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Biomedical text-based detection of colon, lung, and thyroid cancer: A deep learning approach with novel dataset
No full textPre-trained Language Models (PLMs) are widely used nowadays and increasingly popular. These models can be used to solve Natural Language Processing (NLP) challenges, and their focus on specific topics allows the models to provide answers to directly relevant issues. As a sub-branch of this, Biomedical Text Classification (BTC) is a fundamental task that can be used in various applications and is used to aid clinical decisions. Therefore, this study detects colon, lung, and thyroid cancer from biomedical texts. A dataset including 3070 biomedical texts is generated by artificial intelligence and used in the study. In this dataset, there are 1020 texts labeled colon cancer, while the number of samples labeled lung and thyroid cancer is equal to 1020 and 1030, respectively. In the study, 70 % of the data is used in the training set, while the remaining data is split for validation and test sets. After preprocessing all the data used in the study, word encoding is used to prepare the model inputs. Furthermore, these documents in the dataset are converted into sequences of numeric indices. Afterward, Long Short-Term Memory (LSTM), Gated Recurrent Unit (GRU), Bidirectional LSTM (BiLSTM), LSTM+LSTM, GRU+GRU, BiLSTM+BiLSTM, and LSTM+GRU+BiLSTM architectures are trained with train and validation sets, and these models are tested with the test set. Both validation and test performances of all developed models are determined, and a Graphical User Interface (GUI) software is prepared in which the most successful architecture has been embedded. The results show that LSTM is the most successful model, and the accuracy and specificity values achieved by this model in the validation set are equal to 91.32 % and 95.67 %, respectively. The F1 score value achieved by this model for the validation set is also equal to 91.32 %. The accuracy, specificity, and F1 score values achieved by this model in the test set are equal to 85.87 %, 92.94 %, and 85.90 %, respectively. The sensitivity values achieved by this model for the validation and test set are 91.33 % and 85.88 %, respectively. These developed models both provide comparative results and have shown successful performances. Focusing these models on specific issues can provide more effective results for related problems. Furthermore, the presentation of a user-friendly GUI application developed in the study allows users to use the models effectively
A REVİEW ON AUJESZKY'S DİSEASE
No full textAujeszky hastalığı, ya da diğer adıyla Pseudorabies, Suid Alphaherpesvirus 1 tarafından oluşturulan ve domuzlar başta olmak üzere birçok memeli hayvanda enfeksiyonlara yol açan viral bir hastalıktır. Pseudorabies virüsü, Herpesviridae ailesinin Alphaherpesvirinae alt ailesine ait olup, domuzlar bu virüsün doğal konakçısıdır. Enfeksiyon, özellikle domuz yavrularında nörolojik bozukluklara, erişkin dişi domuzlarda ise infertiliteye neden olmaktadır. Virüs, sinir sistemi aracılığıyla yayılarak, enfekte hayvanlar arasında ağız ve burun salgıları yoluyla doğrudan temasla bulaşmaktadır. Aujeszky hastalığı, dünya genelinde büyük ekonomik kayıplara yol açmakta ve özellikle Latin Amerika, Afrika, Asya ve Doğu Avrupa gibi bölgelerde yaygın olarak görülmektedir. Bu derleme makale, Pseudorabies virüsünün etiyolojik özelliklerini, patogenezini, klinik bulgularını, epidemiyolojik yayılımını ve kontrol yöntemlerini incelemektedir.Aujeszky's disease, also known as Pseudorabies, is a viral infection caused by Suid Alphaherpesvirus 1, which affects many mammalian species, with pigs being the primary host. The Pseudorabies virus belongs to the Alphaherpesvirinae subfamily of the Herpesviridae family, with pigs serving as its natural host. The infection leads to neurological disorders, particularly in piglets, and infertility in adult sows. The virus spreads through the nervous system and is transmitted by direct contact with oral and nasal secretions between infected animals. Aujeszky's disease causes significant economic losses worldwide and remains prevalent, especially in regions such as Latin America, Africa, Asia, and Eastern Europe. This review article examines the etiological characteristics, pathogenesis, clinical manifestations, epidemiological spread, and control methods of the Pseudorabies virus
An environmental assessment of non-renewable, modern renewable, and combustible renewable energy in Cameroon
