International Journal of Ayurvedic Medicine
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The Effect of Kokilaksha Ghanavati & Guduchi Ghanavati in the management of Vatarakta (Gout) – A Randomised Clinical Study
Get PDFBackground: Amid the joint conditions outlined in the texts of Ayurveda, Vatarakta (Gout) is the most common type of inflammatory arthritis; its rising global prevalence is the outcome of rapid modernization and faulty dietary practices, and has a significant detrimental effect on health, quality of life and productivity. Objective: To compare the efficacy of Kokilaksha Ghanavati and Guduchi Ghanavati in Vatarakta (gout). Materials and Methods: The present trial was a randomised clinical study. Computer-generated randomization and participants fufilling the criteria of vatarakta symptoms were recruited in two groups. Group A intervened with Kokilaksha Ghanavati and Group B with Guduchi Ghanavati for 14 days, with follow-up on 7th day and assessed with subjective and objective parameters. Results: The findings of the research revealed that Group B had statistically significant improvement compared to Group A on the Sandhi shoola (joint pain), sankochan (stiffness), visual analog scale (VAS) score, while Group A considerably outperformed Group B with regard to improvement in Sandhi Shotha (joint swelling). Daha (burning sensation), sparsha-asahatva (tenderness) and serum uric acid showed comparable improvements in both the groups. Conclusion: Guduchi Ghanavati proved to outscore Kokilaksha Ghanavati in the management of Vatarakta. However, Kokilaksha Ghanavati showed major improvement in key feature of the disease (shotha-86.21%), along with visible improvement in other parameters as well. The positive impact of it on vatarakta is also undeniable.
Ten Names of the Naga Sannyasi Tradition
Get PDFThe "Ten Names of the Naga Sannyasi Tradition" delves into the historical and organizational life of the Naga Sannyasis, a venerated spiritual fraternity in India. Based on old traditions, the Dashnam Sannyasis were restructured by Acharya Shankar to boost their strategic and spiritual value. The narrative unfolds the complex evolution of the Naga Sannyasis, from their early formation as Paramahansa Sannyasis found in Upanishads to playing a pivotal role in protecting society at the time of foreign invasions. Acharya Shankar\u27s systematic reorganization of these ascetics into a well-structured framework, similar to a contemporary military organization, ensured both the sustenance of spiritual beliefs and the safeguarding of Hindu society. The article explores the origin and functions of the different Akharas—like the Ahwan, Atal, and Mahanirvani Akharas—founded by prominent leaders. These Akharas were not only centers of spirituality but also centers of military training during pivotal moments in Indian history. Gradually, the number of Akharas increased to fourteen, each having its own traditions and worship gods. The Naga Sannyasis, with their rigorous organization and structural abilities, managed to maintain their traditions and even remain an indispensable part of Hindu society, mainly in the Kumbh Mela. Through this article, one can deeply understand the sacred, organizational, and protective services of the Naga Sannyasis throughout centuries
The Role of Government and Media in the Organization of Mahakumbh
Get PDFThe Mahakumbh Mela, an important religious and cultural festival conducted in Prayagraj, Uttar Pradesh, draws millions of pilgrims and tourists from all over the globe. The 2025 Mahakumbh is being arranged with widespread assistance from the government and media to make it a successful event. The Uttar Pradesh government has also made many of its services digital, such as introducing the Mahakumbh Mela App, AI-driven chatbots, digital lost and found, and QR codes for the ease of accessibility. These technologies provide real-time information on events, improved navigation, and emergency services. Additionally, AI-enabled cameras and digital mapping through Google have enhanced the event experience by