International Journal of Ayurvedic Medicine
Not a member yet
1492 research outputs found
Sort by
Potential implications of Ayurvedic treatment along with Marma chikitsa and Indian classical music therapy in Ardhavabhedak i.e (Migraine without aura)
Full text linkThe brain is the most complex organ of the human body. It is the crown jewel of the body as it performs various essential functions. Globally, headache disorders affect approximately 40% of the population, nearly 3.1 billion people in 2021(1). It is more common in females as compared to males. Headache disorders ranked third (after stroke and dementia) in accounting for overall neurological disease burden as measured by age-standardized disability-adjusted life years (DALYs) in 2019. It comes with a constellation of things that it impacts person’s activities of daily living and affect their ability to do things that they love the most. Migraine without aura is a recurrent and debilitating disorder having pulsatile, unilateral moderate to severe headache lasting from 2-72 hours. Associated symptoms include nausea, vomiting, photosensitivity and phonosensitivity. In Ayurveda it is correlated with one of the Shirorogas i.e Ardhavabhedak. According to Acharya Charaka it is Vata-Kaphaja and according to Acharya Sushrut it is Tridoshaja vyadhi. In this case study, a male patient of middle age suffering from chronic severe migraine was treated with the Ayurveda medications and panchakarma resulting in significant relief. An additional Marma chikitsa and Indian classical music i.e Raga Mohanam therapy was also given. The integrative treatment modality has shown significant relief in reducing the episodes and intensity of pain of Migraine (Ardhavabhedak)
Ayurvedic management of Klaibya (Impotency) – A case study
Full text linkImpotency means a man who is unable to perform sexual intercourse, being powerless and unable to carry out sexual activities. Nowadays Klaibya is considered as one of the most common problems affecting the males having variable severity. Change in lifestyle, food habits, sedentary lifestyle and some psychological causes like Chinta, Shoka, Bhaya, Krodha etc. causes Klaibya. The male sexual dysfunctions have been elaborately described as Klaibya (Impotency) in Ayurvedic classics. In clinical practices Klaibya (Impotency) is the most common psychosexual disorders. It has a significant negative impact on the quality of life of the patients along with their partners. It is projected as a medico-social problem. Vajikarana, a specialized branch of Ayurveda deals in treating these problems. It refers to a problem during any phase of the sexual cycle that restricts the man from experiencing satisfaction from the activity. Nowadays the incidence of sexual dysfunction is increasing due to age, sedentary life style, unhealthy foods etc. About 5% of 35 years old men and between 15% and 25% of 50 years old men experience sexual dysfunctions. Vajikarana (Medicine which improves sexual capability) branch of Ashtanga Ayurveda (one of the subjects of Ayurved study) deals with fertility, potency and healthy progeny. In this branch diagnosis and management of infertility and Sexual dysfunction are dealt in detail
Observations of Mahakumbh
Full text linkThe article "Observations of Mahakumbh" by Ashwini Kumar Rai provides a detailed narrative of the Kumbh Mela experience in Prayagraj, as observed in January 2025. The writer begins by describing the evolving setup of the Kumbh city, the construction of sectors, and the dedication of pilgrims and organizations preparing for the grand spiritual event. Special attention is given to the atmosphere in Sector 10, where the sounds of bhajans and religious activity reverberate through the air. As the preparations unfold, the author reflects on changes in terminology, such as replacing the term \u27Shahi\u27 with \u27Amrit\u27 to restore ancient traditions. Throughout the article, the importance of humility, devotion, and selfless service is emphasized, particularly through encounters with sadhus and monks, such as the elderly monk carrying a heavy tree trunk. The story conveys profound insights on perseverance, spirituality, and the meaningfulness of life. The observations highlight the harmony between administrative efforts and the spiritual essence of Kumbh, noting that despite challenges, the event\u27s spiritual energy remains potent. The narrative concludes with reflections on assumptions, administrative skills, and the necessity of experiencing the Kumbh without prejudices to truly appreciate its significance
Efficacy of Brahmighruta in Mild Neurocognitive Disorder - A Randomized Controlled Trial
Full text linkContext: Mild Neurocognitive Disorder (NCD) due to possible Alzheimer’s disease (AD) is the most common cause and lacks adequate management strategies. Aims: Current study aims to evaluate the efficacy of Brahmighruta (Ayurveda Medicine) on Mild Neurocognitive Disorder due to possible Alzheimer’s disease. Settings and Design: Study was a randomized controlled parallel group trial. Methods and Material: Total 52 patients meeting the DSM V criteria of mild NCD due to possible AD, above 60 years of age, either sex participated in the study. They were randomly divided into two groups, Group I received donepezil 10 mg once a day for 90 days and group II received Brahmighruta 10ml twice a day before food with warm water for 90 days. Assessments were through Mini mental state examination (MMSE), Alzheimer’s disease Assessment Scale-Cognitive subscale (ADAS-Cog), Disability Assessment for Dementia (DAD), Cornell Scale for Depression in Dementia (CSDD), DEMQOL (version 4) and UKU Side effect scale. Assessments were on every 15th day. Results: Effect of Brahmighruta and donepezil were comparable in MMSE (p=0.67), ADAS Cog (p=0.16), DAD (p=0.07), CSDD (p=0.29), DEMQol (p=0.14). Effect size was large. Improvements were observed in both the groups on within group assessments. Eight mild adverse events were noted with Donapezil but non with Brahmighruta. Conclusions: Brahmighruta and Donapezil showed similar improvements in all outcome measures. Due to lack of adverse effects Brahmighruta may be a preferred substitute for Donapezil. Needs further studies
Enhancing Ayurvedic Diagnostics: Correlation and Validation of Sensor-Based Prakriti Parikshan through Comprehensive Questionnaire Analysis
Full text linkThe field of Ayurvedic engineering seeks to modernize traditional Ayurvedic practices using contemporary technological methods. This research paper introduces an innovative method for Ayurvedic Prakriti Parikshan, the evaluation of individual constitutions using sensor-based Nadi Pariksha and validating it using analysis of questionnaire responses.
