98 research outputs found
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Effects and underlying mechanisms of unstable shoes on chronic low back pain : a randomized controlled trial / Juan Francisco Lisón ... [et al.].
No full textEste artículo se encuentra disponible en la página web de la revista en la siguiente URL: https://journals.sagepub.com/doi/abs/10.1177/0269215517753972?rfr_dat=cr_pub%3Dpubmed&url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&journalCode=creaEste es el postprint del siguiente artículo: Lisón, JF., Ortega-Santana, B., Antón-Nogués, Á., González-Requena, P., Vera-Hervás, C., Doménech-Fernández, J. et al. (2018). Effects and underlying mechanisms of unstable shoes on chronic low back pain : a randomized controlled trial. Clinical Rehabilitationol. 32, n. 5 (may), pp. 654-662, que se ha publicado de forma definitiva en https://doi.org/10.1177/0269215517753972This is the pre-peer reviewed version of the following article: Lisón, JF., Ortega-Santana, B., Antón-Nogués, Á., González-Requena, P., Vera-Hervás, C., Doménech-Fernández, J. et al. (2018). Effects and underlying mechanisms of unstable shoes on chronic low back pain : a randomized controlled trial. Clinical Rehabilitationol. 32, n. 5 (may), pp. 654-662, which has been published in final form at https://doi.org/10.1177/0269215517753972Objective: To investigate the effects that wearing unstable shoes has on disability, trunk muscle activity, and lumbar spine range of motion (ROM) in patients with chronic lower back pain (CLBP).
Design: Randomized controlled trial.
Setting: Orthopedic Surgery Service.
Participants: We randomized 40 adults with nonspecific CLBP either to an unstable shoes group (n = 20) or to the control group (n = 20).
Intervention: The participants in the unstable shoes group were advised to wear these shoes for a minimum of six hours a day for four weeks. Control group participants were asked to continue wearing their regular shoes.
Outcome measures: Our primary outcome was measurement of back-related dysfunction, assessed using the Roland-Morris Disability Questionnaire. Secondary outcomes included changes in
electromyographic (EMG) activity of erector spinae (ES), rectus abdominis (RA), internus obliquus (IO), and externus obliquus (EO) muscles, and changes in lumbar spine ROM.
Results: Between-group analysis highlighted a significant decrease in disability in the unstable shoes group compared to the control (−5, 95% confidence interval (CI) = −8.4 to −1.6). Our results revealed a significant increase in the percentage of RA, ES, IO, and EO EMG activity and in lumbar spine ROM in the unstable shoes group compared to the control group. Moreover, our results showed a significant negative correlation between disability and the percentage of ES, RA, and IO muscle activity at the end of the intervention.Este trabajo ha sido financiado por la Universidad CEU Cardenal Herrera (INDI 16/35) y el Instituto de Salud Carlos III, España (PI12/02710).UCH. Financiación Nacional / UCH. Financiación UniversidadPostprin
Effects of morphine-alfaxalone-midazolam premedication, alfaxalone induction and sevoflurane maintenance on intraocular pressure and tear production in dogs / A. Mayordomo-Febrer ... [et al.].
No full textEste artículo se encuentra disponible en la página web de la revista en la siguiente URL: https://veterinaryrecord.bmj.com/content/vetrec/180/19/474.full.pdfThis is the pre-peer reviewed version of the following article: Mayordomo-Febrer, A., Rubio-Zaragoza, M., Martínez-Gassent, M. & López-Murcia, MM. (2017). Effects of morphine-alfaxalone-midazolam premedication, alfaxalone induction and sevoflurane maintenance on intraocular pressure and tear production in dogs. Veterinary Record, vol. 180, n. 19 (13 may), art. 474, which has been published in final form at http://dx.doi.org/10.1136/vr.104040Este es el pre-print del siguiente artículo: Mayordomo-Febrer, A., Rubio-Zaragoza, M., Martínez-Gassent, M. & López-Murcia, MM. (2017). Effects of morphine-alfaxalone-midazolam premedication, alfaxalone induction and sevoflurane maintenance on intraocular pressure and tear production in dogs. Veterinary Record, vol. 180, n. 19 (13 may), art. 474, que se ha publicado de forma definitiva en http://dx.doi.org/10.1136/vr.104040Intraocular pressure (IOP) and tear production are ocular parameters commonly affected by general anaesthesia. A good control of both of them is necessary to guarantee a successful ophthalmic surgery. The purpose of this research was to analyse the effect of a common anaesthetic protocol based on morphine-alfaxalone-midazolam premedication, alfaxalone induction and sevoflurane maintenance