University of Udine
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The role of legal medicine in the reconstruction of fatalities due to tractor rollovers: from evidence to proof
No full textDespite advances in engineering solutions, such as rollover protective structures and improved operator training, tractor rollovers in agricultural settings continue to be the main cause of death necessitating medicolegal investigations to reconstruct event dynamics and determine causal attributions. This study examines the distinction between evidence (observational data consistent with a hypothesis) and proof (conclusive data confirming a hypothesis) in the context of fatal tractor accidents. We propose a three-phase logic model which provides a conclusive reconstruction of the events by integrating engineering data, dynamic modelling, death scene analysis and autopsy findings. Careful analysis of the death scene and circumstantial evidence is essential during investigations of rollover dynamics, encompassing operational safety procedures, the technical characteristics of the vehicle, corpse position, autopsy findings, toxicology data, the victim's medical history and psychophysical condition at the time of the accident occurred. Systematizing such variables within a unified forensic framework enhances the scientific reliability of forensic investigations and the technical reconstruction of the fatality, thus contributing to the development of prevention strategies, liability assessment and the formulation of safety policy
High JAK2V617F allele burden in low-risk PV: an additional recommendation to start “early” cytoreduction? Results from a multicentric study
No full textLa fase decisoria
No full textLa fase decisoria costituisce il terzo e ultimo stadio del procedimento di cognizione di primo grado dinanzi al tribunale. Il presente capitolo è dedicato alla forma di tale fase, ossia allo studio degli atti che sono compiuti durante il suo corso. In quest’ambito, ove le riforme succedutesi nel tempo hanno introdotto la figura del giudice unico quale organo decidente alternativo al collegio, i temi principali sono costituiti dai presupposti della rimessione in decisione, dal contraddittorio conclusionale, dalla composizione dell’organo giudicante e dalla formazione del provvedimento con cui il potere giudiziario manifesta la volontà dello Stato nei rapporti tra privati
Il sito Unesco Palù di Livenza-Santissima. Tutela e valorizzazione tra archeologia e paesaggio
No full textIl sito Palù di Livenza-Santissima, iscritto nella serie transnazionale Unesco "Prehistoric Pile Dwellings around the Alps", si trova in un’area umida del Friuli Venezia Giulia di rilevante interesse archeologico, paesaggistico e naturalistico. Il contributo analizza l’evoluzione storica e l’inquadramento giuridico del sito, esaminando la complessa interazione tra vincoli di tutela, pianificazione paesaggistica e gestionale, per evidenziare le peculiari connessioni che intercorrono tra paesaggio e diritto
Life Care Reverse Mortgages: monitoring the net cashflows of a new hybrid insurance product
No full textCombining retirement income and long-term disability protection is a well-established
concept in the literature. We present a new connection between the
lifetime annuity provided by a Reverse Mortgage and long-term care (LTC) insurance,
jointly managed in a unique bundled product. Indeed, we define the RM
(considered as a source of lifetime income) and LTC as two different regimes of a
jointly managed insurance product, which we call the "Life Care Reverse Mortgage”
(LCRM). From an actuarial perspective, we design the underlying structure of the
LCRM and the inherent framework for the ex-ante estimation of a time-dependent
profit/loss function, that provides a measure of the expected annual net cashflows
for a life insurer holding a portfolio of LCRMs. We perform a numerical application
to illustrate the regime-switching mechanism on which the proposed LCRM
insurance contracts are based and to quantify over time the lender’s return for a
pool of LCRM contracts through the designed time-dependent profit/loss function.
