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Considerazioni sulla battaglia di Ilipa o Silpia
No full textCome fu combattuta la battaglia di Ilipa e sua importanza nella guerra contro i Cartaginesi in Hispania nel corso della seconda guerra punic
Effects of an exercise-based rehabilitation program in patients with minor ischemic non-disabling stroke or transient ischemic attack
No full textBACKGROUND: Ischemic stroke and transient ischemic attack (TIA) present global health challenges. While physical activity is strongly recommended for secondary prevention of these clinical conditions, there’s a massive gap between guidelines and the real world. This study aimed to assess the effectiveness, safety, and feasibility of an exercise-based rehabilitation (EBR) program for patients with minor ischemic non-disabling stroke (MINDS) or TIA. METHODS: Consecutive patients from the Neurology Unit of Mirano – Venice, Italy, diagnosed with MINDS or TIA, underwent a structured EBR program. The program comprised 6 weeks of supervised training in a hospital gym and 12 months of territorial gym training. Safety, feasibility, and effectiveness were evaluated through adverse events, drop-out rates, and improvements in body composition, muscular strength, and cardiopulmonary fitness. RESULTS: The sample comprised 32 patients (mean age 66 years, 81,3% male). No adverse events were reported. During the in-hospital phase of the program, there were no dropouts, while 28% of patients ceased training during the territorial phase. After the in-hospital phase, there were significant improvements in body composition, muscular strength, and cardiopulmonary parameters. These benefits persisted at the 12-month territorial gym phase of the EBR program only for patients who continued training. CONCLUSIONS: The structured EBR program demonstrated safety, feasibility, and effectiveness in improving health parameters for MINDS or TIA patients. Such interventions promise to enhance secondary prevention and overall health outcomes in this patient group
Jeu et technologies numériques à l'école maternelle: le modèle « jouer pour apprendre »
No full textCette étude vise à effectuer une revue de la littérature pour examiner les effets possibles de l'utilisation d'appareils et de technologies numériques sur les processus d'enseignement et d'apprentissage des enfants de 3 à 6 ans qui fréquentent les écoles maternelles dans des contextes et des situations ludiques.
En partant de l'hypothèse que le jeu mobilise toute une série de langages (cognitif, relationnel, social, créatif et récréatif), de la reconnaissance que chaque enfant rencontre et se confronte aux nouveaux médias à la fois en tant que spectateur et acteur, et que l'école peut l'aider à se familiariser avec l'expérience des multimédias, nous avons mis en œuvre une revues systémiques pour étudier comment les écoles maternelles accompagnent les enfants dans leur expérience avec les médias numériques.
Plus précisément, nous aimerions ensuite explorer le domaine de recherche didactique-technologique à partir de la question suivante : "Quelle interaction pouvons-nous envisager entre le jeu (dimension ludique) avec l'utilisation des technologies numériques et l'apprentissage (dimension le "jeu pour apprendre" ) avec des enfants d'âge préscolaire ?".
À cet égard, il est jugé approprié de circonscrire le concept de « jeu éducatif », c'est-à-dire de faire référence à l'intervention didactique en vue de la reconstruction intellectuelle d'expériences ludiques à l'aide de dispositifs numériques, spécialement préparés par l'enseignant pour les enfants.
Le scénario présenté conduit à un examen approfondi des stratégies ludiques-éducatives dans les écoles maternelles et, en particulier, à la question de savoir si les éléments qui composent le modèle « jouer pour apprendre » peuvent être ⎼ en tout ou en partie ⎼ dans le cadre du jeu avec les nouveaux médias.
