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Workshop "NUOVI CONCEPT DI PRODOTTI E SISTEMI FUNZIONALI IN AMBITO COSMETICO E VINICOLO", 9/20 giugno 2025, Scuola di Architettura e Design, sede di Sant'Angelo Magno.
No full textIl workshop, guidato dal designer Gaudenzio Ciotti e realizzato in collaborazione con l’azienda Omada, si è concentrato sulla progettazione di oggetti e accessori di alta gamma per i settori vinicolo e cosmetico, attraverso l’utilizzo di materiali biocompositi a base di fibre vegetali, provenienti rispettivamente da vinacce e camomilla. Partendo da tre funzioni chiave – contenere, utilizzare e conservare – il workshop progettuale si è proposto di sviluppare soluzioni innovative e sostenibili che valorizzino il prodotto e ne estendano l’esperienza d’uso. Nel settore vinicolo, l’attenzione sarà rivolta a gadget e accessori legati alla bottiglia di vino, come glacette, cantinette e strumenti per il servizio e la conservazione, concepiti in un’ottica di economia circolare. Per la cosmesi, i nuovi concept di prodotto sono stati pensati per migliorare l’esperienza e la ritualità per la cura della persona, come mini beauty da viaggio, contenitori per formati speciali, accompagnati da accessori e strumenti progettati per facilitarne l’utilizzo, con particolare attenzione al linguaggio formale, alla trasportabilità e alla qualità sensoriale. Particolare attenzione è stata dedicata anche alla comunicazione dei concept, con l’obiettivo di valorizzare le pratiche sostenibili adottate attraverso un linguaggio coerente, chiaro e capace di rafforzare l’identità del progetto. Il workshop ha rappresentato un’occasione per sperimentare linguaggi e materiali innovativi, capaci di raccontare il prodotto attraverso soluzioni che coniughino qualità progettuale, valore emozionale e sostenibilità ambientale
The Functionality of Probiotics in Aquaculture: Application; Mechanisms, Current Status, and Future Prospects - A comprehensive review
No full textDespite being the fastest-growing food production sector, aquaculture faces significant challenges, including shortages and limitations of protein sources for feed, susceptibility to infections, and quality deterioration during growth and storage. Beneficial microbial species can protect aquatic organisms from diseases and prevent product deterioration, while bacterial biomass represents a promising alternative protein source for animal feed. Probiotics are widely acknowledged as powerful microorganisms that significantly impact gut health by positively modulating the gut microbiome and, consequently, immune system and disease outcome in humans and animals. This review focuses on nutritional, anti-pathogenic, and immunoregulatory functions of probiotics in aquaculture. Additionally, the connection between host immunity, gut microbiota, beneficial bacteria, their components and specific metabolites – as well as their immunomodulatory activity and innovative applications – are considered and described
Algorand’s Path to Flexibility in Decentralized Applications
No full textThe Algorand blockchain technology is gaining great interest as its consensus protocol permits to address the blockchain trilemma; i.e., this blockchain can be simultaneously scalable, secure, and decentralized. Algorand also achieves high throughput and low latency. Besides this, Algorand introduces relevant novelties also on the features supported by its smart contracts. In particular, Algorand provides remarkable flexibility for writing, updating, and deleting smart contracts. This paper examines Algorand’s approach to smart contract flexibility, focusing on the update of a deployed smart contract, enabling the definition of dynamic and adaptable decentralized applications. We illustrate Algorand’s capabilities in enhancing decentralized application flexibility by resorting to a case study from the e-commerce domain
Belvedere ed ecclesia sine tecto.
