Ivy Union Publishing (E-Journals)
Not a member yet
411 research outputs found
Sort by
Burkitt's Lymphoma as Primary Adrenal Lymphoma Diagnosed on Fine Needle Aspiration Cytology : A Rare Case Report
Get PDFIntroduction :Primary adrenal lymphoma presenting as Burkitt’s lymphoma is an extremely rare entity. Although biopsy or excision is often needed for definitive diagnosis computed tomography guided fine needle aspiration has great diagnostic value in detection of primary adrenal lymphoma.Presentation of case : A case of a 20 yr old male with a right adrenal mass diagnosed as Burkitts lymphoma on Fine Needle Aspiration Cytology (confirmed by bone marrow and cytogenetics) has been reported.Conclusion : Fine Needle Aspiration Cytology as an initial investigation tool can be very effective for detection of unusual presentation like an adrenal mass in a case of Burkitt's lymphom
Dynamic Mechanical Behavior & Analysis of the Jute-Glass Fiber Reinforced Polyester Hybrid Composites
Get PDFThe development of composite materials based on the reinforcement of two or more fiber types in a matrix leads to the production of hybrid composites. In the present work, hessian jute cloth, non-woven E-glass and polyester resin were used to prepare jute/polyester, glass/polyester and jute-glass hybrid polyester composites by hand lay-up and heat press molding techniques and their mechanical properties were evaluated for different stacking sequences. In Jute/polyester and glass/polyester composites, mechanical properties such as tensile properties, bending properties and impact strength increase with the increases of stacking sequences. In case of jute-glass hybrid composites, the composites which content more glass layer than that of jute layer shows the higher mechanical properties. Water uptake (%) of these composites demonstrate that water absorption rate is initially higher for jute/polyester composite and at a stage it become steady (31.11%), but in case of glass/polyester and jute-glass hybrid composites the absorption rate is very low which is almost less than 1% due to the hydrophobic nature of glass fiber and polyester resin. Soil degradation test of all types of composites were evaluated and the deterioration of the mechanical properties revealed for all the composites where jute/polyester composites showed the higher degree but E-glass/polyester composites retained major portion of its original integrity and their hybrid declined more than glass but less than jute composites. The composites were also radiated under gamma radiation (50 kCi Cobalt 60 Source) of various doses (1-12.5 kGy). It was found that by using gamma radiation, the mechanical properties of the composites were improved
Effective Processing Time & Cost Management of Dyes, Chemicals & Utilities Used in the Combed & Compact Knit Fabric Colouration in the Dyeing Textile Industries
No full textIndustrialization is an inevitable feature of economic intensification in a developing country. The textile dyeing industries uses huge amount of water, steam electricity and substantial quantities of complex chemicals. Textile dyeing house operating in this sector are facing significant challenges to reduce their natural resources and energy consumption. The main purposes of this investigation is to reduce the process time, cost of chemicals, cost of utilities and cost of effluent treatment. In the very beginning of this research, properties of compact and combed yarn were investigated. Then wet processing and process time required for both the compact and combed fabric are compared. Later on different costs associated with the wet processing of both compact and combed yarn fabric are also analyzed. Through this work it is tried to focus on the use of compact yarn fabric instead of combed yarn could be the best possible way to meet the challenges faced by the textile dyeing as well as textile industrie
Acute Philadelphia Chromosome Positive Biphenotypic Leukemia Presenting with Bilateral Orbital Chloroma: A Rare Case Report
Get PDFIntroduction: Chloromas are characteristically formed by the extramedullary soft tissue infiltration by the immature myeloid malignant cells. Such extramedullary masses are most commonly seen in acute myeloid leukemia usually in the M2, M4, M5 subtypes of the AML FAB classification. However, it has been reported to rarely present only in pediatric patients with acute lymphoblastic leukemia.Presentation of the case: We encountered an unusual case of a young male, who presented with proptosis of both eyes followed by fever and fatigue. On evaluation, he was diagnosed to have bilateral orbital chloroma which was due to infiltration by leukemic cells of acute leukemia. Flowcytometry revealed features confirming an acute biphenotypic leukemia. Subsequently, cytogenetic evaluation revealed the leukemic cells to be Philadelphia chromosome positive.Conclusion: To our knowledge, this is the first case of bilateral orbital choloroma due to Philadelphia positive biphenotypic acute lymphoblastic leukemia
