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Assessing the Feasibility of Implementing a Pharmacy- Led Medication Take-Back System in Kerala: A Comparative Analysis of France’s Cyclamed Model
Get PDFImproper disposal of unused and expired medicines poses significant risks to public health and the environment, particularly in areas like Kerala, India, where structured disposal systems are lacking. This research investigates the possibility of introducing a pharmacy-led medication takeback initiative in Kerala, inspired by the CYCLAMED program successfully implemented in France. The study utilized a quantitative methodology, collecting data from pharmacists in diverse settings across Kerala to assess existing disposal habits, awareness levels, practical challenges, and readiness for such a program. Additionally, secondary sources were reviewed to examine the operational strengths and outcomes of the CYCLAMED model. Findings show strong support among pharmacists for a take-back initiative, with 73% willing to participate and over 70% believing their pharmacies have the resources to implement the system. Nonetheless, several challenges were identified, including unclear regulatory frameworks, limited public awareness, inadequate infrastructure, and financial constraints. Rural pharmacies, in particular, reported lower preparedness, emphasizing the need for tailored approaches in these regions. A majority of respondents highlighted the importance of government-led education campaigns, clear regulatory framework, and financial assistance as key enablers of success. Overall, the study concludes that a pharmacy-led take-back system is both practical and needed in Kerala, provided that current gaps are addressed through coordinated policy, regulatory reform, and community engagement. Drawing insights from international practices, the research recommends a comprehensive strategy involving collaboration between healthcare stakeholders, government authorities, and the public. Such a system could play a crucial role in improving pharmaceutical waste management, safeguarding public health, and promoting environmental sustainability in the region
Exploring the Application of AI/ML Systems in Fostering Regulatory Compliance and Audit in Oncology Trials
Get PDFThis study investigates the integration of artificial intelligence (AI) and machine learning (ML) systems in regulatory compliance and audit processes within oncology clinical trials. Through a quantitative survey of 102 clinical research professionals, the research evaluates current adoption patterns, effectiveness, and challenges of AI/ML implementation in compliance monitoring. The findings reveal that while 47.1% of organizations currently use AI/ML tools for compliance, adoption remains fragmented and transitional. Natural Language Processing (19.6%) emerged as the most commonly used technology, primarily for documentation management. AI/ML systems demonstrated moderate effectiveness in detecting protocol deviations (28.4% rating them moderately effective) and reducing data discrepancies (46.1% reporting improvements). Risk assessment (28.4%) and compliance monitoring (28.4%) were identified as the most improved aspects following AI/ML adoption. However, significant barriers persist. Key challenges include data privacy concerns (23.5%), lack of regulatory clarity (21.6%), and technical complexity (20.6%). Only 41.2% of respondents believed their AI/ML tools were adequately validated for regulatory compliance, while 25.5% perceived these systems as lacking transparency.
The study revealed role-based differences in perceptions, with technical professionals expressing greater confidence in AI/ML systems compared to regulatory and quality assurance staff. Despite demonstrable benefits in error reduction (63.7% reported decreased human error) and audit efficiency, only 32.4% of respondents recommended wider adoption. This cautious stance reflects ongoing concerns about validation standards, explainability, and regulatory acceptance. The research concludes that while AI/ML offers significant potential for enhancing oncology trial compliance, successful integration requires clearer regulatory frameworks, improved system transparency, and cross-functional alignment between technical and compliance teams. These findings provide crucial insights for organizations navigating the complex landscape of AI/ML adoption in regulated clinical research environments
“For a Kid Like Me”: A Radio Documentary about the Impact of Autistic Representation in Film A Conversation about the Good, the Bad and the Ugly
Get PDFThis radio documentary examines the state of autism representation in media, specifically in Hollywood films. It contains a content analysis of twelve films, as well as interviews and opinions from autistic people and experts. The current depictions of autism on film are lacking in diversity and accuracy, oftentimes leading to misinformed perceptions of autism. This misinformed view results in a lack of diagnoses for people who do not conform to a male, white, heteronormative stereotype and people with different speech and intellectual abilities. Autistic people who are not savants with scientific special interests are also severely underrepresented in the media analysed. The interviews carried out add to the notion that a plural and diverse representation of autism in media can aid in the process of autism acceptance (rather than mere awareness) and improve the quality of life of ASD individuals of all kinds. The resulting documentary also highlights the reality that autism is not always visible and how that impacts mental health. To lead ASD people to the support they require, the documentary focuses on the lived experience of autism and how it compares to outward expression. Drawing on the “nothing about us without us” movement, this dissertation project concludes that autistic people should be involved in the creative process of narratives about autism
Biosimilars of Adalimumab In Eu: Addressing Regulatory Barriers and Market Dynamics to Enhance Accessibility and Affordability
Get PDFThe research examined regulatory obstacles together with market dynamics which affect EU adalimumab biosimilars adoption to enhance their market availability and economic value. The research examined regulatory variations together with market elements and pricing systems and stakeholder perspectives to create evidence-based solutions. A quantitative survey method served as the research methodology to gather data from healthcare professionals and policymakers and patient representatives across multiple EU member states. SPSS analysis of data included descriptive statistics as well as correlation and regression techniques.
