University of Bari Aldo Moro
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Blow up for nonlinear wave-type equations with perturbed derivatives
No full textWe investigate semilinear wave-type equations that can be recast as wave equations with derivatives perturbed by zero-order terms. This framework covers several well-studied cases, including the scale-invariant wave equation. In this setting, we refine existing blow-up results for radial initial data with suitable decay, and identify conditions on the zero-order terms that govern the interplay between derivative perturbations, initial data size, and nonlinearity exponent
National average dental fee schedule 2025: a reference for the medicolegal evaluation of economic damages in Italian Civil Law
No full textBACKGROUND
The medicolegal evaluation of dental damages in civil litigation plays a crucial role in establishing causal relationships and determining appropriate therapeutic interventions to restore pre-injury functional and aesthetic conditions. This assessment also includes anticipating future treatment needs, especially in prosthetic and conservative dental care, based on the average clinical lifespan of interventions. Medicolegal consultants are responsible for verifying the adequacy of dental expenses, both incurred and projected, submitted by claimants, particularly in insurance and civil liability disputes.
METHODS
In Italy, the abolition of national minimum fees for medical and dental services resulted in the development of alternative nomenclatures and fee schedules by professional associations and scientific societies between 2005 and 2009. These initiatives aimed to create a standardized and transparent framework for communication between dental professionals and patients. The study evaluates national dental treatment costs by applying inflation-adjusted criteria to the fee schedules established by the Italian National Institute of Statistics (ISTAT) and the National Association of Italian Dentists (ANDI) in 2009. Additionally, reimbursement data from private insurance providers and fee schedules from the Italian Academy of Legal and Forensic Dentistry and regional Dental Councils are integrated into the analysis.
RESULTS
The study proposes a National Average Dental Fee Schedule 2025, calibrated to reflect contemporary clinical, economic, and professional realities. This updated fee schedule is 8.8% lower than the 2009 ANDI fee schedule and 13.7% lower than national fee schedules developed by the Italian Academy of Legal and Forensic Dentistry. The new schedule aims to serve as a standardized reference in legal and forensic dentistry, aligning with best practices for assessing economic damages in civil dental law cases and evaluating the appropriateness of dental service costs.
CONCLUSIONS
The National Average Dental Fee Schedule 2025 offers a comprehensive economic reassessment of dental treatment costs in Italy, addressing the technological, commercial, and organizational changes in the dental sector. By adapting to current realities, this new fee schedule provides a valuable tool for medicolegal professionals in assessing economic damages and determining the reasonableness of dental service expenses in civil legal proceedings
Andrea Faoro. I Consumati. La storia vera di una famiglia del Seicento tra affari, intrighi e monacazioni forzate. Limena (PD): libreriauniversitaria.it Edizioni, 2023
No full textRecensione al volume di A. Faor
Inverse problems in irregular domains: approximation via Mosco convergence
No full textWe consider inverse problems in an irregular domain and their suitable approximations, respectively. Under suitable assumptions, after stating wel-posedness results, we prove that the solutions of the approximating problems converge to the solution of the problem on via Mosco convergence. We also present some applications
Adapted Exercise and Adapted Sport as Rights of Health Citizenship in Italy: A Legal–Policy Rationale and Framework for Inclusion in the Livelli Essenziali di Assistenza (LEA) and the Role of the Chinesiologo
No full textBackground: Adapted exercise and adapted sport are proven, low-cost interventions for chronic disease prevention, management, and social inclusion. However, in Italy, neither is explicitly included in the Livelli Essenziali di Assistenza (LEA; nationally guaranteed essential healthcare services), creating unequal access, fragmented governance, and unstable funding. Provision remains largely dependent on regional schemes such as Palestre della Salute and Attività Fisica Adattata (AFA). Methods: We conducted a narrative review integrating evidence from international guidelines, systematic reviews, and key Italian legislative reforms (Legislative Decrees n. 36/2021, 163/2022, 120/2023). We also examined policy frameworks from Germany, Sweden, and Norway to identify transferable components that could support the development of a nationally guaranteed, rights-based system for adapted exercise and adapted sport. Results: Consistent evidence shows that adapted exercise improves functional capacity, quality of life, and clinical outcomes while reducing hospitalizations and healthcare expenditures. Adapted sport further enhances psychosocial well-being, inclusion, and participation among people with disabilities. Based on this evidence, we outline a legal-policy framework for LEA integration that places the chinesiologo at the center of multidisciplinary health teams, defines national standards for assessment, individualized programming, and monitoring, and introduces accreditation mechanisms for facilities and professionals. A blended financing approach is proposed, combining National Health Service (SSN) coverage with income-adjusted co-payments and targeted public–private partnerships. Conclusions: Explicit LEA inclusion of adapted exercise and adapted sport would translate scientific evidence into enforceable rights of health citizenship and ensure uniform national provision, in line with constitutional principles affirmed
