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Variaciones transdisciplinarias del entretejer artístico
No full textThis research is based on the construction of a space for dialogue for the exchange of perceptive, sensitive and intellectual experiences in the context of a university course on the transdisciplinary nature of the art field. To develop this experience, a collaboration was carried out between a teacher and researcher with studies in art and interests in the epistemological conditions of the artistic, and a teacher and researcher with studies in philosophy and cinema and interests in artistic research. The interweaving of teaching and research itineraries generated an argumentative field of dialogue that fostered the transdisciplinary elasticity of the teaching task. On this basis, a methodology of transdisciplinary cooperation based on projects (MTCP) was proposed to the students with the intention of interweaving: a) cooperative learning, which tries to provide equal participation; b) transdisciplinary learning, which mobilizes the interaction between knowledge; and c) learning based on projects, which enables an extension beyond the classroom. To implement this method, three transdisciplinary variations were introduced: a) dialogue with people outside the field of art; b) establishment of alliances between people in the group; and c) joint conversation among all participants.; La presente investigación se basa en la construcción de un espacio de diálogo para el intercambio de experiencias perceptivas, sensibles e intelectuales en el contexto de una asignatura universitaria sobre el carácter transdisciplinar en el ámbito del arte. Para desarrollar esta experiencia, se realizó una colaboración entre un docente e investigador con estudios en arte e intereses en las condiciones epistemológicas de lo artístico, y un docente e investigador con estudios de filosofía y cine e intereses en la investigación artística. El entrecruzamiento de itinerarios docentes e investigadores generó un campo argumental de diálogo que abonó la elasticidad transdisciplinar de la tarea docente. Sobre esta base, se propuso al estudiantado una metodología de cooperaciones transdisciplinares basadas en proyectos (MCTP) con la intención de entretejer: a) el aprendizaje cooperativo, que trata de promover la participación igualitaria; b) el aprendizaje transdisciplinar, que moviliza la interacción entre saberes; y c) el aprendizaje basado en proyectos, que posibilita una extensión más allá del aula. Para implementar este método se introdujeron tres variaciones transdisciplinarias: a) diálogo con personas externas al ámbito del arte; b) trazado de alianzas entre las personas del grupo; y c) conversación conjunta de todos los participantes
Luis Romero Novella, El foro de Los Bañales de Uncastillo. Arquitectura y programas epigráficos, escultóricos y decorativos, Serie Monografía "Los Bañales", Fundación Uncastillo, Universidad de Navarra, 2023, pp. 526+430 (2 vol. Híbrido papel/digital), ISBN: 978-84-09-53855-3.
No full textSubastas. Un análisis económico
No full text218 pLas subastas y licitaciones se utilizan cada vez más para la asignación o compraventa de bienes, servicios, obras y suministros. El análisis económico de las subastas ha tenido bastante éxito explicando aspectos fundamentales del comportamiento de los agentes que participan en ellas. Este libro presenta esas explicaciones y las utiliza para justificar los tipos y características de las subastas que se realizan en un conjunto amplio de problemas de asignación y, también, para señalar qué errores pueden haberse cometido en el diseño de algunas subastas. En el libro no solo se consideran las subastas (y licitaciones) de un bien o servicio: se estudian también, entre otras, las subastas de múltiples unidades de un mismo bien, las subastas simultáneas y las subastas consecutivas de unidades de un mismo bien o de varios bienes y servicios heterogéneos y las subastas combinatorias
El arte en función del diseño de moda: Metodologías didácticas de experimentación
No full textThis article addresses the issues observed in the advanced degree program in fashion design at Hacer Creativo in Zaragoza, where students exhibited difficulties in developing designs grounded in research based on contemporary artistic references. This reflection is carried out through a Problem-Based Learning (PBL) approach, which introduces "objectophilia" as a conceptual foundation. Through an experimental theoretical-practical process, the challenges, benefits, and contradictions arising from the experimentation with the coexistence of art and functionality in design are analyzed. As a result of this project, the elective course "Art in Fashion Design" is created and implemented for the first time in the fourth year of the degree. Finally, it is proposed that fashion education should incorporate an approach based on the acquisition of procedural and conceptual tools to help structure designs, thereby fostering the creation of garments with greater aesthetic and even functional coherence.; Este artículo aborda la problemática observada en el grado superior de diseño de moda Hacer Creativo de Zaragoza, donde los estudiantes mostraban dificultades para desarrollar diseños fundamentados en una investigación basada en referentes artísticos contemporáneos. Esta reflexión se realiza a través de un ABP que plantea la 'objetofilia' como base conceptual. A través de un recorrido experimental teórico-práctico, se analizan qué dificultades, beneficios y contrariedades surgen de la experimentación en la coexistencia del arte y la funcionalidad en un diseño. A través de este proyecto se crea e implementa por primera vez la asignatura optativa "El arte en función del diseño" en el cuarto curso del grado. Finalmente se plantea que la educación en moda debe considerar un enfoque basado en la adquisición de herramientas procedimentales y conceptuales que ayuden a estructurar un diseño, y así favorecer la creación de prendas con mayor coherencia estética e incluso funcional
Developing non-isocyanate polyurethane chemistry for more sustainable structural composites in a circular economy.