No full textGlobal environmental concerns have led countries to take action to transition to renewables. In this context, countries have begun to change their energy patterns to achieve ecological sustainability through the adoption of clean energy sources. Therefore, this study explores the impact of the energy mix on the ecological footprint by using the Fourier ADL and ARDL models for Cameroon from 1980 to 2018. To test the impact of the energy mix, the study adopts non-renewable energy, modern renewable energy, as well as combustible renewables and waste. The empirical findings reveal that GDP and electricity generation from non-renewable energy sources contribute the most to environmental deterioration in Cameroon. Modern renewables and combustible renewables and waste contribute significantly to environmental sustainability and reduce the ecological footprint. This implies that increased use of renewable energy sources, especially modern renewables, can help Cameroon achieve its renewable energy target and contribute to environmental sustainability. To mitigate the harmful impacts of non-renewable energy sources, the country should promote increasing the share of combustible renewables in its energy mix as a clean substitute
First-principles calculations to investigate the structural, elastic and thermodynamic properties of full-Heusler MgXY2 (X = Zn, Cd, Y = Ag Au, Cu) compounds
No full textMagnesium and its compounds are recognized as favorable materials for structural uses, primarily due to their lightweight nature and remarkable specific strength. This research employed first-principles methodologies to investigate how pressure affects the crystal structure along with the elastic and thermodynamic characteristics of MgXY2 ( X = Zn, Cd, and Y = Ag, Au, Cu) compounds. All analyses were implemented via the Perdew-Burke-Ernzerhof variant of the Generalized Gradient Approximation alongside a plane-wave ultrasoft pseudopotential approach. The findings on the elastic constants indicated that these MgXY2 compounds have maintained their stability at pressures up to 500 kBar. These constants informed detailed assessments of properties like elastic modulus, Poisson's ratio, Vickers hardness, and material anisotropy. The Quantum Espresso software was utilized to calculate melting points, Debye temperature, and minimum thermal conductivity values. A temperature range spanning from 0 to 800 K allowed for an evaluation of vibrational energy, free energy, entropy, and specific heat capacity metrics. The anticipated physical attributes suggest significant potential for these magnesium compounds in biomedical fields. (c) 2025 Chongqing University. Publishing services provided by Elsevier B.V. on behalf of KeAi Communications Co. Ltd. This is an open access article under the CC BY-NC-ND license ( http://creativecommons.org/licenses/by-nc-nd/4.0/ ) Peer review under responsibility of Chongqing UniversityNational Center for High Performance Computing (UHeM) [1012332022]The computational resources used in this study were pro-vided with the support of the National Center for High Per-formance Computing (UHeM) #1012332022#
Influence of Using SiC and Al2O3 Ceramic Front Layer on Ballistic Performance of a Bainitic Steel: A Comparative Study
No full textDevelopment of lightweight armors is vital in order to provide ballistic protection in a more effective way. The weight of steel armor can be decreased significantly by setting a front ceramic layer on it. In this paper, the influence of utilizing SiC and Al2O3 ceramic front layer on the ballistic behavior of 4140 bainitic steel was investigated experimentally. All steel plates were initially subjected to the austempering treatment by applying the austenitization at 860 degrees C for 1 h and then holding in a salt bath at 343 degrees C for 50 min to get fully bainitic microstructure. And then, the laminated composites, consisting of SiC or Al2O3 front layer (50 x 50 mm in size) and bainitic steel backing layer, were prepared by joining these layers with an acrylic adhesive. After the mechanical and microstructural characterization of the bainitic steel, the ballistic shots were made using 7.62 x 51 mm AP projectile with an average speed of 788.4 m/s on both monolithic steel and layered armor samples for comparison. The samples, which stopped the bullet at normal impact condition without complete perforation or disintegration of the bainitic steel layer, were termed as successful. The bainitic steel achieved the ballistic protection at a thickness >= 14 mm but the use of SiC layer provided the weight saving of at least 42.9% and the Al2O3 front layer enabled the weight reduction of 28.6% in the armor with respect to the monolithic 4140 bainitic steel
Some biological activities of Thalictrum minus (Ranunculaceae)
No full textPlants are vital natural resources that are used in a wide range of applications. Throughout history, these tools have proven to be valuable assets for individuals. We conducted a study to assess the biological activity of the aerial portions of Thalictrum minus L. In this particular situation, the plant's ethanol and methanol extracts were obtained using Soxhlet equipment. The Rel Assay kits were used to measure the total antioxidant status (TAS), total oxidant status (TOS), and oxidative stress index (OSI). The antiproliferative effectiveness against the A549 lung cancer cell line was assessed using the MTT test. The anticholinesterase activity was assessed by measuring the activities of acetylcholinesterase and butyrylcholinesterase. The plant's ethanol and methanol extracts were analyzed, and their TAS values were determined to be 4.371±0.083 and 4.027±0.081, respectively. The TOS values were determined to be 11.816±0.121 and 13.580±0.176, respectively, whereas the OSI values were determined to be 0.271±0.007 and 0.337±0.009. The antiproliferative activity of the methanol extract of the plant was found to be greater than that of the ethanol extract. The ethanol extract had an anti-AChE value of 58.90±1.41, while the methanol extract had an anti-AChE value of 65.11±1.01. Similarly, the ethanol extract had an anti-BChE value of 72.25±0.79, while the methanol extract had an anti-BChE value of 85.79±0.68. Consequently, it was established that the plant has antioxidant, anticancer, and anticholinesterase properties. © 2025 Pamukkale University. All rights reserved
