International Journal of Ayurvedic Medicine
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Assessment of correlation of Gadget Addiction with different Manas Prakriti among children: An observational study
Get PDFBackground: Prakriti plays an important role in the maintenance of a person`s health. It also influences the life style and choices of a person. Any type of addiction is related to choosing the unwholesome thing over the wrong; hence, it is necessary to study the correlation between gadget addiction and Prakriti. Objectives: This study aims to investigate the correlation between gadget addiction and various Prakriti types among children, shedding light on potential connections between Manas Prakriti and the prevalence of gadget addiction in this demography. Methods: A cross-sectional observational study was conducted on 200 school-going children using Young’s internet addiction test scale and Prakriti examination with the Ayusoft software. Statistical analysis, including t-tests, was employed to assess the correlation between gadget addiction and different Prakriti types. Result: The examination of participants\u27 Prakriti revealed that 52% exhibited Rajas Prakriti, 37.5% displayed Tamas Prakriti, and 10.5% showed Satvik Prakriti. The statistical analysis demonstrated a robust t-value of 22.79 and a highly significant p-value (<0.01), indicating a strong and statistically significant correlation between gadget addiction and Manas Prakriti among the studied children.Conclusion: The findings suggest a compelling association between gadget addiction and specific Prakriti types, particularly Manas Prakriti. This insight contributes to our understanding of the intricate relationship between mental constitution and technology-related behaviors in children. Further research exploring the nuanced aspects of this correlation could inform targeted interventions and preventive measures for gadget addiction among children
Effects of the Yogic Practice of Surya Namaskar and the Little Millets Diet on the Management of Type-2 Diabetes Mellitus
Get PDFIntroduction: Excess blood glucose levels are a hallmark of diabetes mellitus, a metabolic disease that affects the body\u27s metabolism. This illness has the potential to seriously damage the heart, blood vessels, kidneys, eyes, nerves, and heart over time. Aim: The aim of present study is to find how Surya namaskar and little millet affected the quality of subjects with type 2 Diabetes mellitus. Methodology: A randomised control study at SSH Hospital, BHU, Varanasi was conducted in three groups of participants with type 2 diabetes: Surya namaskar alone (Group A) and Surya namaskar with little millet (Group B) as a diet in the management of Diabetes mellitus in comparison to control group in which no intervention is provided (Group C). Study has assessed the subjective (increased thirst, frequent urination, increased hunger, weight loss, fatigue, blurred vision, and healing) and objective parameters (Blood sugar, Fasting, Random, Postprandial and HbA1c). Result: According to study, the combined use of Surya namaskar and little millet diet has been found to be highly significant in lowering symptoms of increased thirst, frequent urination, increased hunger, weight loss, fatigue, blurred vision, and healing. The results showed that, after a month, both Group A and B were able to lower their fasting blood sugar levels significantly. But random and postprandial glucose levels and HbA1c are significantly decreased in Group B only. Conclusion: The study results concluded that if both the Surya namaskar and little millets are intervened to Diabetes mellitus patient, it plays a significant role in managing diabetes
Uloga Suttigai (Metal Cauterization) and Pattikattal (Bandaging) with Kunthriga Thailam in the Management of Kuthikaal Vatham (Haglund’s disease) – A Case Report
Get PDFHaglund’s disease is the term used to describe posterosuperior calcaneal prominence linked with pain in the retrocalcaneal region. Most of the patients suffering from this condition do not profit from conservative treatment and consequently undergo surgical treatment which results in long recovery period and vary in results. In Siddha system of medicine, Haglund’s disease is referred to as Kuthikaal Vatham. Suttigai is a Para surgical procedure used in treating chronic conditions and various thailam (medicated oil) are used in the management of Vatha Noigal (disease caused due to vitiated vatha humour). As Uloga Suttigai (Metal Cauterization) and Pattikattal (Bandaging) provides significant relief in this condition and not been subjected to scientific evaluation yet, this study reports the effectiveness of Uloga Suttigai and Pattikattal with Kunthriga Thailam in the management of Kuthikaal Vatham in a 58-year-old male patient who reported with complaints of swelling and progressive pain behind the right heel, aggravating on walking after rest and more during ambulation for the past 2 years. He was diagnosed with Kuthikaal Vatham and treated with this treatment modalities. The American Orthopaedic Foot and Ankle Society (AOFAS) Ankle-Hindfoot Scale was used before and after treatment to evaluate its effectiveness. Following treatment, AOFAS Ankle-Hindfoot Score improved from 18% to 95%. The pain, tenderness and restriction of movements reduced as a result. These results shows that Kuthikaal Vatham can be successfully managed through Uloga Suttigai and Pattikattal with Kunthriga thailam
Rauwolfia serpentina in P-Glycoprotein Inhibition of Cancer & Diabetes - A Computational Study