The European Medicines Agency (EMA) centralised approval did not eliminate significant regulatory fragmentation. National policies regarding substitution practices together with reimbursement systems and procurement procedures determine how much biosimilar market adoption will take place. Germany and France showed high biosimilar adoption because their substitution and reimbursement policies were supportive yet Italy and Spain and Bulgaria showed slow adoption because their policies were restrictive and procurement systems were limited. The market dynamics played a significant role in biosimilar adoption because both transparent competitive tendering and originator companies' aggressive discounting and single-supplier contracts affected market competition.
Stakeholder opinions regarding biosimilars were influenced by knowledge deficits alongside safety concerns and patient unwillingness to transition from original products. The substitution policy and sustainable pricing strategies emerged as the leading determinants of EU policy harmonisation support according to the correlation analysis. The regression analysis showed that regulatory and market and stakeholder-related factors explain 28.1% of the variance in support for harmonisation indicating multiple barriers to adoption exist.
The study demonstrates that EU-wide standardised substitution and reimbursement systems combined with clear procurement methods and targeted educational initiatives for stakeholders will drive biosimilar acceptance by promoting trust and comprehension. The study advises that policy alignment should be supported while long-term multisupplier contracts should be established and savings from cost reduction should fund patient care and structured switching protocols with effective communication should be created.
The economic and accessibility benefits of EU adalimumab biosimilars depend on solving fragmented regulations and market inefficiencies. The EU will create a sustainable biosimilar market with universal access through unified policy reforms combined with stakeholder education and member state cooperation. The proposed method would reduce healthcare costs while extending access to treatment for patients suffering from chronic inflammatory condition
Assessment of Quality Control Processes in Genetically Engineered Cell Lines in Ireland: An Impact on Biopharmaceutical Product Consistency
Get PDFIntroduction: The growing complexity of biopharmaceutical products derived from genetically engineered cell lines necessitates robust quality control (QC) systems to ensure product consistency, safety, and efficacy. In Ireland, where the biopharmaceutical sector continues to expand, understanding how QC processes are applied and optimized is vital for maintaining regulatory compliance and public trust. This study explores the role of QC in genetically engineered cell line production and its influence on batch consistency, focusing on operational practices, challenges, innovations, and cost-effective strategies. Methods: A qualitative research approach was employed, guided by an interpretivist paradigm to capture the nuanced experiences of industry professionals. Data was collected through semi-structured interviews with seven QC professionals from various Irish biopharmaceutical firms. Purposive sampling ensured participants held relevant expertise. Thematic analysis was conducted following Braun and Clarke’s six-phase method, enabling the identification of patterns and themes that aligned with the study’s five objectives. Results: Six major themes and twenty-three subthemes were identified. Key findings revealed that QC significantly affects product consistency through SOP adherence, potency monitoring, and gene expression validation. Challenges included resource constraints, regulatory fragmentation, and training gaps. Innovative practices such as realtime monitoring, AI integration, and omics-based analysis are emerging as solutions, although barriers like cost and infrastructure remain. Cost-effective strategies such as multi-use systems, shared resources, and outsourcing were highlighted, especially for small-to-medium enterprises. Ethical and societal responsibilities were also seen as integral to modern QC. Conclusions: The study contributes meaningful insights into how QC is practiced in Ireland’s biopharmaceutical sector, confirming that robust, adaptive, and ethically aligned QC systems are essential for consistent and compliant biomanufacturing. It recommends harmonization of standards, investment in training, and broader adoption of innovative and lean QC practices. These findings support policy, operational, and academic improvements in global QC systems
Consumer Perceptions of Sustainability and Their Impact on Purchasing Decisions in the Indian Textile Industry
