Osmaniye Korkut Ata University Academic Repository
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Hydrogen economy: From upstream (production) to downstream (application)
No full textThe escalating energy demands of emerging economies, coupled with growing environmental concerns, have spurred a global shift toward renewable and clean energy sources. Central to this transition is hydrogen (H2) energy, emerging as a pivotal clean energy carrier for the new century. Characterized by its high energy density, substantial energy content, and high gravimetric density, H2 stands out for its relatively clean production methods. Crucially, H2 energy is anticipated to play a transformative role in energy storage, positioning it as a key player in achieving net-zero carbon dioxide emissions, a vital response to the pressing global climate crisis. However, the widespread adoption of H2 energy systems is currently hindered by their high cost. Therefore, effective governance of the H2 economy is essential to facilitate the utilization of H2-based energy systems. This book chapter meticulously explores the H2 economy, providing a wide examination from its upstream production to downstream applications. These applications allow for a comprehensive understanding of the H2 value chain, from its production methods to different applications in various sectors. This also helps identify challenges and opportunities at each stage of the H2 economy. Because transition to a H2 economy depends on overcoming these challenges and promoting the widespread adoption of H2 in various sectors. © 2025 Elsevier Inc. All rights reserved
Introduction: the evolution of functional foods and novel bioactives
No full textFunctional foods have undergone significant changes over time, with their historical importance rooted in different cultures and their definition expanding to include various products. These foods play a vital role in addressing nutritional deficiencies and enhancing overall health. The presence of bioactive compounds like antioxidants, polyphenols, and probiotics contributes to their health benefits, including antioxidant effects and improvement of gut health. A primary area of interest in current research involves investigating the effects of functional foods on chronic diseases, with a particular emphasis on their potential health benefits. Ongoing clinical trials and proposed research directions play a pivotal role in advancing this field of study. Technological advancements have also played a role in the development of functional foods, allowing for the inclusion of new bioactive ingredients and responding to market trends and consumer preferences. The sector has witnessed advancements through the integration of new bioactive substances, as well. But, the implementation of stringent regulatory measures is crucial to guarantee the safety and effectiveness of these developments. Despite these achievements, the industry encounters obstacles in terms of scientific investigation, consumer awareness, and adherence to regulations. However, there are substantial prospects for expansion through international cooperation and the creation of inventive functional food items that cater to various consumer demands. This offers a promising avenue for tackling public health issues and enhancing overall wellness. © 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies
JAK inhibitor Baricitinib Attenuates Kidney Injury in Sepsis Model Induced by Cecal Ligation and Puncture
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The relationship between the spirituality levels and the happiness and life satisfaction of elderly individuals living in their homes and nursing homes
