Rajesh Varma
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Effect of tryptophan and glutamic acid on morphological traits of Iranian and Afghan saffron
No full textIn order to investigate the effect of amino acids tryptophan and glutamic acid on the morphological traits of the saffron medicinal plant, a factorial experiment was conducted in the form of a randomized complete block design in three replications in 2018 in the research farm of Zanjan University. The experimental treatments include three genotypes (Iranian, Afghani 1, and Afghani 2) as the main treatment and tryptophan amino acid at two levels (1 and 2 mM) and glutamic acid at two levels (1 and 2 mM) as secondary treatments. They were considered as testify. The results showed that tryptophan and glutamic acid treatments had a significant effect (p ≤ 0.01) on most of the studied traits including the number of flowers, dry weight of flowers, and vegetative body. The highest content of the number of flowers and dry weight of flowers were observed, respectively, 34.6 and 37.36 mg of dry weight. Also, the performance characteristics of the fresh weight of the flower and the dry weight of the stigma showed a significant difference (p ≤ 0.05) under the treatment of two amino acids. In total, different levels of tryptophan and glutamic acid can have an effective role in improving the morphological traits and production of this product. The use of 1 mM glutamic acid to produce the maximum vegetative body of the plant, the treatment of 1 and 2 mM of both amino acids to improve morphological indicators, and 1 mM of glutamic acid for the performance of secondary metabolites is desirable and recommended for the purpose.</p
Stamps as a cultural value related to the biodiversity of insects
No full textBiodiversity has been studied by many specialists and is the same as the terminology “biological diversity” with more than 1.8 million species with Latin name (Scientific name). The insects as a big group have between 751.000 to 950.000 species [1]. Recently, with molecular characterization, some groups get a different point of view [2-4].</p
The quality of medical and social expertise of the contingent of children with disabilities in the City Children’s Polyclinic
No full textThe quality control of the provision of the State Service of passing the Medical and Social Examination (SS MSE) is carried out as part of the implementation of a set of measures to achieve the indicators of the Decree of the President of the Russian Federation (RF) No. 601 (assessment of the level of satisfaction of citizens with the quality of state services). The purpose of the study was to determine the quality of the provision of SS MSE and possible reserves for its improvement. The analysis of 566 referrals for the passage of the SS MSE of a medical organization, submitted by official representatives of children - patients of the state budgetary healthcare institution of the Republic of Komi “Syktyvkar Children’s Clinic No. 3”, and a survey of official representatives of children who were diagnosed with disability, according to the questionnaire for assessing the level of satisfaction of citizens with the quality of the provision of SS MSE. Methods of analysis included: analytical and comparison. The following techniques were used for the analysis: grouping, absolute and relative values, average values, detailing, and generalization. The reliability of the results obtained was assessed by calculating the Student’s coefficients. The depth of the study was 3 years. Experts now have the opportunity to determine disability for children with severe persistent pathology not for 1 - 2 years, but for 10 - 15 years, in some cases, according to indications, and more, up to the age of 18. Some children and adolescents are permanently disabled. This significantly reduces the annual burden for patients to undergo examinations by medical specialists, and many clinical diagnostic and laboratory tests. At the same time, an annual examination by specialists of medical and social expertise to correct the individual rehabilitation/habilitation program of patients is not excluded.</p
COVID-19 diseases, understanding and treatments
No full textSeobuk Hospital is a hospital directly operated by the Seoul Metropolitan Government and has mainly served as a tuberculosis hospital. It is a Seoul city governmental public hospital which primarily provides inpatients and out patients treatment to the elderly, many of them suffering from dementia patients and the marginalized, such as the homeless and the disabled. From March 2nd, 2020, to May 31th, 2022 Seobuk hospital was appointed to treat COVID-19 patients that required stationary treatment. South Korea’s COVID-19 mortality rate has below 0.1% while in other countries such as the United States and in Europe the mortality rate varies between 1 and 2 %. We believe that it is due to the quarantine system which was put in place right from the start of the COVID-19 pandemic in Febuary 2020. Patients testing positive for COVID-19 were hospitalized free of charge and they were hospitalized usually in early period (2 - 3 days after COVID -19 testing) of COVID-19 disease. In this paper we analyzed the