making it safer and more accessible. A strong infrastructure, in the form of transport facilities such as special trains, buses, and flights, has been provided to deal with the influx of visitors. Ambulances and hospitals are positioned throughout the venue to take care of health issues. The media complex, supported by cutting-edge technology, broadcasts live and provides updates to the international audience so that individuals across the globe get to experience the majesty of the event. The joint effort of the government and media has transformed the Mahakumbh into a global cultural spectacle that is not only a religious event. The article here analyzes the role of both these industries in ensuring the success of the Mahakumbh Mela and its broader influence on global viewers
Safety and Good Governance
Get PDFThe Mahakumbh is a massive religious and cultural gathering held at Prayagraj, India, attracting millions of devotees from across the globe. The state government has meticulously planned and implemented numerous safety and infrastructure measures to ensure the smooth and secure operation of the Mahakumbh 2025. Over 50,000 security personnel, including police, home guards, and specialized teams such as NDRF and SDRF, are deployed to manage the large-scale event. Cutting-edge technology, including over 2700 AI-powered CCTV cameras and various other surveillance systems, is employed for real-time monitoring. The fair area is equipped with essential amenities, such as fire stations, water police control rooms, and fire-fighting robots, ensuring prompt response to emergencies. The state government has also focused on improving the infrastructure, with the construction of new bridges, roads, and power sub-stations. A significant emphasis is placed on improving transportation with upgrades to Prayagraj Airport, railway stations, and roadways to handle the influx of devotees. Additionally, F.R. codes are being introduced for easy access to essential services such as emergency healthcare, food, and accommodation. The preparations for Mahakumbh 2025 reflect a fusion of tradition and modernity, with technological advancements enhancing the experience of the devotees. This strategic blend ensures the efficient handling of the largest religious congregation in the world
Comparative evaluation of the efficacy of Hydrocortisone suppository and Durvadi Gudavarti in Raktarsha – A randomized controlled clinical trial
Get PDFBackground: Arsha, which is correlated to Hemorrhoids according to contemporary sciences, is a disease of yore. It is one of the most prevalent illnesses nowadays. It is the most common cause of bleeding per rectum in adults and the fourth leading diagnosis made in the gastrointestinal outpatient department. Aim and Objectives: This study aimed to compare the efficacy of Durvadi Gudavarti and Hydrocortisone acetate-based suppository in the management of Raktarsha (Bleeding Piles). Methods- A randomized active-controlled double-blind superiority clinical trial that involved 130 subjects between the age group of 20 to 60 years of Raktarsha, were assigned into two groups with equal allocation. The Control group (Group C) received Hydrocortisone suppository and the Experimental group (Group E) received Durvadi Gudavarti for rectal administration twice daily (12 hourly) after the proper evacuation of the bowel, for 2 weeks. Clinical evaluations were performed at Baseline, 5th, 10th, 15th day post-inclusion. The main endpoint was the proportion of subjects with complete clinical response and reduction in the size of pile mass measured using a transparent millimeter ruler on the 15th day. Results- Groups were homogeneous in terms of demographic and baseline characteristics. The Durvadi Gudavarti was found to be 34% and 32% more efficacious than the Hydrocortisone acetate-based suppository in terms of reduction in the size of pile mass and bleeding PR respectively. Interpretation & conclusions- Durvadi Gudavarti as rectal administration showed a significant advantage over a widely used standard treatment in the management of Raktarsha.
