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Investigation into Knowledge and Adherence To Vaccination and Screening Campaigns among Immigrants in the Marche Region, Central Italy
Promoting preventive health through vaccination and screening is a key public health goal. Immigrant populations often show lower uptake compared to the general population, highlighting the need for targeted interventions. This study examines knowledge and adherence to vaccination and screening programs among immigrants residing in the Marche Region, Central Italy. To evaluate the socio-economic and cultural characteristics of immigrants, as well as their participation in vaccination and screening programs. A structured questionnaire was developed ad hoc. Data collection was conducted via assisted interviews with a convenience sample of immigrants in the Province of Pesaro-Urbino. The study sample was mostly female 59 (84.3%), with participants primarily from Ukraine 30 (42.9%) and Moldova 15 (21.4%). The average age was 53 years, and they had lived in Italy for 17 years on average. The majority of immigrants had a high school diploma or higher degree 56 (52.9%). Most immigrants 66 (96%) reported receiving all mandatory childhood vaccinations in their country of origin, however, vaccination coverage declined after migration to Italy. Although 89% of participants were aware of disease prevention through screening, only 27% had participated in screening programs in their country of origin, whereas, 71% had a cancer screening in Italy, primarily through public health invitations. Screening and vaccine hesitancy were mainly linked to lack of information or absence of invitations (76%), time constraints (14%), low trust in screening efficacy (7%). This study highlights the low adherence to vaccination programs among the immigrant population in Italy, emphasizing the need for policymakers and health authorities to design local level interventions to improve communication strategies, enhance healthcare accessibility and ultimately contribute to better health outcomes, cost savings, and more equitable healthcare systems
Parole nuove per com-prendere il Metodo Rondine. Lo sguardo della psicologia sociale.
Le esperienze vengono fatte e, poi, molto spesso vengono narrate. Quando vengono narrate acquisiscono significati innovativi e differenti, e acquisiscono un valore inedito anche quando vengono ascoltate e accolte in una mente nuova. Le esperienze possono generare sporgenze nuove anche quando vengono rilette alla luce di prospettive teoriche che possono portare sguardi e domande che consentono di “setacciare” e illuminare aspetti prima presenti, ma meno noti. Questo è quello che abbiamo cercato di fare quando, come psicologhe
sociali dei gruppi e della famiglia, ricercatrici e formate al Modello relazionale-simbolico di (v. Cigoli, Scabini, 2006; Scabini, Cigoli, 2000; 2012; Scabini, Iafrate, 2019), abbiamo incontrato l’esperienza di Rondine e lo sguardo visionario di Franco Vaccari. La riflessione, la ricerca e l’alta formazione scaturite da questo incontro negli ultimi dieci anni ci hanno consentito di rintracciare in Rondine delle parole chiave che rappresentano degli snodi cruciali su cui l’esperienza di Rondine ruota e che sono delle sorgive di generatività. Proviamo a sintetizzarli
Le tracce del tempo: paesaggi e testimonianze archeologiche. Omaggio a Umberto Moscatelli
Anfiteatro, Pisaurum, topografia, Marche, Pesar
Search for Continuous Gravitational Waves from Known Pulsars in the First Part of the Fourth LIGO-Virgo-KAGRA Observing Run
Continuous gravitational waves (CWs) emission from neutron stars carries information about their internal structure and equation of state, and it can provide tests of general relativity. We present a search for CWs from a set of 45 known pulsars in the first part of the fourth LIGO–Virgo–KAGRA observing run, known as O4a. We conducted a targeted search for each pulsar using three independent analysis methods considering single-harmonic and dual-harmonic emission models. We find no evidence of a CW signal in O4a data for both models and set upper limits on the signal amplitude and on the ellipticity, which quantifies the asymmetry in the neutron star mass distribution. For the single-harmonic emission model, 29 targets have the upper limit on the amplitude below the theoretical spin-down limit. The lowest upper limit on the amplitude is 6.4 × 10−27 for the young energetic pulsar J0537−6910, while the lowest constraint on the ellipticity is 8.8 × 10−9 for the bright nearby millisecond pulsar J0437−4715. Additionally, for a subset of 16 targets, we performed a narrowband search that is more robust regarding the emission model, with no evidence of a signal. We also found no evidence of nonstandard polarizations as predicted by the Brans–Dicke theory
Shallow Lakes and Loading Constraints: A Normative Approach
The economic-ecological system of shallow lakes is characterized by nonlinearity and
hysteresis. A Pigouvian tax is traditionally used to reconcile stakeholders’ interests, but it
does not guarantee an oligotrophic state of the lake. A different approach to pollution control is that of quantitative regulation. In our model, an environmental authority introduces
a cap on the growth rate of phosphorus stock to save the lake. We get three main results.
First, the adoption of a quantity constraint affects stakeholders’ decisions not only when it
is binding but even when it is still slack. Indeed, the community finds it optimal to anticipate the effect of the latent constraint at the beginning of the planning horizon. As a result,
phosphorus loading may even increase in intermediate periods, before the constraint binds.
