Rajesh Varma
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5017 research outputs found
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Informatization process of wind and solar resource power generation: Empirical abstraction and packing algorithm
No full textThe development of software tools is critical to meeting the changing needs of the wind and solar resource generation industries. By identifying some of the limitations of existing systems, such as fragmentation in data query and plant management, as well as a lack of data resource management. In response to these issues, it is proposed to use a hybrid deep network model for simulation data to develop a management platform for wind and solar resource observation data. High-quality real-time measurement data and standardized data processing can be collected stably using these tools, which can significantly improve the development efficiency of landscape resource power generation projects and save development costs.</p
Promoting data element circulation for urban digital economy development
No full textData element circulation, also known as data circulation, refers to the entire process of continuously collecting, processing, storing, transmitting, and using data in economic and social activities. The rapid development of information technology has made the data elements circulation an important driving force for promoting economic growth, improving production efficiency, and fostering social innovation. However, the data elements circulation also presents a series of challenges, including data value, data security, data quality, data openness, and sharing. To fully unleash the value of data resources, improve the new foundational system, stimulate market vitality, and create a data element market with significant influence, this paper conducts a thematic study on promoting data element circulation. The significance of accelerating data element circulation, the global efforts in data element circulation, and the basic requirements for data element circulation are discussed. The paper also provides recommendations for promoting data element circulation, including policy and regulatory development, infrastructure enhancement, and continuous technological innovation. Furthermore, the paper emphasizes the importance of strengthening application scenarios, such as smart city initiatives and data center services and building a robust support system for data element circulation. The proposed strategies aim to foster high-quality development of the urban digital economy and facilitate the circulation of data elements.</p
Omega-3/omega-6 fatty acids: The effects on the psychophysical well-being of adolescents and adults
No full textBackground: Fatty acids of the omega-3/omega-6 groups are used especially in cases of pregnancy, lactation, and malnutrition. In recent decades, pediatrics has been trying to find out whether the use of omega-3/omega-6 has effects on human growth and neurodevelopment.Aims: Check the state of the art on the use of omega-3/omega-6 type fatty acids in the diet, in adolescent and adult populations.Materials and methods: A total of 72 original articles on the topic of human growth and nutrition in pediatrics have been selected on PubMed through September 2022.Results: In literature, the use of omega-3/omega-6, with greater prevalence in the former group than the latter group, appears to be most effective in hypertension hypothesis, dyslipidemia, and high C-reactive protein values, cardiovascular risk, and neuropathic pain, while appearing to have less impact on neurodegenerative (except in multiple sclerosis) and mental disorders (except in depression). Interesting benefits can be detected when combining omega-3/omega-6 with spirulina algae, chitosan, probiotics, vitamin D, fiber and plant extracts. Conclusion: Significant evidence emerges on the importance of omega-3 and omega-6 fatty acid supplementation, but important structural shortcomings of research designs still emerge from the published studies; moreover, many studies assume that fatty acid supplementation can have a curative effect on already active diseases, when in fact such prescriptions should be considered as adjuvant therapies to prevent or promote symptomatic regression, precisely because of their anti-inflammatory, antioxidant and immunomodulating virtues. However, there is no concrete and robust evidence of the positive impact on psychological well-being. Future research that can resolve the critical issues highlighted is hoped to promote a better approach to the topic of omega-3/omega-6 supplementation in human health.</p
Alopecia areata
No full textAlopecia areata, which is a condition with characteristic regional hair loss on the top of the head, is quite common in outpatient departments and clinics. The hair loss is rather rapid during the acute phase and the development into a severe form of alopecia may be related to the younger onset, along with nail changes, family history of atopic dermatitis, allergic rhinitis, asthmatic bronchitis, etc., or other autoimmune diseases. Physically, a large area of hair loss can be observed, as well as other typical features, including broken hair roots and exclamation mark hairs. The classic histopathological sign is the infiltration of lymphocytes around the hair follicles. Moreover, alopecia is not limited to the scalp, and hairs on any part of the body are subjected to the effect of this disease. </p
Nanozyme catalytic mimetic effect of iron oxide nanoparticles hybrids with cellulosic matrices and its synergism with microorganisms