disease patterns of patients hospitalized with COVID-19 using the data from the 4,531 patients charts which received treatment in Seobuk hospital between March 2nd, 2020 and May 31st, 2022 by looking at their clinical features and medication history and medications for treatment. The key element of the guideline of our treatment was to administer Veklury (Remdesivir) or Paxlovid despite its high cost in the early period of the COVID-19 disease when oxygen saturation dropped below 94%. Nowadays we administer Veklury and Paxlovid right after COVID-19 is daignosed free of charge for the proper patient. It is believed that the current quarantine system in South Korea which allows patients to be treated with Veklury (Remdesivir) in hospitals at the initial stage of the infection and with an early Paxlovid administration in home treatment has contributed to lowering the death rate in South Korea. </p
Biological toxicity evaluation of traditional medicine white tea extract liquid
No full textPurpose: The aim of this study was to evaluate the safety and toxicity of intravenous use of White Tea Extract Liquid (WT) in rabbits through routine blood tests and biochemical and histopathological means. Design and methods: This study used the WT product produced by the company and the New Zealand rabbits at 2.0~2.5 kg of weight. Rabbits were divided into two groups: Control and WT groups. In the WT group, the diluted WT injection volume needed to be injected was calculated according to their body weight on days 1, 4, 7 and 11...... for 4 weeks respectively. During the1, 2 and 4 weeks of the experiment, blood routine, blood biochemistry and the histopathological sections of the heart, spleen, lung, trachea, kidney, bladder, uterus, testicle, stomach, liver, small intestine, big intestine were evaluated in the study. Findings: By comparison, the blood routine test did not deviate from the normal ranges provided by the diagnostic laboratory. The blood biochemical indexes of all experimental rabbits are within a reasonable range and did not detect clinically significant abnormalities between treatment and control groups. The WT had no obvious inflammatory change in the whole tissue and no harmful effect on the organs of various systems of the rabbits’ system for 4 weeks.Conclusions: After intravenous injection for 4 weeks in rabbits, white tea herb atomization liquid did not produce obvious toxic effects on the animals.</p
The association with histopathological findings and predictive significance of transforming growth factor beta 1 (TGF β1) in patients with chronic viral hepatitis
No full textBackground: Chronic Viral Hepatitis (CVH) is the most common cause of hepatocellular cancer and cirrhosis related to liver fibrosis. The gold standard in the diagnosis of fibrosis is liver biopsy. TGF β1 is a pleiotropic cytokine that plays a pivotal role in carcinogenesis and fibrosis. The results of studies investigating the relationship between TGF β1 and histopathological findings are controversial. We aimed to investigate the relationship between TGF β1 and histopathological findings.Methods: Patients with Chronic Hepatitis B (CHB) and C (CHC), Non-Alcoholic Steatohepatitis (NASH), inactive HBsAg carriers, patients with cirrhosis and healthy control cases presenting to the Gastroenterology Clinic of Sisli Etfal Training and Research Hospital between 2009-2010 were included in the study. Laboratory tests, HCV RNA, HBV DNA, viral load, and viral markers (such as HBsAg, anti-HCV) were determined. Biopsies were performed on patients with hepatitis B and C, and non-alcoholic steatohepatitis (NASH). Histologic features were defined as Histologic Activity Index (HAI) and fibrosis stage (Knodell’s scoring). TGF β1 was evaluated by the ELISA method. Results: 267 cases including 44 non-alcoholic steatohepatitis cases [27 female (57%)], 38 inactive HBsAg carriers [23 female (60%)], 48 patients with chronic hepatitis B [17 female (35%)], 27 chronic hepatitis C [14 female (60%)], 15 decompensated cirrhosis [3 female (20%)] and 94 healthy control cases were included in the study. Compared with healthy controls, all other subgroups had significantly elevated TGF β1 levels. TGF β1 was found to have a specificity of 93.6% and a sensitivity of 88.9% (AUC: 0.948, 95% CI: 0.916-0.981) in determining liver diseases. TGF β1 had a positive correlation with fibrosis and histological activity index in patients with CHB and CHC. There was a negative correlation between TGF β1 and HBV DNA and HCV RNA. TGF β1 had a significant correlation with LDL and total cholesterol in cases with CHB and CHC.Conclusion: TGF β1 is correlated with both HAI and fibrosis in patients with CHB and CHC. TGF β1 might have a role in the prognostic significance of elevated LDL levels and low viral load in patients with CHC. </p
Comparative advantage of improved feed trough and the traditional feeding material for efficient utilization of crop residue at small-scale farmers in Northwestern Tigray, Ethiopia
