Archives of the Faculty of Veterinary Medicine UFRGS
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Usability and Digital Accessibility for Older Adults: A Comparative Study between Moodle and Coursera
No full textThis study investigates the usability and accessibility of online learning platforms used by older adults through a comparative analysis of Moodle and Coursera. Eleven participants from the Open University for Senior Citizens (UNATI) performed structured tasks and answered questionnaires based on Nielsen’s heuristics and WCAG 2.0 guidelines, complemented by direct observation. Rather than merely comparing the platforms, this work validates a practical method for evaluating usability and accessibility, with a focus on older adults. The results indicate that, although both platforms received positive evaluations, Coursera presented significant barriers, such as navigation difficulties and inconsistent localization, whereas Moodle was perceived as more accessible and intuitive. The findings provide insights to support the development of more inclusive educational environments and the adoption of replicable assessment methodologies in diverse digital-learning contexts
Experimental Uveitis in Dogs : Comparison of Topical Ketorolac Tromethamine Versus Flurbiprofen
No full textBackground: Topical anti-inflammatory medication is the 1st choice to treat anterior uveitis, considered one of the most common eye disease in dogs. The inflammatory process must be controlled because when exacerbated it may cause pain, glaucoma, retinal degeneration and blindness. Among the topical non-steroidal anti-inflammatory drugs used in veterinary medicine, flurbiprofen and ketorolac tromethamine are highlighted. Flurbiprofen and ketorolac are important to treat uveitis, but ketorolac has not been widely studied in dogs. The aim of this study was to evaluate the effect of 0.5% ketorolac tromethamine versus 0.03% flurbiprofen in the dog’s eye submitted to experimental uveitis.
Materials, Methods and Results: The study was a crossover, descriptive and randomized clinical trial. Ten healthy adult (4 ± 3 years old) mongrel dogs (4 neutered male and 6 spayed female) were used and each dog received a double procedure (on the right and left eyes), using 2 different treatments, performed in a blind fashion. It was administrated 0.5% ketorolac tromethamine and 0.03% flurbiprofen, respectively, on the right and left eyes. Paracentesis of the anterior chamber was performed to induce uveitis on the right eye. An aliquot of 0.2 mL of the AH was collected at M0 and after 30 min (M1). At this time, one ketorolac drop was instilled, and another aliquot of 0.3 mL of the AH was collected 30 min later (M2). Five days later (washout), the same procedure was carried out on the left eye, followed by treatment with flurbiprofen. Aqueous humor samples were collected to measure the PGE2 concentration by competitive enzyme immunoassay, and to quantify ketorolac or flurbiprofen by High-performance liquid chromatography (HPLC) method. Ophthalmic examination and Intraocular Pressure (IOP) measurement using Goldmann tonometer were performed 12, 24, 36, 48 and 60 h after M2. All animals were treated with ketorolac and flurbiprofen eye drops (right and left eye respectively), 4 times daily up to 60 h. IOP was not significantly different from the baseline values. Mean levels of PGE2 decreased in both treated eyes without significant difference. HPLC showed that the concentration of flurbiprofen and ketorolac were also not significantly different.
Discussion: It is believed that IOP measurements of both treated eyes were not different from the basal values because the measurement was performed 8 h after the last paracentesis, when the treatments had already started. The time elapsed associated with the anti-inflammatory effect of both eye drops, therefore, may have been sufficient to restore the pressure after paracentesis and rupture of the blood-aqueous barrier. PGE2 level in the AH has been used to evaluate the effectiveness of anterior uveitis treatments. PGE2 decreases in the present study confirm that flurbiprofen and ketorolac were effective to control the inflammatory process induced by paracentesis. The anti-inflammatory effect of ketorolac tromethamine was probably attributed to satisfactory penetration in the anterior chamber. The results indicated that 0.5% ketorolac tromethamine had penetration and detectable concentrations in AH of dogs. Topically applied 0.5% ketorolac tromethamine was as effective as flurbiprofen to control ocular inflammation. Further studies are needed to consolidate the information on the pharmacokinetics and pharmacodynamics of this drug in dogs.
Keywords: topical anti-inflammatory drug, Blood-aqueous barrier, Aqueous humor, eye
Edital de submissão de artigos em fluxo contínuo
No full textEdital de submissão de artigos em fluxo contínu
Homenagem ao Prof. Nogueira Flores
No full textHomenagem realizada no Serviço de Cirurgia Infantil da Santa Casa de Misericórdia, em 30 de outubro de 1938, ao Prof. Nogueira Flores, catedrático de Clínica Pediátrica e Cirúrgica da Faculdade de Medicina da Universidade de Porto Alegre, pela turma de doutorandos de 1938, por ocasião da inauguração do seu retrato
Puede el constructivismo social en las RI dar forma a las políticas exteriores? : Un caso de las relaciones entre Corea del Norte y China
No full textFrom time to time, North Korea and China’s relations have been analyzed by different scholars as a byproduct or satellite state of China. We often debate power, war, and allies from a realist understanding. However, the constructivist approach has not been addressed much. The significant developments during the Korean War were symbolic, shared ideas, and the creation of identities, which were crucial to understanding the state’s choice and preference in foreign policy decision-making. In this article, I draw on the work of the constructivist approach to argue the North Korean and China relations during the Korean War. In this way, the constructivist explanation can be suitable for explaining the dynamics of North Korean and China ties because they look at the history and social dynamics within states for its outcome.De vez en cuando, las relaciones entre Corea del Norte y China han sido analizadas por diferentes estudiosos como un subproducto o un estado satélite de China. A menudo debatimos sobre el poder, la guerra y los aliados desde una comprensión realista. Sin embargo, el enfoque constructivista no ha sido abordado mucho. Los acontecimientos significativos durante la Guerra de Corea fueron simbólicos, ideas compartidas y la creación de identidades, que fueron cruciales para comprender la elección y la preferencia del Estado en la toma de decisiones de política exterior. En este artículo, me baso en el trabajo del enfoque constructivista para argumentar las relaciones entre Corea del Norte y China durante la Guerra de Corea. De esta manera, la explicación constructivista puede ser adecuada para explicar la dinámica de las relaciones entre Corea del Norte y China, ya que analiza la historia y la dinámica social dentro de los estados para su resultado
