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    15771 research outputs found

    Ethnographie du travail radiophonique

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    Le travail dans une radio est une activité professionnelle qui possède trois caractéristiques définitoires. Il s'agit d'une activité tournée vers la réalisation d'une production –le programme, l’émission ou l’œuvre en direct ou enregistrés – à chaque fois unique bien qu’elle s’inscrive dans des routines nécessaires. Elle représente une organisation collective, à la fois succession de tâches et collaboration au moment de la diffusion ou de l’enregistrement. C’est une action que l’on dit « située », dans ses moments de direct notamment. Pour rendre compte de ces dimensions, on peut observer les actes de travail des personnels et des participants à l’élaboration et à la réalisation d’un programme. On peut également rendre compte du fonctionnement de la direction des programmes, de l’élaboration des sites internet des radios, de l’organisation générale de l’entreprise ou de l’association.Ces observations mobilisent plusieurs méthodes : l’entretien, l’analyse de documents, l’analyse de conversation, notamment à l’antenne, ou l’observation ethnographique.nonouirechercheNationa

    Epigenetic silencing of DKK3 in medulloblastoma

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    Medulloblastoma (MB) is a malignant pediatric brain tumor arising in the cerebellum consisting of four distinct subgroups: WNT, SHH, Group 3 and Group 4, which exhibit different molecular phenotypes. We studied the expression of Dickkopf (DKK) 1–4 family genes, inhibitors of the Wnt signaling cascade, in MB by screening 355 expression profiles derived from four independent datasets. Upregulation of DKK1, DKK2 and DKK4 mRNA was observed in the WNT subgroup, whereas DKK3 was downregulated in 80% MBs across subgroups with respect to the normal cerebellum (p < 0.001). Since copy number aberrations targeting the DKK3 locus (11p15.3) are rare events, we hypothesized that epigenetic factors could play a role in DKK3 regulation. Accordingly, we studied 77 miRNAs predicting to repress DKK3; however, no significant inverse correlation between miRNA/mRNA expression was observed. Moreover, the low methylation levels in the DKK3 promoters (median: 3%, 5% and 5% for promoter 1, 2 and 3, respectively) excluded the downregulation of gene expression by methylation. On the other hand, the treatment of MB cells with Trichostatin A (TSA), a potent inhibitor of histone deacetylases (HDAC), was able to restore both DKK3 mRNA and protein. In conclusion, DKK3 downregulation across all MB subgroups may be due to epigenetic mechanisms, in particular, through chromatin condensation.nonouirechercheInternationa

    Exception d’illégalité

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    nonouinon-rechercheNationa

    Introduction to the Special Issue:"Energy, Commodities and Geopolitics: Modeling Issues"

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    nonouirechercheInternationa

    Feasibility and individual rationality in two-person Bayesian games

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    We define feasible, posterior individually rational solutions for two-person Bayesian games with a single informed player. Such a solution can be achieved by direct signalling from the informed player and requires approval of both players after the signal has been sent. Without further assumptions on the Bayesian game, a solution does not necessarily exist. We show that, if the uninformed player has a “uniform punishment strategy” against the informed one, the existence of a solution follows from the existence of Nash equilibrium in infinitely repeated games with lack of information on one side. We also consider the extension of the result when both players have private information.nonnonrechercheInternationa

    Can Evoking Nature In Advertising mislead Consumers? the Power of ‘executional Greenwashing

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    ‘Executional greenwashing’ refers to the use of nature-evoking elements in dvertisements to artificially enhance a brand’s ecological image. Based on classic models of persuasion, a first experiment reveals that evoking nature does mislead consumers, especially if they have low knowledge of environmental issues in the product category. Two complimentary experiments, based on current international policies, show that whereas a raw figure featuring the product objective environmental performance is not sufficient to help non-expert consumers revise their judgment, accompanying the figure with a traffic-light label eliminates the ‘executional greenwashing’ effect amongst both experts and non-experts. Theoretical and regulatory implications are discussed.nonouirechercheInternationa

    Mauboussin Japon : Un joyau français en Asie

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    La différenciation est de manière courante le mantra de la stratégie marketing. Mais comment l'entreprise réagit-elle lorsque la segmentation de son périmètre de marché devient un ensemble flou, que la différenciation de ses produits et de sa marque perd de son attrait ; enfin, que la fréquence d'achat et la fidélité du consommateur appartiennent au passé ? Telle est la situation à laquelle le joailler de luxe de la place Vendôme se trouve confronté. Pourquoi et comment Mauboussin doit-il et peut-il tirer parti de sa marque emblématique pour accéder à de nouveaux clients, en France et à l'étranger, à travers de nouveaux canaux, tout en préservant l'image de ses produits de luxe, fondée sur le mythe de la rareté et de l'exclusivité ?nonouirechercheInternationa

    La sécurité patrimoniale du mineur et du majeur en tutelle

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    nonouirechercheNationa

    Guest Editorial: Mathematics and Image Analysis

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    This special issue highlights some recent developments in the field of mathematical image analysis. The emphasis of the issue is on the interplay between advanced mathematical methods (such as non-smooth optimization, variational methods and regularization, inverse problems, and partial differential equations) and their application to various problems in image processing and computer vision, including restoration, segmentation, and classification. The special issue comprises nine papers which cover a wide range of topics in mathematical image analysis as outlined below.nonouirechercheInternationa

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