on IOP and Schirmer tear test (STT-1) in healthy dogs. Twenty two adult mixed dogs scheduled for an ovariohysterectomy were used for this study. IOP and STT-1 were registered at baseline (T0), 5 (T1), 10 (T2) and 15 (T3) minutes after premedication with morphine-alfaxalone-midazolam combination; after induction (T4) with alfaxalone and 15 (T5) and 25 (T6) minutes after maintenance with sevoflurane. A paired Student´s t-test and a Wilcoxon test were used to analyse the difference between IOP and STT-1 over time respectively. This anaesthetic protocol produced a statistically significant increase in IOP (P<0.05) after premedication and induction, which was maintained after intubation. STT-1 showed a severe significant reduction during all the procedure (P<0.001). These conclusions should be taken into consideration, especially in dogs with damaged corneas, those predisposed to glaucoma and those who will be undergoing intraocular surgery. Ocular lubrication is necessary if this protocol is used.Preprin
III Seminario de Teoría y Filosofía Política : memoria de la actividad
No full textEl auge de la sociedad y de la comunicación de masas en la década de los 20 del siglo pasado trajo consigo una crisis de la concepción ilustrado-liberal de la democracia. Por un lado, ese auge habría provocado un incremento de las conductas no racionales en la sociedad, suscitando con ello una crisis del ideal universalizable del sujeto/ciudadano agente racional ilustrado. Por otro lado, y en conexión con lo anterior, entró también en crisis la creencia en que existe un público interesado, informado y capaz de formar una opinión pública que dirija/vigile la acción pública, algo que la realidad efectiva de la práctica periodística de aquel momento pareció encargarse de ratificar. Este seminario se dedica a examinar aquel momento de crisis, analizando diversas circunstancias y propuestas de la época, y con la mirada puesta en las lecciones que ese momento histórico puede ofrecer para nuestro presente.Esta actividad se inclueyo dentro del proyecto de I+D+i del MINECO “Crisis y relectura del liberalismo en el periodo de entreguerras (1920-1938): las aportaciones de Walter Lippmann y José Ortega y Gasset” (FFI2013-42443-R) y del proyecto de investigación de la Universidad CEU Cardenal Herrera “Democracia deliberativa: fundamentos normativos,
implementación práctica y autorregulación” (INDI 16/01)
Quality of life, well-being and values in older people
No full textEn: Revista Clínica Contemporánea. ISSN 1989-9912 n. 8, e1, (2017), p. 1-1
Transmedia narratives and advertising : analysis of the most awarded campaigns (2011-2016)
No full textEste artículo se encuentra disponible en la página web de la revista en la siguiente URL: http://www.adcomunicarevista.com/ojs/index.php/adcomunica/article/view/412/359Este número lleva por título "Transmedia y comunicación publicitaria: retos, narrativas y emociones".Los objetivos de la presente propuesta pueden ser resumidos como sigue:
1. Comprobar si, entre las campañas más galardonadas durante los últimos
seis años en los principales festivales, podemos encontrar campañas que
merezcan ser consideradas transmedia.
2. Establecer una escala para medir el grado de transmedialidad y el de
interacción con los usuarios en las campañas analizadas.
Nuestra hipótesis es que la narrativa transmedia todavía no está presente como rasgo distintivo y significativo dentro de los discursos publicitarios. Para el trabajo de campo hemos recurrido a una metodología que hibrida lo cuantitativo y cualitativo. Los resultados se han obtenido mediante el análisis de contenido con la identificación de los parámetros básicos que dan cuenta de la transmedialidad y la interacción. El corpus a analizar ha sido extraído de los palmarés de los principales festivales publicitarios desde 2011 a 2016, centrándonos en los grandes premios y los galardones de oro en las categorías de campañas integradas y/o interactivas. De los resultados del análisis se ha confirmado que, aunque cada vez las campañas integran más medios, las condiciones que caracterizan
una campaña conceptualizada como transmedia se dan en una minoría de las campañas premiadas. Concluyendo, por tanto, que el carácter transmedia no es en la evolución de los últimos seis años un valor para los creativos publicitarios.The objectives of this work can be summarized as follows:
1. To check if among the most awarded campaigns during the last six years
in the main advertising festivals we can find campaigns that deserve to
be considered transmedia examples.
2. to establish a scale to measure the degree of transmedia and the interaction with users in the campaigns analyzed.
