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Synthesis and Characterization of Novel Oxoazetidine containing Phenyl Imidazole Carbamates
Get PDFThe pharmacological important of nitrogen containing heterocyclic of novel Oxoazetidine containing Phenyl Imidazole Carbamates 8(a-d) which are synthesize from reaction between aldehyde, aniline and monochloro acetyl chloride via Schiff base intermediate which on under goes with reaction of acid, azide and alcohols. The Oxoazetidines were established by IR, 1H NMR, 13CNMR and mass spectral analysis
Treatment of Post Traumatic Internal Carotid Artery Pseudo Aneurysm with Intravascular Coil Embolization
Get PDFIntroduction: Vascular complications such as bleeding and pseudoaneurysm following an endoscopic trans-sphenoidal approach for the basal skull pathology are rare but when it occurs it brings a significant risk of morbidity and mortality along with it. Intraoperative bleeding can be managed with manual packing and in case of pseudoaneurysm formation, it can be successfully managed with endovascular coiling.Case presentation: One month after an endoscopic sphenoidal resection of mucocele. A 49-year-old female presented with massive left sided epistaxis due to formation and rupture of pseudoaneurysm at left cavernous segment of internal carotid artery. She was managed with multiple coil embolization of pseudoaneurysm.Conclusion: A patient with pseudoaneurysm formation following an endoscopic trans-sphenoidal approach for a mucocele resection was successfully managed by the emergency endovascular coiling, with complete obliteration of the aneurysm and bleeding while maintaining the vessel patency. This approach is less invasive, quick as well as safe and do not require long term anticoagulation. However, long term follow and larger sample are required to evaluate its efficacy
Acute Myeloid Leukemia Presenting as Granulocytic Sarcoma (Chloroma) of the Tongue: A Case Report
Get PDFChloroma or Granulocytic Sarcoma or Myeloid Sarcoma or Myeloblastoma is a tumor composed of immature myeloid precursor cells or blasts. It is an extra medullary manifestation of AML, which is extremely rare but well documented. It can herald, follow or occur with a diagnosis of primary AML. It can also be seen in relapse [1]. The usual sites of involvement are skin, soft tissue and lymph nodes. Intra oral myeloid sarcoma is infrequent and particularly chloroma in the tongue is further uncommon. A thorough review of literature yielded only three reported cases of chloroma of the tongue [2-4]. In this case report, we describe a case of a 36-year-old female who presented with two weeks of dysphagia due to a large tongue lesion accompanied by pancytopenia. The tongue lesion was strongly suspicious of a chloroma. Bone marrow biopsy confirmed a diagnosis of AML and a resolution of the chloroma was observed with induction chemotherapy for AML
An Instigation to Green Manufacturing: Characterization and Analytical Analysis of Textile Wastewater for Physico-Chemical and Organic Pollution Indicators
Get PDFSevere environmental pollutions are contributed by textiles at an alarming rate. Proper treatment of wastewater before discharge is mandatory for maintain our ecological balance. Pollution levels of textile effluent has been investigated and analyzed in this research. Effluent samples from different areas of textile processing industries in Bangladesh were collected and analyzed. A total forty sample were studied and characterized their result ranged are temperature, pH, Total Dissolved Solid (TDS), Dissolved Oxygen (DO), Chemical Oxygen Demand (COD) and Biological oxygen demand (BOD5). Standard sample collection procedures was followed to collect samples of six months and analyzed immediately temperature, pH TDS by pocket size Thermometer, pH and TDS meter. To sum up, textile effluent contains high Temperature, pH, TDS, COD and lower DO which threatens aquatic lives live. It has been acclaimed that, it is quite unsafe for this discharge into water body to continue. The ecological and human health safety of continual discharge of this textile effluents into surface water are undoubtedly under threat
Scrutinization of Poly(ethylene-co-ethyl acrylate)/Poly(methyl acrylate) and Zein-based Nanocomposite
Get PDFIn this study, a blend of poly(ethylene-co-ethyl acrylate) (PEEA) and poly(methyl acrylate) (PMA) was prepared using solution technique. Later the blend was reinforced with 1-5 wt.% zein (corn protein) as filler. Mechanical, thermal and morphological characteristics of PEEA/PMA/Zein nanocomposite were measured using suitable techniques. The analysis of the fractured surfaces by scanning electron microscope showed that the zein was dispersed in the form of elliptical grains. Morphology of PEEA/PMA/Zein nanocomposite illustrated homogeneous granular dispersion with no phase separation due to blend miscibility and compatibility with zein nanoparticles. Tensile strength of PEEA/PMA/Zein 1-5 nanocomposite was increased from 30.1 to 45.8 MPa relative to neat blend (24.7 MPa). Similarly Young’s modulus of PEEA/PMA with 5 wt. % zein filler was 31% higher than the neat blend. The dynamic mechanical thermal analysis (DMTA) results depicted shift in tan δ peaks of blend at 187 °C to 219 °C in PEEA/PMA/Zein 5 nanocomposite
