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The acute effect of the antioxidant drug “U-74389G†on mean corpuscular volume levels during hypoxia reoxygenation injury in rats
Full text linkBackground: This experimental study examined the effect of the antioxidant drug “U-74389Gâ€, on a rat model and particularly in a hypoxia – reoxygenation (HR) protocol. The effects of that molecule were studied hematologically using mean blood corpuscular volume (MCV) levels.Methods: 40 rats of mean weight 231.875 g were used in the study. MCV levels were measured at 60 min of reoxygenation (groups A and C) and at 120 min of reoxygenation (groups B and D) with administration of the drug U-74389G in groups C and D.Results: U-74389G administration significantly increased the predicted MCV levels by 2.88%+0.69 (p= 0.0002). Reoxygenation time non-significantly increased the MCV levels by 0.57%+0.83% (p=0.4103). However, U-74389G administration and reoxygenation time together significantly increased the MCV levels by 1.60%+0.43% (p= 0.0005).Conclusions: U-74389G administration whether it interacted or not with reoxygenation time has significant increasing short – term effect on recovery pathophysiology of MCV values
Design and Development of Reconstitutable Sustained Release Suspension of Linezolid by Spray Drying Technique
Full text linkThe purpose of this research work was to design and evaluation of a stable reconstitutable Sustained release suspension for pediatric and geriatric patients using spray drying techniques. Linezolid is the drug of choice in treatment of infections caused by multi-resistant bacteria. The microcapsules were prepared by spray drying method. Drug loaded microcapsule were prepared using Eudragit RS and RL100 and ethyl cellulose in three different polymer ratio. The influence of the drug to polymer ratio and feed flow rate was studied on the properties of microcapsule using a 32factorial design. The drug to polymer ratio (X1) and feed flow rate (X2) were selected as independent variable and percentage yield, particle size, encapsulation efficiency, Q6, Q8, t90% were selected as dependent variables. Regression analysis and ANOVA were performed for dependent variables. Dissolution data were fitted to various kinetic models on drug release of microcapsule. The prepared SR suspensions were evaluated for flow properties, determination of rheological and sedimentation behavior. From the factorial batches, optimize batch of microcapsules were used for preparation of reconstitutable SR suspension using various suitable suspending agents. Accelerator stability study of reconstitutable SR suspension was performed as per ICH guideline
Bionematicidal Potentials of Azadirachta indica (A. juss), Vernonia amygdalina (DEL), Manihot esculenta, Carica papaya. L. and Citrus sinensis on Meloidogyne incognita of Capsicum annuum, Var. Bell
Full text linkPlant parasitic nematodes especially Meloidogyne species are linked to global reduction or loss in the yield of agricultural produce. If plant diseases are left unchecked, it could lead to food shortage. Synthetic nematicide could induce toxicity, environmental degradation and are expensive. Root-knot nematodes (RKN) are devastating as it affects many economically important agricultural crops globally. The bionematicidal potential of pepper plant nematode was investigated with five plants (Azadirachta indica, Vernonia amygdalina, Manihot esculenta, Carica papaya. and Citrus sinensis) in a two-phased trial, at concentrations of 20, 30 and 40g within exposure periods of 30, 60 and 90-days. Generally, Compared to the control, all bionematicides similarly showed significant nematotoxocity for both trials with significant difference (p < 0.05). Thus the degrees of nematotoxicity is reported as: A. indica > V. amygdalina > C. sinensis > C. papaya > M. esculentus. Based on the findings of this research, we therefore conclude that the tested plant demonstrated significant levels of nematotoxicity and can be so regarded as Bionematicides
Conservation of angular momentum and virial theorem in variable mass dynamics
Full text linkWhittaker’s mass variation law in variable mass dynamics is applied to many body problem of celestial mechanics with a view to re-establishing thereof some important theorems. It is proved that the conservation of angular momentum still holds irrespective of the manner of mass variation. The virial theorem, in several forms, with the same mass variation principle as Whittaker’s has been proposed and proved. Needless to mention that classical Celestial Mechanics is based on a single physical law viz universal law of gravitation which in the present subject is coupled with a relevant mass-variation law, Sundman’s inequality and the law of energy are modified in the light of mass-variation principle in case of a system of n bodies, for which the sum of kinetic and potential energies represents an integral equation with time as an independent variable. A sharp form of virial theorem and hence growth of the system with variable masses are studied and analyzed in comparison with fixed mass criteria [1]. Mathematical analysis including L’Hospital’s rule and convolution theorem of integral equation are applied to evaluate some limiting functions involving the moment of inertia, total mass and time and also to set forth some inequality identities involving the initial total mass and the distance of maximum and minimum spacing between the particles (celestial bodies)
Intestinal parasites and haemoglobin concentrations in pregnant women attending Braithwaite Memorial Specialist Hospital, Port Harcourt
