Repositorio institucional - Concytec
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LA Referencia, el rol de los sistemas CRIS en el ecosistema de ciencia abierta regional
No full textPresenta a LA Referencia mencionando a los Organismos que conforman el Consejo Directivo, el modelo de agregación, sus alianzas y perpectivas en torno a un Ecosistema Regional de Ciencia Abierta. Asimismo, muestra los principales avances los sistemas CRIS nacionales
De la interoperabilidad a la Visión 360º de la labor de nuestros investigadores
No full textExpone los avances y perpectivas del Portal de Investigación CRIS de la Universidad del Pacífico denominado “FacultyUP”
Guía que establece la equivalencia entre la teoría de cambio y el árbol de problemas y objetivos: la teoría de cambio para el diseño y evaluación de instrumentos financieros de CTI
No full textPresenta el tercero de una serie de documentos que son parte del modelo de evaluación de impacto de instrumentos financieros de CTI (Ciencia, Tecnología e Innovación), el cual realiza el análisis y desarrollo de la equivalencia entre la teoría de cambio y el árbol de problemas y objetivos como parte del diseño de las evaluaciones de impacto de instrumentos financieros en CTI (IF-CTI)
Guidelines for correlation coefficient threshold settings in metabolite correlation networks exemplified on a potato association panel
No full textBackground
Correlation network analysis has become an integral tool to study metabolite datasets. Networks are constructed by omitting correlations between metabolites based on two thresholds—namely the r and the associated p-values. While p-value threshold settings follow the rules of multiple hypotheses testing correction, guidelines for r-value threshold settings have not been defined.
Results
Here, we introduce a method that allows determining the r-value threshold based on an iterative approach, where different networks are constructed and their network topology is monitored. Once the network topology changes significantly, the threshold is set to the corresponding correlation coefficient value. The approach was exemplified on: (i) a metabolite and morphological trait dataset from a potato association panel, which was grown under normal irrigation and water recovery conditions; and validated (ii) on a metabolite dataset of hearts of fed and fasted mice. For the potato normal irrigation correlation network a threshold of Pearson’s |r|≥ 0.23 was suggested, while for the water recovery correlation network a threshold of Pearson’s |r|≥ 0.41 was estimated. For both mice networks the threshold was calculated with Pearson’s |r|≥ 0.84.
Conclusions
Our analysis corrected the previously stated Pearson’s correlation coefficient threshold from 0.4 to 0.41 in the water recovery network and from 0.4 to 0.23 for the normal irrigation network. Furthermore, the proposed method suggested a correlation threshold of 0.84 for both mice networks rather than a threshold of 0.7 as applied earlier. We demonstrate that the proposed approach is a valuable tool for constructing biological meaningful networks.Consejo Nacional de Ciencia, Tecnología e Innovación Tecnológica - Concyte
Plasmodium falciparum outbreak in native communities of Condorcanqui, Amazonas, Perú
No full textBackground: Malaria remains a serious health threat in the Amazonas Region of Peru and approximately 95% of the cases, mainly Plasmodium vivax, are found in native communities of The Rio Santiago District, Condorcanqui Province. In 2019, more than one thousand malaria cases were reported, with an unusual number of Plasmodium falciparum autochthonous cases. The present study aims to report this P. falciparum outbreak while describing the epidemiology of malaria and the risk factors associated in the native communities of Amazonas, Peru. Methods: The DIRESA-Amazonas in collaboration with the Condorcanqui Health Network and the Institute of Tropical Diseases of the UNTRM carried out a malaria Active Case Detection (ACD III) between January 31st and February 10th of 2020. A total of 2718 (47.4%) individuals from 21 native communities grouped in eight sanitary districts, were screened for malaria infections. Each participant was screened for malaria using microscopy. Follow-up surveys were conducted for all malaria positive individuals to collect socio-demographic data. Spatial clustering of infection risk was calculated using a generalized linear model (GLM). Analysis of risk considered factors such as gender, age, type of infection, symptomatology, and parasitaemia. Results: The study suggests that the P. falciparum index case was imported from Loreto and later spread to other communities of Rio Santiago during 2019. The ACD III reported 220 (8.1%) malaria cases, 46 P. falciparum, 168 P. vivax and 6 mixed infections. SaTScan analysis detected a cluster of high infection risk in Middle Rio Santiago and a particular high P. falciparum infection risk cluster in Upper Rio Santiago. Interestingly, the evaluation of different risk factors showed significant associations between low parasitaemia and P. falciparum asymptomatic cases. Conclusion: This is the first report of a P. falciparum outbreak in native communities of Condorcanqui, Amazonas. Timely identification and treatment of symptomatic and asymptomatic cases are critical to achieve malaria control and possible elimination in this area. However, the current malaria situation in Condorcanqui is uncertain, given that malaria ACD activities have been postponed due to COVID-19. © 2021, The Author(s).Consejo Nacional de Ciencia, Tecnología e Innovación Tecnológica - Concyte
