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Justapapillar Duodenal Gastrointestinal Stromal Tumor (gist) Local Resection: A Case Report
Introduction: Gastrointestinal stromal tumors (GISTs) are the most frequent non-epithelial tumors of the gastrointestinal tract (GIT). The most common location is the stomach, followed by small intestine, being very rare the cases of duodenal origin, where it can cause digestive bleeding and anemia. The surgical resection of the tumor is the gold-standard treatment and the definitive diagnosis is based on immunohistochemical analysis of the surgical specimen.Case presentation: A case of exophytic and endophytic GIST located in the second portion of the duodenum, one centimeter below the duodenal papilla, was reported in a 33-year-old female patient.Conclusion: The gold-standard treatment is surgical resection of the tumor with negative margins (R0), with no need for lymphadenectomy. Local lesion resection or duodenopancreatectomy can be performed. Duodenopancreatectomy, unlike local resection of the lesion, is associated with increased length of hospital stay and longer intraoperative time. Therefore, it should be reserved for lesions that cannot be resected locally. Fortunately, a local resection was performed, which have a more favorable prognosis
Biosynthesis, Characterization and Antimicrobial Activity of Silver Nanoparticles Using Cell Free Lysate of Bacillus Subtilis: A Biotechnology Approach
Present study was aimed at the bio-synthesis and characterization of silver nanoparticles (AgNPs) using bacterial cell free lysate of Bacillus specie isolated from iron-rust contaminated soil sample from the Niger Delta region of Nigeria. This method was cost effective, eco-friendly and an alternative to chemical synthesis which is hazardous and requiring tedious synthetic manipulation. This study also evaluated the antimicrobial effect of the synthesized silver nanoparticles. Silver nanoparticles produced by reacting cell-free lysate of Bacillus subtilis and 1 mM of aqueous silver nitrate solution were characterized by Ultraviolet-visible spectroscopy, Transmission electron microscopy (TEM) and Photon correlation microscopy (Zeta sizer). The UV-Visible spectrophotometric result revealed an absorption maxima corresponding to peaks near 428 nm, depicting reduction of ionic silver (Ag+) to silver atom (Ag0). It has already been reported that nitrate reductase enzymes are implicated in metal ion reduction reactions. The Transmission electron microscopy analysis revealed that the AgNPs size ranged between 58.24 ± 1.04 nm and 72.20 ± 2.10 nm complementing the result obtained from Photon correlation microscopy (76.86 ± 1.14 nm). The antibacterial activity of AgNPs gave highest inhibition zone diameter of 26 mm on Pseudomonas aeruginosa at the dose of 0.10 mg/ml and 14 mm on tested Candida albicans. The synthesized silver nanoparticles were found to produce a dose dependent antimicrobial inhibitory effect while surface adsorption and lysis were implicated as the mode of action
Molecular characterization of Yeasts and Bacteria isolated from Handia, an Indian traditional rice fermented alcoholic beverage.
Handia is an Indian traditional fermented alcoholic beverage prepared from rice (Oryza sativa L.) To date, no information is available about the microorganisms associated with Handia fermentation. In this study a total of twelve yeast strains isolated from Handia were identified by partial sequencing of the D1/D2 variable domain of 26S of rRNA gene. The isolates were identified and designated as Saccharomyces cerevisiae KpY, S. cerevisiae 18VSL, S. cerevisiae H15, S. cerevisiae H17, Hanseniaspora guilliermondii G1, H. guilliermondii G4, Pichia kudriavzevii H21L, Candida glabrata H3, C. glabrata H8, C. glabrata H11, C. glabrata H12 and C. tropicalis 18VLL. Sequence analysis of 26S rRNA genes revealed 100% identity with the corresponding sequences in the GenBank with the exception of P. kudriavzevii H21L which showed 99% identity. The bacterial strains BA, B16 and B4 were identified as Brevibacillus agri, Leuconostoc mesenteroides and Kocuria sp., respectively by 16S rRNA gene sequence analysis. The identification of yeast strains (KpY, 18VSL, H15, H17, G4 and H21L) was further confirmed by 5.8S-ITS-RFLP analysis. M13 PCR-fingerprinting indicated the presence of four different strains of S. cerevisiae in Handia. The result suggests that Handia constitutes a complex microbial consortium comprising a wide diversity of bacterial and yeast strains
Gamma Radiation Assisted Grafting of Low Surface Energy Long Chain Molecule on Various Types of Polyolefin Elastomers (POE)
Surface modification of polymers can lead to changes of properties such as surface wettability, adhesion, bioactivity and biocompatibility. Here, a long chain, low surface energy monomer, docecyl methacrylate (DMA), which is difficult to graft by chemical mean was grafted onto three different types of ‘Engages’ (a polyolefin elastomer, POE) in ethanol/water medium by gamma radiation. Total dose and DMA concentration were optimized for the desired amount of low degree grafting (less than 15wt%). The surface wetting properties towards water were decreased for all Engage surfaces after grafting. Mechanical properties of the base polymers remained almost unchanged after grafting
Progress in Decay of utility Intake, Process Time Assimilation and CO2 Emission in Textiles through New Generation Colorants