No full textThe study was conducted to reduce the high feed wastage by practicing the improved feed trough in the study area. The trail was conducted at Tahtay Koraro district Northwestern zone of Tigray, Ethiopia. Improved feed trough was constructed on a total of 20 interested farmers. Both quantitative and qualitative data were collected andanalyzed using descriptive statistics. The result showed that the improved feed troughs reduced feed waste significantly in the study area. That is 4.13% and 25% feed loss respectively in improved and traditional feed troughs. The result from the farmers perception also shows that, the farmers were preferred the technology in its less feed wastage, reduces feed contamination, gives an opportunity for persons to do other task than keeping animals, comfortable for the animals, reduces feed competition among the animals; and protects the feed from rain and sun. But farmers are less preferred the technology in its cost for its construction. Therefore, based on the result it is recommended that the technology has to be popularized and promoted to the large number of the farmers of the area for the efficient crop residue utilization. </p
A Review of side effects of Kombucha
No full textKombucha is a mushroom fermented in sweetened black or green tea, originally found in Asia, being used as a remedy for many ailments in this region. Kombucha is not a usual mushroom because it represents the symbiosis between yeast and a variety of bacteria aggregated through a permeable membrane. Among the benefits of Kombucha tea are the potential antioxidant effect against free radicals, and the clinical effects on diabetes for its hypoglycemic, lipid-lowering, and immune stimulation. But secondary to the lack of evidence to support these benefits, several publications emerged to mention the side effects of Kombucha consumption. The present article is trying to collect the data reported in the literature regarding the side effects of Kombucha. </p
Examination of hydrodynamic behavior of wind deflectors in the normal inner temperature with the point of more efficiency<br> <em>(Case study: Bwhsa Köppen climate classification of Kashan City)</em>
No full textOne of the ways to achieve a building with higher energy efficiency and an efficient system is to use local architectural experiences. In the meantime, a wind deflector is one of the elements used in the past to create comfort. In the Bwhsa Köppen climate classification of Kashan City, they used to move and cool the air in the building. This study investigates the interior of these settlements in this climate to aim to reach greater efficiency of this element by CFD software, Energy Plus, and Open Studio with a descriptive-analytical method and then analyzes the results. A comparison of the results of the analysis of wind speed in wind turbines and how the wind is oriented in the interior is shown. Due to the low thermal mass of the wind deflector walls compared to the room, the temperature fluctuation is always higher than in the room. The main factors in temperature drop are proportionality of dimensions-air inlet valve to the windshield, water temperature, measurements, and height of the windshield column. Finally, to reduce the room temperature further, the priority is to use a spray windshield over windshield wipers. Especially windshields with water spray in which most of the room has a temperature of 25 degrees Celsius and are in Kashan city’s thermal comfort range.</p
Surgical correction of omphalocele in local goat breed (Beetal) of Jhang, Punjab: A case study
No full textOmphalocele is a rare congenital condition where closure defects in the abdominal wall at the umbilical ring lead to the protrusion of intestinal or other visceral organs, covered by a thin epithelial layer. The developmental mechanism of this condition is not fully understood, and various theories have been proposed to explain it. This study presents a case of omphalocele in a newborn female black goat kid, detailing its clinical presentation, surgical management, and postoperative care. The surgical procedure involved meticulous preparation of the surgical site, administration of local anesthesia, and careful repositioning of the intestines, liver, and a portion of the spleen. Excess skin and the amnion membrane were removed to facilitate safe repositioning, and the umbilical ring was excised to widen the opening. The abdominal wall layers were meticulously closed using appropriate suture materials. The kid’s postoperative recovery was uneventful, with normal vital signs, fecal passage, and feeding behavior observed. The study discusses omphalocele in comparison to other abdominal abnormalities and explores potential developmental mechanisms. The authors emphasize the importance of immediate surgical intervention despite varying prognoses associated with this condition. The study underscores the significance of surgical treatment for omphalocele cases in newborn goat kids, providing hope for affected animals and valuable insights for veterinary professionals. Although the exact prevalence of omphalocele remains uncertain due to unreported cases, this report demonstrates successful surgical correction and the potential for curing the condition if diagnosed and treated promptly. Further research is needed to fully understand the genetic and environmental factors contributing to omphalocele and its impact on livestock.</p