Pour cette raison, une étude des contributions publiées dans ce domaine d'étude particulier est réalisée afin de retracer et de diffuser les résultats de la recherche obtenus jusqu'à présent et d'identifier les voies possibles pour un développement ultérieur
Il campo come ricerca e narrazione dell’etnografia. L’etnografia come archivio della memoria
No full textIl lavoro di ricerca che viene presentato nelle pagine che seguono parte dal concetto di ricerca
storiografica per poi indicare diverse direttrici di ricerca in relazione agli archivi, ai musei e
all’etnografia. Il senso di nuova storia, nella ricerca sul campo, scaturisce dal sovrapporsi
dell’analisi empirica ai luoghi simbolici della memoria, appunto musei e archivi. Il senso è quello
di comprendere che le scienze sociali e umane, che prediligono il lavoro etnografico, si
indirizzino anche sulla ricerca di archivio come mezzo di analisi sociale
Aspetti politico-sociali nel pensiero di Kant
No full textIl saggio affronta gli aspetti politico-sociali nel pensiero di Kant, mettendo in correlazione la guerra
con le strutture sociali e politiche e riflettendo sul legame tra la morale e la politica. L’origine della
guerra va collocata nell’abito dell’assenza di uno Stato organizzato che possa regolare i rapporti tra
gli individui e che abbia la sovranità per impedire agli esseri umani di danneggiare la libertà
reciproca. Riproponendo il discorso del rapporto tra Stato e individui al livello delle relazioni tra
gli Stati, Kant ritiene che la pace perpetua possa essere raggiungibile mediante la nascita di una
federazione di Stati e di un regolamento giuridico dei rapporti tra gli Stati. Il saggio esplora la
concezione secondo la quale il culmine della natura e del “disegno della storia” è il raggiungimento
di una organizzazione sociale regolata dalle leggi dello Stato. La “garanzia” della pace viene dal
corso stesso della natura la quale fa sorgere progressivamente la concordia tra gli individui. Il saggio
si chiude con una riflessione sull’accordo tra l’idea morale della pace e la politica, che si definisce
come “idea regolativa” che comanda all’essere umano di vivere e di agire “come se” fosse possibile
il trionfo della pace, della moralità e ragione. La politica si colloca nella sfera dell’agire pratico e nel
sistema delle libertà e rappresenta l’applicazione istituzionale e pragmatica del diritto e della dottrina
giuridica
Correlative imaging integrates electrophysiology with three-dimensional murine heart reconstruction to reveal electrical coupling between cell types
No full textCardiac fibrosis contributes to electrical conduction disturbances, yet its specific impact on conduction remains unclear, hindering predictive insight into cardiac electrophysiology and arrhythmogenesis. Arrhythmogenic cardiomyopathy is associated with fibrotic remodeling, and it accounts for most cases of stress-related arrhythmic sudden death. Here we develop a correlative imaging approach to integrate macroscale cardiac electrophysiology with three-dimensional microscale reconstructions of the ventricles. We apply this tool to a desmoglein-2 mutant mouse model to characterize the dynamics of conduction wavefronts and relate them to the underlying structural substrate. We observed that conduction through fibrotic tissue areas shows a frequency-dependent behavior, where conduction fails at high stimulation frequencies; this promotes reentrant arrhythmias, even in regions that were electrophysiologically inconspicuous at lower stimulation rates. We found that fibrotic areas undergo electrophysiological remodeling that acts as a low-pass filter for conduction, quantitatively explained by computational models informed by structural data. Collectively, our study provides a structure–function mapping pipeline and describes a pro-arrhythmogenic mechanism in arrhythmogenic cardiomyopathy
Durability‐aimed performance of glass FRCM‐confined concrete cylinders: experimental insights into alkali environmental effects
No full textThis study explores the structural performance of concrete cylinders confined with glassbased fabric-reinforced cementitious matrix (FRCM) systems, emphasizing the effects of prolonged exposure to alkali-rich environments. FRCM confinement has gained attention for its ability to enhance compressive strength and ductility in concrete elements, but its long-term durability under chemically aggressive conditions remains a critical concern. In practical applications, exposure to alkaline environments— such as those found in concrete pore solutions— can significantly impact the mechanical integrity of the composite system, particularly the bond between the glass fibers and the cementitious matrix, which is essential for effective confinement. To assess these effects, an experimental program was conducted involving glass-FRCM coupons, dry fabrics, and concrete cylinders externally wrapped with glass-FRCM. These specimens were immersed in a simulated alkaline solution for durations of 1000, 2000, and 3000 h. Both confined and unconfined cylinders were subjected to axial compression tests to evaluate changes in compressive strength, axial strain capacity, and failure mechanisms. Additionally, digital microscopy was used to examine microstructural deterioration and chemical alterations in the glass fibers and matrix, providing insight into the degradation processes at the fiber-matrix interface. The results indicate that alkali exposure progressively weakens the interfacial bond between the glass fibers and the cementitious matrix, with the extent of degradation closely linked to the exposed surface area. This deterioration leads to a measurable decline in confinement effectiveness over time
Intensity-Modulated Interventional Radiotherapy (Modern Brachytherapy) Using 3D-Printed Applicators with Multilayer Geometry and High-Density Shielding Materials for the NMSC Treatment
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