No full text346 p.This doctoral thesis investigates polyhydroxyurethanes (PHUs) as a more sustainable alternative to conventional fossil-based polymer matrices used in natural fiber-reinforced composites (NFCs). PHUs are derived from CO2-based cyclic carbonates and polyamines, making them safer and greener. They offer strong hydrogen bonding with cellulosic fibers, improved recyclability through reversible reactions, and enhanced mechanical performance, showing a 20-30% improvement over traditional epoxy composites.To make PHUs suitable for industrial applications, a copolymerization strategy was developed that improved their processability and enabled their use in techniques like resin transfer molding (RTM). The resulting composites also exhibited self-healing properties and allowed for efficient fiber recovery, with natural fibers retaining their mechanical integrity after recycling.A life cycle assessment (LCA) confirmed the environmental advantages of PHU-based composites, supporting their potential role in sustainable materials development. However, further research is needed to fully align with the European Union's sustainability goals
Influence of 5-HTT, COMT, and BDNF functional polymorphisms and their interaction with parental bonding in attachment anxiety, among adults with personality disorders
No full textBackground and objectives
Attachment is the tendency of human beings to create strong affective bonds towards specific figures, and has been described as a general vulnerability factor to diverse forms of psychopathology. Although attachment research has not tended to emphasize genetic contribution, heritability is estimated at 36–45 %. We explored the association between 5-HTTLPR, COMT Val158Met and BDNF Val66Met functional polymorphisms with attachment dimensions, as well as the gene-environment interaction, considering the perceived parental rearing styles, with both a vulnerability and a differential susceptibility approach.
Methods
150 outpatients with a cluster B personality disorder participated in the study. Attachment was assessed using Experiences in Close Relationships-Revised and rearing styles by means of the Parental Bonding Instrument. Genotypes were analyzed using saliva samples. Statistical analyses were carried out with general linear models.
Results
COMT ValVal homozygotes and BDNF Met-carriers were associated with significantly higher scores in attachment anxiety (COMT: ValVal 4.95±1.25 vs Met-carriers 4.42±1.30, t=-2.096, p=0.038; BDNF: ValVal 4.38±1.31 vs Met-carriers 4.95±1.24, t = 2.833, p=0.005). From a differential susceptibility approach, plasticity genotypes were identified for the three functional polymorphisms, observing significant interactions with parental overprotection and differential outcomes in relation to attachment anxiety. No associations or interactions were found with regard to attachment avoidance and the care dimension.
