Universidad Nacional de Trujillo: Publicaciones Científicas
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Medicina del estilo de vida: Perspectiva de una necesidad en salud. Revisión
Full text linkGlobally, the main causes of mortality and disability are associated with non-communicable chronic diseases (NCDs), and unhealthy lifestyle are a modifiable risk factor for acquiring these diseases. Adherence to a healthy lifestyle can prevent, treat, and reverse, with a lower cost and greater long-term benefit, the effects of NCDs. Lifestyle Medicine (LM) is a discipline focused on healthy lifestyle, which has been positioning itself in the reality and its introduction into undergraduate medical training, postgraduate training, and continuing medical education is already taking place mainly in the United States of America and Europe. A review of the databases PubMed/Medline, Web of Science, Scopus and Google Scholar was carried out, with the purpose of documenting a perspective of what the LM is, its effects, forms of application and recent results of its implementation in the health. LS offers a cost-benefit alternative to prevent, treat and reverse NCDs.A nivel global, las principales causas de mortalidad y discapacidad están asociadas a enfermedades crónicas no transmisibles (ECNT), y el estilo de vida no saludable son un factor de riesgo modificable para adquirir estas enfermedades. La adherencia a un estilo de vida saludable puede prevenir, tratar y revertir, con un menor costo y mayor beneficio a largo plazo, los efectos de las ECNT. La Medicina del Estilo de Vida (MEV) es una disciplina centrada en el estilo de vida saludable, que se ha ido posicionando en la realidad antes mencionada y su introducción en la formación médica del pregrado, postgrado y educación médica continua ya se está llevando a cabo principalmente en Estados Unidos de América y Europa. Se realizó una revisión de las bases de datos PubMed/Medline, Web of Science, Scopus y Google Scholar, con la finalidad de documentar una perspectiva de lo que es la MEV, sus efectos, formas de aplicación y resultados recientes de su implementación en la salud. La MEV ofrece una alternativa costo beneficio para prevenir, tratar y revertir las ECNT
On the structure of the fundamental étale group of normal schemes
Full text linkThe étale fundamental group is a central tool in algebraic geometry that generalizes the topological fundamental group to the context of schemes. In this article, we explore its behavior for normal schemes, highlighting its relationship to arithmetic and geometric invariants.El grupo fundamental étale es una herramienta central en geometría algebraica que generaliza el grupo fundamental topológico al contexto de esquemas. En este artículo, exploramos su comportamiento para esquemas normales, destacando su relación con invariantes aritméticos y geométricos.The étale fundamental group is a central tool in algebraic geometry that generalizes the topological fundamental group to the context of schemes. In this article, we explore its behavior for normal schemes, highlighting its relationship to arithmetic and geometric invariants
Fatou’s Theorem; its contribution to harmonic analysis
Full text linkThe objective of this article is to see how Fatou’s theorem, given at the beginning of the 20th century, motivated new developments in harmonic analysis and partial differential equations in the second half of that century. In this writing we give a brief tour of some of the contributions given by distinguished analysis and in this way our interest is to make such progress known in Peru and thus contribute to the development of this beautiful branch of mathematical analysis, which we believe is almost unknown in our country. In particular we have paid some attention to the work of Jerison - Kenig [1] because such work contains an overview that helps meet our objective.El objetivo de este artículo es ver como el teorema de Fatou, dado a inicios del siglo XX, motivó nuevos desarrollos en el análisis armónico y en las ecuaciones en derivadas parciales en la segunda mitad de tal siglo. En este escrito damos un breve recorrido por algunas de las contribuciones dadas por distinguidos analistas y de esta manera nuestro interés es dar a conocer en el Perú tales progresos y así contribuir con el desarrollo de esta bella rama del análisis matemático, que creemos es casi desconocida en nuestro país. En particular hemos puesto cierta atención al trabajo de Jerison - Kenig [1], por contener tal trabajo un panorama que ayuda a cumplir con nuestro objetivo.The objective of this article is to see how Fatou’s theorem, given at the beginning of the 20th century, motivated new developments in harmonic analysis and partial differential equations in the second half of that century. In this writing we give a brief tour of some of the contributions given by distinguished analysis and in this way our interest is to make such progress known in Peru and thus contribute to the development of this beautiful branch of mathematical analysis, which we believe is almost unknown in our country. In particular we have paid some attention to the work of Jerison - Kenig [1] because such work contains an overview that helps meet our objective
A ficitionalist approach to the ontology of mathematics