Get PDFThe textile industry has been under tremendous pressure in recent years to adopt the sustainable practices due to surging consumer awareness and ecological concerns. The objective of this study is to explore consumer perceptions towards sustainability in textile products with respect to their purchasing behaviour, influences on decisions made as well as obstacles faced by them. To attain this purpose, the research employed qualitative research design through semi-structured interviews conducted on five participants who were identified from different market segments within the textile industry. The participants of the study included both consumers and professionals from different industries which provided a much broader perspective. Semi- structured interviews were used as means of data collection that were thereafter transcribed and analysed manually using thematic analysis technique with an aim of coming up with major themes and patterns concerning sustainable development.
From these findings, it is evident that there are several factors that affect buying behaviour of consumers such as sustainability in relation to purchase decision making process. Interviewees emphasized the need for eco-friendly materials, ethical ways of production and transparency across supply chains thus they are more likely to support brands showing moral responsibility. Consumer inclination towards brands that show real commitment to sustainable activities is on the rise, and they often rely on certifications and detailed product information to make informed decisions. However, there are several hurdles for sustainability textiles widespread adoption. High costs and the limited availability of sustainable options are major barriers, especially for budget-constrained consumers or people residing in areas where such products are not easily accessed.
This research also points out marketing and consumer trust as other important concerns. A good marketing strategy should be able to communicate clearly how sustainable a product is such that it builds consumer confidence. Nevertheless, there exist a fear over greenwashing whereby companies provide false claims about their efforts in being eco-friendly. In conclusion, this research offers valuable insights into consumer perceptions of sustainability within the textile industry thus identifying some areas which need serious improvements. By dealing with these kinds of blockages as well as enhancing openness, the business will be more capable of meeting customer expectations while driving better ways of operating sustainably
Analysing The Influencers of Brand Loyalty in the Fast Fashion Retailing in Dublin
Get PDFThis research explores the key influencers of brand loyalty in the fast fashion retail industry in Dublin, with a specific focus on student consumers. Brand loyalty is recognized as crucial for businesses, as it drives sales, customer retention, and long-term growth. The fast fashion industry in Dublin is rapidly expanding, with students displaying a strong interest in fashion products. This study examines how various factors such as product quality, pricing, and brand ethics influence loyalty among these young consumers.
A mixed-method approach was employed to gather data. Quantitative data were collected through surveys distributed to students in Dublin, while qualitative insights were obtained through interviews with industry experts. This methodology allowed for a comprehensive understanding of the factors that drive brand loyalty, providing a balanced view of both consumer behavior and business strategies. The data were analyzed to identify patterns and trends, offering a clear picture of how loyalty programs, ethical practices, and pricing strategies affect student loyalty in the fast fashion sector.
The findings suggest that sustainable practices, ethical sourcing, and maintaining affordable yet trendy fashion options are key to fostering brand loyalty. Companies that align their business models with these values are better positioned to retain customers and build long-term loyalty. The research concludes by offering recommendations for fast fashion retailers to adopt sustainability initiatives, exclusive collections, and enhanced loyalty programs to ensure continued growth and competitiveness in Dublin's fast fashion market
Exploring the Impact of Financial Literacy on Digital Banking Adoption Among Rural Population in India
Get PDFThis study investigates the impact of financial literacy on the adoption of digital banking services among rural population in India. The primary objective was to understand how both subjective and objective financial literacy influence rural users' willingness and ability to engage with digital banking technologies. To achieve this, a quantitative approach was employed using structured surveys to collect data from rural participants. The research utilized SPSS software for data analysis, focusing on regression techniques to explore the relationships between financial literacy and digital banking adoption.