IAD Values in Relation to Physiological Storage Disorders of 'Honeycrisp' Apples
No full textThe 'Honeycrisp' apple is highly prone to developing physiological disorders such as soft scald, bitter pit, and core browning during storage, but disorder incidences are affected by fruit maturity stage. To investigate relationships between fruit maturity and physiological disorders, a difference of absorbance meter was used to separate fruit into index of absorbance difference (IAD) value categories with the objective of reducing fruit-to-fruit variability within a population of fruit harvested at any one time. Fruit from two harvest dates, 10 days apart, were separated by IAD values and stored at 0.5 or 3 degrees C. The internal ethylene concentration (IEC) of fruit during storage and the incidence of physiological disorders after 18 weeks were assessed. The results indicate that earlier harvest, colder storage temperature, and lower IAD values (less green fruit) were associated with lower IECs during storage. The incidences of soft scald, bitter pit, and core browning, as well as superficial scald, were affected by IAD values within each harvest date and storage temperature, and more precisely than an evaluation of bulked fruit samples. This study highlights the potential of categorizing fruit by IAD values as a tool to minimize variation of fruit within a population and therefore increase sensitivity of investigations into factors affecting storage performance.TUBITAK; National Institute of Food and Agriculture, US Department of Agriculture [1001075, NE1836]A.T.O. was funded by a TUBITAK 2219 fellowship grant. In addition, this work was supported by the National Institute of Food and Agriculture, US Department of Agriculture, Multistate (award nos. 1001075 and NE1836) Improving Quality and Reducing Losses in Specialty Fruit Crops through Storage Technologies
Life cycle assessment of photovoltaic systems of various sizes: An environmental and economic perspective on an educational building in a hot climate
No full textThe swift adoption of photovoltaic systems in buildings is driven by the need for sustainable energy solutions and decarbonization goals. This study assesses a faculty building’s energy usage, potential energy yield, life cycle costs, and carbon emissions. Key factors such as building characteristics, operational schedules, and load profiles were analyzed using DesignBuilder. Photovoltaic system modeling with PVsyst explored various ground cover ratios (GCR). Life cycle cost analysis highlighted the economic advantages of photovoltaic systems, while carbon payback periods measured emission reductions. Results indicate that higher GCRs enhance energy production and revenue from grid sales. Performance ratio values varied between 77% and 79%, and the specific production rate ranged from 1630 to 1672 kWh/kWp. Although initial investment is high, increasing GCR reduces life cycle costs and shortens payback periods. Payback period was found to be 6.5 years, and the building achieves carbon neutrality within the first year. This methodology can be adapted for various building types and climates, supporting the broader goal of zero energy buildings and carbon emission reduction
Integration of material procurement and stock management with bim (building information modeling) in construction management processes
Full text linkBu çalışmada, inşaat projelerinde Yapı Bilgi Modellemesi (BIM) kullanılarak malzeme tedarik ve stok yönetimi süreçleri incelenmiştir. Günümüzde inşaat projeleri giderek daha karmaşık hale gelmekte ve kaynakların etkin yönetimi kritik bir önem taşımaktadır. Bu bağlamda, BIM teknolojisinin sunduğu 3B ve 4B modelleme ile proje süreçlerinin daha verimli bir şekilde yönetilmesi sağlanabilmektedir. Çalışma kapsamında Niğde ili, Çamardı ilçesinde yer alan 12 adet villadan oluşan bir site projesi ele alınmış, bu proje üzerinde BIM ve MS Project yazılımları kullanılarak malzeme tedarik planlaması ve stok yönetimi gerçekleştirilmiştir. Öncelikle, seçilen proje Revit yazılımı kullanılarak 3B olarak modellenmiş, ardından MS Project ile iş programı oluşturularak 4B modelleme entegrasyonu sağlanmıştır. Proje sürecinin detaylı bir şekilde planlanması amacıyla iş akışları oluşturulmuş, mevsimsel ve lojistik faktörler göz önünde bulundurularak malzeme tedarik süreci planlanmıştır. BIM 4B boyutunun entegrasyonu, iş programı ile malzeme