Clear Cell Meningioma: A Rare Great Mimicker
Get PDFIntroduction: Clear cell meningioma is an infrequent, agressive variant of meningioma that shows proclivity to the spine. This study aimed to report a case of clear cell meningioma of the lumbar spine and discuss the differential diagnosis, and emphasize the necessity and usefulness of immunohistochemistry for definite diagnosis.Case report: A 23-year-old man admitted to the Department of Neurosurgery with backache existed for about 4 years. Magnetic Resonance Imaging revealed a well-circumscribed intradural and extramedullary mass in the spinal canal at the 5th lumbar vertebra extending to the right neural foramen. The lesion was excised gross totally and diagnosed as “clear cell meningioma”. The patient has been doing well for a year without any sign of recurrence.Discussion: Clear cell meningioma should be considered in the differential diagnosis of the masses located in the spine radiologically. In addition, the histopathological mimickers of it that are composed of clear cells, particularly renal cell carcinoma, should be ruled out by the aid of immunohistochemistry
BRAF Mutation and its effects on Radioiodine Uptake in Patients with Anaplastic Thyroid Cancer
Get PDFContext: Anaplastic thyroid carcinoma (ATC) is poorly differentiated subtype of thyroid cancer which either resistant to radioactive iodine (RAI) therapy or conventional chemotherapy. Each process of the biological characteristics in normal thyroid cells, including iodide uptake by sodium-iodide symporter (NIS), synthesis of thyroglobulin (Tg), expression of thyroid peroxidase (TPO) and receptor for thyrotropin (TSHR), can be an onset stage for emerging thyroid carcinoma. Decrease or absence of NIS mRNA in thyroid carcinomas has well described for resistant to RAI therapy in these patients. Evidence Acquisition: The original articles related to the role of the BRAF mutations on the sodium-iodide symporter functions and radioiodine uptake in patients with anaplastic thyroid carcinoma were found by a search in Scopus, PubMed, Science direct, Springer and some else with an emphasis on literature published in the recent years.Results: The related studies disclosed that mutations in the mitogen-activated protein kinase (MAPK) pathway happen in more than 90% of thyroid cancer. Also serine/threonine-protein kinase BRAF is an important component of the MAPK pathway. Its mutations cause reduction of NIS mRNA compared to tumors with other mutations
Cervical Cancer screening program in Hyderabad and surrounding peri-urban areas, South India: prevalence of high risk HPV subtypes
Get PDFAbstractPurposeCervical screening programs were conducted in urban and peri-urban areas of Telangana and Andhra Pradesh, during the period January 2012–March 2014. Our work was aimed at (I) identifying women with abnormal cervix upon visual inspection and pap cytology testing (II) determining the presence of HPV infection in the individual, along with sub-typing in severe pathologies and cancer, which is an established risk factor for cervical malignancy reported world-over. Methods A total of 530 eligible women (based inclusion criteria for participation) were screened by gynecologist. Pap smears were collected on slides and cervical swab cells were collected in a saline solution for subsequent cytological and molecular analysis. The study was approved by our Ethics committee and informed consent was obtained from the subjects. Personal and medical history of each of the eligible participants was recorded in a well-designed proforma. Data tabulation and statistical analysis was performed using MS Excel and MedCalc software.ResultsOur program witnessed an incremental increase in the number of women accessing screening after counselling for awareness of the importance of testing. A total of 530 women were screened for Pap smear cytology. The mean age of women in the study population was 38.73yrs (+10.82). 16.41% cases showed a normal cytology, 43.39% had an inflammatory smear, 26.22% showed infection, 4.15% showed reactive cellular changes, 6.41% showed atrophy, 0.75% showed ASCUS, 1.88% showed LSIL, 0.37% showed HSIL, 0.37% showed squamous cell carcinoma. Prevalence of HPV in our study population was 14.7% (n=530). 