University of Camerino

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    Dispersal Patterns of Euphydryas aurinia provincialis (Lepidoptera: Nymphalidae) in the Colfiorito Highlands, Central Italy

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    We investigated the dispersal ability of Euphydryas aurinia provincialis in a local-scale analysis within a single habitat patch of the Colfiorito highlands metapopulation. Our findings indicate that inside a single node, the organization of nesting patches can be conceptualized as a metapopulation itself, where reproductive sites, despite their spatial proximity, can act as either source or sink habitats depending on environmental conditions. We conducted fieldwork in six nesting patches inside a single node, capturing, marking, and recapturing individuals to assess their spatial distribution and movement tendencies at a large landscape scale. We found a high degree of site fidelity among individuals, with many recaptures occurring within the original marking site, but also a sex-based difference in movement patterns; females dispersed farther than males, likely driven by reproductive strategies, while males remained more localized, prioritizing mate-searching. Our findings suggest a complex dynamic in habitat connectivity: pastures and abandoned fields, despite being open, seem to act like sink areas, while breeding sites with shrub and tree cover act as source habitats, offering optimal conditions for reproduction. Individuals, especially females, from these source areas were later compelled to disperse into open habitats, highlighting a nuanced interaction between landscape structure and population dynamics. These results highlight the importance of maintaining habitat corridors to support metapopulation dynamics and prevent genetic isolation; the abandonment of traditional grazing practices is leading to the rapid closure of these source habitats, posing a severe risk of local extinction. Conservation efforts should prioritize the preservation of these source habitats to ensure the long-term viability of E. a. provincialis populations in fragmented landscapes

    An Efficient Sparse Twin Parametric Insensitive Support Vector Regression Model

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    This paper proposes a novel sparse twin parametric insensitive support vector regression(STPISVR) model, designed to enhance sparsity and improve generalization performance.Similar to twin parametric insensitive support vector regression (TPISVR), STPISVR constructsa pair of nonparallel parametric insensitive bound functions to indirectly determinethe regression function. The optimization problems are reformulated as two sparse linearprogramming problems (LPPs), rather than traditional quadratic programming problems(QPPs). The two LPPs are originally derived from initial L1-norm regularization termsimposed on their respective dual variables, which are simplified to constants via theKarush–Kuhn–Tucker (KKT) conditions and consequently disappear. This simplificationreduces model complexity, while the constraints constructed through the KKT conditions—particularly their geometric properties—effectively ensure sparsity. Moreover, a two-stagehybrid tuning strategy—combining grid search for coarse parameter space exploration andBayesian optimization for fine-grained convergence—is proposed to precisely select theoptimal parameters, reducing tuning time and improving accuracy compared to a singlemethodstrategy. Experimental results on synthetic and benchmark datasets demonstratethat STPISVR significantly reduces the number of support vectors (SVs), thereby improvingprediction speed and achieving a favorable trade-off among prediction accuracy, sparsity,and computational efficiency. Overall, STPISVR enhances generalization ability, promotessparsity, and improves prediction efficiency, making it a competitive tool for regressiontasks, especially in handling complex data structures

    3D quantification of nanolites using X-ray ptychography reveals syn-eruptive nanocrystallisation impacts magma rheology

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    Nanoscale crystals are becoming increasingly recognised in the products of volcanic eruptions, spanning a range of magma compositions. The crystal- lisation of nanolites impacts magma rheology, ascent dynamics, and eruptive style. Their impact can be enhanced due to their capacity to aggregate and develop neighbouring chemically differentiated boundary layers. However, their 3D interaction, spatial distribution, and morphology is not currently understood. Here we present a cutting-edge, 3D nanometre-scale visualisation and quantification of nanolites in scoriae of the Las Sierras-Masaya basaltic Plinian eruptions, acquired using X-ray ptychography. We find that Ti- magnetite nanolites aggregate, forming elongate, irregular structures in 3D. Their crystallisation extracts Fe and Ti from the melt, resulting in differ- entiated boundary layers with higher viscosity. Syn-eruptive crystallisation of nanolites and their interaction is estimated to have increased magma viscosity by 2–3 orders of magnitude, therefore, they likely had a strong control on magma rheology, increasing the potential of magma fragmentation

    Diritto e management delle strutture sanitarie e dei dipartimenti farmaceutici

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    Il manuale, frutto dell’esperienza di oltre un decennio nello svolgimento dei corsi di formazione manageriale per i professionisti della sanità organizzati dall’Università di Camerino in collaborazione con la Regione Marche, offre al lettore un quadro complessivo del diritto sanitario, del management delle strutture sanitarie e dei dipartimenti farmaceutici, insieme agli strumenti necessari per la comprensione del funzionamento degli istituti che regolano il settore e dei principi posti a loro fondamento. Il volume si rivolge sia ai professionisti che vogliono conoscere o approfondire la cornice normativa e teorica in cui si trovano ad operare quotidianamente, sia a quanti per la prima volta, per fini di studio o interesse personale, intendono avvicinarsi ai temi trattati. La comprensione di un sistema altamente complesso, qual è la sanità e la gestione delle sue strutture, richiede l’interazione tra più ambiti di conoscenza. Perciò il testo ospita contributi di esperti di materie diverse, che vanno dalle discipline giuridiche al management, alla comunicazione, al marketing

    Toward the Optimal Choice of Gelled Vehicles for Oral Drug Administration in Dysphagic Patients

