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Cultural and organizational challenges of adopting technology, traceability and blockchain in the Italian agri-food supply chain: a qualitative study
No full textElectrical brain activity in Centenarians: Neurophysiological EEG markers in resilient brain ageing
No full textCentenarians are an increasing population, in particular in high income countries. Studying cognitively intact Centenarians’ brain becomes fundamental to understand physiological ageing and how it diverges from pathological one. Resting state EEG were recorded using 27 channels in more than 130 subjects (referred to Young, Adults, Elderly, Centenarians and Alzheimer Disease patients), and the power spectral density (PSD) was computed. The paper demonstrates that Centenarians electrical brain activity is more similar to Elderly's than expected, despite approximately 30 years of age gap, provided they are cognitively intact. Centenarians EEG signal was expected to progressively approach AD one, but surprisingly they seem to slow-down their ageing and maintain non-pathological and resilient EEG patterns, particularly in Alpha bands: occipital region Centenarians PSD has lower values than Young and Adults but not than Elderly, and higher values than AD. These interesting results suggests that Centenarians brain needs to be investigated to extrapolate its characteristics and try to replicate its mechanisms for a widespread healthy ageing
The CORTEX Project: A Pre–Post Randomized Controlled Feasibility Trial Evaluating the Efficacy of a Computerized Cognitive Remediation Therapy Program for Adult Inpatients with Anorexia Nervosa
No full textBackground/Objectives: Anorexia nervosa (AN) is marked by cognitive deficits, particularly reduced mental flexibility and weak central coherence, which may sustain the core psychopathological symptoms. While cognitive remediation therapy (CRT) has shown efficacy in improving these cognitive processes in AN, evidence on computer-based CRT remains limited. This study aims to evaluate the feasibility and efficacy of integrating computer-assisted cognitive remediation therapy (CA-CRT) into standard nutritional rehabilitation (treatment as usual, TAU) to improve the targeted cognitive and psychological parameters among inpatients with AN in a more personalized and scalable way. Methods: A multicenter randomized controlled trial (RCT) will be conducted. At least 54 participants with a diagnosis of AN will be recruited at each site and randomized into either the experimental or control group after initial screening. The intervention will last five weeks and include 15 individual CA-CRT sessions alongside 10 individual CR sessions, delivered in addition to standard care. The primary and secondary outcomes will be assessed at the end of the intervention to evaluate the changes in cognitive flexibility, central coherence, and psychological functioning. Results: Participants receiving CA-CRT are expected to develop more flexible and integrated thinking styles and achieve greater improvements in clinical outcomes compared to those receiving standard care alone, supporting a more personalized therapeutic approach. Conclusions: These findings would underscore the feasibility and clinical value of incorporating CA-CRT into standard inpatient treatment for AN. By specifically targeting cognitive inflexibility and poor central coherence in a scalable, individualized format, CA-CRT may enhance treatment effectiveness and support the development of patient-centered interventions tailored to the cognitive profiles of individuals with AN
Enhancing cardiovascular screening in master athletes: the role of exercise stress echocardiography
No full textBackground: Cardiovascular (CV) disease is a significant risk even among seemingly healthier populations like master athletes, who face unique CV challenges due to their advanced age and high-intensity physical activities. Exercise stress echocardiography (ESE) has emerged as a valuable diagnostic tool to detect exercise-induced coronary artery disease (CAD), offering advantages over traditional exercise stress testing (EST) by integrating echocardiographic imaging. This article aimed to assess the diagnostic value and efficacy of ESE for detecting CAD in master athletes who exhibit exercise-induced alterations during pre-participation screening (PPS) EST. Methods: This retrospective study analyzed 521 master athletes (aged 35 years and older) who underwent annual CV assessments including EST as part of their PPS at Noale Hospital, Venice, Italy, from September 2020 to August 2023. Participants who showed exercise-induced alterations