Jurnal Poltekkes Kemenkes Aceh
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    EKSTRAK BIT MERAH (BETA VULGARIS L) MENINGKATKAN EKSPRESI RESEPTOR ESTROGEN-α PADA RATTUS NORVEGICUS BETINA YANG DIPAPAR ASAP ROKOK

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    ABSTRACTBackground: Cigarette smoke contains about 4000 chemical compounds that are  harmful  and  toxic  to  human  health.  Exposure  to  cigarette  smoke  causes oxidative  stress  in  the  endometrium,  thereby  inhibiting  the  proliferation  of endometrial cells  through various mechanisms  that result in disruption of  the menstrual  cycle  and  contribute  to  infertility.  Objective:  The  aim  of  the  study was  to  prove  the  effect  of  red  beetroot  extract  (Beta  vulgaris  L)  on  the expression  of  estrogen  receptor  in  female  white  rats  (Rattus  norvegicus) exposed  to  cigarette  smoke.  Methods:  The  research  method  is  True Experimental  Post  Test  Only  Control  Group  using  25  white  female  Rattus Norvegicus rats divided into 2 control groups and 3 treatment groups by giving red beet extract orally at a dose of 125 mg/KbBW/day, 250 mg/KgBW/ day, and  500  mg/KgBW/day  and  exposed  to  cigarette  smoke  as  much  as  2 sticks/day  for  8  weeks.  Then,  uterine  organ  was  taken  to  measure  the expression of estrogen receptor by immunohistochemical method. Results: This study showed that cigarette smoke exposure decreased the amount of estrogen receptor  expression  between  the  control  group  and  the  treatment  group  who were  exposed  to  cigarette  smoke  for  8  weeks  (56  days).  Conclusion:  The administration  of  red  beet  extract  at  a  dose  of  125  mg/KbBW/day,  250 mg/KgBW/day,  and  500  mg/KgBW/day  had  an  effect  on  increasing  the expression  of estrogen  receptors  in female  Rattus  Norvegicus  rats  exposed  to cigarette smoke.  ABSTRAKLatar Belakang: Asap rokok mengandung sekitar 4000 senyawa kimia yang berbahaya  bersifat  toksik  bagi  kesehatan  manusia.  Paparan  asap  rokok menyebabkan  terjadi  stres  oksidatif  di  endometrium  sehingga  menghambat proliferasi  sel  endometrium  melalui  berbagai  mekanisme  yang mengakibatkan  gangguan  siklus  menstruasi  dan  berkontribusi  terjadi infertilitas.  Tujuan:  Penelitian  bertujuan  untuk  membuktikan  pengaruh ekstrak  Bit  merah  (Beta  Vulgaris  L)  terhadap  ekspresi  reseptor  estrogen  α pada  tikus  putih  betina  (Rattus  Norvegicus)  yang  dipapar  asap  rokok. Metode:  Metode  penelitian  yaitu  True  Experimental  Post  Test  Only  Control Group  menggunakan  25  ekor  tikus  betina  putih  Rattus  Norvegicus  dibagi menjadi  2  kelompok  kontrol  dan  3  kelompok  perlakuan  dengan  pemberian ekstrak  Bit  merah  melalui  oral  dengan  dosis  125  mg/KbBB/hari,  250 mg/KgBB/hari, dan 500 mg/KgBB/hari serta dipapar asap rokok sebanyak 2  batang/hari  selama  8  minggu.  Kemudian  dilakukan  pengambilan  organ uterus  untuk  mengukur  ekpresi  reseptor  estrogen  α  dengan  metode imunohistokimia.  Hasil:  Penelitian  ini  menunjukkan  bahwa  paparan  asap rokok  mengalami  penurunan  jumlah  ekspresi  reseptor  estrogen  α  antara kelompok kontrol dan kelompok perlakuan yang dipapar asap rokok selama 8 minggu (56 hari). Kesimpulan: Pemberian ekstrak Bit merah dengan dosis 125  mg/KbBB/hari,  250  mg/KgBB/hari,  dan  500  mg/KgBB/hari berpengaruh terhadap meningkatnya ekpresi reseptor estrogen α pada tikus betina Rattus Norvegicus yang dipapar asap rokok.