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    Background/Objectives: Thickened waters are commonly used for dysphagic patients to ensure hydration, facilitate safer swallowing, and administer oral therapies, yet their impact on drug dissolution remains unclear. This study aims to investigate how thickening agents, viscosity, and solid oral dosage form (SODF) formulations influence drug release in gelled vehicles. Methods: Twelve commercially available thickened waters, including both ready-to-use products and powders for extemporaneous preparation, were used to disperse crushed sodium pravastatin tablets. The resulting preparations were evaluated for their rheological properties and dissolution performance. Results: Thickened water products vary in consistency, with starch-based thickeners providing more consistent results than gum-based ones. Pravastatin release profiles closely matched the original tablets with starch thickeners, while gum-based thickeners showed greater variability, primarily influenced by viscosity. Conclusions: These findings emphasize the importance of selecting the appropriate thickening agent for controlling drug release in thickened water products, highlighting the need to balance patient compliance with the potential impact on drug release during product development

    International Meeting SUNRISE

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    The post-disaster recovery after the 2016 earthquakes in central Italy: planning solutions in the light of the new European strategie

    NGEU: una trasformazione costituzionale implicita o semplicemente un caso eccezionale e irripetibile?

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    Il contributo analizza il procedimento di adesione dell'Italia al NGEU, l'adozione del PNRR e gli effetti di tali strumenti sulle dinamiche interne alla forma di govern

    Investigating the temporal Alpha, Beta and Gamma plant diversity on 22 years monitoring approach at the LTER site “Montagna di Torricchio” (Central Apennines, Italy)

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    Ecological monitoring recently acquired importance given the current global changes and the human impact on ecosystems. Most of research focus on investigating variation in species diversity with short-term collections of data. Other scholars use long-term data but based on resurveys with two distinct points in time. In this work, we present a different approach dealing with temporal variation of plant communities in term of alpha, beta and gamma diversity. Data belongs to a dataset published on the journal “Data in Brief” as a data article and available on the repository “b2Share” (https://doi.org/10.34730/044c89dc80f648d18d0ce236600b8584). These data represent a long-lasting monitoring of 22 years with 5 monitoring sessions (2002, 2003, 2015, 2020, 2024) at the LTER site “Montagna di Torricchio” (Central Apennines, Italy). Data were collected following a probabilistic sampling scheme based on 35 permanent plots (10 m x 10 m). Preliminary analysis of alpha and gamma diversity (through presence/absence matrix) pointed out that the species richness is stable through years despite climatic fluctuations. Indeed, the vegetative season of 2003 had 47% less precipitation than that of 2002, and 57% less than that of 2015. Grouping the plots according to habitats (i.e., grassland, beech forest, and transition from grassland to forest) revealed that the above-mentioned pattern depends on a greater variability of grassland and transition habitats. On the contrary, beech forests show a high stability of species richness over time, probably depending on the effect of tree canopies on grass species and to buffer macroclimate extremes. In addition, the analysis of beta diversity showed remarkable values of the turnover component over time with surprising results for the beech forest habitat. Changes in composition might evidence a pattern of change in the LTER site of Torricchio. Nevertheless, our results suggest that 22 years of monitoring could be insufficient to make reliable inferences on long-lasting vegetation dynamics in our LTER site. This highlights the need to continue the long-term monitoring with frequent re-surveys over time

    City Rhythm: geo-temporal platform for integrated analysis of flows, microclimate and UHI risk

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    Mitigating the Urban Heat Island (UHI) effect is a critical challenge for contemporary urban design, impacting thermal comfort and public space usability. Effective mitigation requires understanding human flow dynamics within Local Climate Zones (LCZ), which define urban microclimates. Current analyses are often limited by static methodologies and fragmented datasets. This study introduces City Rhythm, an interactive web-based platform that enables dynamic (hourly/weekly) analysis of inferred human presence, LCZ classification and UHI risk. The platform simultaneously visualises spatiotemporal patterns, allowing users to overlay modelled Presence Points with LCZ and UHI maps, correlating them with inferred demographic and interest data. For example, it can identify peaks in vulnerable populations, like the elderly, in compact LCZ areas during high-risk UHI periods. City Rhythm innovatively explores human-environment interactions through multi-source data integration and dynamic modelling, identifying critical areas of high human presence and UHI risk, analysing user characteristics and providing data-driven strategies for UHI mitigation and enhanced thermal comfort

    Traumatic Oral Lesions in Loggerhead Sea Turtles (Caretta caretta) Linked to Polychaete (Laetmonice cf. hystrix) Ingestion: A Case Report from the Northern Adriatic Sea

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    Oral cavity lesions in sea turtles, particularly Caretta caretta, are relatively rare, and are typically linked to infectious agents as well as anthropogenic factors, including ingestion of marine debris or fishing gear. This report describes a juvenile Caretta caretta found in the northern Adriatic Sea with severe oral lesions affecting the choanae, alimentary tract, and larynx. A comprehensive clinical and histopathological evaluation was conducted, which revealed traumatic injuries caused by the ingestion of a polychaete, Laetmonice cf. hystrix. Mucosal biopsies in the areas of spine penetration revealed the presence of strong sub-epithelial inflammation, characterised by micro-abscesses. In addition, around some fragments of spines, the formation of microgranulomatous lesions with a tendency to encapsulation was observed. Treatment protocol involved the removal of embedded spines and administration of a broad-spectrum antibiotic to prevent secondary infections. Recently, the detection in polychaetes of the aetiological agents of two newly emerging diseases of shrimps, suggests that these worms can be a host or/and passive carrier of these pathogens. This case study underscores the necessity to consider both biological and anthropogenic factors in diagnosing and managing oral lesions in marine turtles. Furthermore, it draws attention to the ecological risks posed by interactions between sea turtles and benthic organisms

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