrático, depois ao gerencial. Atualmente, vem-se evoluindo para uma nova forma de administrar a coisa pública - a governança. Assim, utiliza-se da pesquisa documental, bibliográfica e pesquisa de campo para averiguar os modelos de administração pública e a governança no Município de Ipaba/MG. Percebe-se hoje, que a governança pública consiste em um conjunto de boas práticas e abertura à participação do cidadão em um sistema de democracia participativa que pode influenciar as políticas públicas e a consciência social e a sensação de pertencimento do munícipe, a fim de fazê-lo colaborar com a conservação de sua cidade. No entanto, verifica-se que a governança pública é quase inexistente na administração do Município de Ipaba / MG, haja vista, que ao longo da sua existência e mesmo antes de sua emancipação, ocupações irregulares de terras, influenciaram de forma determinante em sua consolidação e gestão territorial-ambiental, afetando nocivamente a preservação do meio ambiente e o planejamento estrutural da cidade
Reverse Logistics in the Amazon: A Territorialized Conceptual Model and Guidelines for Regional Public Policies
The implementation of reverse logistics (RL) in Amazonian regions unfolds under institutional, operational, and social conditions that differ significantly from other contexts, influencing the feasibility of circular economy strategies. These territories are characterized by long distances, dispersed small municipalities, reliance on river transport routes, low institutional density, and marked socioeconomic vulnerability, which increase logistical costs and hinder coordination among actors. Despite conceptual advances in the field, analytical models capable of integrating these territorial specificities into RL arrangements remain limited. This article seeks to understand how territorial and institutional factors in the Southwestern Amazon shape the implementation of RL and, based on this analysis, to propose a territorialized conceptual model to guide public policies in peripheral contexts. The research adopts a qualitative, exploratory, and analytic approach, combining a systematic literature review, which resulted in the selection of 33 articles, with a documentary analysis of legal frameworks and management reports from the state of Acre covering the period from 2020 to 2024. The triangulation of theoretical, normative, and institutional evidence enabled the identification of recurrent analytical categories, subsequently organized into six dimensions and three integrated levels — structural, operational, and social, which underpin the proposed conceptual model. The results reveal that RL in the region is shaped by fragile institutional coordination, infrastructure limitations, low flow traceability, dependence on external funding, and restricted productive inclusion of waste pickers. Building on this diagnosis, the study presents a set of key performance indicators and structured guidelines to support the regional implementation of RL, encompassing governance, financing, infrastructure, organic waste valorization, and social participation. The territorialized conceptual model contributes by offering an integrated interpretation of RL in Amazonian states and by providing analytical and operational instruments to inform state plans, waste management policies (PEGIRs), and public policies aimed at circular economy initiatives and sustainable territorial reorganization.The implementation of reverse logistics (RL) in Amazonian regions unfolds under institutional, operational, and social conditions that differ significantly from other contexts, influencing the feasibility of circular economy strategies. These territories are characterized by long distances, dispersed small municipalities, reliance on river transport routes, low institutional density, and marked socioeconomic vulnerability, which increase logistical costs and hinder coordination among actors. Despite conceptual advances in the field, analytical models capable of integrating these territorial specificities into RL arrangements remain limited. This article seeks to understand how territorial and institutional factors in the Southwestern Amazon shape the implementation of RL and, based on this analysis, to propose a territorialized conceptual model to guide public policies in peripheral contexts. The research adopts a qualitative, exploratory, and analytic approach, combining a systematic literature review, which resulted in the selection of 33 articles, with a documentary analysis of legal frameworks and management reports from the state of Acre covering the period from 2020 to 2024. The triangulation of theoretical, normative, and institutional evidence enabled the identification of recurrent analytical categories, subsequently organized into six dimensions and three integrated levels — structural, operational, and social, which underpin the proposed conceptual model. The results reveal that RL in the region is shaped by fragile institutional coordination, infrastructure limitations, low flow traceability, dependence on external funding, and restricted productive inclusion of waste pickers. Building on this diagnosis, the study presents a set of key performance indicators and structured guidelines to support the regional implementation of RL, encompassing governance, financing, infrastructure, organic waste valorization, and social participation. The territorialized conceptual model contributes by offering an integrated interpretation of RL in Amazonian states and by providing analytical and operational instruments to inform state plans, waste management policies (PEGIRs), and public policies aimed at circular economy initiatives and sustainable territorial reorganization