1.8% of our subjects showed the presence of high-risk HPV subtypes; all of them were associated with an abnormal Pap cytology. HPV was shown to be associated with an infectious pap, RCC, ASCUS, HSIL, SCC (p0.05) when compared to normal cytology (p=0.05). ConclusionsAwareness and the importance of cervical examination is low. Health camps need to focus on counselling subjects about its benefits to improve their participation and ensure success of screening programs. The significant association of HPV infection with abnormal pathologies (p=0.05) and the presence of hr-HPV subtypes other than 16 and 18 (that are used for vaccination) draws attention to the need to evaluate the subtypes prevalent in our population and apply this information to cervical vaccination schemes.Keywords Cervical, Pap cytology, HPV, High-risk subtypes Abbreviations HPV- Human Papilloma Virus, hr-HPV-high risk Human Papilloma Virus, RCC-Reactive Cellular Changes, ASCUS- Atypical Squamous Cells of Undetermined Significance, LSIL-Low Grade Squamous Intraepithelial Lesion, HSIL-High Grade Squamous Intraepithelial Lesion, CIN-Cervical intraepithelial neoplasia, SCC-Squamous cell carcinoma
Intraocular Metastasis as the Presenting Symptom of NSCLC and the Role of Bevacizumab: A Case Report
Get PDFIntroduction: Metastasis to the eye is a rare clinical entity accounting for about 2-9% ocular malignancies. Clinical awareness can lead to prompt diagnosis and appropriate management.Case presentation: We here present a case of a 60-year-old patient who visited to several ophthalmologists with the complaint of blurry vision in his left eye. He was diagnosed with anterior uveitis and elevated intraocular pressure. A masquerade syndrome was suspected, and anterior chamber paracentesis was performed, which revealed metastatic non-small cell lung cancer (NSCLC). CT chest revealed a left lung mass with right paratracheal lymphadenopathy. No other evidence of metastatic disease was found on PET/CT scan and MRI of the brain. He received treatment for stage IV lung cancer with carboplatin, paclitaxel, and bevacizumab. The intraocular tumor cell infiltration was treated with intravitreal bevacizumab that resulted in subjective and objective improvement.Conclusion: Metastasis to the eye may present in a masquerade-like fashion as intraocular inflammation. Tumor specific therapy directed locally within the eye may be a component of an overall treatment plan.
Primary Pulmonary Primitive Neuroectodermal Tumor of Lung in a Child
Get PDFIntroduction: Peripheral primitive neuroectodermal tumor (pPNET) arising from lung without involvement of chest wall is very rare. Peripheral primitive neuroectodermal tumor are poorly differentiated, highly aggressive tumor of undetermined histogenesis with a tendency toward early metastasis. Diagnosis needs to be established conclusively by histopathology, immunohistochemistry and molecular studies.Presentation of the cases: A 2 year 10-month old child was investigated for fever, cough and cold and was detected to have right intrathoracic cystic mass on imaging. The mass was excised with possibility of pleuropulmonary blastoma. After excision child was referred to our center for decision on further management. Histopathological examination, immunohistochemistry and molecular study for EWSR gene rearrangement proved the diagnosis of Ewing sarcoma. Metastatic work up for our case was negative. Child is currently undergoing chemotherapy and is asymptomatic.Conclusion: Primitive neuroectodermal tumor (PNET) of lung without chest wall involvement in pediatric age group is a rare occurrence. Available literature suggests highly aggressive nature of such tumor. This case report summarizes the differential diagnosis of such rare pulmonary neoplasm in children and role of immunohistochemistry and molecular studies to establish the diagnosis conclusively
Comparative Analysis among Different ZnO Nanoparticles Synthesized by Different Techniques
Get PDFSemiconductor oxides were synthesized and systematically examined on 100 % cotton fabric to optimize the properties. Nano-technology is employed in this research work to form nanoparticles of semi-conductor oxides. Four samples were synthesized by using different methods and dyed to find the effective one. Different characterization techniques are used to characterize nanoparticles e.g. X-ray powder diffractometer, Energy dispersive X-ray spectroscope (EDS, EDX or EDXRF) and SEM images. By examining diffraction pattern and SEM images homogeneity, crystalline phase, transparent finishing process and unit cell dimensions are found. ZnO-3 (sample 3) (TEA 0.025M) treated cotton is revealed to have unique properties and implied a transparent finishing process