No full textIl contributo pone uno sguardo analitico e uno progettuale intorno al Monte Grifone, un ambito identitario del paesaggio palermitano dove la presenza umana si integra alla natura e dove l’azione antropica si mostra con un legame profondo e antico con i suoi elementi originari: il suolo, l’acqua e la vegetazione
The Impact of Artificial Intelligence Technologies on Nutritional Care in Patients With Chronic Kidney Disease: A Systematic Review
No full textObjectives: Chronic kidney disease is a global health challenge, and effective, individualized nutritional management is crucial for slowing progression and improving quality of life. Artificial intelligence (AI) offers innovative tools to optimize and personalize nutritional care. This review explores AI applications in nutritional management, assessing their impact on clinical outcomes, quality of life, and care efficiency. Methods: A systematic review was conducted, reported according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Searches were performed on 5 databases, namely MEDLINE, Embase, Cochrane Library, Cumulative Index to Nursing and Allied Health Literature, and integrated with gray literature sources between September and November 2024. The methodological quality assessment was conducted independently by 2 researchers using the Joanna Briggs Institute methodology. Results: Of 2,053 initial records, 7 studies met inclusion criteria. AI showed significant potential in personalizing dietary recommendations using machine learning, clinical decision support systems, and generative AI tools. These systems tailored nutritional advice based on patient-specific clinical data, reducing complications such as hyperkalemia and improving adherence. AI also facilitated early risk detection and proactive care by monitoring nutritional parameters and predicting complications. In addition, AI-powered platforms enhanced patient education through culturally relevant, intuitive dietary plans and multilingual materials, increasing engagement. AI also improved health care efficiency by automating tasks and integrating with electronic health records. Conclusions: AI technologies show promise in enhancing nutritional care for patients with chronic kidney disease. Evidence supports their role in improving care quality and dietary adherence. Further research is needed to validate these technologies in clinical practice and ensure integration into routine care pathways
Rassegna a: L. GAROFALO, Il diritto oltre i giuristi, «Saggi» (Venezia, Marsilio, 2024) p. 432
No full textCONFERENZA DI CHIUSURA DEL PROGETTO VITALITY/SPOKE 6/WP3 E INAUGURAZIONE DEL 2° PROGETTO PILOTA: SISTEMA DI VARCHI SALVA-VITA IN CASO DI SISMA, Sede dell'Annunziata, Scuola di Architettura e Design dell'Università di Camerino, Ascoli Piceno, 16 dicembre 2025.
No full textL'evento ha rappresentato la chiusura e la disseminazione pubblica dei principali risultati del WP3 "Design sostenibile di un sistema di arredi intelligenti con funzione salva-vita in condizioni di emergenza per contesti comunitari" dello Spoke 6 "Innovazione e sicurezza negli ambienti di vita nell'era della transizione digitale e verde" del progetto "Vitality. Ecosistema di Innovazione, Digitalizzazione e Sostenibilità per l’Economia Diffusa nell’Italia Centrale", finanziato dall’Unione Europea - NextGenerationEU, Missione 4, Componente 2, nell’ambito del programma Ecosistema Nazionale dell’Innovazione del Ministero dell’Università e della Ricerca (MUR) ECS00000041 - VITALITY - CUPJ13C22000430001.
Sono stati presentati tutti i principali risultati dell'attività di ricerca del WP3, in particolare: 1° Progetto pilota: allestimento della Scuola ITT E. Fermi di Ascoli Piceno con il sistema di arredi «Life-saving Furniture system» (dicembre 2023); 2° Progetto pilota: installazione nella Scuola di Architettura e Design di Unicam del sistema di «varchi salva-vita in caso di sisma» (dicembre 2025); Progettazione, protipazione e realizzazione di 6 tipologie di arredi salva-vita per le scuole e di un sistema di varchi salva-vita in differenti declinazioni (con e senza porta, opaco e trasparente, ecc.); Risultati del monitoraggio del gradimento degli arredi scolastici da parte di studenti e docenti (2024-2025); Risultati dei test strutturali sugli arredi con nuove prove e nuovi strumenti; Tool digitale di apprendimento del funzionamento degli arredi salva-vita e dei comportamenti corretti da adottare; Disciplinare sugli arredi scolastici con funzione salva-vita in caso di sisma e relativo logo; Numerose pubblicazioni scientifiche (2 libri, articoli, saggi, ecc.); Numerose partecipazioni a convegni e congressi nazionali e internazionali; Eventi di disseminazione (conferenze e inaugurazioni aperte al pubblico, seminari, ecc.); Edizione 2024/25 del Master in Eco-design & Eco-innovazione: 11 diplomati (19 dicembre 2025); 2 brevetti d’invenzione relativi ai risultati progettuali del Master.