by the Italian Court. Such reform would strengthen prevention and chronic-disease management and institutionalize the role of the chinesiologo within the SSN through nationally standardized yet regionally adaptable delivery models
Evaluation of Digestion Methods in Microplastic Recovery from Mussels (Mytilus galloprovincialis) for a Standardised Microplastic Isolation Protocol
No full textAlthough microplastics are known as bivalve mollusc contaminants, the standardisation of isolation protocols hasn't been developed yet. This study aims at assessing the best microplastic recovery rates and digestion efficiencies, applying two chemical reagents (10% KOH and 30% H2O2) across a wide range of known temperatures, on mussels (Mytilus galloprovincialis) contaminated with virgin microplastic standards. Both reagents provided good digestion efficiencies, but microplastic recovery was optimised employing 30% H2O2 at 50-60 degrees C, which also preserved polymer integrity. Indeed, recovery rates ranged from 88.75 to 91.86% at 50 and 60 degrees C, respectively, whereas 85.8 and 99.4% were the values of the digestion efficiency at 50 and 60 degrees C, respectively. Flotation and supernatant fractionation were found to be decisive parameters in maximising microplastic recovery; therefore, they shouldn't be overlooked. These findings lay the foundations for standardising microplastic isolation protocol from mussels, allowing for the reproducibility of data and consequently the comparison of different laboratories' results in order to concretely assess the risk for consumer health and lead to determining the benchmarks for food safety policymaking. Further studies are needed to standardise the method for the detection of microplastics from other foods
Antropocene ed ecosistema marino a Taranto. I mutamenti del Mar Piccolo a metà Ottocento
No full textAll’indomani dell’Unità, la nuova legislazione sulla pesca si preoccupò di valorizzare gli antichi regolamenti locali che tenevano conto delle diversa natura dei litorali italiani. Tra questi, oggetto di particolare attenzione fu il Mar Piccolo di Taranto, le cui capacità ittiogeniche subirono nel corso dell’Ottocento mutamenti significativi di natura antropica che
incisero sulla pescosità delle acque
A two-site collaborative study of electrical impedance myography for evaluation of disease progression in murine Duchenne muscular dystrophy models
No full textAccessibility to outcome measures that reliably assess disease pathology in preclinical studies are vital, especially for rare disorders such as Duchenne muscular dystrophy (DMD). The non-invasive technique of electrical impedance myography (EIM) has shown potential as an outcome measure in patients and mouse models of neuromuscular disorders. However, these preclinical observations have been limited to a single site. Here, we performed a longitudinal, parallel two-site study to assess the potential of EIM as an outcome measure by using two DMD mouse models – mdx mice on a C57BL/10ScSn/J or DBA/2J genetic background – differing in disease severity, and being hypertrophic and atrophic, respectively, over a ten-month period, in which mice were evaluated monthly. We found that longitudinally acquired phase values were the most reliable, with relatively minor differences between study sites. Histopathology, assessed at 8, 12, 28, or 52 weeks of age correlated well with EIM phase values in both models. Our findings highlight the applicability of EIM as a robust, preclinical outcome measure for DMD
Myosin-ATPase inhibitor in real-world patients with obstructive HCM: a report by the Cardiomyopathies and Pericardial Diseases WG of the Italian Society of Cardiology
No full textIntroductionApproximately two-thirds of patients suffering from hypertrophic cardiomyopathy present with an obstructive (HOCM) physiology. For years, medical therapy has been limited to beta blockers, verapamil and/or disopyramide. Recently, a novel class of drugs, the allosteric inhibitors of the cardiac-specific myosin head adenosine triphosphatase (ATPase), have been demonstrated to be effective in relieving the dynamic obstruction and related clinical condition. In July 2024 the Cardiomyopathies and Pericardial Diseases WG of the Italian Society of Cardiology started with a nationwide multicentre registry aimed at investigating the pathophysiology of dynamic obstruction in real-world patients with HOCM. Based on the medical records, this brief report deals with the proportion of patients who were eligible for Mavacamten based on the Explorer-HCM entry criteria, and then admitted for compassionate use by the end of 2024.Methods and resultsThe Hypertrophic Obstructive Physiology Study (HOPS) was designed as a registry on consecutive adult patients admitted to 19 tertiary Cardiac Centres in Italy until June 2024. A total of 424 patients, 53% males, aged 64 ± 13 years, were included. We retrospectively recognized 200 Mavacamten-eligible patients (47.2%) on 5 Explorer-HCM requirements. Forty out of this latter group, along with 15 more patients on 4 criteria, were admitted to the compassionate use programme (n = 55, 13% of the whole population). Forty-three showed subaortic obstruction and 12 a mid-ventricular variant. Ethical committee approval items varied among centres and regions.DiscussionThis study confirmed our recent demonstration that approximately half of real-world HOCM patients are suitable for Mavacamten therapy based on the full Explorer-HCM trial entry criteria. Due to the current limitation of compassionate use programmes in Italy, only one in four patients was admitted for treatment
Licenze digitali e tutela del consumatore nel mercato dell’editoria scolastica. Rapporto di ricerca.