No full textIron Oxide Nanoparticles (IONPs) are generally assumed to be biologically inert, presenting chemical stability and low toxicity, and they can be hybridized with cellulosic matrixes aiming for biological applications (e.g. nanozymes). Two hydrothermal coprecipitation methods were applied, aiming to produce 2 different size Iron oxide nanoclusters, using ferric chloride and ferrous chloride, as well as nitrocellulose and cellulosic residues for the hybrids. The obtained materials were tested for catalytic effect in comparison and in synergy with catalase-positive P. aeruginosa, S. aureus, and B. subtilis bacterial strains. The catalytic effect was observed for all obtained materials and microorganisms, Due to the bivalent and trivalent iron molecules distributed along IONP cubic crystalline inverse spinel structures. Michaelis-Menten constant (Km) of IONP-and hybrids was higher in synergy with S. aureus in comparison with the results obtained by the microorganism alone, for instance, the best enzymatic efficiency for O2 release from hydrogen peroxide among the tested microorganisms. However, no significant difference was observed for most of the obtained materials alone. On the other hand, IONPs may help microorganisms as mimetic catalytic enzymes, when applied in synergy whit them. </p
Primary peritoneal hydatidosis revealed by an abdominal mass in a case report
No full textHydatid cyst is caused by the parasite Echinococcus granulosus commonly found in temperate regions. Primary peritoneal hydatidosis is a rare entity. Diagnosis can be made with ultrasound and contrast-enhanced CT of the abdomen and pelvis and serology. Eosinophilia is a strong indicator of hydatid cysts as a differential diagnosis. Open excision of the cyst combined with medical treatment remains the treatment of choice.</p
<em>Mycoplasma pneumoniae</em>-induced rash and mucositis: A rare extrapulmonary manifestation of <me>mycoplasma pneumoniae</em> infection
No full textMycoplasma pneumoniae (M. pneumoniae) is a common atypical pathogen in humans, causing community-acquired pneumonia. Isolated Mycoplasma pneumoniae cases are commonly seen in the community, but an extrapulmonary manifestation like severe mucositis without skin lesions is rarely seen. The Mycoplasma-Induced Rash and Mucositis (MIRM) or Mycoplasma Pneumoniae-Associated Mucositis (MPAM) is a severe manifestation of an atypical organism. Still, morbidity and mortality are less than Mycoplasma-Associated Steven Johnson’s Syndrome (MASJS) and Toxic Epidermal Necrolysis (TEN). We reported a case of a young adult admitted with pneumonia and rapidly developed severe mucositis without skin manifestations, which has increased his morbidity and recovery time.</p
The effect of the "Golden Circle" exercise on personal goal achievements of stroke survivors: Preliminary findings
No full textThe success of a patient's rehabilitation depends greatly on many variables. Stroke survivors are often not sufficiently or fully aware of their mental health condition, and as a result are unresponsive, frustrated, and have difficulty with executive functions. The aim was to investigate the effect of the "Golden Circle" cognitive exercise on the quality of life of post-stroke patients.The subjects were 30 volunteers at a subacute stage after an ischemic stroke. They were randomly allocated to either an experimental group (n = 15) or a control group (n = 15). Quality of life questionnaire and Visual Analogue Scale administered. They were asked to draw a circle on a blank A4 page and at the top to write a title, and within the circle to write their problems, their suggested solutions and to intuitively write associations to a color, a taste, an animal, and a general physical sensation, and below these the date.Following the intervention experimental group showed improvement in walking, standing up, daily activities and general quality of life.Using the "Golden Circle" exercise to improve self-awareness and motivation in stroke survivors contributes to coping and taking responsibility for their rehabilitation.</p
Sleep and bipolar disorder
No full textA growing international scientific literature demonstrates the existence of sleep abnormalities and sleep/wake (or circadian) rhythms in bipolar disorder. These abnormalities exist during the acute phases of the disease, with the classic presentation of insomnia or hypersomnia during depressive episodes and a reduced need for sleep without feeling tired during manic episodes. But these disturbances can also appear or persist during phases of mood stability. However, it has now been clearly demonstrated that these disturbances can precipitate a new depressive or manic episode.</p
Organic and inorganic light-emitting diodes for photodynamic therapy of cutaneous leishmaniasis
No full textFor effectively fighting worldwide infectious diseases such as cutaneous leishmaniasis, novel approaches are required. Photodynamic Therapy (PDT) is one such possibility. PDT involves applying a light-sensitive chemical (photosensitizer), which should be highly efficient, non-toxic, and work at longer light wavelengths. This photosensitizer needs to be activated by a light source that provides uniform emission over a large area, high intensity, easy to fabricate, compact, and low cost. In this work, we designed and built light sources based upon commercially available Organic Light Emitting Diode (OLED) and LED parts to experimentally validate the combination with methylene blue photosensitizer to kill Leishmania major and Crithidia fasciculata cells in vitro. Our results showed that suitable-sized OLEDs, as compact and uniform light sources, are very good candidates for photodynamic therapy and can be used to efficiently kill such kinetoplastids in vitro. Therefore, it has real potential to be used in wearable devices for ambulatory treatment of patients.</p