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Global Sustainability in the International Arena Beyond the EU Policy Agenda
No full textIn the last decade, the EU has become a champion in the promotion of sustainability, especially in the paradigmatic terms of a Sustainable Circular Economy (SCE), but what does the landscape of the international scene look like? The chapter explores the promotion of SCE worldwide and thus addresses the question of whether the EU is a frontrunner in the transition from linear to circular economy or its role needs to be rescaled to one player among the many others that populate the international community. In fact, while the EU is surely one of the most prominent actors in this respect, it does not act in a vacuum. Many other actors took an interest the achievement of sustainability in general and in SCE in particular, and have become drivers of progressive change, in their respective geographical areas and fields of competence. The research shows that, while the EU is endowed with considerable power to influence and drive the legislative and policy agenda of Member States, other actors are, in their field of competence, promoting sustainable circular economy, consequently giving rise to a truly international and global effort from a linear economic system to a circular one
Diophantine Modeling of Provability in Algebraic Logic
No full textIt has long been established that the set Th of theorems in an axiomatic formal theory is recursively enumerable (r.e.). Building upon the Davis-Putnam-Robinson-Matiyasevich theorem, which states that every r.e. set is Diophantine, this paper explores the complexity of representing Th through a Diophantine equation D = 0. We contend that a good trade-off between two primary measures of the complexity of the representation, which are the number of unknowns and the degree of the polynomial D, should aim at the transparency of the representation. Our work builds on a previous construction, notably that of M. Carl and B.Z. Moroz, who have provided a Diophantine representation of the sentences provable in the Gödel-Bernays class theory (NBG) within first-order predicate calculus. In contrast, our Diophantine representation of NBG relies on a modernized version of Schröder’s algebra of relations, specifically the L× equational calculus proposed by A. Tarski and S. Givant. Additionally, we replace NBG’s traditional axioms with an alternative axiomatization by H. Friedmann. These changes reduce the complexity of the Diophantine representation of NBG’s provability, while maintaining equivalence to more classical formalizations. While we provide only preliminary insights into this novel equational axiomatization, we report on initial experiments with these axioms using the Vampire theorem prover
Real-life experience with a “modified-MEMMAT” regimen for relapsed medulloblastoma
No full textBackground: Medulloblastoma (MB) relapse is typically resistant to available treatments. An emerging alternative strategy focuses on disrupting tumor angiogenesis at various stages, using a combined metronomic anti-angiogenic approach. Objectives: The study aims to assess the efficacy and safety of this modified treatment approach in managing recurrent MB in the pediatric population. Designs: This study is a retrospective observational analysis involving 14 pediatric patients diagnosed with first or multiple recurrences of MB. Methods: We analyzed clinical, molecular, radiological, and outcome data of our cohort treated using a modified Medulloblastoma European Multitarget Metronomic Anti-Angiogenic Trial (MEMMAT) strategy. Results: Median age of patients was 11.6 years (range: 6.4–26 years). All 14 patients presented with a metastatic relapse after conventional treatments. The median time from primary diagnosis/prior relapse to the start of “modified MEMMAT” was 22 months (range: 2–60 months). Fifty-seven percent received the “modified MEMMAT” schema as second-line treatment, while 43% received it as third-line or beyond after recurrence. At a median follow-up of 17.9 months, the median overall survival (OS) from the MEMMAT start date was 18.2 months, and the median progression-free survival (PFS) was 12.8 months. OS at 12 and 24 months was 78.6% and 28.6%, respectively. PFS at 6 and 12 months was 100% and 55.0%, respectively. Treatment was globally well tolerated. Conclusion: The modified MEMMAT strategy shows promise in treating recurrent MB, achieving a 12-month OS rate from date of starting treatment of 78.6%, with manageable toxicity. These findings suggest its potential as a viable option for heavily pre-treated pediatric patients, warranting further validation in larger prospective studies
D'Holbach's Critique of the Scholium Generale and the Reception of Newton's Theology in the French Enlightenment
No full textThe purpose of this essay is to examine d’Holbach’s critique of Newtonian theology in
the System of Nature (1770), a topic that has not been investigated so far. D’Holbach dissects Newton’s General Scholium and rejects both the traditional Christian apologetic use of Newtonian science, and its deistic interpretation proposed in France by Voltaire. D’Holbach’s critique is illustrated here against the background of the reception of the relationship between Newton’s theology and science in the French Enlightenment, which has been reconstructed with reference to Voltaire, Maupertuis, d’Alembert, Condillac, Diderot and several articles of the Encyclopédie. It is significant that the French philosophes were fully aware that Newton’s intellectual activity was not limited to physics, but also included religion and theology. Alongside the deistic reading of Newtonian physics, a gradual methodical separation of scientific theories from their metaphysical background developed in authors such as Maupertuis, Condillac and d’Alembert. As for Diderot and d’Holbach, they elaborated a new dynamic conception of matter, influenced by chemistry and the life sciences, and thus also distanced themselves from Newton in terms of their conception of nature. D’Holbach recognized the fundamental relevance of Newtonian physics, and regarded it to be intrinsically atheistic, as an explanatory theory of the laws of nature, compatible only with an integrally materialistic philosophical system