Recomendaciones técnicas para la correcta agregaciónde los repositorios en ALICIA y LA Referencia
Full text linkBrinda recomendaciones técnicas con el fin de que los repositorios puedan lograr una correcta agregación tanto al Repositorio Nacional ALICIA como a LA Referencia
Computational and experimental analysis of a Glaucoma flat drainage device
No full textThe authors would like to thank to FONDECYT-UK J008-2016 for the financial support during the course of this work.This paper presents a computational and experimental analysis of a glaucoma flat drainage device (FDD). The FDD consists of a metallic microplate placed into the eye sclerocorneal limbus, which creates a virtual path between the anterior chamber and its exterior, allowing the intraocular pressure (LOP) to be kept in a normal range. It also uses the surrounding tissue as a flow regulator in order to provide close values of LOP for a wide range of aqueous humor (AH) flow rates. The Neo Hookean hyperelastic model is used for the solid part, while the Reynolds thin film fluid model is used for the fluid part. On the other hand, a gravitational-driven flow test is implemented in order to validate the simulation process. An in vitro experiment evaluated the flow characteristics of the device implanted in fourteen extirpated pig eyes, giving as a result the best-fit for the Young modulus of the tissue surrounding the device. Finally, according to the resulting computational model, for a range of 1.4-3.1 mu L/min, the device presents a pressure variation range of 6-7.5 mmHg. (C) 2021 Published by Elsevier Ltd.Consejo Nacional de Ciencia, Tecnología e Innovación Tecnológica - Concyte
Monumental Inca remains and past seismic disasters: A relational database to support archaeoseismological investigations and cultural heritage preservation in the Andes
No full textAs recent dramatic and numerous examples demonstrate, earthquakes still constitute a significant threat to cultural heritage (Bam 2003; L'Aquila 2009; Haiti 2010; Nepal 2015). By damaging the historical legacy, telluric phenomena affect economic and touristic incomes and alter regional identities and collective psyche. In the Andes, as in other emerging regions across the globe, deficient seismic hazard assessments, constant lack of resources, and inadequate maintenance programs are additional challenges for cultural heritage management. As part of our archaeoseismological investigation in the Cusco area (Peru), we developed a relational database, which seeks to identify, record and inventory seismic damage in pre-Columbian architecture. This work presents the main characteristics of the structure and design of the RISC (Risque sismique, Incas et Socie ' te ' a` Cusco) database and its contribution in supporting the fieldwork organization and facilitating the data acquisition. The collected architectonical evidence constitutes the first large archaeoseismological dataset in South America and will provide valuable complementary data in Peru to regional seismic hazard studies. We here aim to demon-strate that an ergonomic and user-friendly interface has a role to play in supervising and preserving the cultural heritage in active seismic areas. By converting ad-hoc surveys into routine inspections, RISC could become an effective low-tech monitoring system, providing relevant support for disaster risk reduction plans in archaeo-logical sites conservation. We stress the necessity of adopting cost-effective and easy-to-implement tools for cultural heritage monitoring in emerging countries through this case study. Our database may represent a relevant methodological background and template for further initiatives in both fields of archaeoseismology and cultural heritage protection.This work would not have been possible without the cooperation of the Decentralized Department of the Ministry of Culture from Cusco and the Geopark of Machu Picchu. We also thank Leo Marconato, Lorena Rosell, Peter Molnar, Sara Neustadt, Fabrizio Delgado and Xavier Robert for their precious assistance during the field campaigns. The authors would like to express their gratitude to H ' el`ene Dessales for her enthusiasm in sharing her feedbacks on the ACoR database as well as to Philippe Garnier for his constructive proofreading. This work was part of the CuscoPATA project (006-2016-FONDECYT) and of the interinstitutional agreement between IRD (Institut de Recherche pour le D ' eveloppement) and INGEMMET (Instituto Geol ' ogico, Minero y Metalurgico del Peru). This work has been realised in the framework of the IDEX CDP [email protected] Alpes as part of the program ``Investissements d'Aveniroverseen by the French National Research Agency (ANR-15-IDEX-02). The project has received, as well, financial support from the CNRS through the MITI interdisciplinary programs and from the IRD