Our hypothesis is that transmedia narratives are not yet present as a distinctive and significant feature in most of advertising campaigns.To go deeper on this subject we have applied a methodology that hybridizes the quantitative and the qualitative. The results were obtained through the content analysis with the identification of the basic parameters that must be present in a transmedia advertising campaign and measuring interaction with users. The corpus to analyze has been extracted from the awards of the main advertising festivals from 2011 to 2016 focusing on the Grand Prix and the Gold Awards in the categories of integrated and / or interactive campaigns. From the results of the analysis it has been confirmed that, although the campaigns are more and more integrated, the conditions that characterize a campaign conceptualized as transmedia occur in a minority of the winning campaigns. Concluding, therefore, that the transmedia
parameters are not a value for the advertising creatives in the evolution
of the last six years
Pirating conserved phage mechanisms promotes promiscuous staphylococcal pathogenicity island transfer / Janine Bowring ... et al.
No full textEste artículo se encuentra disponible en la página web de la revista en la siguiente URL: https://elifesciences.org/articles/26487Targeting conserved and essential processes is a successful strategy to combat enemies. Remarkably, the clinically important Staphylococcus aureus pathogenicity islands (SaPIs) use this tactic to spread in nature. SaPIs reside passively in the host chromosome, under the control of the SaPI-encoded master repressor, Stl. It has been assumed that SaPI de-repression is effected by specific phage proteins that bind to Stl, initiating the SaPI cycle. Different SaPIs encode different Stl repressors, so each targets a specific phage protein for its de-repression. Broadening this narrow vision, we report here that SaPIs ensure their promiscuous transfer by targeting
conserved phage mechanisms. This is accomplished because the SaPI Stl repressors have acquired different domains to interact with unrelated proteins, encoded by different phages, but in all cases performing the same conserved function. This elegant strategy allows intra- and inter-generic SaPI transfer, highlighting these elements as one of nature’s most fascinating subcellular parasites.Este trabajo ha sido subvencionado por la ayuda BIO2013-42619-P y BIO2016-78571-P del Ministerio de Economia y Competitividad (España) y la ayuda Prometeo II/2014/029 de la Generalitat Valenciana (España), y las ayuda MR/M003876/1 del Medical Research Council (UK), BB/N002873/1 del Biotechnology and Biological Sciences Research Council (BBSRC, UK), 201531/Z/16/Z del Wellcome Trust y ERC-ADG-2014 Proposal n° 670932 Dut-signal (de la EU). La investigación que condujo a estos resultados ha recibido financiación del Séptimo Programa Marco de la Comunidad Europea (7PM / 2007-2013) en virtud de BioStruct-X (acuerdo de subvención N ° 283570)
Freedom of speech (in War Time) : an approach from a text by Zechariah Chafee
No full textEste artículo se encuentra disponible en la siguiente URL: https://www.unav.edu/publicaciones/revistas/index.php/persona-y-derecho/article/view/8367/8247El presente estudio explora la regulación que la Espionage Act estadounidense de 1917 realiza del derecho humano a la libertad de expresión, de la mano de un texto de Zechariah Chafee que abordó la aplicación inicial de esa ley. A juicio de Chafee, la consagración de la libertad de expresión en la Primera Enmienda de la Constitución
americana no impide que los poderes ejecutivo y legislativo puedan establecer legítimamente ciertas medidas en tiempo de guerra conducentes a limitarla. Con todo, tanto la redacción como la interpretación de esas medidas deben alejarse del empleo de las doctrinas de la causación
indirecta y de la intención implícita, que nunca son adecuadas para determinar si una afirmación debe ser amparada (algo que no tuvo en cuenta la reforma de la Espionage Act de 1918, ni la mayor parte de la jurisprudencia del momento). Para Chafee, la libertad de expresión debe quedar desprovista de censura y de posterior sanción salvo que dé claramente lugar a una interferencia directa y peligrosa en relación al curso de la guerra.The present study deals with the human right to freedom of speech as regulated in the Espionage Act of 1917. The study relies mostly in a text by Zechariah Chafee which analyzes the Act’s early application. To Chafee’s
mind, the fact that the First Amendment of the U.S. Constitution consecrates freedom of speech should not prevent neither the Government nor the legislative power from stablishing certain limiting measures to it. However,
both the wording and the interpretation of these measures must stay away from the doctrines of indirect causation and constructive intent, which are never appropriate in order to stablish whether a statement should be protected or not as freedom of speech (the reform of the Espionage
Act in 1918 did not respect this boundary, and the majority of the American courts at the time went along the same path). In Chafee’s view, speech should be unrestricted from censorship or punishment unless it is clearly
liable to cause a direct and dangerous interference with the conduct of war.Este trabajo se enmarca en el Proyecto de investigación "Crisis y relectura del liberalismo en el período de entreguerras (1920-1938): las aportaciones de Walter Lippmann y José Ortega y Gasset", financiado a través del Programa Nacional de I+D+i del Ministerio de Economía y Competitividad (FFI2013-42443-R).UCH. Financiación Naciona
Biomechanic characteristics of gait of four breeds of dogs with different conformations at walk on a treadmill / José M. Vilar ... [et al.].
