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Drivers of seedling emergence and early growth of 12 European oak species: Results from a cross-continental experiment
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From Loulon to the Fortress of the Black Camel. The routes of the Arab incursions in Cappadocia
No full textThe aim of this chapter is to try to identify the itineraries followed by Arab armies when entering Cappadocia during their incursions across the Anatolian plateau between the 7th and the 10th centuries AD. The analysis of the distribution of a series of ‘territorial markers’ and of itinerary information recoverable from the Arabic sources led to the detection of those routes and to a better understanding of the Arab military strategies in central Anatolia, as well as of the continuity/discontinuity of the post-Classical Cappadocian Road network; more specifically, the Graeco-Roman system of communication. In particular, it is argued that routes which were only of secondary importance during the Roman period acquired a new relevance starting from the end of the 7th century and, similarly, that main routes became less utilised, illustrating a clear shift in the organisation and exploitation of the landscape. Recent palaeoecological analysis of annually laminated sediments from Lake Nar have made it possible to reconstruct the changes that occurred within the Cappadocian landscape, confirming the hypothesis proposed on the basis of archaeological and topographical data
Trans-splenic anterograde coil-assisted transvenous occlusion (TACATO) of bleeding gastric varices associated with gastrorenal shunts in cirrhosis
No full textBackground & Aims: There is a lack of consensus on the optimal management of fundal gastric varices (GVs) in patients with cirrhosis due to varied anatomy and hemodynamics. In this study, we evaluate the safety and efficacy of trans-splenic anterograde coil-assisted transvenous occlusion (TACATO) for preventing recurrent bleeding in fundal GVs associated with gastrorenal shunt (GRS). Methods: In this 4-year study, patients with cirrhosis with GRS-associated GV bleeding, without prior esophageal variceal bleeding, ascites, or portal vein thrombosis, were eligible for TACATO. Trans-splenic access was achieved by puncturing a splenic venous branch using ultrasound/fluoroscopic guidance. A microcatheter was inserted into the varices for embolization with detachable microcoils and possibly N-butyl-cyanoacrylate-Lipiodol. Technical success was assessed by venography. All patients underwent follow-up endoscopy and decompensating events were recorded. A retrospective external control group of ..
DOMES: A general optimization method for the integrated design of energy conversion, storage and networks in multi-energy systems
Full text linkA realistic pursuit of decarbonization targets requires planning and designing new configurations of “multi-energy systems” to identify the optimal number, type, location and size of the energy conversion and storage units and their interconnections with the end users of different forms of energy. The common approach in the literature is to treat the optimization problem of energy conversion and storage separately from that of energy networks, and the few attempts to address the two problems simultaneously have led to oversimplifications due to the very large number of decision variables involved. To fill this gap, this study introduces “DOMES” (Design Of Multi-Energy Systems), a general optimization method for the integrated synthesis, design and operation of a multi-energy system in its entirety. With the goal of minimizing costs and reducing carbon emissions, DOMES can simultaneously find the location, type, size and operation of the energy conversion and storage units, as well as t..
Platinum(II) triphenylphosphane and triphenylarsane complexes help overcome resistance against cisplatinum resistant cancer cell lines
Full text linkIn the field of anticancer metal complexes many efforts are continuously devoted to overcome resistance phenomena. Within thousands of new complexes proposed each year as potential metallodrugs, compounds showing modes of action other than that of cisplatin appear promising. This minireview reports about the class of triphenylphosphane complexes of platinum(II), describing their synthesis, antiproliferative properties and modes of action, with a special focus on the possibility of overcoming resistance phenomena
Come nasce un classico. Sulla fortuna del teatro di Carlo Goldoni tra Sette e Ottocento
No full textDavvero si può continuare a credere – come è stato autorevolmente affermato da una longeva tradizione critica – che tra la fine del Settecento e i primi decenni dell’Ottocento l’eclissi del teatro goldoniano fu quasi totale?