yönetiminin uyum içinde ilerlemesini sağlamış ve proje sürecinde gecikmelerin önlenmesine katkıda bulunmuştur. Elde edilen bulgular, BIM tabanlı 3B ve 4B modelleme kullanılarak oluşturulan iş planının, zaman yönetimi, maliyet kontrolü ve malzeme yönetimi açısından önemli avantajlar sunduğunu göstermektedir. Çalışmada ayrıca, BIM'in malzeme stok yönetimine etkisi detaylı olarak incelenmiş, sahada malzeme depolama alanlarının 3B model üzerinde görselleştirilmesi sağlanarak malzeme lojistiğinin daha sistematik ve kontrollü hale getirildiği belirlenmiştir. Sonuç olarak, BIM teknolojisinin inşaat projelerindeki yaygınlaşması, planlama süreçlerinde daha verimli ve hatasız bir yönetim sunmaktadır. Ancak, BIM'in etkin kullanılabilmesi için eğitim, mevzuat düzenlemeleri ve sektör adaptasyonu gibi faktörlerin geliştirilmesi gerektiği vurgulanmaktadır. Bu çalışmanın bulguları, BIM 3B ve BIM 4B teknolojilerinin inşaat projelerinde daha geniş bir uygulama alanına yayılması gerektiğini ortaya koymaktadır. Anahtar Kelimeler: Yapı Bilgi Modellemesi (BIM), Proje Yönetimi, Malzeme Tedarik Planlaması, Stok Yönetimi, MS Project, 4B Modelleme.In this study, material procurement and inventory management processes were examined using Building Information Modeling (BIM) in construction projects. Today, construction projects are becoming increasingly complex, and effective resource management is of critical importance. In this context, BIM technology offers 3D and 4D modeling to enable more efficient management of project processes. The study focused on a site project consisting of 12 villas located in the Çamardı district of Niğde province. Material procurement planning and inventory management were carried out using BIM and MS Project software on this project. Firstly, the selected project was modeled in 3D using Revit software, and then a work schedule was created using MS Project to integrate 4D modeling. Workflows were created to plan the project process in detail, and the material procurement process was planned taking into account seasonal and logistical factors. The integration of the BIM 4D dimension ensured that the work schedule and material management progressed in harmony, contributing to the prevention of delays in the project process. The findings show that the work plan created using BIM-based 3D and 4D modeling offers significant advantages in terms of time management, cost control, and material management. The study also examined the impact of BIM on material stock management in detail, determining that visualizing material storage areas on a 3D model on-site has made material logistics more systematic and controlled. In conclusion, the widespread use of BIM technology in construction projects offers more efficient and error-free management in planning processes. However, it is emphasized that factors such as training, regulatory adjustments, and industry adaptation need to be developed for BIM to be used effectively. The findings of this study reveal that BIM 3B and BIM 4B technologies should be applied more widely in construction projects. Keywords: Building Information Modeling (BIM), Project Management, Material Supply Planning, Inventory Management, MS Project, 4B Modeling
The mediating role of job satisfaction in the effect of green transformational leadership on intention to leave the job
No full textIntroduction The literature on leadership has evolved in accordance with changing global expectations over time and the significance of new leadership approaches which are based on environmental sustainability has increased day by day. Green transformational leaders, one of the results of this evolution, are different from other leadership approaches in terms of their role in motivating employees and increasing their environmental awareness by integrating their environmental sensitivities into the organizational culture.Methods This study, which aims to determine the mediating role of job satisfaction in the effect of green transformational leadership on intention to leave, was conducted with 391 people working in 4 and 5 star hotels in Antalya region. Data obtained by convenience sampling method was examined with Smart-PLS program. The study was shaped on the axis of structural equation modeling.Results The findings showed that green transformational leadership has a negative effect on intention to leave and job satisfaction plays a mediating role in this relationship. In addition, green transformational leaders were found to increase employees' job satisfaction, strengthen their commitment to the organization and reduce intention to leave.Discussion The study shows that green transformational leadership has an effective structure not only in terms of green and environmental concepts but also in terms of organizational behavior. According to the Social Exchange Theory, green transformational leadership is thought to shape the job satisfaction of employees by interacting with them in accordance with moral and organizational norms.The author(s) declare that no financial support was received for the research, authorship, and/or publication of this article