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A wound index for hip and knee arthroplasty outcomes: a pilot investigation
No full textBackground: Post-arthroplasty infections pose a challenge in surgery, often necessitating pro-longed antibiotic treatment, implant failure, and revision surgery. To optimize patient outcomes and resource allocation, the present study aimed at test whether the implementation of the ASEPSIS score (i.e., a prognostic indicator based on postoperative variables) would emerge as an effective index to foresee future post-arthroplasty infections and to guide targeted interventions. Methods: We conducted an evaluation of hip and knee replacement patients' progress during their hospital stay, utilizing the ASEPSIS score. Subsequently, we conducted telephone interviews to evaluate the outcomes of their surgical wounds. Results: A robust correlation was observed between this score and the incidence of post-operative infections. Notably, individuals with a lower score exhibited a reduced likelihood of infection, whereas those identified as high-risk were more predisposed to develop infections within 90 days of surgery. Conclusions: While these findings are preliminary, they demonstrate significant promise. As we progress with subsequent studies, employing the validated assessment method from this pilot study, we anticipate further validation of the ASEPSIS score and its potential integration into standard clinical practice
N. Flora, Disegni dal finestrino. 50 + 1 disegni per essere dentro i luoghi, Cratèra, Napoli 2024.
No full textRecensione del libro N. Flora: "Disegni dal finestrino
Lavoratori “del braccio” e “della mente” nell’interpretazione del concetto di “manodopera” nel delitto di intermediazione illecita e sfruttamento del lavoro
No full textIl delitto di intermediazione illecita e sfruttamento del lavoro; il concetto di "manodopera" espresso nell'art. 603 bis c.p.; la sua limitazione ai c.d. "lavoratori manuali"; il c.d. "lavoro intellettuale; i criteri interpretativi dela fattispecie; l'occasio legis; lo "stato di bisogno" ed il suo "sfruttamento"; l'interpretazione e la formulazione letterale della previsione normativa; il lavoro e la Costituzione; lavoro "dipendente" ed "autonomo" nella fattispecie de qua; i rapporti con il delitto di estorsione
A Study of the Effects of Oleuropein and Polydatin Association on Muscle and Bone Metabolism
Get PDFSarcopenia and osteoporosis are age-related musculoskeletal pathologies that
often develop in parallel, and numerous studies support the concept of a bone–muscle
unit, where deep interaction between the two tissues takes place. In Mediterranean areas,
the lowest incidence of osteoporosis within Europe is observed, so the Mediterranean
diet was suggested to play an important role. Consequently, in this study, oleuropein, a
phenolic compound found in olive oil, and polydatin, another natural polyphenol found in
the Mediterranean diet, were evaluated to determine their beneficial effects on bone and
muscle metabolism. In human osteoblasts and skeletal muscle myoblasts, the effects were
examined, and, after analyzing the cytotoxic effect to find non-toxic doses, the modulation
of bone and muscle differentiation markers was evaluated at the gene and protein levels us-
ing PCR, Western blot, and immunohistochemistry. Interestingly, the compounds increased
markers involved in osteoblast differentiation, such as osteocalcin, type I collagen, and
dentin-sialo-phosphoprotein, as well as markers involved in myoblast differentiation, such
as myogenic regulatory factors and creatine kinase. These effects were most noticeable
when the compounds were administered together. These results suggest a beneficial role for
oleuropein–polydatin association on bone and muscle tissue pathologies simultaneously
Diritto e management delle strutture sanitarie e dei dipartimenti farmaceutici
No full textIl manuale, frutto dell’esperienza di oltre un
decennio nello svolgimento dei corsi di formazione
manageriale per i professionisti della sanità
organizzati dall’Università di Camerino in
collaborazione con la Regione Marche, offre al
lettore un quadro complessivo del diritto sanitario,
del management delle strutture sanitarie e dei
dipartimenti farmaceutici, insieme agli strumenti
necessari per la comprensione del funzionamento
degli istituti che regolano il settore e dei principi
posti a loro fondamento.
Il volume si rivolge sia ai professionisti che
vogliono conoscere o approfondire la cornice
normativa e teorica in cui si trovano ad operare
quotidianamente, sia a quanti per la prima volta,
per fini di studio o interesse personale, intendono
avvicinarsi ai temi trattati.
La comprensione di un sistema altamente
complesso, qual è la sanità e la gestione delle sue
strutture, richiede l’interazione tra più ambiti di
conoscenza.
Perciò il testo ospita contributi di esperti di materie
diverse, che vanno dalle discipline giuridiche al
management, alla comunicazione, al marketing
"Design driven Companies", Convegno organizzato da ADI MAM e Confindustria Ascoli Piceno con il supporto della Scuola di Architettura e Design dell'Università di Camerino, Sala degli Specchi, Confindustria AP, 13 giugno 2025
No full textIl Convegno "Design driven Companies" aveva l'obiettivo di approfondire l'importanza e il valore del design per le imprese italiane, attraverso le storie di tre importanti aziende "design driven": Fiam Italia, Tecno, Elica. Tre aziende profondamente diverse ma che hanno scritto con i loro prodotti le pagine della storia del design italiano e reso grande e apprezzato il Made in Italy nel mondo
Circular and Sustainable Product Design. Rethinking the Modularity as a Strategy to Increase the Durability of Industrial Products
No full textIn recent years, the industrial production system has become challenged by environmental concerns and moving towards sustainable models. In this scenario, the Circular Economy (CE) represents a virtuous, closed-loop production model capable of optimising the environmental impact of goods by reusing outputs in technical and biological cycles and extending the life of products as far as possible. CE focuses on the design phase and the concept of 'modularity', applied through Design for Modularity (DfM) strategies, is consolidated as a key action to reduce environmental impact and improve product durability. Modularity makes it possible to prolong the use phase of the products by means of repairs, upgrades and remanufacturing. Several studies confirm the importance of DfM in design, both to develop more sustainable and durable products and to help manufacturing companies move towards circular and sustainable models. Through the analysis of case studies of products designed with a DfM approach and in line with SDG 12 and UN Target 12.5, the article aims to examine the importance of modularity as a key strategy to enhance the circularity and sustainability of industrial products in the circular economy
HORIZON-EIC-2025-PATHFINDEROPEN Briefing and evaluation Proposal no. 1012584**
No full textEXPERT CONTRACT NUMBER - CT-EX2002B071944-11
HORIZON-EIC-2025-PATHFINDEROPEN Briefing and evaluation proposal no. 101259***
No full textContract number: CT-EX2002B071944-112
Contracting authority: European Research Executive Agenc