L’analisi di fonti archivistiche già note (ma non sufficientemente meditate) o affatto inedite, lo spoglio della fiorente pubblicistica di interesse teatrale, il reperimento di stampe-copioni impiegate da compagnie ottocentesche e la ricostruzione delle loro fisionomie, ci rivelano in realtà un panorama decisamente diverso. Un panorama in cui si stagliano da un lato – dall’alto – le voci dell’intellighenzia teatrale, che all’unisono intonano il lamento della perdita, esprimendo in termini traumatici un vero e proprio “complesso dell’abbandono”, dall’altro – dal basso – gli operatori del mercato (e il versante teatrale intrattiene con quello editoriale legami di sintomatica specularità) che altrettanto concordemente attribuiscono all’opera goldoniana il valore di un titolo stabilmente quotato.
A monte del fenomeno, si intravede distintamente una pratica della scena che seppe, del testo goldoniano, illustrare le sotterranee risorse spettacolari, anche attraverso la sua manipolazione – o, per meglio dire, la scoperta della sua costitutiva flessibilità; e si deve riconoscere all’apparente ossimoro di un’esemplarità flessibile la possibilità di permanere in un contesto spettacolare tanto alieno dalla fissità.
Precisamente in questo potrebbero ravvisarsi i termini del paradossale “classicismo” con cui si espresse la frequentazione attoriale dell’opera goldoniana nell’Italia ottocentesca: proprio nella proliferazione di risposte possibili, da essa sollecitate, sembrerebbe essersi definita la nascita e la versatile “identità” di un classico
Automatic Segmentation of Quadriceps Femoris Cross-Sectional Area in Ultrasound Images: Development and Validation of Convolutional Neural Networks in People With Anterior Cruciate Ligament Injury and Surgery
No full textObjective: Deep learning approaches such as DeepACSA enable automated segmentation of muscle ultrasound cross-sectional area (CSA). Although they provide fast and accurate results, most are developed using data from healthy populations. The changes in muscle size and quality following anterior cruciate ligament (ACL) injury challenges the validity of these automated approaches in the ACL population. Quadriceps muscle CSA is an important outcome following ACL injury; therefore, our aim was to validate DeepACSA, a convolutional neural network (CNN) approach for ACL injury. Methods: Quadriceps panoramic CSA ultrasound images (vastus lateralis [VL] n = 430, rectus femoris [RF] n = 349, and vastus medialis [VM] n = 723) from 124 participants with an ACL injury (age 22.8 ± 7.9 y, 61 females) were used to train CNN models. For VL and RF, combined models included extra images from healthy participants (n = 153, age 38.2, range 13–78) that the DeepACSA was developed from. All models were tested on unseen external validation images (n = 100) from ACL-injured participants. Model predicted CSA results were compared to manual segmentation results. Results: All models showed good comparability (ICC > 0.81, 0.94, < 7.40% standard error of measurement, mean differences of <0.57 cm2). Erroneous predictions were 17% for combined VL, 11% for combined RF, and 20% for ACL-only VM models. Conclusion: The new CNN models provided can be used in ACL-injured populations to measure CSA of VL, RF, and VM muscles automatically. The models yield high comparability to manual segmentation results and reduce the burden of manual segmentation
JWST photometry and astrometry of 47 Tucanæ: Discontinuity in the stellar sequence at the star-brown dwarf transition
No full textUsing JWST Near Infrared Camera (NIRCam) images of the globular cluster 47 Tucanæ (or NGC 104), taken at two epochs just 7 months apart, we derived proper-motion membership down to mF322W2 ∼ 27. We identified an intriguing feature at the very low-mass end of the main sequence, around ∼0.08 M, at magnitudes mF322W2 ∼ 24 and mF150W2 ∼ 25. This feature, dubbed 'kink', is characterized by a prominent discontinuity in the slope of the main sequence. A similar discontinuity is seen in theoretical isochrones with oxygen-poor chemistries, related to the rapid onset of CH4 absorption. We therefore hypothesize that the cluster hosts disproportionately more oxygen-poor stars near the bottom of the main sequence compared to the upper main sequence and the red giant branch. Our results show no strong or conclusive evidence of a rise in the brown dwarf luminosity function at faint magnitudes, in contrast to previous findings likely affected by faint red background galaxies. In our analysis, we accounted for this contamination by using proper motion membership