Keywords: Raktarsha, Bleeding Piles, Durvadi Gudavarti, Haemorrhoids, Hydrocortisone suppository, Ayurvedic suppository
To Evaluate the Efficacy of Add on Treatment of Oral Drug Formulation With Agnikarma in the Management of Jaanu Sandhigata Vata W.S.R. To Osteoarthritis of Knee Joint – a Randomized Controlled Trial
Get PDFBackground: Recent estimates suggest that OA affects approximately 7.6% of the globalpopulation, with knee OA being especially common among older adults. The combined approach of Agnikarma and oral drugs holds significant promise as an effective option forosteoarthritis. Objective: To Evaluate the Efficacy of Add on Treatment of Oral Drug Formulation with Agnikarma in The Management of Janu Sandhigata Vata W.S.R. to Osteoarthritis of Knee Joint. Materials and Methods: 40 subjects diagnosed with Janu Sandhigata Vata after fulfilling inclusion criteria were enrolled in the study. Agnikarma performed every 7th day (4 sittings) after obtaining informed consent according to the randomized groups i.e., Control group (Agnikarma) and Trial group (Agnikarma along with Oral drugs). The assessment parameters i.e., Pain, Tenderness, Swelling, Crepitus, ROM and Kellgren and Lawrence classification of Osteoarthritis were assessed from baseline and at different time points. Results: The results demonstrated significant improvements in the Trial group receiving combined treatment in all the parameters. Pain, Tenderness and ROM showed statisticallysignificant improvements, with the Trial group consistently outperforming the Control group. Conclusion: The Trial group (Agnikarma combined with oral drugs) demonstrated superior efficacy across most clinical parameters in improving pain, tenderness, and functional outcomes (range of movement), suggesting that the combined treatment provides significant benefits over Agnikarma alone in the management of Janu Sandhigata Vata. Clinical Significance: This study highlights the potential of a combined approach of Agnikarma and oral drugs as an effective intervention for osteoarthritis, providing meaningful improvements in pain and functionality over a short duration.
Kushmanda ghrita - A Nano Formulation: Physico-chemical and Pharmaceutical Evaluation
Get PDFAyurvedic ghee-based formulation Kushmanda ghrita (KG) is prescribed for various psychological disorders. Ayurvedic products’ quality has been the prime concern over years. There is a lack of literature regarding standardisation of KG and quantification of glabridin, a constituent of licorice, which is part of KG. Ghee is considered an excellent carrier. Hence, this study aimed to prepare, standardise KG, and quantify glabridin using HPLC and to evaluate the particle size of the KG. KG was prepared according to classical texts, subsequently, the KG and Desi cow ghee (DG), which are employed for preparing KG, were subjected to assessment of physicochemical parameters. The amount of glabridin in KG was quantified using HPLC method. The particle size was analysed for the prepared KG. Investigation revealed that there were insignificant differences in physicochemical parameters of KG and DG, and they are within the acceptable limits. Glabridin was extracted by petroleum ether and methanol (70%) solvent system, quantified by HPLC method, and found to be 0.1873±0.003 mg/g of KG. Further, the particle size analysis revealed that the KG sample was showing a varying globule size; the maximum volume occupancy of 43.6%v/v gives a globule size of 260.5nm, and hence it is said to be a Nano formulation. In summary, the quality of KG was assessed in terms of physicochemical parameters. The glabridin was quantified using HPLC by optimising extraction procedure. The particle size of KG was analysed and found to be in Nano region. The outcomes of this study may be helpful in further studies on the molecular mechanism, pharmacodynamics and pharmacokinetic and drug interaction studies of KG
Evaluation of hydration and unctuousness of skin in female volunteers of Ras sara- asara using non-invasive objective method: A cross sectional analytical study