No full textSpirituality and religion have an important place in the lives of Turkish elderly people. With modernization and changes in social life, the position of Turkish elderly people at home has changed and the need for institutional care has increased. Elderly individuals who have partially lost their place in traditional Turkish culture often resort to spirituality in coping with the problems they experience. This situation requires conducting studies on determining and comparing the relationship between the spirituality levels, happiness and life satisfaction of elderly individuals living at home or in nursing homes in our country. The sample of the study consisted of 139 elderly individuals over the age of 65 who were followed in nursing homes and Family Health Centers. The data of the research were collected by face-to-face interview technique using the Personal Information Form, Spirituality Scale, Life Satisfaction Scale and Subjective Happiness Scale. The research revealed that there is a significant difference between the spirituality levels of elderly individuals living in homes and nursing homes. It also showed that, although there was no significant difference, the life satisfaction and happiness levels of elderly individuals living at home were higher than those of elderly individuals living in a nursing home
Yazılım Firmalarının Değerini Etkileyen Faktörler: NASDAQ’da İşlem Gören Yazılım Firmaları Üzerine Uygulamalı Bir Yaklaşım
No full textThis study aims to determine the factors affecting the valuation of modern software companies. In this direction, an analysis was carried out on 97 companies traded on NASDAQ and operating in the software industry. To determine the necessary data within the scope of the study, a set of questions was first created and the content analysis method, one of the qualitative research methods, was used to reach the answers to these questions. In this process, the official websites, annual reports, financial reports and sustainability reports of the identified companies were analyzed in detail. In the analysis phase of the research, the multiple linear regression method was applied. According to the findings of the analysis, it was determined that the increase in the number of employees, engineer staff, technological competence, intangible fixed assets, staff development quality, growth strategy, risk management activities, donation and social responsibility activities, sales growth and net profit increase, which are among the independent variables, significantly affect the value of software companies.Bu çalışmada, modern yazılım firmalarının değerlemesini etkileyen faktörlerin belirlenmesi amaçlanmaktadır. Bu doğrultuda, NASDAQ’da işlem gören ve yazılım sektöründe faaliyet gösteren 97 şirket üzerinde bir analiz gerçekleştirilmiştir. Çalışma kapsamında gerekli verilerin tespit edilmesi amacıyla öncelikle bir soru seti oluşturulmuş ve bu soruların yanıtlarına ulaşmak için nitel araştırma yöntemlerinden içerik analizi yöntemi kullanılmıştır. Bu süreçte, belirlenen şirketlerin resmi internet siteleri, faaliyet raporları, finansal raporları ve sürdürülebilirlik raporları detaylı bir şekilde incelenmiştir. Araştırmanın analiz aşamasında ise çoklu doğrusal regresyon yöntemi uygulanmıştır. Analiz bulgularına göre, bağımsız değişkenler arasında yer alan çalışan sayısındaki artış, mühendis kadrosu, teknolojik yetkinlik, maddi olmayan duran varlıklar, personel gelişim kalitesi, büyüme stratejisi, risk yönetimi çalışmaları, bağış ve sosyal sorumluluk faaliyetleri, satış büyümesi ve net kâr artışı gibi unsurların yazılım firmalarının değerini anlamlı bir şekilde etkilediği belirlenmiştir
Therapeutic Potential of Irisin in Ovarian Torsion-Detorsion: Mitigating Oxidative Stress and Inflammatory Response
No full textObjective: Ovarian torsion (OT) is a critical gynecological emergency marked by partial or complete rotation of the ovary around its ligamentous supports, resulting in impaired blood flow and potential ischemic injury or necrosis if not treated promptly. This study explores the potential of irisin in mitigating ischemia-reperfusion (I/R) injury following ovarian torsion-detorsion (T/D), with a focus on oxidative stress and inflammatory mediators. Methods: Twenty-four female Sprague-Dawley rats were allocated into three groups: Sham, T/D, and irisin 10 mu g/kg. Oxidative stress markers-total oxidant status (TOS), oxidative stress index (OSI), malondialdehyde (MDA), and myeloperoxidase (MPO)-were measured to assess tissue damage. Antioxidant parameters, including superoxide dismutase (SOD) activity and total antioxidant status (TAS) were evaluated. Serum levels of tumor necrosis factor-alpha (TNF-alpha) and