    Pengaruh ekstrak daun pepaya (Carica papaya linn) terhadap larvasida Aedes aegypti

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    Background: Transmission of Dengue Hemorrhagic Fever (DHF) is strongly influenced by the presence of Aedes aegypti mosquito larvae. The most effective method for tackling DHF is by killing the presence of Aedes aegypti larvae. Reducing the negative impact of using chemical larvicides can be done through a safer alternative model, namely natural larvicides from plants. The plant studied with a characteristic ability to kill Aedes aegypti larvae is papaya leaves. Papaya leaf extract contains compounds of alkaloids, flavonoids, papain, saponins, tannins, and papain, which can kill Aedes aegypti larvae.Objective: This study aims to determine the effectiveness of papaya leaf extract (Carica papaya Linn) and the effect of concentration as Aedes aegypti larvicide.Method: The design used in this study was experimental, using 240 Aedes aegypti larvae, three treatments, and three repetitions. The research was carried out at the Laboratory of the Environmental Health Department of Aceh Health Polytechnic, Ministry of Health in 2021. The data was collected through observations every 1 hour for the first 3 hours. The analysis used was the One Way Anova statistical test and continued with the Least Significance Different (LSD) test at 95% CI.Results: The results showed that the average mortality of Aedes aegypti larvae was at a concentration of 10% (10), a concentration of 20% (13), and a concentration of 30% (16). The results of the Anova test showed that giving papaya leaf extract affected the mortality of Aedes aegypti larvae (p = 0.000). The most effective concentrations in killing Aedes aegypti larvae were 20% and 30%.Conclusion: Papaya leaf extract was very effective as a larvacide of Aedes aegypti, and it was found that concentrations of 20% and 30% were the best formulas for larvicides

    Sanitasi rumah dan stunting di Wilayah Kerja Puskesmas Labuan Kabupaten Donggala

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    Poor home sanitation can increase the risk of stunting in children. The study aims to analyze the risk factors for stunting based on house conditions, sanitation facilities, and occupant behavior. Observational research using a case-control study design was carried out in September–December 2020. The sample size was 60 toddlers (30 cases and 30 controls) taken randomly by simple arithmetic. Case samples are stunted toddlers based on e-PPGBM data. The control sample is a typical toddler who is the closest neighbor to the case with age equivalence. Respondents were mothers of toddlers. Data on the physical condition of the house and sanitation facilities were obtained through direct observation, while data on the behavior of the house occupants were obtained through interviews. Data processing was carried out by cleaning and editing, coding for categorical variables, entry and data processing. Data were analyzed using the Chi-square test and odds ratio at 95% CI. The house's physical condition (p= 0,058; OR= 8,83) and the behavior of the householder in managing sanitation are risk factors for stunting (p= 0,002; OR= 6,91). In conclusion, toddlers who live in houses with physical conditions that do not meet health requirements are at risk of experiencing stunting 8,83 times. Residents of houses whose behavior does not meet sanitation requirements risk 6,91 times experiencing stunting in toddlers

    Differences in the effect of health promotion media using booklets and audio visuals on the level of caries knowledge 6th grade student dental 09 Aie Pacah Elementary School

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    Dental and oral health problems generally occur due to low public knowledge about good oral and dental care. This study aimed to determine the effect of health promotion media using booklets and audiovisuals on the level of dental caries knowledge of 6th-grade students of SDN 09 Aie Pacah. This type of research is quantitative, using a quasi-experimental method with a two-group pretest-posttest research design. The research sample comprised 58 respondents who were divided into 2 groups, namely 29 respondents for each group, using the total sampling technique. Data analysis includes paired t-tests and independent t-tests. The results showed the difference in knowledge before and after dental caries health education in respondents with booklet media (p= 0,000) and audiovisual media (p= 0,000). There was no difference between the groups who had been given health education using booklets and audiovisual media on the dental caries knowledge of 6th graders at SDN 09 Aie Pacah (p= 0,863). In conclusion, booklets and audiovisual media increase knowledge about dental caries health in elementary school children. There is no difference in dental health education using the booklet and audiovisual media

    Potret pengetahuan bidan Puskesmas/Desa dalam mendeteksi status gizi buruk pasca sosialisasi GEMPITA ASA di Provinsi Aceh