Get PDFBackground: Ayurveda classifies individuals based on Dhatu Sarata, where Rasa Sarata (superior quality of Rasa Dhatu) is associated with better skin hydration and unctuousness. However, objective scientific validation of this concept remains limited. This study aimed to evaluate skin hydration and unctuousness in female volunteers as Rasa Sarata and Rasa Asarata by using a non-invasive digital moisture meter. Methods: A cross-sectional analytical study was conducted on 82 healthy female volunteers aged 20–28 years, categorized into Rasa Sarata (n=41) and Rasa Asarata (n=41) groups based on standard Ayurvedic parameters. Skin hydration and oil levels were measured at five anatomical sites (face, forehead, arm, opisthenar, and ocular region) using the SK-IV Digital Moisture Meter. Data were analyzed using the Mann-Whitney test to compare hydration and unctuousness between the groups. Results: Rasa Sarata individuals exhibited significantly higher hydration and oil levels across all measured sites compared to Rasa Asarata individuals (p < 0.05). Regional variations were observed, with the highest hydration and unctuousness levels in the facial and ocular regions. Conclusion: This study provides scientific validation for Ayurvedic Rasa Sarata and Rasa Asarata classifications by demonstrating measurable differences in skin hydration and unctuousness. The findings highlight potential applications in personalized skincare, integrating Ayurvedic diagnostics with modern bioengineering tools for dermatological and cosmetic advancements. Further research incorporating biochemical markers and Ayurvedic interventions can enhance our understanding of Rasa Dhatu’s role in skin physiology
Efficacy of Add-on Ayurveda Treatment Protocol in the Management of Subclinical Hypothyroidism: A Pilot Randomized Controlled Clinical Trial
Get PDFBackground: Subclinical hypothyroidism, a common endocrine disorder characterised by elevated serum thyroid-stimulating hormone (TSH) levels while maintaining normal free thyroid hormone levels. While levothyroxine remains the standard treatment, it can sometimes lead to adverse effects. This randomized controlled trial evaluated the efficacy of Integrative Ayurveda Treatment Protocol (IATP), including dietary modifications, yoga and the polyherbal formulation Shiva gutika, alongside conventional therapy in managing Subclinical Hypothyroidism. Methods: Thirty patients of subclinical hypothyroidism (TSH: 5 to 50 mIU/L) aged 18–60 years were randomly assigned to the Standard Treatment Protocol for Subclinical Hypothyroidism (STP) and IATP groups. The STP received standard levothyroxine treatment along with dietary and lifestyle guidance, while the IATP group followed an add-on protocol including Ayurveda protocol, which includes polyherbal combination shiva gutika, ayurveda diet and yoga along with add-on conventional medicine. Outcomes were assessed using serum TSH, T3 and T4 levels on 0th and 60th day and anthropometric measures, ZULEWSKI score and WHO quality of life BREF on 0th , 30th and 60th day. Statistical analyses were performed using SPSS v25, with p<0.05 considered significant. Results: The IATP group exhibited significant reductions in serum TSH levels (p<0.0001) compared to the STP group. Improvements were also observed in IATP group in ZULEWSKI scores (p<0.0001). Anthropometric measures, weight, BMI and WHOQOL-BREF scores showed favorable trends within the IATP group, with marked quality-of-life improvements by day 60 (p<0.007). No adverse events were reported. Conclusion: The Integrative Ayurveda treatment protocol demonstrated enhanced efficacy in managing subclinical hypothyroidism when compared to conventional therapy alone, highlighting its potential as a safe and effective adjunct. Larger studies are recommended to validate these findings
Phytochemical Profile, in vitro Antioxidant Potential and HPTLC Fingerprinting of Acalypha indica Linn. Leaves
Get PDFThe present study aims to standardize and evaluate bioactive profiling of Acalypha indica L. leaves through pharmacognostic parameters, phytochemical screening and High-Performance Thin Layer Chromatography (HPTLC) analysis. Comprehensive standardization was carried out using physicochemical constants, including moisture content, total ash, acid-insoluble ash, and extractive values, by pharmacopoeial guidelines. Macroscopic and Microscopic analyses confirmed key diagnostic features of leaves for identification and quality control profiling. Preliminary phytochemical screening of the ethanolic extract revealed the presence of bioactive constituents such as flavonoids, alkaloids, tannins, glycosides, and phenolic compounds. Antioxidant activity was assessed using in vitro assays including DPPH, ABTS, Superoxide, Hydroxyl radical, Nitric Oxide scavenging, and CUPRAC methods. The extract exhibited significant free radical scavenging potential, particularly in the CUPRAC and Superoxide assays. HPTLC analysis showed the best separation of bands at different retention factors (Rf) when using a solvent system of Toluene: Ethyl acetate: Glacial acetic acid in the ratio of (7:2:1 v/v/v). The quantitative estimation revealed that 10 mg of the ethanolic extract of Acalypha. indica L. contained 13.90 µg of kaempferol