Conclusion
Our results suggest that there are individuals more susceptible to rearing experiences in terms of adult attachment outcomes, which probably also implies a greater potential to benefit from environmental and psychotherapeutic interventions.The study was funded by the Health Department of the Basque Government under grant 2014111034. Edition was supported by the Research Unit of Galdakao-Usansolo Hospital. Open Access funding was provided by University of Basque Country UPV/EHU within the CRUE-CSIC Agreement
Proteomic profiling of extracellular vesicles in inflammatory bowel diseases
No full textThe proteomic analysis of serum extracellular vesicles (EVs) could be a useful tool for studying the pathophysiology of Crohn’s disease (CD) and ulcerative colitis (UC), as well as for biomarker discovery. To characterize the proteomic composition of serum EVs in patients with CD and UC to identify biomarkers and molecular pathways associated with pathogenesis and activity. Methods: Serum EVs were enriched and analyzed in patients with quiescent CD, active CD (aCD), quiescent UC, active UC (aUC), and healthy controls (HCs) (n = 30 per group). All groups were matched for age and sex. Disease activity was assessed by ileocolonoscopy and categorized based on the SES-CD (CD) and the endoscopic sub-score of the Mayo Score (UC). EVs were enriched by ul-tracentrifugation, and their size and concentration were determined by nanoparticle tracking analysis. The expression of CD63, CD81, and CD9 was determined using West-ern blotting. Proteomic analysis was performed by label-free nano-LC MS/MS. A total of 324 proteins were identified; 60 showed differential abundance in CD-HC, 34 in UC-HC, and 21 in CD-UC. Regarding disease activity, the abundance of 58 and 32 proteins was altered in aCD-HC and aUC-HC, respectively. Functional analyses revealed that proteins associated with aCD were involved in immune regulation, whereas those linked to aUC were enriched in oxidative stress. We have identified expressed proteins between EVs from patients with CD and UC, depending on the presence of disease, the disease type, and the disease activity. These proteins are potential candidates as disease biomarkers and open new research avenues to better understand these conditions.This research has been funded by grants from the Spanish Working Group on Crohn’s Disease and Ulcerative Colitis (GETECCU), XX (Beca GETECCU-Faes Farma), European Crohn’s and Colitis Organisation (ECCO), and Asociación Española de Gastroenterología (Beca Gonzalo Miño). D.B. is also a member of the CSIC’s Global Health Platform (PTI Salud Global)
OVIEDO SILVA, Daniel, El enemigo a las puertas. Porteros y prácticas acusatorias en Madrid (1936-1945), Comares, Granada, 2023, 340 pp.
No full textNaked-eye detection of Legionella pneumophila using smart fluorogenic polymers prepared as hydrophilic films, coatings, and electrospun nanofibers
No full textLegionella pneumophila is a significant public health threat, responsible for severe diseases such as Legionnaires’ disease. Traditional detection methods are often labour-intensive, time-consuming, and require sophisticated equipment. This study introduces smart fluorogenic polymeric materials for the naked-eye detection of L. pneumophila via protease activity. These materials, prepared as hydrophilic films, cellulose-coated linear copolymers, and electrospun nanofibers, operate on an OFF/ON FRET system, emitting fluorescence under UV light upon interaction with L. pneumophila proteases. Characterisation confirmed the successful immobilisation of the peptide substrate and its response to proteases. The sensors showed moderate to high sensitivity and specificity, with detection limits of 2.91 × 105, 3.64 × 10⁵, and 4.04 × 105 CFUs/mL for the film, copolymer, and nanofiber formats, respectively. Cross-reactivity tests identified only Pseudomonas aeruginosa as an interferent. This novel approach offers rapid, simple, and cost-effective L. pneumophila detection with visible results under UV light, suitable for clinical and environmental samples. It highlights the potential for broader pathogen detection applications.We gratefully acknowledge the financial support provided by all funders. The financial support provided by Fondo Europeo de Desarrollo Regional-European Regional Development Fund (FEDER, ERDF) and Regional Government of Castilla y León -Consejería de Educación, Junta de Castilla y León- (BU025P23) is gratefully acknowledged. This work was supported by the Regional Government of Castilla y León (Junta de Castilla y León) and the Ministry of Science and Innovation MICIN and the European Union NextGenerationEU PRTR. Author Saul Vallejos received grant BG22/00086 funded by the Spanish Ministerio de Universidades. Author Marta Guembe-García received funding from the Spanish Ministerio de Universidades-European Union under the framework of NextGeneration EU RD 289/2021 for her Post-Doc position. We also acknowledge the financial support provided by MCIN/AEI/ 10.13039/501100011033 and by “ERDF A way of making Europe” (grant PID2020-113264RB-I00). Edurne González acknowledge the financial support of the Spanish Ministerio de Ciencia e Innovación (Proyectos de I+D+i, grant PID2020-117628RJ-I00). Issei Otsuka acknowledges the financial support of the French National Centre for Scientific Research (Emergence International grant)