The proposed method includes the use of an extensive questionnaire consisting of 75 questions, validated by Ayurvedic experts, in conjunction with sensor-based pulse readings to identify Vata, Pitta, and Kapha doshas. Techniques such as Baseline wander removal filters for preprocessing, feature extraction using the 1-dimensional discrete wavelet transform (1D DWT) and Fast Fourier Transform (FFT). The gathered data is consolidated and analyzed to determine the predominant dosha in each person. Later the doshas obtained from sensor-data are validated using the doshas obtained from the questionnaire-data demonstrating an accuracy rate of 95%
Comparative anti-inflammatory potential of ingredients of Purandara Vati and Shwasakuthar Rasa: A preclinical evidence based portrayal
Full text linkAsthma is a multifaceted, long-term inflammatory disease linked to tissue remodelling of the airway structure and hyper-responsiveness of the airways. The goal is to get the best asthma control possible while using the least amount of medication. It has been reported that oral consumption of corticosteroids increases the chances of osteoporosis, bone fractures, cataracts, pneumonia, opportunistic lung infections, diabetes, and obesity in those with asthma. Inhaled corticosteroids have also been linked to an increased risk of cataract development, respiratory infections, and BMD loss in asthmatic patients. Aspirin and NSAIDs have enormous side effects, such as hyperacidity and gastrointestinal disturbances, so long-term use of these medications is not recommended. Therefore, medications with few adverse effects and strong anti-inflammatory and asthmatic effects are needed to treat inflammatory disease. Shwasakuthara rasa and Purandara Vati are two well-known formulations for management of asthma with quite similar ingredients and can be therapeutically implemented as anti-inflammatory formulation. This article delineates preclinical evidences for anti-inflammatory potential Shwaskuthara rasa and Purandara Vati
A single-arm clinical study to evaluate the efficacy of Chirbilva Ghana Vati in the management of Hyperlipidaemia
Full text linkHyperlipidaemia, characterized by elevated blood lipid levels, is a major cause of coronary heart disease and atherosclerosis. In India, dyslipidaemia affects 25-30% of urban and 15-20% of rural populations, with familial hypercholesterolemia prevalent in 1:125 to 1:450 individuals in urban areas. In Ayurveda, hyperlipidaemia is linked to conditions like Rasagata Sneha Vriddhi (increase in fat in the circulation), Rasa Raktagata Sneha Vriddhi (increase in fat in the blood), and Medovriddhi (increase in fat tissue), attributed to sedentary lifestyles and Kapha-aggravating diets. This leads to excess Medas (fat) that block nutrient channels, a condition similar to modern hyperlipidaemia. Objective: The study aimed to reduce lipid accumulation through Rukshana Chikitsa (drying therapy). Chirbilva, known for its Ruksha (dry) and Laghu (light) properties and Kapha-Medohara (fat-reducing) action, was selected for managing Kapha-dominant lipid disorders such as hyperlipidaemia. Material and methods: The study, conducted at Dr. D.Y. Patil College of Ayurveda and Research Centre, Pune, the study included 30 patients with hyperlipidaemia. Chirbilva Ghana Vati was administered as per classical Ayurvedic guidelines. Lipid profile scores were evaluated pre- and post-treatment using criteria based on the American Journal of Lifestyle Medicine, with statistical analysis set at p < 0.05. Result: Chirbilva Ghana Vati showed significant reductions in serum cholesterol and LDL levels, indicating moderate efficacy. However, changes in HDL and triglyceride levels were not statistically significant. Conclusion: Chirbilva Ghana Vati demonstrates moderate effectiveness in managing hyperlipidaemia. For enhanced and sustained results, longer treatment duration along with appropriate dietary and lifestyle modifications is recommended
In-Vivo and In-silico Study of Ludwigia perennis L. Leaf Extract: A Promising Source of Anti-depressant Agents
Full text linkLudwigia perennis is used in India to treat several ailments in the traditional system of medicine. The chloroform leaf extract of Ludwigia perennis was evaluated for depression and anxiety using in vivo and in silico studies. Wistar albino rats were divided into groups based on parameters like control, standard, 20, and 30 mg/kg b.w. chloroform leaf extract groups for drug administration using gastric intubation. The tail suspension test (TST) and forced swim test (FST) were used to assess the antidepressant activity. Molecular docking against monoamine oxidase A (MAO-A), ADME analysis, toxicity tests, and pass prediction studies were among the in silico investigations. A delayed onset of immobility and lowered immobility time were