Get PDFBackground: The efficient treatment of cancer and diabetes is often constrained by reduced permeation of chemotherapeutic and antidiabetic medications due to p-glycoprotein-mediated efflux, impeding their therapeutic potential and necessitating higher doses or prolonged treatments, which can lead to increased toxicity and financial burden. Ayurveda, an ancient holistic healthcare system, advocates the use of herbal remedies for various ailments. Objective: This study aims to explore the potential of Rauwolfia serpentina and other selected antidiabetic and anticancer medicinal herbs as inhibitor of p-glycoprotein. Materials and Methods: Druggability and pharmacokinetic profile of 185 herbal constituents were evaluated and their binding affinity were interpreted against 6C0V structure of p-glycoprotein utilizing molecular docking with CDOCKER program of Discovery Studio. The stability of the docked complex was validated using molecular dynamics simulation for 40 nanoseconds. ChemMine software was employed for clustering p-glycoprotein herbal inhibitors against standard drug verapamil on the basis of physicochemical properties. Results: Docking analyses revealed that deserpidine and ajmalicine from Rauwolfia serpentina exhibited strong favourable binding interactions with p-glycoprotein, along with other herbal compounds viz., hydrastine from Hydrastis canadensis, palmatine from Tinospora cordifolia and hexadecanoic acid 2-hydroxy-1(hydroxymethyl)ethyl ester from Ipomoea aquatica. Conclusion: This study underscores the potential of combining Rauwolfia serpentina and other medicinal herbs with allopathic drugs to augment their bioavailability and efficacy, providing a novel avenue for advancing therapeutic strategies in oncology and diabetes management. Further experimental validation is necessary to confirm the clinical relevance of these findings
An observational study of Consideration of Anguli Pramana in view of the Health Status in the present era
Get PDFIntroduction: Anguli pramana is an age-old technique of human body measurements stated in Ayurveda. Acharyas have mentioned Anguli pramana for various parts of the body. The study aimed at its validation in the present era on the basis of health status. There are so many factors related to the health status of individual. Hence, the present study aimed at health status wise consideration of Anguli pramana. Method: With prior ethical permission, 770 healthy participants of both gender between age group 18-50 years in Ahmednagar and Nashik region were selected. Measurements were taken for selected body parts. The middle finger width of the right hand at proximal interphalangeal joint was used as a unit for Anguli pramana. Collected data analyzed using the student’s t test for inference. Result: On comparison of measured values for selected parameters and the standard values stated by acharya in both genders found statistically different except for few parameters i.e., Pad parinah, Pad vistar and Prakoshṭha ayam. Discussion: The study shows variations in values obtained by Anguli pramana. This could be due to evolutionary changes and lifestyle of a human being. Though the findings are applicable to the selected sample size and selected parameters, the study could further be extended as this is a non-invasive ancient method of anthropometry. Revision of all the values for the present era will definitely serve as an alternative method for prediction of health of human being
Anti-asthmatic activity of Siddha polyherbal formulation Thoothuvalai Nei
Get PDFBackground: Siddha medicine is a traditional Indian system of medicine which provides a comprehensive treatment for different kinds of diseases among which are respiratory problems. The Siddha system of medicine uses different types of herbals, minerals and therapeutic methods to handle respiratory ailments like wheezing, coughing and shortness of breath. Thoothuvalai Nei is a siddha polyherbal formulation with a traditional use in respiratory health. Objectives: This paper discusses the anti-asthmatic activity of Thoothuvalai Nei by means of pre-clinical experimentation. Materials and Methods: The study was carried out by giving Thoothuvalai Nei to Guinea pigs to find out if it had bronchodilator effect against histamine induced bronchospasm. Results: The research proved that after the treatment the Pre-convulsive Time (PCT) was much longer and thus the formulation appeared to be of great help in bronchospasm relief. The dose dependent reaction proved the therapeutic efficacy of the medicine, with the higher doses showing a greater protection. Conclusion: The above mentioned facts confirm the pharmacological value of Thoothuvalai Nei and it is better to include it as evidence based respiratory care in the healthcare practice. Thus, it is a way to connect traditional knowledge of siddha medicine with the latest and the best scientific knowledge of medical science
Assessing the therapeutic potential of Banana blossom extract in ameliorating Mifepristone-Induced Polycystic Ovarian Syndrome in Rat Model
Get PDFBackground: Polycystic ovarian syndrome (PCOS) is a syndrome defined by ovarian dysfunction which is marked primarily by elevated hormone levels and the presence of polycystic ovaries discovered on ultrasonography. Polycystic ovarian syndrome is an extremely prevalent lifestyle disorder that affects 6 out of 10 women. The management of polycystic ovarian syndrome is largely unclear. This study examines the possible use of Banana Blossom an herbal therapy in a rat model of polycystic ovarian syndrome caused by the medication mifepristone. Methods: For 13 days, female Wistar rats were given 20mg/kg b.w. of mifepristone daily to induce PCOS, which was verified by the sustained estrous cycle. The rats received treatment with Banana Blossom extract orally for 21 days at a dosage of 200, 400 and 800mg/kg b.w. after PCOS induction and standard treatment was metformin. Physical, biochemical parameter and oxidative stress marker was carried out using standard procedure. Result: The PCOS rats reported a significant decline (P˂0.001) in uterine weight, HDL, SOD as well as GSH levels along with a significant rise (P˂0.001) in body weight, periovarian fat, LDL, triglycerides, MDA and glucose level. Banana Blossom extract reversed these effects, with the 800mg/kg b.w. dose providing the most significant improvements in oxidative stress markers and biochemical parameters. Conclusion: After analysing the data, one can conclude that the banana blossom ethanolic extract exhibited an improved therapeutic effect on mifepristone induced polycystic ovarian syndrome in female Wistar rats