Full text linkMathematics is defined as the study and development of conceptual interpreted formal systemsthat are closed by deduction. These systems are not merely syntactic in the manner of logisticsystems. They are interpreted, but their reference class is constituted by conceptual artifacts.Mathematical constructs are human-made creations that exist solely within the context of a specificformal system. Consequently, mathematics is devoid of any ontological import. The referents ofmathematics cannot exist independently of the human mind. The theory is consistent with anygeneral materialist worldview
Limitación de una generalización euclidiana en la historia: ángulos interiores del triángulo esférico
Full text linkAnte la necesidad de tratar con las generalizaciones euclidianas, en este documento se presenta un estudio histórico-epistemológico desde la Socioepistemología, que a través de un análisiscualitativo de contenidos busca identificar y caracterizar prácticas matemáticas asociadas a la generalización euclidiana, la suma de los ángulos interiores de un triángulo esférico, en la génesis dela geometría esférica, de tal forma que estas prácticas sirvan para configurar un posicionamientoepistemológico inicial para el diseño didáctico. Como resultado, se reconoce la influencia de loscambios políticos, económicos, culturales y científicos de la cultura del autor en la construccióny estructura de la actividad matemática; además, en términos epistemológicos, esta geometría secaracteriza por propiedades como la relación de divergencia-convergencia entre rectas, consecuenciade la articulación de varias prácticas matemáticas
Curcumina en la bioquímica del síndrome metabólico: Una revisión bibliográfica
No full textMetabolic syndrome has been developing over the years, affecting a significant percentage of the population, thus increasing the probability of developing more severe pathologies. In this situation, curcumin, a compound belonging to turmeric, stands out for its health benefits, by counteracting the effects of metabolic syndrome by regulating key enzymes in related biochemical pathways, such as glycolysis, lipolysis, lipogenesis, among others; as well as, with the reduction of oxidative stress and inflammation. Together, these long-term benefits reduce or reverse the progress of metabolic syndrome towards a more serious condition. Multiple studies, including randomized clinical studies and other bibliographic reviews, have verified the effectiveness of curcumin against different alterations, having positive results. Furthermore, recent research, including clinical studies in humans and animals, have shown that curcumin is not toxic, since even at high doses it does not produce significant alterations. On the contrary, brings benefits to the human lifestyle. While more studies are needed to better understand the full effects of curcumin. Even so, it is promising as a chemopreventive agent against the development of metabolic syndrome and its sequelae, as long as, curcumin and its derivatives are integrated as part of the components of future medications or treatments in different diseases, especially metabolic syn.El síndrome metabólico ha venido desarrollándose a lo largo de los años afectando a un porcentaje significativo de la población, aumentando así las probabilidades de desarrollar patologías más severas. Ante esta situación, la curcumina, un compuesto perteneciente a la cúrcuma, sobresale por sus beneficios a la salud contrarrestando los efectos del síndrome metabólico mediante la regulación de enzimas clave en vías bioquímicas relacionadas, tales como la glucólisis, lipólisis, lipogénesis, entre otras; así como también, con la reducción del estrés oxidativo e inflamación. En conjunto, estos beneficios a largo plazo reducen o invierten el progreso del síndrome metabólico hacia una afección más grave. Múltiples estudios, incluyendo estudios clínicos aleatorizados y otras revisiones bibliográficas, comprobaron la eficacia de la curcumina ante distintas alteraciones teniendo resultados positivos. Además, investigaciones recientes, incluyendo estudios clínicos en humanos y animales, han demostrado que la curcumina no es tóxica, ya que incluso a altas dosis no produce alteraciones significativas; por el contrario, aporta beneficios al estilo de vida humano. Si bien se necesitan más estudios para comprender mejor todos los efectos de la curcumina, aún así es prometedora como agente quimiopreventivo frente al desarrollo del síndrome metabólico y sus secuelas, con tal de integrar la curcumina y sus derivados como parte de los componentes de futuros medicamentos o tratamientos en distintas enfermedades, especialmente el síndrome metabólico
Nutrients and foods associated with people's emotional state: Scientific advances and future perspectives
No full textThis review is scientific research that seeks to explore the relationship between the consumption of certain foods and the emotional state, determining the effects that these foods produce when consumed by individuals. The intake of specific foods containing certain functional properties may help enhance our emotional health. There are particular nutrients present in certain foods that play an important role in overall health, especially in brain function. The objective of this review study was to highlight double-blind studies in humans that demonstrate the effectiveness of nutrients present in foods that interact with neurotransmitters (melatonin, endorphins, serotonin, dopamine, and oxytocin), which affect people's mood and well-being. For this study, specialized journals and scientific articles published in the last five years were selected. The results show that there is a wide variety of foods that contribute to people's well-being when consumed, and that this is not exclusive to a particular group of foods. Thus, meat products, dairy products, fruits, vegetables, and seafood, among others, contain nutrients with functional properties associated with people's emotional state. Finally, future studies should incorporate other variables such as ethnic groups, race, age, and body type, which may affect the results obtained