seen at both the treatment doses (FST: 38.49±2.04 and 35.55±2.95 s; TST: 30.23±1.73 and 26.72±2.26 s) and the standard drug fluoxetine (FST: 31.26±1.76 and TST: 25.54±1.08 s), indicative of its antidepressant ability. While 30 identified phytochemicals were docked with monoamine oxidase A proteins, six compounds mainly showed higher binding affinity. It is stated that γ-sitosterol has a binding affinity of -8.5. The binding affinity of five compounds, namely stigmasterol, ergosterol, dibutyl phthalate, campesterol, 7,9-Di-tert-butyl-1-oxaspiro(4,5)deca-6,9-diene-2,8-dione is -8.2, -8.2, -8.0, -7.8, and -7.4 are like this. The results of the molecular docking studies indicate that the six chemicals that were successfully docked have an anti-depressive impact. Apart from docking, pharmacokinetic and PASS tests validated their drug-likeness, predicted safety after consumption, and predicted pharmacological effects. The chloroform leaf extract of Ludwigia perennis is a rich source of bioactive compounds with strong antidepressant properties
Effect of Madhuka taila nasya with and without Japaakusuma lepa in akaalapalitya – A comparative clinical study
Full text linkIntroduction: Healthy hair is a sign of beauty and wellbeing. The appearance of a person is significantly altered by hair colour. Hair greying is a visible sign of ageing. Premature greying has negative effects on the appearance, self-confidence, self-esteem, and social acceptance of the affected individual. Akaalapalitya is a burning problem faced by youth today worldwide. Acharya Charaka has mentioned Nasya followed by Lepa application is the best treatment for Akaalapalitya. This study was designed to compare the effect of Madhuka taila nasya over Madhuka taila nasya and Japaakusuma lepa in Akaalapalitya. Aim: To study the effect of Madhuka taila nasya in the management of Akaalapalitya. To study the effect of Madhuka taila nasya and Japaakusuma lepa in the management of Akaalapalitya. To compare the efficacy of Madhuka taila nasya with and without Japaakusuma lepa in the management of Akaalapalitya. Materials and Methods: A randomised controlled trial was conducted with 40 patients of Akaalapalitya selected from O.P.D and I.P.D of K.A.M.C after fulfilling the inclusion and exclusion criteria. Participants were divided in to two equal groups. Group A received Madhuka taila nasya in ashtabindu pramana for 7 days. Group B received Madhuka taila nasya in ashtabindu pramana for 7 days followed by Japaakusuma lepa for 7 days. Baseline and post treatment evaluation was done on day 0 and day 8 for group A. It was done on day 0 and day 15 for group B. Both the groups were compared at follow up on day 21.Results: Comparative analysis of the overall effect of the treatment in both the groups was done statistically with unpaired t test. The test shows that the treatment is significant in Group B with overall result of 88.54%. Conclusion: Madhuka taila nasya with Japaakusuma lepa showed significant efficacy over Madhuka taila nasya alone in management of Akaalapalitya.
Acne Treatment Practices and Patient Preferences for Herbal Products: A Conjoint Analysis
Full text linkThis study aims to understand the acne treatment practices and patient preferences, focusing on herbal products and identifying the most and least preferred attributes using conjoint analysis. Five key attributes were evaluated: product form (cream, lotion, gel), expected treatment time (1 week, 2 weeks, 4 weeks), packaging (tube, jar), type of medication (over the counter or prescription), and price (economy, mid-priced, premium). A survey was conducted with 408 respondents using purposive, snowball, and availability sampling methods. Data were analysed using SPSS software through conjoint analysis to determine the cardinal utility of each attribute. Results showed that 50% of respondents used medication for acne, while others relied on home remedies or lifestyle changes. Only 20% reported using herbal products. Among those using acne medication, 46.6% observed noticeable results within one week, and most reported no side effects. While 40% of participants were satisfied with their current treatments, 34.3% expressed dissatisfaction. About 34% of patients preferred herbal acne treatments, showing a liking for products that are applied once daily, white in colour, fragrant, and dispensed in fingertip quantity. The most significant attribute influencing patient preference was treatment time, followed by product form, price, packaging, and medication type. Patients preferred herbal gels that are over the counter, low cost, packaged in jars, and deliver results within a week. These findings provide valuable insights into consumer expectations and can aid in the development of effective, patient friendly herbal acne treatments that align with real world preferences