No full textIl rapporto analizza le trasformazioni del mercato dell’editoria scolastica alla luce della crescente diffusione delle licenze digitali e delle criticità evidenziate dall’Autorità Garante della Concorrenza e del Mercato (AGCM) nella propria indagine conoscitiva del 2024. L’evoluzione dal modello tradizionale di vendita della copia fisica a un sistema ibrido, in cui la versione digitale del testo è resa disponibile tramite licenza d’uso, ha determinato una profonda riconfigurazione del rapporto tra editori, scuole, studenti e famiglie. Le licenze, spesso soggette a restrizioni tecnologiche (DRM), limitano la durata di accesso, le modalità di utilizzo e la possibilità di trasferire il contenuto, generando fenomeni di lock-in, impedendo il riuso del materiale negli anni successivi e annullando ogni possibilità di circolazione nel mercato dell’usato.
Il rapporto ricostruisce il quadro giuridico del fenomeno, esaminando i principi dell’esaurimento del diritto d’autore e della first sale doctrine nelle esperienze statunitense ed europea, mettendone in evidenza limiti e incoerenze applicative quando estesi ai beni digitali. L’assenza di un meccanismo di “esaurimento digitale” effettivo consente infatti agli editori di mantenere un controllo pressoché permanente sul prodotto, con ricadute significative sulla tutela contrattuale dei consumatori, sulla trasparenza delle condizioni di fruizione e sulla competitività del mercato.
In questo contesto, il rapporto propone alcune prime considerazioni critiche, evidenziando la necessità di un intervento regolatorio che assicuri maggiore interoperabilità, diritti effettivi di accesso e conservazione per gli studenti, nonché un riequilibrio tra esigenze di tutela del copyright e diritti degli utenti. Vengono inoltre valorizzati modelli alternativi come le risorse educative aperte (OER), che promuovono accessibilità, sostenibilità e riduzione delle barriere concorrenziali. L’analisi intende offrire un contributo utile al dibattito istituzionale e alla definizione di eventuali misure correttive da parte dell’Autorità.The present report examines the profound transformation of the Italian school publishing market following the widespread adoption of digital licenses, as highlighted by the Italian Competition Authority (AGCM) in its 2024 sector inquiry. The shift from the traditional sale of physical copies to a hybrid model—where digital versions of textbooks are accessible only through time-limited and highly restrictive licenses—has reshaped the relationship between publishers, schools, students, and families. Digital licenses, often managed through Digital Rights Management (DRM) systems, restrict the duration of access, limit functionalities such as printing or copying, and prevent the transfer or long-term preservation of content. These conditions generate technological lock-in, hinder reuse over time, and eliminate the possibility of participating in secondary markets for used textbooks.
The report provides a legal framework for understanding this phenomenon by analysing the principles of copyright exhaustion and the first sale doctrine in both U.S. and EU contexts. It highlights the inconsistent and often inadequate application of these principles to digital goods, which allows publishers to retain perpetual control over digital copies and prevents consumers from exercising rights traditionally associated with ownership. As a result, significant concerns emerge regarding consumer protection, contractual fairness, transparency, and market competitiveness.
The report underscores the need for regulatory interventions ensuring interoperability across platforms, stronger rights of access and long-term preservation for students, and a more balanced relationship between copyright protection and user rights. It also highlights the potential of alternative models such as Open Educational Resources (OER), which promote accessibility, sustainability, and competition. Through this analysis, the report aims to contribute to the ongoing institutional debate and support the Authority’s assessment of possible corrective measures