University of Udine
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Particle-laden flows
No full textParticle-laden flows are encountered in countless technological applications and natural processes, thus playing a pivotal role in the field of multiphase flow. What is fascinating about particle-laden flows is their marked multiscale nature, which is accompanied by a variety of small-scale phenomena that govern the macroscopic flow behavior. Because of this, modeling, measuring and simulating the dynamics of the particles and their interaction with the flow has always posed formidable challenges to the scientific community. Despite these challenges, the combined efforts of the community have led to significant progress in the understanding of the fundamental aspects, which we survey in this synoptic review. In particular, we explore the different features of particle–fluid interaction and their dependence on the particle and flow properties. Starting from the case of a single particle interacting with the flow, we discuss situations of increasing complexity like particle–particle interactions and collective particle dynamics. Situations in which particles evolve in complex flows, in particular turbulent ones, or inside complex fluids, e.g. non-Newtonian ones, are also discussed. The review ends by providing an outlook on the future directions that are expected to drive research in the coming years and the open issues that must be addressed to ensure further progress of the knowledge
The Roles of Kinesio Tape and Manual Lymphatic Drainage in Post-operative Management of Lipoabdominoplasty
No full textWhat Are the Perceptions of Recipients of Allogeneic Hematopoietic Stem Cell Transplant About Medication Adherence? A Synthesis of Qualitative Studies
No full textBackground: Recipients of allogeneic hematopoietic stem cell transplant (HSCT) may encounter difficulties in adhering to their post-transplant medication as prescribed to avoid complications. Despite the relevance of patients' perspectives to inform the clinical practice, to date, no summary regarding their lived experience of oral medication adherence (MA) has been produced. Objective: To summarize the lived experience of MA by recipients of allogeneic HSCT as documented in qualitative studies. Methods: A systematic review and meta-synthesis of qualitative research was performed. Six databases were searched up to June 27, 2023. Four qualitative studies met eligibility and were included: those designed and conducted with scientifically sound methodologies and those regarding adult patients who had undergone allogeneic HSCT and required an oral medication regimen in the post-transplant phase. Data were extracted and synthesized using thematic analysis. Results: Four analytical themes were identified: "The initiation is a challenge," "Time as a new issue," "Internal and external obstacles threaten medication adherence," and "Different strategies are the answer to medication non-adherence." Conclusions: Medication adherence in patients after HSCT is a complex phenomenon wherein different factors play a role. When designing targeted interventions to improve MA, it is imperative to start with patients' experiences and perspectives. Implications for practice: Patients developed different strategies to deal with obstacles to MA that may inform daily practice. Before discharge, healthcare professionals should emphasize to both patients and carers the importance of MA
Responses of Alpine grassland plants to heat wave: analysis of selected physiological parameters.
No full textRamon J. Pujades i Bataller, Els mapamundis baixmedievals: del naixement del mapamundi híbrid a l’ocàs del mapamundi portolà / Late Medieval World Maps: From the Birth of the Hybrid to the Demise of the Portolan Mappamundi
No full textAlcune riflessioni sullo spazio linguistico in aree di migrazione
No full textAnalisi della variazione linguistica che attraversa le comunità italofone e dialettofone di lingua minoritaria in contesti migratori come banchi di prova per le indagini sul plurilinguismo migratorio, sulla dinamiche sociolinguistiche e sui fenomeni di contatto interlinguistico
Impaired nitric oxide-dependent endothelial function in young male individuals with obesity before the onset of symptoms and complications
No full textEndothelial dysfunction drives obesity-related complications. Doppler ultrasound measurement of blood flow during 1-min passive leg movements (PLM) is a valuable non-invasive tool for assessing endothelial function and nitric oxide (NO)-mediated vasodilation. The objectives of this work were t o identify endothelial dysfunction biomarkers in young individuals with obesity (OB) using the PLM test; to evaluate the effects of a rehabilitation programme on these biomarkers; and to explore associations between PLM data, oxidative metabolism and blood biomarkers of microvascular impairment. Fifteen male OB (age 17 ± 4 years; body mass 121.4 ± 24.1 kg; body mass index 39.3 ± 7.5 kg m−2) were tested before (PRE) and after (POST) a 3-week multidisciplinary body mass reduction programme. Fifteen age-matched normal-weight males (CTRL) underwent PRE measurements. Participants performed an incremental exercise, a PLM test and underwent blood biomarker analysis. Peak oxygen uptake and ventilatory thresholds (mL kg−1 min−1) were ∼40% lower in OB versus CTRL (P < 0.001) and improved by ∼8% in OB POST versus PRE (P < 0.05). Plasma nitrite concentration was lower in OB (0.18 ± 0.09 μmol L−1) versus CTRL (0.51 ± 0.49; P = 0.02). Baseline blood flow, normalized for appendicular muscle mass, was similar between the two groups, whereas peak blood flow, Δpeak (difference between peak and baseline) and the area under the blood flow versus time curve were significantly lower in OB PRE, with improvements in OB POST. Several blood biomarkers of endothelial barrier function and permeability differed in OB versus CTRL. The blunted PLM-induced hyperaemic response and lower plasma nitrite levels indicate impaired endothelial function in young individuals with obesity, occurring before the onset of cardiovascular and metabolic complications
Assessment of the fiscal stance approprtiate for the euro area in 2026
No full textThe EFB is of the view that, excluding defence spending, fiscal restraint is appropriate in 2026, along the lines of the Council recommendations of January 2025. Flexibility under the national escape clauses should be limited strictly to ramping up defence spending. To bolster the credibility of their public finances, Member States resorting to the national escape clause should outline robust medium-term strategies for financing permanently higher defence spending starting with the draft budgetary plans for 2026. The medium-term strategies should involve commensurate adjustments on the expenditure and/or the revenue side of national budgets
Donors Infectious Risk Stratification: Activity of the Italian National Transplant Center
No full textBackground: The use of organs from donors at increased infectious risk represents an effort to broaden the donor pool, but case-by-case evaluation may be needed. The Italian National Transplant Center (CNT) is supported by a second opinion task force of experts consulted for donors with complicated infectious assessment. Methods: Retrospective observational study to describe infectious disease second opinion (IDSO) activity between June 2022 and October 2023. We analyzed the distribution of the infectious risk level, assigned according to the CNT protocol in five categories. Results: IDSO evaluation was requested for 1246 of the 4153 (30%) of the donors. The mean age was 58.2 years, 56.8% were male, and most of them were Italians (91%). Donors had on average 1.5 (SD 0.9, range 1–6) infectious problems, the most frequent being pneumonia (453, 36.4%), inflammatory marker elevation (299, 24%), and bacteremia (125, 10%). The infectious risk was classified in most cases as increased but acceptable risk (60.8%), followed by negligible risk (19.2%) and increased but acceptable risk only for critical recipients (12.4%). Only 5.2% of donors were unacceptable, the main reason being inappropriately treated multidrug-resistant organism bacteremia or candidemia (21/65, 32.3%). Lung was the most frequently excluded organ (18.2%). In 284 donors (24%), additional testing was recommended, and in 299 recipients (25.3%), a specific therapeutic indication was given. Conclusions: IDSO activity allowed the acceptance of the donor pool in almost 95% of the reviewed cases. Prospective international studies are necessary to understand the real impact of donors at increased infectious risk on recipient outcomes