Second, our model shows that an optimal management path emerges in the intermediate
stages, and the cap can drive the shallow lake toward the oligotrophic state. Finally, results
crucially depend on the fine-tuning of the constraint. If initial conditions allow, the saddle
path converging to the oligotrophic steady state can be approached. Therefore, moderate
policy changes have long-term effects on the health of the lake
COLOSTRUM AND MILK EVS FROM WATER BUFFALO SAMPLES: PRELIMINARY CHARACTERIZATION AND EVALUATION OF THEIR EFFECTS ON BOVINE MACROPHAGES AND HUMAN INTESTINAL CELLS
Colostrum and milk are nutrient-rich liquids produced by mammals, beyond traditional nutritional aspects, recent research has focused on extracellular vesicles (EVs) and their potential health benefits, especially for gastrointestinal health. This study aims to characterize and evaluate the effects of EVs from colostrum and milk of water buffaloes, on bovine macrophages and human intestinal cells. Briefly, 15 and 60 days milk (15m and 60m) and colostrum (colo) from water buffaloes (Bubalus bubalis) were obtained by Istituto Zooprofilattico Sperimentale del Mezzogiorno and after centrifugation steps, serum samples were shipped to laboratory of University of Urbino for the characterization of EVs. The samples were filtered (450 nm) and labelled by LCD, anti-CD63, anti-CD81 and anti-CD9. Two different clones of anti-human -CD9 antibody (M-L13 and MM2-57) were screened for cross reactivity with buffalo species. The MM2-57, known as cross reactive with bovine, was the only one that showed cross reactivity with buffalo leukocytes. Furthermore, EVs from utracentrifugation of selected colo, 15m and 60m samples, were analysed by means of NTA, FC and Transmission Electron Microscopy (TEM) and employed for conditioning (4 and 24h) both BOMAC bovine macrophages and Caco-2 human intestinal cells. Uptake experiments through PKH67 labelled EVs, highlights a greater internalization for colostrum EVs, at both investigated time-points (4h and 24h), indeed only colo EVs demonstrated to moderately increase the scarce phagocytic activity of BoMAC cells (Barletta RG, et al. 2023; Woo, S. R., et al.2006). On water buffalo macrophages, colo EVs lowered FITC-labelled E coli cell adhesion. On the contrary, all the studied EVs revealed to modulate basal mitochondrial ROS production, particularly after 24h. Intriguingly, at the same time point, the
lysosome compartment is reduced by colo EV addition (with the highest uptake) and also by 60m EV addition, characterised by mild uptake, suggesting a different EV cargo. In human intestinal Caco-2 cells, our preliminary data highlight a more pronounced uptake, and EV treatment leads to a decrease in basal hydrogen peroxide, particularly after 4h. These preliminary findings underscore the promising role of colostrum and milk-derived EVs in supporting human gastrointestinal health and different functions in bovine and bubaline cells. Further experiments are ongoing to confirm and extend the above mentioned results. This research was funded by the Italian Ministry for Health (grant number RC IZSME 03/23 RC)
Titian's Mythological Paintings: A Pictorial Personal Code
This paper aims to introduce pictorial personal codes that differ from linguistic ones. Since individual norms distinguish personal codes, the concept of norms serves as the starting point for extending their scope beyond language. Indeed, there is a strong case for nonverbal norms within the philosophy of normativity. Gestures and drawings can establish these nonverbal norms. Drawn norms, such as those enforced by traffic signals, are part of a pictorial code in our everyday experiences. However, the application of this code view has been challenged in the field of semiotics, particularly in art and visual semiotics. Conversely, the pictorial turn suggests that cultural history involves a struggle between words and pictures. Pictures differ from words, yet are not purely visual media. This distinction can be traced back to Marcello Barbieri's differentiation between the world of perceptual objects and the world of names. I hypothesize that pictorial personal codes lack an abstract system of rules but still present a set of norms that can be categorized into shared and individual. I exemplify this with a case study of the Venetian painter Tiziano Vecellio (Titian). By integrating research results from art history, I show that Titian transformed his workshop into a modern firm and, as a form of legitimization, defined his original style in terms of tragic painting, specifically a personal approach to painting that connotes a literary genre such as Greek tragedy. I also evaluate the role of a graphic code in Titian's productive system. Finally, I draw certain conclusions regarding the social ontology of the firm, suggesting that Titian's tragic painting illustrates how firms endure, thanks to personal or brand-specific codes, and propose that gestural personal codes, like pictorial ones and unlike linguistic ones, should include unsystematic legisigns and a set of norms that can be divided into shared and individual ones
L’intelligenza artificiale generativa e il gioco dell’imitazione
This paper discusses the recent experiments by Jones
and Bergen that showed ChatGPT-4 passed the Turing
test. To this end, the game proposed by Turing is placed
in the proper philosophical dimension by showing how it
tries to answer a well-formulated and circumscribed
question. The details of the experiment are then
investigated. Finally, some important consequences are
drawn regarding the problem of explainability of neural
networks