Furthermore, we analyse the sensitivity of the portfolio profit/loss function to two
sources of uncertainty: health patterns over time and house price dynamics
Correction: Management of Patients with Vulvar Cancers: A Systematic Comparison of International Guidelines (NCCN–ASCO–ESGO–BGCS–IGCS–FIGO–French Guidelines–RCOG) (Cancers, (2025), 17, 2, (186), 10.3390/cancers17020186)
No full textThere was an error in the original publication [1], regarding the cited reference [52]. The citation referred to “Tagliaferri, L.; Garganese, G.; D’Aviero, A.; Lancellotta, V.; Fragomeni, S.M.; Fionda, B.; Casà, C.; Gui, B.; Perotti, G.; Gentileschi, S.; et al. Multidisciplinary personalized approach in the management of vulvar cancer—The Vul.Can Team experience. Int. J. Gynecol. Cancer 2020, 30, 932–938”. However, the results described in that paragraph more accurately correspond to the article by Maggino et al.: “Maggino, T.; Landoni, F.; Sartori, E.; Zola, P.; Gadducci, A.; Alessi, C.; Soldà, M.D.; Coscio, S.; Spinetti, G.; Maneo, A.; et al. Patterns of recurrence in patients with squamous cell carcinoma of the vulva: A multicenter CTF study. Cancer 2000, 89, 116–122.” The original reference has now been replaced with the new one. The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated
Searching Agricultural Learning Experiences in the Metaverse via Textual and Visual Queries Within the AgriMus project
No full textEvery day, social media and content sharing platforms receive numerous training videos across a multitude of sectors, including home gardening, agriculture, and indoor farming. Recently, the Metaverse has offered the opportunity to create enclosed virtual spaces where a user can focus and learn specialized skills, e.g., medical, in an easy, interactive, and engaging way. However, finding suitable educational spaces for specific themes remains a challenge. In light of these advancements and to support agricultural education, in this work, we introduce AgriMus project, which aims to design agricultural-themed museums covering a broad range of topics. Users can explore and retrieve specific educational experiences through visual or textual queries. Beyond creating a dataset for the agricultural setting, we also propose a hierarchical method to model these virtual museums. Several experiments have been conducted to evaluate the effectiveness of the proposed approach. The full source code and dataset used in this study are available at: https://github.com/aliabdari/AgriMus/
LA NUOVA RILEVANZA DELL’ART. 1, COMMA 1, DELLO STATUTO DEI DIRITTI DEL CONTRIBUENTE
No full textL’evoluzione dello Statuto dei diritti del contribuente e i nuovi principi sovraordinati. I riflessi sull’ordinamento tributario e sulla sua europeizzazione. Prime conclusion
Robotic single-port (da Vinci SP) versus multiport (da Vinci Xi) for the treatment of atypical endometrial hyperplasia and endometrial cancer: A multi-institutional comparison of surgical outcomes
No full textIntroduction: The da Vinci SP robotic platform offers a novel single-port approach for minimally invasive surgery. Despite its potential, data on its safety and performance in gynecologic oncology remain limited. We aimed to compare surgical outcomes of da Vinci SP versus da Vinci Xi systems in the staging of endometrial cancer (EC). Methods: This is a multi-institutional study. Data of consecutive patients with apparent early-stage EC or atypical endometrial hyperplasia who underwent robotic surgery between January 2023–March 2025 were collected. The primary outcome was to compare the surgical outcomes between da Vinci SP and da Vinci Xi. Results: A total of 189 patients were included: 97 (51.3 %) underwent SP surgery and 92 (48.7 %) Xi. The median (range) of operative time, estimated blood loss, and postoperative hospital stay were comparable for SP and Xi groups (140 [70–296] vs. 143 [60–297] min, p = 0.66, 40 [0–250] vs. 64 [0–1300] mL, p = 0.12, 3 [1–11] vs. 3[1–10] days, p = 1). Docking time was significantly shorter in the SP group (10 [4–31] vs. 12 [7–30] min for SP and Xi, respectively, p = 0.004). Intraoperative or post-operative complications rates were comparable (p = 0.30 and p = 0.14,respectively). The patient-reported pain score was significantly lower at 12h and 24h in the Xi group (p = 0.001), while was comparable at 48h after surgery (p = 1). Conclusion: The da Vinci SP system appears to be non-inferior to the multiport da Vinci Xi for surgical staging of early-stage EC. Comparable perioperative outcomes support its clinical use, although patient selection criteria and long-term results require further investigation
An International Inter-Consortium Validation of Knowledge-Based Plan Prediction Modeling for Whole Breast Radiotherapy Treatment
No full textBackground: Knowledge-based (KB) planning is a promising approach to model prior planning experience and optimize radiotherapy. To enable the sharing of models across institutions, their transferability must be evaluated. This study aimed to validate KB prediction models developed by a national consortium using data from another multi-institutional consortium in a different country. Methods: Ten right whole breast tangential field (RWB-TF) models were built within the national consortium. A cohort of 20 patients from the external consortium was used for testing. Transferability was defined when the ipsilateral (IPSI) lung first principal component (PC1) was within the 10th–90th percentile of the training set. Predicted dose–volume parameters were compared with clinical dose–volume histograms (cDVHs). Results: Planning target volume (PTV) coverage strategies were comparable between the two consortia, even though significant volume differences were observed for the PTV and contralateral breast (p = 0.002 and p = 0.02, respectively). For the IPSI lung, the standard deviation of predicted mean dose/V20 Gy was 1.13 Gy/2.9% in the external consortium versus 0.55 Gy/1.6% in the training consortium. Differences between the cDVH and the predicted IPSI lung mean dose and the volume receiving more than 20 Gy (V20 Gy) were <2 Gy and <5% in 88.7% and 92.3% of cases, respectively. PC1 values fell within the 10th–90th percentile for ≥90% of patients in 6/10 models and 65–85% for the remaining 4. Conclusions: This study demonstrates the feasibility of applying RWB-TF KB models beyond the consortium in which they were developed, supporting broader clinical implementation. This retrospective study was supported by AIRC (Associazione Italiana per la Ricerca sul Cancro) and registered on ClinicalTrials.gov (NCT06317948, 12 March 2024)