interleukin-1 beta (IL-1 beta) were analyzed to assess systemic inflammation and irisin's modulatory role. Results: The T/D group showed elevated MPO and MDA levels relative to the sham group (p<.05), alongside significant reductions in SOD activity and TAS levels (p<.05). Irisin administration reversed these imbalances, decreasing MPO and MDA levels and enhancing SOD and TAS levels (p<.05 vs. T/D group). TNF-alpha and IL-1 beta levels, which were significantly elevated in the T/D group, were reduced by irisin treatment (p < .05 vs. T/D group), indicating its anti-inflammatory efficacy. Conclusion: The findings support the potential of irisin as a therapeutic agent for mitigating oxidative stress and inflammation in ovarian I/R injury. Irisin may offer clinical benefits in preserving ovarian function during conditions related to T/D
HERBAL POWER: ANTIMICROBIAL, ANTIOXIDANT AND ANTICHOLINESTERASE PROPERTIES OF CITRULLUS COLOCYNTHIS
No full textCitrullus colocynthis (L.) Schrad. is a biologically rich plant widely used in traditional medicine. This study aimed to investigate the antimicrobial, antioxidant and anticholinesterase potential and phenolic/flavonoid contents of C. colocynthis. Antimicrobial tests using ethanol and methanol extracts revealed that it exhibited strong antimicrobial effects especially against pathogens such as Staphylococcus aureus, Candida albicans, C. krusei and Acinetobacter baumannii. In addition, antioxidant activity tests showed that ethanol extract had high antioxidant capacity, while methanol extract was moderately effective. Phenolic and flavonoid content analyses showed that ethanol extract contained higher phenolic and flavonoid components. In addition, anticholinesterase activity tests showed that C. colocynthis extract exhibited a significant anticholinesterase effect, which could potentially be useful in the treatment of neurological diseases. These findings indicate that C. colocynthis is a potent natural resource with potential therapeutic benefits and its antimicrobial, antioxidant and anticholinesterase properties are of considerable importance in biomedical applications
Peer and instructor feedback on pre-service EFL teachers' reflection types and levels in video-mediated microteaching
No full textThis study explored the role of peer and instructor feedback on pre-service EFL teachers' reflection types and levels during a video-mediated microteaching process. While previous research has examined various aspects of reflection and feedback in teacher education, there is currently a lack of studies specifically investigating how instructor and peer feedback shape the types and levels of reflection pre-service teachers engage in through video-mediated microteaching in the EFL context. The participants included 34 third-grade pre-service EFL teachers who performed weekly microteaching sessions. Data collected via qualitative tools were analysed through thematic analysis. Participants initially lacked critical engagement in reflection, focusing primarily on content delivery. However, they became more evaluative in their reflections by engaging in process and premise reflections, particularly in the post-video phase, as a result of listening to recorded teacher and peer feedback and engaging in group discussions. The findings suggest that while microteaching alone was insufficient for fostering deep reflection, the combination of video recordings and constructive peer and instructor feedback guided preservice teachers towards higher levels of reflection, such as analytical and critical/evaluative reflection. The study highlights the importance of structured feedback opportunities in teacher education programs to cultivate habits of ongoing professional growth among pre-service teachers
Huzurevinde Yaşayan Yaşlılarda Sarkopeni Riski ve Malnütrisyon ile Etkileyen Faktörlerin Belirlenmesi