A single-arm pilot study to analyse the hepatic safety of Samshamani Vati / Guduchi Ghana Vati (Tinospora cordifolia (Willd.) Miers) for the Prevention of COVID-19
Get PDFBackground - The distribution of Samshamani Vati / Guduchi Ghana Vati (A preparation of Tinospora cordifolia (Willd.) Miers) to a large population as a prophylaxis medicine for COVID-19 was carried out by the Ministry of AYUSH. This drive was based on the promising clinical outcome in asymptomatic cases of COVID-19 infections. A small report has recently confused the public by showing an association between Guduchi (Tinospora cordifolia (Willd.) Miers) use and the development of herb-induced liver injury (HILI) with autoimmune features in some patients. There is no hepatic safety literature to clear up the confusion. Therefore, in the present pilot study, an attempt was made to create a primary database on the hepatic safety of Samshamani Vati / Guduchi Ghana Vati (Tinospora cordifolia (Willd.) Miers). Objectives- To create a primary database on the hepatic safety of Samshamani Vati / Guduchi Ghana Vati (Tinospora cordifolia (Willd.) Miers). Materials and Methods – Samshamani Vati was administered to subjects selected from the OPD of JSS Ayurveda Medical College, Mysuru, by pre-set inclusion and exclusion criteria, in the dose of four tablets in two divided doses after food with lukewarm water for one month for the assessment of hepatic safety clinically and bio-chemically. Study design – The study design was a single-arm, open-prospective, interventional study. Result- Fifty patients were approached for inclusion in the study. Thirty-one healthy persons fulfilled the criteria, and thirty subjects completed the study. The maximum number of studied participants were females between the age of 20 to 30 years. There is no significant change in liver function test (SGOT, SGPT, Alkaline Phosphatase), complete blood count (Hb% and PLT count) and Serum Creatinine before and after one-month of administration of Samshamani Vati. Conclusion- Samshamani Vati / Guduchi Ghana Vati (TC) has not induced any hepatic dysfunction in terms of clinical symptoms or abnormal liver function tests and is relatively safe
Ayurvedic Management of a Third Degree Burn Wound in a Patient with Diabetes Mellitus - A Case Report
Get PDFBurn injuries are the most agonizing, excruciating type of injuries causing disfigurement and disability in the victims. Such injuries need proper wound management care, and if the victim is diabetic the management and wound healing tends to get difficult and susceptible to infections. In Third degree burns the affected area is charred, parchment like, painless and insensitive, with thrombosis of superficial vessels. It requires grafting. A 60 year old female patient, known case of Diabetes Mellitus with large approximately 25%TBSA (Total Body Surface Area) burn wound sought Ayurvedic treatment. A non-healing wound can cause severe complications if left untreated, and it was recommended by her surgeon to undergo a skin grafting surgery. However, the patient was unwilling for it given her diabetic condition. The patient was treated with internal and external Ayurvedic medicines where significant wound healing was achieved in a span of 90 days. Treatment was aimed for Shodhana (Cleansing) and Ropana (Healing) of the wound and amelioration of vitiated Doshas (morbific diathesis) keeping in consideration the Prameha (Diabetic condition) of the patient. The study proves the efficacy of Ayurvedic treatment in managing a chronic non-healing, third degree burn wound in a diabetic patient without any complications. It infers that the Burn injuries can be treated with Ayurveda within the expected time period of wound healing
An Ayurvedic management of post covid lung fibrosis: A case study
Get PDFSARS- COVID has been forged to most significant pandemics in recent history. There is a swift gathering of information regarding its epidemiological, clinical progression, diagnostic assessment, treatment and its complications. One of the primary concerns following recovery from the pandemic is post-COVID-19 pulmonary fibrosis. The risk factors contributing to the development of fibrotic-like radiographic abnormalities following severe COVID-19 are not yet fully understood. Such Fibrotic changes can be linked to symptoms and physical functioning. A 42-year-old female patient came at Dr. Sevak’s OPD in June 2023. Patient had symptoms of persistent dry cough, irritation in throat, chest congestion and loss of appetite appeared after the SARS COVID infection and were gradually increased. The patient was diagnosed with lung fibrosis following a clinical examination and by investigation like chest radiology. The patient was successfully treated with medications like Sameer pannag rasa, yashtimadhu churn, hingvashtak churn, Eladi vati, haridra- manjistha- pippali churn, Talisadi churn and Agasti haritaki rasayan (avleha). Medications were chosen appropriately at each follow-up according to condition and recovered completely