Textile dyeing effluents containing recalcitrant dyes are polluting waters due to their color and by the formation of toxic or carcinogenic intermediates such as aromatic amines from azo dyes. Since conventional treatment systems based on chemical or physical methods are quite expensive and consume high amounts of chemicals and energy, alternative technologies for this purpose have recently been studied. A number of new generation dyestuffs have been developed at laboratory scale to replace conventional dyestuff. Additionally, new generation dyestuffs shows very promising results for reduction of utilities and chemical consumption. In this contribution, we made a novel approach to detailed onsite investigation on water, steam, electricity and chemical minimization employing high exhaustion-fixation dyestuffs and analysis on production processes performed according to UNFCC clean Development Mechanism (CDM) promotion. Specific consumptions in wet processes were calculated by mass balance analyses. The multi-criteria decision-making methods were employed to determine suitable best available techniques
Analysis of Lean Manufacturing: A Cost Saving Approach in Garments Production Unit
Sewing process is one of the most important stages in labor intensive ready-made clothing enterprises. Quality faults occurring during this process adversely affect the product quality and product efficiency, and also increase the production cost. The aim of this study is to investigate whether the knitwear production process is under control in a knitwear production enterprise and to detect the processes with highest rates of sewing faults in sewing department and finally to make suggestions for improving the quality control. Among the Statistical Process Control methods; control list, product control chart were used in the study. “Product control chart” was used to test whether the production process is controlled in the enterprise. Furthermore, the statistical methods were employed to determine the issues that need to be done in the improvement efforts and to detect the relations between the process groups supposedly effective on faults occurring in knitwear production and the amount of faults. Also, the processes with highest amounts of sewing faults and the effects of these processes on fault rates were investigated. As a result, it was concluded that the production process was statistically not under control in the ready-made clothing enterprise. In addition, this study demonstrated that the investigation of each process group by drawing their product control charts would make significant contributions to foresee the results and prepare more effective the improvement plans.
Amalgamation of Nanodiamond and Epoxy
Nanoscale diamond particles are known as nanodiamond (ND). Nanodiamond has attracted much attention of the polymeric composite community. Owing to its superior properties, ND holds great potential to improve tribological characteristics of the composites. In epoxy/nanodiamond nanocomposite, large surface to volume ratio of ND results in dramatic increase in volume of inter-phase, i.e. polymer volume which is close enough to nanodiamond. This, in turn, allows nanodiamond to exert significant impact on epoxy properties even at low concentrations. It is critically important to have physical/covalent bond at epoxy/ND interface from nanoparticle surface to the macromolecules of the matrix. Mechanical properties, thermal properties, and electrical conductivity of the covalently compatiblized epoxy/ND composite have been found better than neat epoxy matrices and compatible composites. Epoxy/ND composite has huge range of technical applications ranging from biomedical—to—electronics—to—aerospace
The Role of Free Fibula Flap in the Reconstruction of a Mandibular Ameloblastoma: A Case Report
Introduction: The ameloblastoma is a rare odontogenic tumor of the oral cavity. It affects more the mandible than the maxilla, and has a predilection for the posterior region. Although this tumor is benign, its behavior is locally aggressive and requires the most often surgical resection margin. Case Report: A young woman aged 28, has consulted the Oral Surgery Department of Rabat, complaining of a right mandibular swelling, extended from the 46 to the right mandibular ramus, lasting for eight months. The intraoral examination revealed a swelling covered of a mucosa of normal appearance. Panoramic radiograph revealed the presence of a multi-geodic lesion at the right hemi-mandible. A biopsy was performed at the level of the lesion and concluded an ameloblastoma. The patient was subsequently referred to the Maxillofacial Surgery Service of the Hospital of Specialties of Rabat. Two teams, one of maxillofacial surgery and another one for vascular surgery, collaborated to perform a hemi-mandibulectomy with a free fibula flap graft.Conclusion : The free fibula osteocutaneous flap is the most versatile and reliable option for microsurgical reconstruction of large mandibular defects
Advanced Oral Squamous Cell Carcinoma: A Case Report
Introduction- Oral cancer is the sixth most common cancer globally with a wide geographic variation. In India, there is a trend towards increasing incidence and delayed presentation of oral cancer as approximately 50% patients present at stage III or IV where the lower socioeconomic strata of society play a vital role.Presentation of Case A 35 years’ male reported with the complaint of rapidly increasing ulcer in mandible. Extraoral examination revealed presence of hard nodular swelling with orocutaneous perforation while on Intraoral examination an ulcero-infiltrative, indurated lesion was present. The diagnosis was confirmed by histopathopathological examination after radiographic evaluation.Conclusion- Despite an improvement in diagnostic and management techniques, the age-standardized mortality rates in oral cancer are constant. This article describes a case of advanced oral squamous cell carcinoma occurring at early age with an emphasis on clinical aspects of squamous cell carcinoma