Recent progress in and prospects for supercapacitor materials based on metal oxide or hydroxide/biomass-derived carbon composites
No full textThis work was supported by Peruvian government agencies CONCYTEC and FONDECYT/World Bank (contract 026-2019 FONDECYT-BM-INC.INV) and the Sao Paulo Research Foundation (FAPESP) through the fellowships granted to J. M. G. (FAPESP 2018/16896-7).In the pursuit of high power and energy density electrochemical energy storage technologies, hybrid supercapacitors (HSCs) have drawn increasing research attention due to the combination of the outstanding power density of supercapacitive materials with the high energy density of battery-type materials into a single device. At the same time, many efforts are underway to design effective electrode materials which exhibit good electrical conductivity and abundance, as well as having low cost with easily controllable intrinsic properties. Among various electrode materials, biomass-derived carbon has attracted considerable attention because of the abundance, low cost, environment friendliness and promising electrochemical properties. Furthermore, biomass carbon-based materials in combination with metal oxides/hydroxides with synergetic effects for supercapacitor applications have been a trend in recent years as high-performance electrode materials. Therefore, in this review we focus on the recent progress and current trends in biomass carbon-based composites containing mono-, bi- and trimetallic metal oxides and hydroxides for supercapacitor applications, highlighting the top 5 composites based on mono- and bimetallic oxides and hydroxides. Finally, the prospects and possible future directions are discussed.Consejo Nacional de Ciencia, Tecnología e Innovación Tecnológica - Concyte
A review on the negative impact of different elements during cyanidation of gold and silver from refractory ores and strategies to optimize the leaching process
No full textThis research was supported by the Phosagro/UNESCO/IUPAC Partnership in Green Chemistry for Life (Contract ). JCFRR acknowledges the support of 4500245048FONDECYT and the World Bank (Contract 106-2018).The participation of GL was possible through the Real Life Experience (RLE) program at UTEC. Karinna Visurraga is thanked for administrative support.The ongoing depletion of gold and silver-containing ore deposits demands a shift towards the processing of more complex sources. Leaching of gold or silver from these sources, which are named refractory and are typically low-grade, can be complicated due to one or more of the following effects: (1) kinetic or thermodynamic impediments on cyanide diffusion or on the dissolution of minerals, (2) readsorption of leached gold or silver (preg-robbing), and (3) excessive cyanide consumption due to the presence of cyanicidal agents. This article reviews the occurrence of these effects as a function of the elemental composition and compiles strategies to overcome them. The first type of refractory behavior was found to be related to arsenic or antimony sulfides and sulfosalts, manganese oxides, permanganates, iron sulfides, oxides, and hydroxides, tellurides, as well as different sulfur-containing minerals. In general, most kinetic or thermodynamic impediments are addressed by performing intensive grinding and through oxidation processes for sulfides, such as roasting, pressure oxidation, chemical oxidation or biological oxidation. On the other hand, preg-robbing activity was described as common in ores that contain carbonaceous matter, silicates, and sulfides. Strategies to deal with preg-robbing ores often include the destruction or deactivation of the preg-robbing surface, or the addition of another adsorbent to compete with the preg-robber (carbon-in-leach). Finally, cyanicidal agents include sulfides and compounds containing base metals, mainly copper, iron, zinc, and nickel. In the case of sulfides, performing oxidation processes is common, while base metals often require one or more pre-leaching stages in which they can be partially removed from the ore prior to cyanidation. Even though this review intends to serve as a compendium of strategies directed at improving cyanidation processes depending on the nature of the elements present in a feed, a final discussion stressing the importance of developing ore-specific strategies is given. © 2021 Elsevier LtdConsejo Nacional de Ciencia, Tecnología e Innovación Tecnológica - Concyte