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    Background: Midwives are the health professionals responsible for educating the public and recognizing nutritional issues in infants. The use of the MUAC scale is a straightforward and highly sensitive approach for detecting nutritional problems in toddlers. The use of the MUAC scale for toddlers is anticipated to provide an independent technique for detecting nutritional abnormalities in toddlers, particularly malnutrition.Objective: To describe the knowledge of midwives in Aceh Province on the detection of severely underweight and underweight using anthropometric indicators and the usage of the MUAC scale for toddlers.Method: This research is a cross-sectional examination of a program's effectiveness. This study's sample consisted of 553 community health center/village midwives from the Aceh province. The knowledge of midwives was assessed via a questionnaire administered following the "National Nutrition Day Webinar: Preventing child mortality through early detection of nutritional issues" presentation. Data processing begins with the processes of editing, coding, and cleansing. The analysis of data was performed univariately.Results: Results indicated that the community health center/village midwives' ability to diagnose growth abnormalities in children under the age of five fell into three categories: moderate (68.0%), good (14.1%), and very good (17.9%). In addition, more than 50% of community health center/village midwives are aware of the function of the MUAC scale (severely underweight if the MUAC < 11.5 cm), but more than 50% are unaware of the criterion for malnourished children (if they meet one of the criteria). Indicators, specifically WHZ index < -3 SD; MUAC < 11.5 cm, and the presence of edema.Conclusion: The midwives are more adept at identifying malnutrition and undernutrition in children under five than anthropometrists are at doing so

    Dampak konsumsi pangan tinggi kandungan indeks glikemik dengan kejadian diabetes mellitus tipe-II di Kabupaten Pidie

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    Background: Type II diabetes mellitus is a disorder of glucose metabolism disease in which the body fails to control the glucose that enters food, so blood sugar levels become high. One of the factors causing type II diabetes mellitus is the habit of consuming foods with a high glycemic index.Objective: This study aims to determine the relationship between high glycemic index food consumption and the incidence of type II diabetes mellitus.Method: The cross-sectional research design was carried out in Pidie Regency in 2021. A sample of 50 aged 30-65 years was taken purposively. Data collection of high glycemic index food consumption using a questionnaire and type-II diabetes mellitus based on examination of blood sugar levels. Statistical analysis used the Chi-square test at 95% CI.Results: The study's results have found that people with diabetes mellitus very often consume foods containing a high glycemic index, which is 40.0%. There was a significant effect between the consumption of high glycemic index food and the incidence of type II diabetes mellitus (p= 0.003).Conclusion: Consumption of food with a high glycemic index significantly impacts the incidence of type-II diabetes mellitus in the 30-59 year age group. Keywords

    EFEKTIVITAS AROMATERAPI LAVENDER (LAVANDULA ANGUSTIFOLIA) DAN PEPPERMINT (MENTHA PIPERITA L) TERHADAP INTENSITAS MUAL DAN MUNTAH PADA IBU HAMIL TRIMESTER I

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    ABSTRACTBackground: Nausea Vomiting usually occurs in the morning. Nausea and vomiting occur in Primigravida between 60-80% and in multigravida between 40-60%. Treatment for nausea and vomiting is non-pharmacological therapy. One of the non-pharmacological therapies that can be given to treat nausea and vomiting is aromatherapy. Objective: This study aims to analyze the comparison of the effectiveness of Lavender and peppermint aromatherapy on the intensity of nausea and vomiting in pregnant women in the first trimester Methods: This study is a quasi-experimental study with a non-equivalent control group design. The research sample was 30 people at Langsa Barat Public Health Center Langsa City. The samples were divided into 2 treatment groups, namely the lavender aromatherapy group and the peppermint aromatherapy group. Data were analyzed by analyzing paired t-tests and Independent T-Test. Result: showed that the lavender aromatherapy group was effective against the intensity of nausea and vomiting in pregnant women with a sig value. 0,000 and the peppermint group was effective against the intensity of nausea and vomiting in pregnant women with sig. 0,000. In testing with the Independent T-Test, the mean results of the lavender group were 5.80 and the mean peppermint was 6.60 with a sig. 0.283 Conclusion: Peppermint aromatherapy is more effective in reducing the intensity of nausea and vomiting in pregnant women. ABSTRAKLatar Belakang : Mual Muntah biasa terjadi pada pagi hari. Mual muntah terjadi pada Primigravida bekisar antara 60-80% dan pada multigravida bekisar 40-60%. Pelatalaksanaan yang dapat dilakukan pada mual muntah adalah dengan terapi nonfarmakologi. Salah satu terapi nonfarmakologi yang dapat diberikan untuk penanganan mual muntah yaitu aromaterapi. Tujuan: untuk menganalisis perbandingan efektifitas aromaterapi Lavender Dan peppermint terhadap intensitas mual dan muntah pada ibu hamil trimester I. Metode : Penelitian quasi eksperiment dengan rancangan penelitian non equavalen control group design. Sampel penelitiansebanyak 30 orang di Puskesmas Langsa Barat Kota Langsa. Sampel dibagi menjadi 2 kelompok perlakuan yaitu kelompok aromaterapi lavender dan kelompok aromaterapi pappermint. Data dianalisis dengan melakukan uji analisis paired t-test dan Independent T Test. Hasil Penelitian : menunjukkan pada kelompok aromaterapi lavender efektif terhadap intensitas mual muntah pada ibu hamil dengan nilai sig. 0,000 dan kelompok peppermint efektif terhadap intensitas mual muntah pada ibuhamil dengan niali sig. 0,000. Pada pengujian dengan Uji Independent TTest didapatkan hasil mean kelompok lavender sebesar 5.80 dan mean peppermint sebesar 6.60 dengan nilai sig. 0.283. Kesimpulan : aromaterapi peppermint lebih efektif dalam menurunkan intensitas mualmuntah pada ibu hamil

