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Effective Interventions for Preventing Burnout in Health Education Students
Get PDFThis article aims to investigate effective interventions to reduce burnout in health education students. A comprehensive electronic literature search of PubMed and Google Scholar identified articles discussing the prevalence and effects of burnout in health care providers and students, as well as interventions to reduce burnout and improve the quality of life of health education students. The findings suggest pass-fail grading, physical exercise, mindfulness training, and mental health programming significantly reduce burnout among health education students. Significant variability in both intervention design and outcome measurement highlights the limitations of the findings and underscores the need for future research. Effective burnout prevention in medical students may positively impact the health care workforce, improving patient outcomes and workforce stability
Evolution of BTK inhibitors
Get PDFThe purpose of this clinical review evaluates the evolution of bruton’s tyrosine kinase (BTK) inhibitors in becoming the standard of care in treating chronic lymphocytic leukemia (CLL). The first-generation BTK inhibitor ibrutinib has demonstrated superior efficacy over traditional chemotherapy in several randomized clinical trials in terms of progression free survival (PFS). However, due to cardiovascular toxicities of atrial fibrillation (afib), hypertension (HTN), and bleeding, have led to drug discontinuation. Second-generation BTK inhibitors, acalabrutinib and zanubrutinib have demonstrated reduced rates in cardiovascular toxicities due to improved BTK receptor selectivity, as seen in three head-to-head ibrutinib clinical trials. The emergence of BTK mutation C481S had led to the creation of noncovalent or reversible BTK inhibitors, such as pirtobrutinib. Clinicians need to be able to understand when and how to order testing that proves a patient has developed BTK resistance. The emergence of another mutation, that is not related to C481S, called non-C481S is of clinical interest. BTK protein degraders are in clinical development to test against C481 and non-C481 mutations
Management of Electrolyte Abnormalities in the Emergency Department
Get PDFThe objective of this article review is to discuss standard treatment options and review emerging therapies for the more common electrolyte abnormalities. The number of emergency departments (ED) in the United States has declined over the past 15 years, which has created overcrowding. This makes it more difficult to prioritize patients based on severity. The importance of this topic is to assist providers in taking quick action on patients presenting with critical electrolyte levels in busy EDs. A literature search using PubMed from 2019 to 2024 identified numerous articles that supported the purpose. This review will discuss the various electrolyte disorders and the treatment commonly seen within the first few hours in the emergency department (ED). The implications of this research show that standard treatments are consistent among numerous authors. Providers will likely find the same protocols in most facilities and the patients can expect to be treated relatively the same despite hospital location. Future research should involve treatments without intravenous crystalloids due to manufacturing shortages, additional medications to shift or excrete electrolytes, and action plans to prevent patients from repeated visits for the same electrolyte disturbances. The lack of availability of the new potassium binders at EDs due to increased cost may also be researched
The Role of GLP-1RAs in Depression among Patients with Metabolic Conditions
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The regular co-occurrence of depression with metabolic syndrome (Mets) results in complicated treatment circumstances and raises cardiovascular diseases and type 2 diabetes risks. GLP-1RAs demonstrate potential as an innovative treatment for depression because they have both anti-inflammatory properties and neuroprotective capabilities. This evaluation examines the advantages and results of GLP-1RAs in treatment effectiveness compared to CBT among patients with MetS. The research used PubMed and CINAHL databases to find peer-reviewed studies from 2021 until 2025. The research included the search terms “GLP-1 receptor agonists” together with “depression,” “metabolic syndrome,” and “cognitive behavioral therapy,” among other relevant terms. Applying GLP-1RAs generates successful depressive symptom reduction in 55-60% of MetS patients, above what CBT achieves in 40% while simultaneously improving HbA1c levels. The study presents several constraints due to small participant numbers, high financial requirements, and regulatory restrictions against extended use. Randomized controlled trials must take place on a large scale before determining the effectiveness and safety of using GLP-1RAs as dual therapeutic agents. Future studies should determine the right dosage combination of GLP-1RAs with CBT to improve patient results.