Il Convegno si è aperto con i saluti istituzionali di Graziano Leoni - Rettore dell’Università di Camerino; Guido Castelli - Commissario Straordinario alla Ricostruzione, Massimo Sargolini - Direttore della Scuola di Architettura e Design dell’Università di Camerino. Poi si sono tenuti gli interventi introduttivi di Fabrizio Cobis - Dirigente responsabile dell'Ufficio II - Direzione generale della ricerca, Ministero dell'Università e della Ricerca; Fabio Graziosi - Coordinatore dell’Ecosistema dell'Innovazione Vitality – Rettore dell’Università dell’Aquila, Flavio Corradini - Coordinatore dello Spoke 6 del Progetto Vitality – Professore di Informatica dell’Università di Camerino; Lucia Pietroni - Responsabile del WP3 del Progetto Vitality – Professore di Disegno Industriale dell’Università di Camerino, Andrea Dall’Asta – Professore di Ingegneria Strutturale dell’Università di Camerino. A seguire i gruppi di ricerca in Design, Ingegneria Strutturale e Disegno hanno presentato gli esiti del lavoro di ricerca svolto dal 2022 e le prospettive di sviluppo. Ha chiuso il convegno l'intervento dei Alessio Gnaccarini e Matteo Bottenghi del Cosmob, partner affiliato del progetto. In conclusione al Convegno si è tenuta l'inaugurazione del sistema di varchi salva-vita in caso di sisma allestiti presso la Scuola di Architettura e Design dell'Università di Camerino. Tale sistema di protezione delle persone durante un terremoto è stato progettato e allestito dai seguenti professori e ricercatori: Lucia Pietroni, Alessandro Zona,
Daniele Galloppo, Ilaria Fabbri, Laura Gioiella, Fabio Micozzi, Davide Paciotti, Mariangela Francesca Balsamo. I prototipi dei varchi salva-vita sono stati realizzati dall'azienda Tre Elle
Biological Effects of Music Therapy in End-of-Life Care: A Narrative Review
No full textBackground and Objectives: Music therapy has a long tradition in palliative care, and recent studies have investigated its Neuro-Psycho-Endocrine-Immunological (NPEI) effects in terminally ill patients. Despite numerous published articles, there is a lack of a compendium connecting the physiological basis of music therapy with the specific musical elements most effective in end-of-life settings. This narrative review aims to synthesize current evidence on the physiological mechanisms underlying responses to music, with a focus on terminal patients and implications for nursing practice. Materials and Methods: For quality and possible reproducibility, a narrative review was conducted in accordance with Scale for the Assessment of Narrative Review Articles (SANRA) guidelines. The review targeted articles from the past five years indexed in PubMed, CINAHL, Cochrane Library, Embase, Scopus, Web of Science, and PsycInfo, supplemented by additional relevant references identified through manual searching. The PICOS framework was performed to structure the search strategy and study selection, focusing on studies relevant to the biological effects of music therapy in end-of-life care and their practical implications for nursing care. Results: The neurophysiology of music perception in terminal patients is complex, involving a wide array of clinical and cultural factors. Key musical elements—such as rhythm, melody, harmony, tempo, and mode—can influence physiological and psycho-emotional responses. Music therapy interventions, when tailored to the individual’s preferences and cultural background, may modulate parameters like heart rate, blood pressure, stress hormone levels, and pain perception. Evidence supports the need for individualized approaches and highlights the NPEI rationale for integrating music therapy into end-of-life care. Conclusions: A deeper understanding of the scientific mechanisms discussed in this narrative review can enhance the effectiveness of music therapy interventions in end-of-life settings. Nursing practice can benefit by integrating evidence-based selection of musical pieces and personalizing interventions to the clinical and cultural profile of each patient. Further interdisciplinary research is needed to establish standardized criteria for music therapy in palliative care and to optimize outcomes for terminally ill patients