    Skrining parasit malaria pada kantong darah di Unit Transfusi Darah Palang Merah Indonesia (PMI) Cabang Kota Banda Aceh

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    Background: Blood screening of donors has been routinely conducted to anticipate various infectious diseases transmitted through blood transfusion. However, screening for malaria has not been a top priority at the Blood Transfusion Unit (BTU), despite Banda Aceh City being a malaria-endemic area. Screening for malaria is essential to reduce transmission risk and ensure recipient transfusion safety.Objectives: The study aimed to determine the results of the Rapid Diagnostic Test (RDT) examination of malaria in blood bags at the BTU in the Indonesian Red Cross (IRC)  branch in Banda Aceh.Methods: The study used an experimental design with the RDT method, which was conducted at the IRC Banda Aceh in December 2021. This study uses a descriptive research design through a cross-sectional approach. The total sample in this study was 30 donor blood bags taken by simple random sampling.Results: The results showed that malaria was found positive in 1 donor blood sample (3.33%) and 29 (96.67%) negative for malaria.Conclusion: The frequency of malaria screening results is predominantly negative. However, there are some positive ones in donor blood at the Banda Aceh branch of the Indonesian Red Cross Blood Transfusion Unit

    Sensitivitas dan spesifisitas kartu menuju sehat model tikar monitoring pertumbuhan dalam mendeteksi stunting pada balita

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    One of the obstacles faced in determining the diagnosis of stunting is the complexity and lack of accuracy of health workers, especially Integrated Healthcare Center (called Posyandu) cadres, in using current equipment (microtoice) and the lack of accuracy of nutrition workers in interpreting nutritional status.  The purpose of the study was to measure the validity of the KMS Tikar through sensitivity and specificity testing in detecting stunting in toddlers. The study used a Research & Development design, with the gold standard using a body length board and Z-Score calculation from 2005 WHO reference standard, carried out in 30 clusters in Darul Imarah District, Aceh Besar, from April to October 2019, and a sample of all children aged 0-24 months which is as many as 204 children. Data was collected through anthropometric measurements such as length and age and z-score data on the HAZ index. The WHO Anthro processed the data. The analysis was carried out with the Se and Sp tests. The results showed that children's body length measurement with both tools (Gold standard and growth chart is a mat model) had 0,073 cm. At the same time, the proportion of nutritional status in the stunting category was more commonly found in measurements using growth charts of mats (23,5%) compared to Gold Standards (12, 3%). The validity test results obtained a very high sensitivity value (100%) with a specificity of—87,15%. While the positive predictive value is 52,08%, and the negative predictive value is 100%. In conclusion, the growth monitoring mat growth chart has high sensitivity and specificity value and is very good for use as a tool to detect stunting in children aged 0-24 months

    Keterkaitan pola pangan harapan (PPH) dengan kejadian stunting pada balita

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    Background: Food security from the consumption pillar is reflected by the loyal ability of citizens to consume food that is sufficient in quantity and nutritional quality, safe, diverse and affordable. Consumption of adequate and nutritionally balanced food is a form that must be met to minimize nutritional problems including stunting.Objectives: This study aims to determine the relationship between the Expected Food Pattern (PPH) and the incidence of stunting in toddlers.Methods: The type of research used is observational research, using a cross sectional design. The research sample is 90 samples. The research location is in North Kluet District, Aceh Regency. Data analysis using SPSS Software Independent Test t-test. Research data will be presented in the form of univariate and bivariate analysis.Results: The results showed that there was no difference in the Expected Food Pattern (PPH) score between stunting toddlers and the PPH score for normal toddlers, the p value = 0.553 (p > 0.553).Conclusion: In conclusion, the PPH score in stunting toddlers with normal toddlers does not show a difference on average in North Kluet District, South Aceh

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    Jurnal Poltekkes Kemenkes Aceh
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