Xanthogranulomatous Cholecystitis Mimicking as Gallbladder Carcinoma：A Caution for Hepatobiliary Surgeon
Get PDFBackground: Xanthogranulomatous Cholecystitis (XGC) is a destructive inflammatory process of the gall bladder which can rarely extend into neighboring structures mimicking advanced carcinoma of the gall bladder. To the best of our knowledge six such cases have been reported in medical literature in which Xanthogranulomatous cholecystitis had lead to involvement of surrounding structures. Preoperative diagnosis of such a lesion remains difficult and most of such cases are diagnosed postoperatively following resectional surgery. Case Presentation: A 40 years old lady was admitted with the clinical picture of cholecystitis and gastric outlet obstruction. Ultrasonography showed gall stones with pericholecystic collection communicating with GB lumen. CT scan showed a mass arising from gallbladder with pericholecystic fluid with gross distension of the stomach. LFTs, CEA and CA 19-9 levels were within normal limits. Endoscopy of the stomach showed an apparently non-epithelial rounded mass projecting into gastric lumen causing partial obstruction of the gastric outlet. On exploration, a firm mass involving gallbladder and stomach was identified for which en-bloc extended cholecystectomy and Billroth-II gastrectomy was performed. Histopathology of the specimen revealed XGC with secondary involvement of pylorus of the stomach.Conclusion: Given the rarer preoperative diagnosis of XGC, which morphologically and radiologically mimics carcinoma, such cases should be managed aggressively. A brief literature review has also been discussed
Benign Pulmonary Metastasizing Leiomyoma: A Case Report
Get PDFIntroduction: Benign metastasizing leiomyoma (BML) is a rare disease, the first case of BML was reported by Steiner in 1939. It can affect any age group ranging from 30 to 75 years, but most commonly found in late childbearing period. Leiomyoma of the uterus can metastasize to different organs but lung is the most common site, hence the term pulmonary benign metastasizing leiomyoma (PBML) is used. PBML is mostly diagnosed incidentally on imaging studies for other conditions. It can occur many years after hysterectomy for Leiomyoma of uterus.Presentation of the cases: We report a case of a 51 years old lady with chronic cough and pulmonary nodules on a computerized tomography (CT) scan. She was referred to our hospital for the management of the probable metastatic cancer. Her diagnosis was challenging but a past history of hysterectomy, radiological findings and the histopathology helped us to diagnose this rare condition of benign metastasizing leiomyoma (BML).Conclusion: Pulmonary benign metastasizing leiomyoma is rare benign disease. It should be considered as the probable diagnosis in a female patient with pulmonary nodules and a previous history of surgery for leiomyoma of uterus. Pathological differentiation from leiomyosarcoma and other malignant metastatic condition is essential. Prognosis of PBML after surgical and/ or hormonal treatment is good
Prevalence and Characterization of Methicillin-Resistant Staphylococcus Aureus Isolates from Commonly Shared Public Objects
Get PDFThe prevalence, characteristics and antimicrobial susceptibility of methicillin-resistant Staphylococcus aureus (MRSA) on vehicular gate passes and ATMs, two most likely shared public objects, at Nnamdi Azikiwe University Awka, Anambra State, Nigeria were studied. A total of 390 of plastic gate passes and 364 of ATMs within the premises of Nnamdi Azikiwe University Awka, Anambra State, Nigeria were sampled for bacterial isolation during a period of 24 weeks. Surface swabs of samples were collected and used for S. aureus enrichment and isolation. Presumptive positive colonies were further identified Gram staining test, catalase test and coagulase test. S. aureus were screened by mecA gene amplification with multiplex PCR. Only the mecA-positive S. aureus isolates were selected for antimicrobial sensitivity assay. Antibiotic sensitivity pattern of isolates to different antibiotics was tested by disk diffusion reference method. S. aureus was isolated from 30% (117/390) of plastic gate passes and 44.8% of ATMs (163/364). With mecA amplification, 14.5% and 20.2% of the S. aureus isolates from gate passes and ATMs were identified as MRSA, respectively. Multidrug resistance to ampicillin, ceftriaxone, ciprofloxacin, erythromycin, gentamicin, oxacillin, penicillin G, rifampin, streptomycin, and tetracycline was recorded among the isolated MRSA from both sources. Implicated MRSA in samples present severe health-risk potentiality together with significant extensive antibiotic resistance
Cellular Flow Cytometric Studies
Get PDFThis review focuses on flow cytometric studies at the single cell level. Currently, flow cytometry is used to analyze DNA content, cell cycle distribution, cellular viability, apoptosis, calcium flux, intracellular pH and expression of cell surface compounds in targeted cell populations. Our criteria for the selection of research papers for this review were focused on those that show current cellular applications of flow cytometry