suspicious for CAD on EST were further evaluated using ESE. Results: Of the 521 athletes screened, 58 (11.1%) exhibited suspicious alterations for CAD during EST. ESE further identified 13 athletes with wall motion abnormalities (WMA), of whom 10 were subsequently diagnosed with critical CAD and received appropriate interventions. The positive predictive value of ESE was 0.77. Comparatively, athletes with WMA had significantly higher CV risk scores. No major adverse CV events (MACE) were reported during the 43.9-month follow-up. Conclusions: ESE is an effective third-line diagnostic tool in master athletes, demonstrating a high diagnostic yield for identifying significant CAD. Its integration into routine CV screening for master athletes can enhance the detection of underlying pathologies, potentially leading to timely and life-saving interventions
Sinergie tra Universal Design for Learning, co-teaching e tecnologie digitali per un’educazione inclusiva
No full textNell’ambito della crescente attenzione verso l'inclusione scolastica e la personalizzazione dell’insegnamento, questo studio indaga come l’Universal Design for Learning (UDL), il co-teaching e le tecnologie digitali si integrino nelle pratiche didattiche inclusive dei docenti. L’ipotesi è che l’adozione sistematica di strategie UDL, l’implementazione del co-teaching e l’uso intenzionale delle tecnologie digitali siano correlati positivamente con livelli più elevati di inclusione percepita e con l'efficacia didattica. Per esplorare queste dinamiche, è stato utilizzato un approccio metodologico misto, combinando analisi quantitative e qualitative. L’indagine ha permesso di raccogliere 1090 risposte attraverso la somministrazione di uno strumento di indagine ai docenti iscritti al IV ciclo dei percorsi abilitanti da 30 CFU (ex art. 13) presso l’Università e-Campus. I risultati evidenziano che la LIM è la tecnologia UDL più diffusa, mentre le tecnologie assistive sono meno utilizzate. Il co-teaching risulta praticato da molti insegnanti per migliorare il coinvolgimento degli alunni, sebbene ostacolato da carichi di lavoro e scarsa possibilità di pianificazione condivisa. Le strategie UDL sono mediamente più adottate delle pratiche collaborative e risultano positivamente correlate al co-teaching. Lo studio evidenzia come l’inclusione scolastica dovrebbe essere un principio fondamentale della progettazione didattica, integrando UDL, co-teaching e tecnologie digitali in linea con una prospettiva pedagogica dell'equità
Sagittal Spinal Alignment in Children and Adolescents: Associations with Age, Weight Status, and Sports Participation
No full textBackground. Poor posture is a common musculoskeletal concern in children and adolescents and may lead to spinal discomfort and long-term structural issues. While excess weight has been linked to altered sagittal alignment, the impact of sports participation on spinal posture remains unclear. This study aimed to investigate the associations between weight status, sports participation, and sagittal spinal alignment in a pediatric population. Methods. This cross-sectional study was conducted within the “Ferrari Formula Benessere” corporate wellness program and included 698 children aged 5 to 16 years. Sagittal Index (SI) was measured using a standardized plumb line technique. Body mass index (BMI) was calculated and classified according to the WHO growth standards. Sports participation was self-reported and grouped into five categories: sedentary, skill-based, power-based, mixed, and endurance sports. Results. Age was the only significant independent predictor of the SI (β = 2.45, p < 0.001), with older children exhibiting higher SI values. Although a weak correlation was observed between BMI and SI (Spearman’s r = 0.24, p < 0.001), BMI was not a significant predictor when controlling for age. No significant differences in the SI were found between active and non-active children. Among sport disciplines, the SI was lowest in power-based sports (56.7 ± 22.3 mm) and higher in endurance (62.7 ± 24.4 mm), mixed (64.5 ± 23.2 mm), skill-based (61.1 ± 22.0 mm), and non-sport (64.2 ± 24.0 mm) groups, although these differences did not reach statistical significance (ANOVA p = 0.224). Conclusions. Age appears to be the primary factor associated with sagittal spinal alignment in children, while BMI and general sports participation showed no independent effect. Although some differences emerged between sport types, these findings were not statistically significant and should be interpreted with caution. These findings underscore the need for sport-specific, longitudinal research using objective posture assessment methods