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The Effect of Anthocyanin-Rich Purple Corn Extract on the Healthspan of Caenorhabditis elegans
Get PDFIf aging is a result of the degradation of the proteostasis network (PN), then treatments that support proteostasis are expected to increase lifespan. Anthocyanins have been credited with the capacity to modulate cognitive and motor function, enhance memory and having a role in preventing age-related declines in neural function. We are studying the effect of standardized purple corn extract on a transgenic strain of model organism C. elegans. We expect to see a positive effect on healthspan, resistance to oxidative stress, and mortality rate. Analysis of the composition of purple corn extract in comparison with other natural extracts shown to have longevity effects will be presented. If this natural product is shown to increase healthspan in our study, this could lead to a breakthrough for promoting healthy aging in humans in a cost effective way
The Effect of Creatine on 24-Hour Blood Pressure, Mean Arterial Pressure, and Pulse Pressure
Get PDFPURPOSE: The purpose of the study was to investigate the effect of a 1 week creatine supplementation (CrS) on blood pressure (BP), mean arterial pressure (MAP), and pulse pressure (PP) in healthy males and females. METHODS: Subjects were 10 males (21±1.2 year) and 4 females (20.3 ± 0.47 year), with VO2max values of 53.53 ± 4.6 ml/kg/min (males) and 47.7 ± 2.9 ml/kg/min (females). Subjects were divided into two groups: placebo supplementation (PS) and CrS. Subjects attended a pre-supplementation and post-supplementation exercise intervention where subjects ran for 30 min at 70-80% of VO2max. Between the exercise interventions, subjects consumed 0.3 g/kg of body weight/day of supplement for 7 days. Following each exercise intervention, subjects wore an ambulatory blood pressure monitor (ABPM) for 24 hr to collect BP, MAP, and PP. RESULTS: A 7 day CrS will result in benefits to cardiovascular health (CVH). The CrS group will have lower mean BP, MAP, and PP when compared to the PS group following the second exercise intervention. CONCLUSIONS: The proposed research will contribute to greater understanding of the effects of CrS on CVH
Hydrometeorological Characteristics of Ice Jams on the Pemigewasset River in Central New Hampshire
No full textIce jams regularly occur across the Northeast U.S. during the winter and early spring and can result in significant localized flooding, such as those that occurred on the Pemigewasset River in Plymouth, NH on 26 February 2017 and 13 January 2018. The hydrometeorological characteristics of 20 ice jams that occurred on the Pemigewasset River in Plymouth, NH since 1981 are investigated. Composite analyses indicate a period of slightly below normal temperatures over the Northeast U.S. from 1–2 weeks before the ice jam date that transitioned into a period of highly anomalous temperatures \u3e7˚C above normal from two days before through one day after the ice jam date. All 20 events were associated with a period of enhanced integrated vapor transport (IVT) \u3e250 kg m–1s–1during the anomalously warm period. The composite synoptic-scale flow over eastern North America was characterized by a plume of integrated water vapor values \u3e25 mm and IVT magnitudes \u3e600 kg m–1s–1into New England resulting in average precipitation totals of 30–50 in the Pemigewasset watershed
Therapy Pets on Campus: Reducing Stress, Homesickness, and Loneliness
Get PDFYou have seen them on campus. Bright eyes, welcoming faces, green vests, and wagging tails! Since 2013, we have been scheduling formal pet therapy interactions on campus in academic building, residence halls, community buildings, and on the Mary Lyon lawn. Our certified pet therapy teams have been invited to specific classrooms and to campus-wide events. Throughout the years, these teams have helped countless students, faculty, and staff relief stress, reduce anxiety, and to make connections with others engaging with the teams. This panel discussion will present the science behind why pet therapy programs have strong impacts on the college-age population, discuss the training and requirements necessary to become a nationally certified therapy team, and share the personal experiences of a faculty member who designed a course around human-animal interactions
Supporting Student Employee Growth Through the Habits of Mind
No full textJess & Steven will be providing an overview on effective “Student Worker Trainings” along with a special focus on “Performance Evaluations and reviews”. This session is designed to be a conversational experience where active discussions, and questions are encouraged
Degree Works: Questions, Tips, and Tricks
No full textIf you’re new to Degree Works, or have questions – please join us! The Registrar’s Office will do an introduction on Degree Works and how to access it. We’ll go over the benefits of using Degree Works with your advisees and how to ‘read’ the audit and the legend, the block structure, as well as how it differs from the transcript. We’ll show the What-If feature for students considering changing their major or catalog year. We’ll discuss exceptions – what they are and how you’ll see them displayed. We’ll review the curriculum/catalog cycle and when Degree Works is updated with new requirements as well as blanket agreements that have been approved. We will leave time for other questions or scenarios you might have
Exploring How New Hampshire Non-Profit Organizations Can Better Serve Women of Color
No full textThere are many gaps in the research concerning how well non-profits are adequately serving the specific needs and problems of women of color. I examined the literature that currently exists discussing various issues in the United States that disproportionately affect women of color. Among the issues that I am including in the scope of my research are the following: mass incarceration, poverty, and violence. I also explored existing research pertaining to empowerment processes to understand how non-profit organizations can and should be treating women of color. My research project will focus solely on New Hampshire non-profit organizations that address mass incarceration, poverty, and/or violence. To understand the extent in which these organizations are serving women of color, I will be surveying, as well as interviewing, employees that manage these non-profit organizations. From the data I collect, I will then determine how New Hampshire non-profit organizations can better serve women of color
Effects of Elderberry Extract on the Insulin/ IGF-1 (IIS) Pathway of Caenorhabditis elegans
No full textProteostasis is an essential aspect of protein regulation, and the inability to maintain the proteome can lead to many neurodegenerative diseases. Caenorhabditis elegans, CL4176 is a transgenic strain designed to produce β-amyloid42 (Aβ), disrupt proteostasis, and provide insight into age-related diseases. Treatments with elderberry (S. nigra) extract (EBE) results in a decrease in Aβ toxicity and extension of life span. To explore the involvement of the insulin/ IGF-1 (IIS) metabolic pathway, we knocked down the age-1, daf-2, daf-16, and hsf-1 genes. We then confirmed knock downs with RT-PCR, and found that EBE affects lifespan expansion primarily by hsf-1. These results are used to confirm that EBE extends lifespan through the IIS pathway, and will contribute to further study on potential benefits in humans