No full textEste artículo se encuentra disponible en la siguiente URL: https://www.tandfonline.com/doi/full/10.1080/09712119.2015.1031778Principle of ‘dynamic similarity’ is frequently applied in biomechanic research as a tool to extrapolate data between animals from the same species, but, in dogs, different breeds entail different conformations. For that reason, comparison of dynamic parameters among dogs of different breeds should not be only based in weight and relative velocity. By means of the use of force platform and high-speed videography in 12 dogs corresponding with four breeds of different conformations, we showed how most of kinetic and kinematic variables are highly independent of weight or relative
velocity and other factors as morphometric values and ratios are determinant
IV International Course of Orbitoplastic Surgery in Amalfi Coast
No full textEste libro se encuentra disponible en la siguiente URL: http://www.colangeloluigi.com/files/pdf-abstract-poster.pd
Looking into aqueous humor through metabolomics spectacles - exploring its metabolic characteristics in relation to myopia / Cecilia Barbas-Bernardos ... [et al.].
No full textEste es el post-print que se ha publicado de forma definitiva en: hhttps://www.sciencedirect.com/science/article/abs/pii/S0731708516301509Aqueous humor is the transparent fluid found in the anterior chamber of the eye that provides the metabolic requirements to the avascular tissues surrounding it. Despite the fact that metabolomics could be a powerful tool in the characterization of this biofluid and in revealing metabolic signatures of common ocular diseases such as myopia, it has never to our knowledge previously been applied in humans. In this research a novel method for the analysis of aqueous humor is presented to show its application in the
characterization of this biofluid using CE–MS. The method was extended to a dual platform method (CE–MS and LC–MS) in order to compare samples from patients with different severities of myopia in order to explore the disease from the metabolic phenotype point of view. With this method, a profound knowledge of the metabolites present in human aqueous humor has been obtained: over 40 metabolites were reproducibly and simultaneously identified from a low volume of sample by CE–MS, including among others, a vast number of amino acids and derivatives. When
this method was extended to study groups of patients with high or low myopia in both CE–MS and LC–MS, it has been possible to identify over 20 significantly different metabolite and lipid signatures that distinguish patients based on the severity of myopia. Among these, the most notable higher abundant metabolites in high myopia were aminooctanoic acid, arginine, citrulline and sphinganine while features of low myopia were aminoundecanoic acid, dihydro-retinoic acid and cysteinylglycine disulfide.
This dual platform approach offered complementarity such that different metabolites were detected in each technique. Together the experiments presented provide a whelm of valuable information about human aqueous humor and myopia, proving the utility of non-targeted metabolomics for the first time in analyzing this type of sample and the metabolic phenotype of this disease.Este artículo ha sido subvencionado por el Ministerio de Ciencia y Tecnología del Gobierno de España CTQ2014-55279-R y por la Generalitat Valenciana APM-05/15, además de una ayuda PRCEU-UCH CON-15/05 (CEU – Banco Santander).UCH. Financiación Nacional / UCH. Financiación Autonómica / UCH. Financiación UniversidadEste es el post-print del siguiente artículo: Barbas-Bernardos, C., Armitage, EG., García, A., Mérida, S., Navea, A., Bosch-Morell, F. et al. (2016). Looking into aqueous humor through metabolomics spectacles - exploring its metabolic characteristics in relation to myopia. Journal of Pharmaceutical and Biomedical Analysis, vol. 127, pp. 18-25, que se ha publicado de forma definitiva en https://doi.org/10.1016/j.jpba.2016.03.032This is the peer reviewed version of the following article: Barbas-Bernardos, C., Armitage, EG., García, A., Mérida, S., Navea, A., Bosch-Morell, F. et al. (2016). Looking into aqueous humor through metabolomics spectacles - exploring its metabolic characteristics in relation to myopia. Journal of Pharmaceutical and Biomedical Analysis, vol. 127, pp. 18-25, which has been published in final form at https://doi.org/10.1016/j.jpba.2016.03.03