Mindfulness-Oriented Professional Resilience (MOPR) Training to Reduce Compassion Fatigue in Healthcare Workers: A Pilot Study
Get PDFBackground/Objectives: Compassion Fatigue (CF) is a critical issue among healthcare professionals, exacerbated by exposure to trauma and chronic workplace stress. This pilot study evaluates the effectiveness of a Mindfulness-Oriented Professional Resilience (MOPR) program, a structured intervention designed to mitigate CF and enhance resilience in healthcare professionals. The program integrates mindfulness practices, arousal modulation techniques, and resilience-building strategies over six weekly sessions. Methods: A sample of 73 healthcare workers (mean age 48.6, SD = 9.42) participated in the study, and pre–post data were analyzed using repeated measures ANOVA. Results: Results indicated significant improvements in professional quality of life, with increased Compassion Satisfaction (p < 0.001) and reductions in Burnout (p = 0.003) and Secondary Traumatic Stress (p < 0.001). Mindfulness skills improved significantly across four dimensions—Observing, Describing, Acting with Awareness, and Non-reactivity—with p-values ranging from <0.01 to <0.001. Arousal modulation showed increased Optimal Arousal Zone scores (p < 0.001) and reduced maladaptive stress responses, including Fight/Flight, Freeze, and Feigned Death (p < 0.05). Psychological well-being improvements were observed, particularly in Self-Acceptance (p = 0.014) and Positive Relations (p = 0.041). Conclusions: These findings suggest that the MOPR program is a promising intervention for healthcare professionals, supporting resilience and reducing the psychological burden of caregiving. Future controlled studies should explore its long-term efficacy in diverse clinical settings and in larger samples
La critique du structuralisme normatif de Achille Ardigò
No full textPour comprendre l’influence de la pensée des sociologues français chez Achille Ardigò, deux essais écrits à trente ans d’intervalle ont été choisis : le premier, publié en 1958, propose une discussion sur les théories sociologiques de la structure sociale tandis que le deuxième propose une réflexion sur le dépassement possible de la sociologie « postmoderne » qui s’est établie entre la fin des années Soixante et le début des années Quatre-vingt, et en particulier sur les variantes du structuralisme antihumaniste et de l’individualisme méthodologique.
Malgré la diversité des sujets abordés, il existe un fil conducteur qui relie les deux textes. Ardigò, en effet, traite des sujets à partir de l’apport théorique des sociologues qui l’ont précédé ou qui sont contemporains et s’appuie, inévitablement, sur la pensée des grands classiques à travers une analyse critique des concepts qu’ils proposent. Bien que les textes aient été écrits avec trente ans d’intervalle, il y a un thème qui accompagne l’auteur dans le temps : la relation entre le sujet et la sociéte
I religiosi
No full textLe popolazioni europee della prima età moderna condividono un sistema di valori e una mentalità permeati dalla fede in un unico dio, fonte di norme, comportamenti, ideali che guidano e regolano la loro vita, le loro scelte, le loro preoccupazioni. A metà ‘400 ancora non guardano a ovest e non immaginano il mondo strabiliante degli indigeni americani, con il loro paganesimo fuori tempo, fuori luogo, fuori ragione, capace di mettere a repentaglio le loro convinzioni plurisecolari, la stessa veridicità del testo su cui si fondano i loro saperi: la Bibbia. Ed è ancora di là da venire l’impegno missionario nel lontano oriente: India, Cina, Giappone ... Ma a partire dal XVI secolo, proprio il confronto con genti e culture profondamente diverse diventerà il principale motore del loro sviluppo, oltre che economico e sociale, culturale, costringendole a mettere in campo strategie contraddittorie, metodi di conquista violenti e coercitivi accanto a più sofisticate tecniche di assimilazione e conversione, in un incontro-scontro con l’”altro” che dura tuttora. In tale quadro si configura l’avventurosa esperienza – fatta di conflitti, rotture, collaborazioni – che determina la crisi dei vecchi ordini religiosi e la nascita di nuove congregazioni, maschili e femminili, protagonisti di un’esperienza religiosa con una forte impronta educativa, missionaria e politica su scala globale
Well-being at school
No full textWell-being is a multidimensional construct, and refers to a set of objective (economic, cultural, environmental, physical) and subjective (psychological, emotional, affective, socio-relational) conditions that the individual experiences, and several studies have confirmed the existence of a close positive relationship between class climate and well-being and between well-being and learning (Govorova et al., 2020).
From the perspective of an action-research path, this research was carried out on 553 children attending the third, fourth and fifth grades of some primary schools in north-eastern Italy, and explored the conditions that make children feel good or bad at school, especially in the relationship with classmates and teachers. The relationships that bring well-being are first and foremost affective, and concern sharing one's time and space with friends, but also social and cognitive. The well-being of children is not a selfish well-being, because they are also attentive to what happens to their classmates, and if one of them manifests difficulties, they work to help him or her overcome the difficult moment and, implicitly, to re-establish a good emotional climate in the classroom. In the relationship with the teacher, what produces greater well-being is the possibility that the children carry out activities that they enjoy, but also the recognition and appreciation for what the children do. Finally, a fundamental role is assigned to the teacher in intervening when pupils behave badly, in order to bring back a good climate in the classroom and promote everyone's well-being