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    Psychological Care for Childhood Cancer Patients

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    Charlotte, age seven, is playing with the toys at the doctor’s office. Meanwhile, her parents’ minds have gone blank, and their ears are ringing with the news. Faces drained of color and painted with looks of pain and fear, they stare forward in a hypnotic state as the physician declares the diagnosis. Charlotte has cancer. The disease is not sparing of even the youngest in our world, cruel as it may seem to some. However, cancer does not discriminate between the children and the elderly, or anyone in between. Now, what does this mean for Charlotte and her parents? There are several aspects of care which must be planned out, inclusive of physical, mental, emotional and spiritual needs. Psychological care of cancer patients is one of the vital components in a plan of care. Psychological care involves treating the mind, as opposed to physical care which treats ailments within the body. Psychological treatment works to amend deficits in emotional, behavioral, or mental functioning (Psychological treatments, 2019). This form of care focuses on reducing the patient’s symptoms, furthering the understanding of their mental illness, comprehending problems in their thought processing and working to resolve them, altering their current maladaptive behaviors, and improving their quality of life (Psychological treatments, 2019). Such care can be provided in an individualized setting, a group setting, and even online. There are subcategories of treatment that cater to an individual’s needs depending on what they are grappling with, cognitively and behaviorally

    Three Gastrointestinal Assays

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    Gastrointestinal (GI) functionality relies on the spontaneous, rhythmic and coordinated propagation of muscular contractions in the GI tract, or GI motility. Without these coordinated motor patterns, digestion falters, and results in problems with digestion. Disrupted or un-coordinated motor patterns are associated with altered GI transit times. GI transit is the amount of time necessary for intestinal contents to move through the GI tract. GI transit is measured in patients complaining about abdominal discomfort to determine if discomfort results from a true dysmotility or from idiopathic symptoms. GI transit assays help to determine appropriate treatments but idiopathic symptoms, or pain from an unknown cause, is very common. The zebrafish is an attractive model system for human GI motility because the entire GI tract can be observed in intact zebrafish larva. In current methods, larvae are fed food with a marker substance and movement through the intestine is viewed using a microscope and recorded using a digital camera. However, GI transit time is highly variable. It is possible that this variability is completely normal and results from variable GI physiology. Alternatively, it is possible that the variability is due to the assay. Three distinct GI transit assays have been published. The overall objective for this work is to determine the reliability for each assay and to better understand which assay is most appropriate for future work. The assays will be described and compared, and results comparing the assays will be presented

    An Investigation into the Role of Arf6 in MCH-mediated Rearrangements in 3T3-L1 Preadipocytes

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    Obesity has become a pandemic in our society. One potential method to alleviate this crisis is the use of pharmaceutical therapy to manage how our bodies metabolize the energy that we consume. Chronic overconsumption can lead to the activation of inflammatory responses and metabolic dysregulation, such as insulin resistance, and promote the obese condition. The pathways involved in the motility of pre-adipocyte cells are important in understanding how our bodies interpret and react to specific biochemical signals. This research is focused on a pathway that activates the expansion and migration of pre-adipocytes. Melanin-concentrating Hormone (MCH) is a neuropeptide that is known for regulating appetite and metabolism within adipocytes through the G protein-coupled receptor, MCHR1. MCHR1 is known to act through a Gq/PLC pathway to destabilize actin. Our proposed pathway is that MCHR1 activates ARNO, a guanine nucleotide exchange factor that is required in the subsequent activation of ADP-ribosylation factor 6 (Arf6). These events in succession may result in destabilized actin in murine 3T3-L1 pre-adipocytes. A pharmaceutical inhibitor of Arf6, NAV-2729, as well as the overexpression of dominant negative ARNO/Arf6 plasmids were used to determine if Arf6 was indeed a downstream signaling component in this pathway. Fluorescence microscopy was used to visualize the actin stress fibers and morphology of the cell and a scratch wound was performed to determine if the migration rate was affected. Preliminary results from our fluorescence stain show that the structure of actin was affected by NAV-2729 after MCH addition, however, additional trials and analysis are required