Phytochemical profile of native wild plants of Central Kalimantan with potential use for the development of functional foods and sustainable dietary interventions
No full textThe study investigates the phytochemical profiles of selected wild local vegetables in Central Kalimantan, Indonesia, assessing their potential health benefits in addressing nutritional deficiencies prevalent in the region. A comprehensive analysis was conducted on key metabolites, including phenols, flavonoids, carotenoids, alkaloids, phytosterol, terpenoid, saponin, and glucosinolates. The vegetables examined in this study included Solanum torvum, Cnesmone javanica, Gymnopetalum cochinense, Stenochlaena palustris, Helminthostachys zeylanica, Nauclea orientalis, Neptunia oleraceae, Crinum sp., Etlingera elatior, Calamus sp., Solanum ferox, Colocasia esculenta, Diplazium esculentum, and Rorippa indica. Using the Folin-Ciocalteu method, the total phenolic content in the ethanolic extract ranged from 107.20 to 7393.10 mg GAE 100 g-1. Total flavonoids varied from 27.17-1163.82 mg QE 100 g-1 fresh weight. Carotenoids, alkaloids, phytosterols, terpenoid, saponin ranging from 1.273-1448.80 mg 100 g-1, 78.94-1061.67 mg 100 g-1, 168.33 - 4926.67 mg 100 g-1, 914.44-15503.33 mg 100 g-1, respectively. Additionally, saponins and glucosinolates were found in concentrations ranging from 1742.22 to 19164.44 mg 100 g-1, and 92.4 to 4726.52 mg 100 g-1, respectively. N. orientalis, N. oleracea, and R. indica showed strong potential as functional foods due to their high levels of antioxidants and anti-inflammatory compounds. R. indica and D. esculentum stand out for their rich carotenoid. Additionally, the substantial amounts of phytosterols, saponins, glucosinolates, and terpenoids in N. oleracea, H. zeylanica, R. indica, and D. esculentum. Linking phytochemicals to health supports targeted diets for vulnerable groups, strengthened through diverse local vegetables and culturally adapted functional food products
Perturbation of a biological control model of malaria considering species competition
No full textThis work studies a mathematical model describing the transmission dynamics of malaria, incorporating intraspecific competition in human and mosquito populations, and biological control through larvivorous fish. We prove the existence of a compact attracting set for the proposed system of differential equations. Through stability analysis, we characterize the disease-free and endemic equilibrium points, determining epidemiologically relevant thresholds. The basic reproduction number (R0) is a key parameter: when R0 ≤ 1, the disease-free equilibrium is globally asymptotically stable, whereas for R0 > 1, a stable endemic equilibrium emerges. Numerical simulations validate the theoretical results and reveal the regulatory effect of intraspecific competition on disease prevalence. Finally, we generalize previous models by incorporating competitive interactions and vector management strategies.This work studies a mathematical model describing the transmission dynamics of malaria, incorporating intraspecific competition in human and mosquito populations, and biological control through larvivorous fish. We prove the existence of a compact attracting set for the proposed system of differential equations. Through stability analysis, we characterize the disease-free and endemic equilibrium points, determining epidemiologically relevant thresholds. The basic reproduction number (R0) is a key parameter: when R0 ≤ 1, the disease-free equilibrium is globally asymptotically stable, whereas for R0 > 1, a stable endemic equilibrium emerges. Numerical simulations validate the theoretical results and reveal the regulatory effect of intraspecific competition on disease prevalence. Finally, we generalize previous models by incorporating competitive interactions and vector management strategies
Programa de gestión pedagógica para la mejora de la convivencia escolar en una Institución Educativa
No full textEste estudio tuvo como objetivo evaluar el impacto del programa en la convivencia escolar, abordando relaciones interpersonales, disciplina, relación social, victimización y comportamientos violentos. Con un enfoque cuantitativo, de tipo experimental y diseño preexperimental, se aplicaron pretest y postest a un grupo único conformado por 51 docentes de nivel secundario de la Institución Educativa 81014 “Pedro Mercedes Ureña". Los instrumentos empleados incluyeron cuestionarios validados y guías de observación, analizados con herramientas estadísticas como SPSS y Minitab. Los resultados revelaron mejoras significativas en todas las dimensiones evaluadas, destacándose una reducción en conductas disruptivas y comportamientos violentos, fortalecimiento de la cooperación, inclusión y respeto, así como una disminución en la victimización entre iguales y hacia el profesorado. La prueba de rangos con signo de Wilcoxon arrojó un valor de significancia de 0,000, evidenciando el impacto positivo del programa. Se concluye que el programa es una herramienta eficaz para transformar la convivencia escolar, promoviendo un ambiente más armonioso e inclusivo. Este hallazgo subraya la importancia de implementar estrategias pedagógicas integrales para mejorar las dinámicas escolares y el bienestar de la comunidad educativa