Caracterização e Análise da Gestão Integral na Qualidade do Serviço Comprador e Fornecedor na Cadeia de Tilápia no Distrito Federal - Brasil
Within the agribusiness sector, this research aims to help Brazil reach 4th place in the world ranking of the largest producers of this species. Due to the significant importance of the species and the potential consumer market for fish, this study analyzes the buyer-supplier relationship in the quality management of tilapia consumed in the Federal District. This research is characterized as applied and descriptive and uses qualitative research resources. As a research method, 12 semi-structured interviews were conducted in fish markets and restaurants in the Federal District. Subsequently, triangulation was performed between the interview data and data from previously obtained non-participant observation scripts of a face-to-face nature. The results indicate that a successful partnership, from the buyers' point of view, is highly influenced by trust, commitment, and communication, leading buyers to be satisfied with the relationship and want to maintain a long-term relationship with their main tilapia supplier.Dentro do agronegócio, para que o Brasil alcance o 4º lugar no ranking mundial dos maiores produtores desta espécie. Devido à significativa importância da espécie e ao potencial mercado consumidor de pescado, esta pesquisa analisa a relação comprador-fornecedor na gestão da qualidade da tilápia consumida no Distrito Federal. Esta pesquisa caracteriza-se como aplicada e descritiva e faz uso de recursos de pesquisa qualitativa. Como método de pesquisa, aplicou-se 12 entrevistas semiestruturadas em peixarias e restaurantes no Distrito Federal, em seguida promoveu-se a triangulação entre os dados das entrevistas e os dados dos roteiros de observação não participante de caráter presencial, previamente obtidos. Os resultados indicam que uma parceria bem-sucedida, do ponto de vista dos compradores, é altamente influenciada quando existe confiança, compromisso e comunicação, fazendo com que os compradores se tornem satisfeitos com a relação e queiram manter um relacionamento a longo prazo com o seu principal fornecedor de tilápia
Evolução da Gestão dos Resíduos Sólidos no Âmbito da Gestão Ambiental do Município de Aracati – CE
Solid waste management represents one of the greatest environmental challenges, especially in small and medium-sized municipalities, due to financial and structural limitations. This study aimed to analyze the evolution of environmental management in the municipality of Aracati, Ceará, Brazil, with an emphasis on solid waste management. A bibliographic review was conducted, supported by official documents, municipal and state legislation, and publications from governmental agencies. Data collection took place between May 2019 and July 2020.The results indicate that, although Aracati has a significant set of laws and initiatives aimed at environmental protection, including the creation of municipal policies and awareness programs, the effectiveness of these actions remains limited. The municipality lacks a Municipal Solid Waste Management Plan, does not implement selective waste collection, has no sanitary landfill, and continues to use an open-air dump as the final destination for waste, which is inconsistent with the National Solid Waste Policy (PNRS). Despite regulatory advances between 2017 and 2019, there is a clear gap between legislation and its practical implementation, highlighting the need for integrated actions and investments to align local management with national environmental standards.A gestão de resíduos sólidos representa um dos maiores desafios ambientais, especialmente em municípios de pequeno e médio porte, devido à limitação de recursos financeiros e estruturais. Este estudo teve como objetivo analisar a evolução da gestão ambiental no município de Aracati – CE, com ênfase no gerenciamento de resíduos sólidos. Para isso, foi realizado um levantamento bibliográfico, consulta a documentos oficiais, legislações municipais e estaduais, bem como publicações de órgãos governamentais, com coleta de dados entre maio de 2019 e julho de 2020.Os resultados indicam que, embora Aracati possua um conjunto significativo de leis e iniciativas voltadas à proteção ambiental, incluindo a criação de políticas municipais e programas de conscientização, a efetividade dessas ações ainda é limitada. O município não dispõe de Plano Municipal de Resíduos Sólidos, não executa coleta seletiva, não possui aterro sanitário e ainda utiliza lixão a céu aberto como destino final dos resíduos, em desacordo com a Política Nacional de Resíduos Sólidos (PNRS). Apesar de avanços normativos ocorridos entre 2017 e 2019, observa-se uma lacuna entre a legislação e sua aplicação prática, evidenciando a necessidade de ações integradas e investimentos para adequar a gestão local aos padrões ambientais estabelecidos
A Percepção Multiprofissional sobre Cuidados Paliativos em UTI durante a Pandemia de COVID-19: Uma Reflexão Bioética