Investigation of the Chemical Composition and Biological Activities of Eremurus spectabilis M. Bieb through Antioxidant, Enzyme Inhibition, COX-2 and iNOS Assessment
No full textEremurus spectabilis is widespread and used primarily for medicinal and culinary purposes. This study aimed to evaluate the chemical composition, antiradical and antioxidant activities, enzyme inhibitory activities, and anti-inflammatory properties of various extracts from the aerial parts of E. spectabilis. Various assays were used to investigate the antioxidant and enzyme inhibitory properties. The chemical composition of the tested extracts was analyzed using High-Performance Liquid Chromatography-Electrospray Ionization Tandem Mass Spectrometry (HPLC-ESI-MS/MS). Additionally, the extracts were tested on isolated mouse colon tissue challenged with E. coli lipopolysaccharide (LPS) to replicate the inflammation and oxidative stress burden characteristic of inflammatory bowel diseases. In the chemical composition, vanillic, ferulic, and 4-hydroxybenzoic acids were the prominent compounds. The greatest antioxidant activity was observed in the methanol and water extracts from the aerial parts. Enzyme inhibition tests showed that the ethyl acetate extract had the highest anti-acetylcholinesterase activity. The gene expression of pro-inflammatory cyclooxygenase-2 (COX-2) and pro-oxidant inducible nitric oxide synthase (iNOS) biomarkers were assayed. Among the extracts, the methanol extract was the most effective in blunting LPS-induced gene expression of COX-2. E. spectabilis may serve as a valuable source of phytochemicals for combating oxidative stress and inflammation-driven diseases, with a particular emphasis on colon inflammatory condition
Efficacy of willow herb (Epilobium angustifolium L. and E. parviflorum Schreb.) crude and purified extracts and oenothein B against prostatic pathogens
No full textBackground/Objectives: Plants species of the Epilobium genus are traditionally used to treat prostatitis and other urinary tract disorders and are particularly rich in ellagitannins and flavonol 3-O-glycosides. The aim of this work was to evaluate the inhibitory activity of different extracts from E. angustifolium L. and E. parviflorum Schreb. and their major bioactive compound, oenothein B, against a panel of Gram-positive (Enterococcus faecalis ATCC 29212, Enterococcus faecalis BS, Staphylococcus aureus ATCC 25923, Staphylococcus aureus ATCC 29213, and Staphylococcus aureus ATCC 43300) and Gram-negative (Escherichia coli ATCC 25922, Escherichia coli ATCC 35218, Escherichia coli BS, Klebsiella pneumoniae ATCC 13883, Klebsiella pneumoniae ATCC 70063, Klebsiella pneumoniae BS, Proteus mirabilis BS, and Pseudomonas aeruginosa ATCC 27853) bacteria responsible for prostatitis. Methods: Aqueous and ethanolic raw extracts were prepared, and the latter were further purified using the resin AmberliteTM XAD7HP. Then, an HPLC-MS/MS method was developed for the quantification of the marker bioactives and their levels were correlated with the antimicrobial activity. Results: Purified extracts were richer in polyphenols (330.80 and 367.66 mg/g of dry extract for E. angustifolium and E. parvifolium, respectively) than the raw extracts. Oenothein B was the predominant compound in all the extracts (119.98 to 327.57 mg/g of dry extract). The minimum inhibitory concentrations (MICs) in the range of μg/mL indicated significant antibacterial activity, which was higher for the purified extracts and oenothein B (MIC values from 4 to 16 and 8 to 1024 μg/mL on Gram-positive and Gram-negative strains, respectively). Conclusions: These results outline the outstanding potential of E. angustifolium and E. parviflorum extracts and oenothein B as therapeutic alternatives or complementary agents to conventional antibiotic treatments of prostatitis and other urinary tract infections