    Dance Artists’ and Choreographers’ Financial Sustainability in New York City Under the CreateNYC Cultural Plan

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    New York City is brimming with a plethora of diverse art, performances, exhibits, and communities, sparking many people to regard it as the Cultural Capital of the World. The New York City Department of Cultural Affairs (DCLA) has been a longtime supporter of the arts in New York City. In 2017, the DCLA released the CreateNYC Cultural Plan, which was intended to increase equity and sustainability in the art and culture sector of New York City

    Learning from Our Students: Qualitative Analysis of Feedback Forms

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    Assessment an important aspect of library instruction. This past year, we instituted a common assessment form across all of our library instruction sessions. In order to understand the responses to one of our questions, “Name three things you learned today,” we decided to employ qualitative data analysis methods (Miles et al., 2014). This presentation will discuss the instrument we used, our analysis method, and lessons learned as a result of our analysis

    Designing the Artists\u27 Book: How Graphic Design Impacts the Photographic Portfolio

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    Modifications to Undergraduate Major in Biology Adolescence (7-12) Education with Grades 5 and 6 Extension

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    The purpose of this proposal is to align the curriculum that was previously approved by the College Senate with the curriculum recently approved by SED

    Designation of CSC 434 and CSC 435 as Project Courses for the Advanced Computing Track of the Computing Science Major

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    The Advanced Computing track of the Computing Science major requires students to take a project course from a designated menu of upper level CSC courses. This proposal will expand the menu of options by adding the existing course CSC 434 and the new course CSC 435 to the existing menu, which currently includes only CSC 423 and CSC 42

    Undergraduate Social Work Program Curriculum Revision

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    The Department of Social Work, Undergraduate Program is proposing multiple course name changes and description revisions, the addition of two new courses to the plan of study (SWO2XX and SWO3XX), the removal of three courses from the plan of study (SWO302, SWO322, and SWO411), and eliminating one pre-requisite course and teaching the course as part of the required plan of study (SWO210)

    Lake Ontario Alewife, Alosa pseudoharengus, maturation and reproduction dynamics

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    Since their introduction in Lake Ontario, alewife (Alosa pseudoharengus) have dominated the forage fish community, making them the primary food source for the lake’s economically valuable sport fish populations. Therefore, alewife population dynamics can impact fishery success and management. Recently observed declines in alewife abundance and year class strength variability further increase the need to better understand alewife reproduction. The objectives of this study were to quantify maturation and reproductive dynamics of Lake Ontario alewife by 1) determining if alewife display determinate or indeterminate fecundity, 2) determining if age 2 alewife could be considered part of the spawning stock, and 3) assessing reproductive potential across alewife ages 2 to 6. We collected alewife from various locations in Lake Ontario from October 2017 to October 2018 and measured gonadosomatic index, condition factor, gonad development, spawning potential, batch fecundity, and embryo survival data. Evidence of a prolonged spawning season and the presence of multiple batches of advanced oocytes in the ovaries of alewife suggest this species display indeterminate fecundity (i.e., can spawn multiple batches of eggs in a single spawning season). Spawning potential (observed spawning and or the presence of mature gonads) was observed in 63.9% of age 2 females and 90.4% of age 2 males captured in June and July, indicating age 2 alewife should be considered part of the spawning stock. This was confirmed by the successful survival of embryos of age 2 parents. When comparing embryo survival data among all ages, older females displayed higher embryo survival, and our beta regression model suggested female age best explained observed. In addition, alewife older than age 2 appeared to have a higher proportion of indeterminate spawners, further suggesting older alewife have increased reproductive output vs younger fish. However, the lack of variation in relative batch fecundity among ages suggest other variables, such as size may better explain this variability

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