The COVID-19 pandemic presented unprecedented clinical, ethical, and organizational challenges to healthcare professionals, particularly in Intensive Care Units (ICUs). This qualitative and exploratory field study aimed to understand the perception of the multidisciplinary team (physicians, nurses, physiotherapists) in a university ICU regarding the promotion of palliative care during the pandemic, informed by principlist bioethics. Findings revealed intense physical, emotional, and moral overload, exacerbated by resource scarcity, lack of protocols, and insufficient palliative care training, impacting care quality and the application of bioethical principles. Family communication was a fragile point, remotely mediated and lacking connection. Shared decision-making, though conceptually valued, was undermined by practical obstacles. Palliative care was often narrowly associated with terminality, reinforcing stigmas. Nevertheless, ethical virtues like compassion and responsibility emerged, sustaining patient dignity. The study underscores the urgent need for public and institutional policies integrating palliative care into ICUs, with ethical and technical training, advance planning, and valuing listening.A pandemia de COVID-19 impôs desafios clínicos, éticos e organizacionais sem precedentes aos profissionais de saúde, especialmente nas Unidades de Terapia Intensiva (UTIs). Este estudo de campo qualitativo e exploratório objetivou compreender a percepção da equipe multiprofissional (médicos, enfermeiros, fisioterapeutas) de uma UTI universitária sobre a promoção de cuidados paliativos durante a pandemia, sob a ótica da bioética principialista. Os resultados revelaram intensa sobrecarga física, emocional e moral, exacerbada pela escassez de recursos, ausência de protocolos e capacitação insuficientes em cuidados paliativos, impactando a qualidade da assistência e a aplicação dos princípios bioéticos. A comunicação com familiares foi identificada como um ponto frágil, mediada remotamente e carente de vínculo. A tomada de decisão compartilhada, embora valorizada, foi comprometida por entraves práticos. Observou-se uma associação restrita dos cuidados paliativos à terminalidade, reforçando estigmas. Contudo, virtudes éticas como compaixão e responsabilidade emergiram, sustentando a dignidade dos pacientes. A pesquisa destaca a urgência de políticas públicas e institucionais que integrem sistematicamente os cuidados paliativos às UTIs, com formação ética e técnica, planejamento antecipado e valorização da escuta
Interferência da Mato-Competição no Cultivo do Maracujazeiro: Fatores Determinantes do Crescimento sob Estresse Hídrico e Nutricional na Baixada Fluminense
Yellow passionfruit (Passiflora edulis) accounts for 90% of Brazil’s national production, yet its shallow root system makes it highly vulnerable to weed competition. This study evaluated the effects of Panicum maximum interference, water stress, and nutrient limitation on passionfruit seedling growth under greenhouse conditions. A 2×2×2 factorial design was used, with treatments combining presence/absence of weeds, water restriction (50% vs. 80% field capacity), and nutrient limitation (25% vs. 200% recommended fertilization). Soil moisture was monitored via pot weighing, and growth parameters were assessed. Results demonstrated that weed competition significantly reduced passionfruit development, particularly under concurrent water and nutrient stress. Seedlings in weed-free treatments with adequate resources (200% nutrients, 80% field capacity) showed 40% greater biomass compared to stressed conditions. Water limitation alone reduced leaf area by 30%, while nutrient restriction alone impaired root growth by 25%. The combined stress of weeds, low water, and low nutrients led to a 60% decline in overall plant vigor, highlighting synergistic negative effects. These findings emphasize the critical need for weed control during orchard establishment, especially in resource-limited regions like Baixada Fluminense. Optimizing irrigation and fertilization can mitigate weed interference, enhancing passionfruit productivity. This study provides actionable insights for tropical fruit farming and aligns with global goals for sustainable agriculture.O maracujá-amarelo (Passiflora edulis) responde por 90% da produção nacional brasileira, porém seu sistema radicular superficial o torna altamente vulnerável à competição com plantas daninhas. Este estudo avaliou os efeitos da interferência do capim-colonião (Panicum maximum), estresse hídrico e limitação nutricional no crescimento de mudas de maracujazeiro em condições de casa de vegetação. Utilizou-se delineamento fatorial 2×2×2, combinando presença/ausência de plantas daninhas, restrição hídrica (50% vs. 80% da capacidade de campo) e limitação nutricional (25% vs. 200% da adubação recomendada). A umidade do solo foi monitorada por pesagem dos vasos e parâmetros de crescimento foram avaliados. Os resultados demonstraram que a competição com plantas daninhas reduziu significativamente o desenvolvimento do maracujazeiro, especialmente sob estresse hídrico e nutricional combinados. Mudas em tratamentos sem plantas daninhas e com recursos adequados (200% de nutrientes, 80% de capacidade de campo) apresentaram 40% mais biomassa que as sob condições estressantes. A limitação hídrica isolada reduziu a área foliar em 30%, enquanto a restrição nutricional isolada prejudicou o crescimento radicular em 25%. O estresse combinado de plantas daninhas, baixa disponibilidade hídrica e nutricional resultou em 60% de declínio no vigor geral das plantas, evidenciando efeitos sinérgicos negativos. Estes resultados destacam a necessidade crítica do controle de plantas daninhas durante o estabelecimento de pomares, especialmente em regiões com limitação de recursos como a Baixada Fluminense. A otimização da irrigação e adubação pode mitigar a interferência de plantas daninhas, aumentando a produtividade do maracujazeiro. Este estudo fornece subsídios importantes para a fruticultura tropical e alinha-se com os objetivos globais de agricultura sustentável