Keywords: Metabolic syndrome, Depression, GLP-1RAs, Neuroinflammation, CB
CARs and TRUCKs: Driving a Paradigm Shift in Hematologic Malignancies
Get PDFHematologic malignancies account for a significant number of annual cancer diagnoses and deaths across the globe. Historically, the prognosis for relapsed and/or refractory disease after standard therapies, such as chemotherapy and/or radiation, was poor. Chimeric antigen receptor (CAR) T-cell therapy offers an additional treatment option. While promising, this type of immunotherapy also comes with potentially severe side effects, toxicities, and limitations. A better understanding of the development, administration, and management of patients undergoing treatment can provide the general clinician with the knowledge to assist within a multidisciplinary team to ultimately improve patient outcomes
Analyzing the Use of Quantifying Patient Acuity on Medical Surgical Units and Its Impact on Nursing Care
Get PDFUsing existing data, qualitative research and quantitative research, this paper is an analysis of the literature regarding the use and effects of assessing patient acuity within the medical surgical population. A patient acuity tool is a system used in health care to determine the complexity of a patient. Current methods and studies of implementing a patient acuity tool are presented and their results are analyzed to determine aspects that have improved, as well as negatively impacted, the delivery of nursing patient care. The need for a standardized patient acuity tool is linked to better patient outcomes, yet a protocol is not standardized. Barriers to implementing a patient acuity tool are addressed, along with the implications that can occur when a patient acuity tool is not used. This literature review emphasizes the importance of assessing patient acuity to better allocate resources and improve patient care. Potential solutions relate back to nurse leadership and establishing a positive workplace culture. If patient acuity tools are implemented, then resources can be better allocated to achieve better patient outcomes
Discovering the Roots of Terror: Understanding the Relationship Between Terrorism and Corruption
Get PDFThis research investigated the relationship between terrorism and the factors of corruption, democracy, and human development by using a regression analysis with data collected from Vision of Humanity’s Global Terrorism Index (GTI), Transparency International’s Corruption Perceptions Index (CPI), the United Nations Human Development Index (HDI), and the Freedom House’s Global Freedom Scores. Based on previous research and other literature, it was hypothesized that corruption is a significant cause of terrorism. Using data from 2018 to 2022, 158 countries were included in the analysis. Expanding on the research, four case studies (Somalia, Israel, Liberia, and Georgia) were chosen to evaluate the countries’ anti-corruption practices. The regression was significant at the .95 level, showing that the data was statistically significant. R 2 = .049, meaning that 4.9% of the variance in terrorism is explained by corruption, democracy, and human development. Since R 2 = .049, it was concluded that some other factors influenced terrorism
Chronic Absenteeism: A Case Study in a Central Virginia High School Investigating Student Habits and Potential Interventions
No full textAbstract
The purpose of this single case study was to discover and determine the contributing factors for chronic absenteeism for high school students at a rural Central Virginia high school in order to discover potential solutions to increase attendance and to combat chronic absenteeism. An additional factor considered was habits that may have formed during the COVID-19 pandemic, which may have led to an increase in chronic absenteeism rates. The theory that guided this study was Bronfenbrenner’s (1979) Ecological Systems Theory, as it directly addressed how a child relates and reacts to their environments based upon their interactions. The participants in this single case study included semi-structured interviews with English (n=3) and math teachers (n=3), a focus group with the school-level attendance team (n=4), and a parent questionnaire (n=24). Four major themes emerged from the triangulation and analysis process: (1) student engagement and motivation; (2) student well-being; (3) school climate; and (4) incentives and relational supports. Important subthemes pertaining to the importance of education, student mental health, the effects of COVID-19, school-based incentives, apathy, family environments, partial absences, teacher-based incentives, homelife, parentified students, caregiver attitudes toward school, and teacher-student relationships were also included in each of these major findings. These findings demonstrated that a complex web of personal, familial, and systemic factors—rather than merely student or family irresponsibility—influenced chronic absenteeism. The study also demonstrated that external factors, particularly the aftermath of COVID-19, significantly impact school climate, along with possible caregiver attitudes toward education that result from previous negative school encounters. The three main incentives and supports that may address these pervasive issues are strong teacher-student interactions, school-based incentives, and teacher-based incentives. The study also found that a positive, relationship-focused approach was the most effective way to boost attendance and create a truly supportive learning environment. The findings from these studies, as well as the supporting information included in the main conclusions of this particular case study, enable suggestions to be made that can be utilized at the local school and division level to help combat chronic absenteeism.
Keywords: chronic absenteeism, parent support, attendance interventions, attendance incentives, case study, ecological systems theory, mesosystem, microsystem, accreditatio