The findings reveal a nuanced impact of financial literacy on digital banking adoption. Hypothesis 1, which posits that subjective financial literacy positively influences digital banking adoption, is partially supported. Specifically, understanding financial terminology used in digital banking was found to significantly affect adoption rates. However, other subjective factors, such as confidence in financial management and decision-making trust, did not demonstrate a significant impact.
Conversely, Hypothesis 2, suggesting that objective financial literacy positively impacts digital banking adoption, is strongly supported. The study identifies significant predictors of digital banking adoption, including financial calculation skills, understanding of financial products, and awareness of financial risks. These factors align with the hypothesis and underscore the critical role of actual financial knowledge in facilitating digital banking usage.
Overall, the results highlight that while subjective financial literacy contributes to digital banking adoption, objective financial literacy has a more pronounced effect. These insights suggest that while improving subjective financial knowledge is valuable, enhancing objective financial skills is crucial for promoting digital banking, especially in rural areas. The study provides valuable guidance for designing targeted financial education initiatives and strategies to improve digital banking adoption among rural populations in India.
The research underscores the need for comprehensive financial education programs that address both subjective and objective aspects of financial literacy. Future initiatives should focus on practical financial skills and awareness of financial risks to effectively promote digital banking adoption in rural communitie
Evaluating Factors Influencing Sustainable Food Consumption Among International Students In Ireland
Get PDFAs worries about the environment and resource scarcity have grown, sustainable practices have
become more important not only for organizations but also for the global society. International
students represent a diverse population who contribute significantly to the food system in Ireland.
This dissertation investigated the factors that influence the consumption of sustainable food
among international students in Ireland, with a focus on the motivations driving their choices as
well as the barriers they face. The study used mixed-methods, combining quantitative surveys in
the form of questionnaire collected from 54 international students in Ireland, and qualitative
interviews within 4 other students to gain a thoroughly understanding of their attitudes,
behaviours, and challenges.
The findings revealed that key motivations for sustainable food consumption include health
consciousness, environmental consciousness, and social influences, particularly the alignment
with the values of the society they live within. The study also highlighted the role of institutional
supports and the influence of pride/guilt feelings on students' purchase intentions. Besides,
although students' diet is strongly shaped and influenced by their cultural background, they are
also receptive to sustainable eating habits from other cultures.
On the other hand, barriers to their sustainable food consumption intention include the high price
of sustainable food products, and the mistrust in the sustainable labelling system, while
unavailability does not seem to be a significant barrier that prevents international students in
Ireland from making more sustainable food choices.
Based on the findings, the dissertation offered several recommendations for stakeholders. For
policymakers, the emphasis is on creating policies that enhance the accessibility and affordability
of sustainable food. Educational institutions are encouraged to integrate sustainability into their
curricula and campus life. Food service providers are urged to offer more culturally diverse and
affordable sustainable food options.
In conclusion, this research contributed to the understanding of sustainable food consumption in
a multicultural context and offered practical recommendations to support international students
in making sustainable food choices. Reflecting on this research journey, the author has gained
significant insights into the complexities of sustainable food practices and the importance of
interdisciplinary approaches in addressing global challenges
Exploring The Impact of Brexit on Consumer Purchase Intention for Reshored Food Brands in Ireland
Get PDFThis thesis investigates the impact of Brexit on consumer purchase intentions towards reshored food brands in Ireland, emphasizing how the economic and regulatory changes influence consumer behaviors. Utilizing quantitative data gathered from structured questionnaires, the study highlights significant shifts in consumer preferences towards locally produced foods following Brexit. The findings suggest that the introduction of trade barriers and the consequent reshoring of food brands have been positively received by consumers, who associate these local products with superior quality and dependability. This research underscores the reshoring's positive impact on the Irish food market and offers strategic recommendations for producers and policymakers to strengthen the competitiveness of local food brands in a post-Brexit economy