No full textAmaç: Yaşlı popülasyonun gün geçtikçe artış göstermesi birçok sorunu da beraberinde getirmektedir. Bu çalışmanın amacı huzurevinde yaşayan yaşlılarda bu sorunlardan biri olan sarkopeni riski ve malnütrisyon durumunu incelemek ve etkileyen faktörleri belirlemektir. Gereç ve Yöntem: Tanımlayıcı ve kesitsel tipte yapılan araştırma Haziran 2023-Ocak 2024 tarihleri arasında bir huzurevinde yaşayan 115 yaşlı ile yapıldı. Veriler yüz yüze görüşme tekniği ile Kişisel Bilgi formu, Mini Nütrisyonel Araştırma Formu Kısa ve Uzun Form (MNA), Sarkopeni Teşhisi İçin Basit Hızlı Anket (SARCF)kullanılarak toplandı.Görüşmeler yaklaşık 30 dakika sürdü. Bulgular: Yaşlıların yaş ortalamasının 75,03±6,86 ve büyük çoğunluğunun erkek olduğu (%67,8) tespit edildi. Yaşlıların MNA kısa forma göre %51,3’ünün; MNA uzun forma göre %47,8’inin malnütrisyon riski veya malnütrisyonu olduğu;%63,5’inin ise sarkopeni açısından riskli olduğu belirlendi. Kronik hastalığı bulunan yaşlıların MNA kısa form puanı 10,75±2,32 iken kronik hastalığı bulunmayanların puanı 11,57±2,72 olarak tespit edildi (p<0,05). Kadın ve erkek yaşlıların SARC-F puanının sırasıyla 5,00±1,56 ve 3,91±2,76 olduğu ve bu farkın sarkopeni riski açısından anlamlı olduğu belirlendi (p<0,05). Ayrıca günlük bir litreden daha az sıvı tüketenlerin sarkopeni açısından daha riskli olduğu saptandı (p<0,05). Sarkopeni risk skoru ile MNA kısa ve MNA uzun form arasında istatistiksel olarak anlamlı bir ilişkinin olduğu tespit edildi (p<0,05). Sonuç: Yaşlıların çoğunluğunda malnütrisyon/malnütrisyon riski ve sarkopeni riskinin bulunduğu tespit edildi. Huzurevinde yaşayan yaşlılarda malnütrisyon durumu ile sarkopeni durumları arasındaki ilişkiyi irdeleyen daha geniş örnekleme sahip araştırma yapılarak literatüre katkı sağlanması önerilmektedir
Çevre eğitiminin spor bilimleri fakültesi öğrencilerine kazandırdığı çevresel motivasyonun incelenmesi: 10 haftalık kontrollü çalışma
No full textThe aim of this study is to examine the effect of environmental education given about natural habitats on the environmental motivation of sports sciences faculty students. In the 2023-2024 academic year, 116 volunteer students (64 male, 52 female) enrolled in the volunteering studies and field experience course at Kırıkkale University, Faculty of Sport Sciences, participated in the study. The “Motivation Scale for Environmental Motivation” developed by Sakarya (2010) was used to collect the data. During the research process, a 10-week theoretical and practical training was given. Pre-test and post-test data on gender, socio-economic status, and anthropometric characteristics of the students were obtained. The results of the analysis show that the environmental motivation of individuals who received environmental education within the scope of volunteering activities and field experience courses increased significantly. Both male and female participants showed significant improvements in the sub-dimensions of environmental motivation. In conclusion, environmental education increases individuals' environmental sensitivity and encourages the sustainable use of natural resources. These findings reveal the effectiveness of education about our environment, nature, and living spaces in developing motivation towards the environment.Bu çalışmanın amacı, doğal yaşam alanlarına yönelik verilen çevre eğitiminin spor bilimleri fakültesi öğrencilerinin çevresel motivasyonları üzerindeki etkisini incelemektir. Araştırmaya, 2023-2024 eğitim-öğretim yılında Kırıkkale Üniversitesi Spor Bilimleri Fakültesinde gönüllülük çalışmaları ve alan deneyimi dersine kayıtlı 116 gönüllü öğrenci (64 erkek, 52 kadın) katılım sağlamıştır. Verilerin toplamasında Sakarya (2010) tarafından geliştirilen "Çevreye Karşı Motivasyon Ölçeği" kullanılmıştır. Araştırma sürecinde 10 haftalık teorik ve uygulamalı bir eğitim verilmiştir. Öğrencilerin cinsiyet, sosyo ekonomik durum ve antropometrik özelliklerine dair ön test ve son test verileri elde edilmiştir. Analiz sonuçları, gönüllülük çalışmaları ve alan deneyimi dersi kapsamında çevre eğitimi alan bireylerin çevresel motivasyonlarının anlamlı şekilde arttığını göstermektedir. Hem erkek hem de kadın katılımcılarda çevresel motivasyon alt boyutlarında önemli gelişmeler kaydedilmiştir. Sonuç olarak, çevre eğitimi, bireylerin çevresel duyarlılıklarını artırmakta ve doğal kaynakların sürdürülebilir kullanımını teşvik etmektedir. Bu bulgular, çevremize, doğamıza, yaşam alanlarımıza yönelik eğitiminin çevreye karşı motivasyon geliştirmekteki etkinliğini ortaya koymaktadır