Full text linkThis study was carried out between January to June, 2014 at Braithwaite Memorial Specialist Hospital, Port Harcourt to determine the haemoglobin level and intestinal parasites in pregnant women attending antenatal clinic of the hospital. In total, 200 stool and blood samples were collected from the women. The stool samples were examined using direct wet preparation and formol ether concentration technique while the haemoglobin levels of the women were estimated using cyanmethaeoglobin technique. The overall prevalence of E. histolytical, A. Lumbricoides, Hookworm Spp, and T. trichuria was 8(4.00), 58(29.00), 8(4.00) and 8(4.00) respectively. The proportion of pregnant women with helminithic infestation was 60 (30.0%) while their mean Heamoglobin concentration was 10.85+0.32g/dl while the pregnant women without helminthic infestation (140(70.0%) had Heamoglobin concentration of 11.03+0.16g/dl (P<0.05). The study has shown that pregnant women with intestinal parasites had low haemoglobin level. This may be attributed to poor socioeconomic status of the women coupled with poor environmental sanitation and lack of clean portable water supply may have contributed to the high prevalence
The effect of using renewable energy In Public Health
No full textThe human societies go towards industrialization; the incidence of infectious diseases is reduced. On the other hand, the rate of non-communicable diseases such as cancer, heart disease, vascular and infectious diseases is growing up. The use of fossil fuel pollutants of the most important causes of these diseases. Renewable energy is the most important feature of health promotion. Use of renewable sources is clean energy and environmental protection. The major consequence of the continued use of fossil fuels, disease and environmental problems. In this study, the disadvantages of fossil fuels, alternative and renewable energy as a solution for reducing air pollution and improving public health will be presented
Plastral shape isometry in Western Hermann's tortoise (Testudo hermanni hermanni)
No full textElliptical Fourier Analysis is a good technique for characterizing the shape of complex biological and non-biological morphologies. The current investigation aimed to study plastral pigmentation contour (black areas of the ventral shell) changes, according to body size (plastral length), in Western Hermann's tortoise (Testudo hermanni hermanni), using Elliptical Fourier Analysis. For this goal, 52 domestic pure tortoises from authorized private breeders were selected, ventral pictures were individually taken and their contour automatically digitized and straight-line plastron length obtained. Straight-line plastron length ranged from 83.6 to 150.6 mm (for males) and from 78.9 to 171.8 mm (for females).. A regression was performed for second and third harmonics as dependent variables, against plastral length (log transformed) as independent variable. Based on this sample, it is demonstrated that plastral pigmentation design does not change along animals’ life-history. Therefore, a plastral pigmentation shape isometry can be supposed, at least for this subspecies
The twisted gut: Role of primary anastomosis without colonic lavage
Full text linkBackground : The twisted gut or the sigmoid volvulus has a multitude of treatment options ranging from colonic decompression to staged procedures such as primary resection anastomosis with covering colostomy followed by colostomy closure at a later date.Objective : This study aims to evaluate the efficacy and safety of primary resection and anastomosis followed by anal dilatation without on table colonic irrigation or diversion colostomy in cases of acute sigmoid volvulus.Methods : This study was carried out over a span of three years and seven months at a teaching hospital in West Bengal. One hundred consecutive cases of acute sigmoid volvulus who underwent primary resection and anastomosis without diversion colostomy were included in the study.Results : There were 94 males and 6 females. The age ranged from 35 to 72 years, the majority ( 65 % ) of the patients being in the age group of 41-60 years. All the patients underwent primary resection and anastomosis without on table colonic irrigation. Superficial wound infection was detected in 18% patients.. There was no clinical anastomotic leak, intra abdominal abscess or recurrence of volvulus or mortality in our series.Conclusion : In conclusion, primary resection and anastomosis of the colon without faecal diversion for acute sigmoid volvulus is safe and can be accomplished without any mechanical bowel preparation or on table colonic irrigation
Degradation of spent tea waste by vermicomposting and its effect on growth of Abelmoschus esculentus
Full text linkVermicompost is the stable, organic matter that remains after the earthworms feed on the waste materials that occurs due to its decomposition in the gut of the earthworm under controlled conditions. Compost is a rich source of vitamins, hormones, enzymes, macro and micro nutrients which when applied to plants help in efficient growth. Vermicompost was sought to be made by putting spent tea waste as the worm feed. The present study has been carried out to analyze enzymes, physicochemical characteristics, and micro and macro nutrients present in the compost at regular interval of time and also a comparative study was done on the effect of compost on growth parameters namely germination percentage, root length, shoot length and number of leaf count in Abelmoschus esculentus after 30th day of planting. The results of the study revealed that the enzyme activities (amylase, cellulase, protease and invertase) and total macronutrients (N, P, K) and micronutrients (Mn and Cu) showed elevated levels in compost than control. The compost applied plant (Abelmoschus esculentus) showed increased germination percentage, root length, shoot length and number of leaves than the compost untreated plant
Symplectic structures on coadjoint orbits of Lie groups
Full text linkThis article is devoted to the explicit determination of symplecticstructures on coadjoint orbits of Lie groups. It will rst be devoted tothe study of adjoint and coadjoint orbits of a Lie group with an applicationin the case of special orthogonal group SO(n). We will see how to determineexplicitly a symplectic structure on the orbit of the coadjoint representationof a Lie group. Particular attention is given to the groups SO(3) and SO(4).Mathematics Subject Classication (2010). 53D30, 70G65